Medicine and Health Sciences Commons^™

Intrahepatic-Cutaneous Biliary Fistulas Secondary To Trauma, Farouq Samhouri, James C. Gruenberg, Robert S. Brown

Henry Ford Hospital Medical Journal

Biliary fistula is an unusual complication after operations for hepatic trauma, but only scant information is available concerning its management. This report describes biliary fistulas and presents two cases of their successful resolution, by external drainage in one case and internal drainage in the other. These cases illustrate aspects of fistula management and prevention described in the literature and suggest individualized approaches.

Herpes Zoster Encephalitis: Successful Therapy With Vidarabine, Steve J. Wees, Tom Madhavan

Henry Ford Hospital Medical Journal

A 77-year-old woman was seen who had encephalitis complicating trigeminal herpes zoster. Diagnosis was made by clinical and cerebrospinal fluid findings and electroencephalogram. As a result of parenteral vidarabine therapy, the patient recovered.

Ards And Cerebral Infarction Complicating Mycoplasma Pneumonia In Sickle Cell Trait, Mark I. Pensler, Jan R. Radke

Henry Ford Hospital Medical Journal

A patient with Down's syndrome and sickle cell trait developed the adult respiratory distress syndrome and cerebral infarction during infection with Mycoplasma pneumoniae. The slow recovery of pulmonary function was unrelated to antimicrobial therapy. Sickle cell trait may be a risk factor for severe M. pneumoniae infection. The possible underlying mechanism for this relationship is explored, and the relationship between sickle cell trait, cold agglutinins, and the cerebral infarction is discussed.

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

1980 Beaumont Lecture: Restriction Enzymes As Tools For Genetic Research, Hamilton O. Smith

Henry Ford Hospital Medical Journal

No abstract provided.

Systematic Treatment Of Chronic Pain With Antidepressants, Dietrich Blumer, Mary Heilbronn, Edgard Pedraza, Gerald Pope

Henry Ford Hospital Medical Journal

Patients with chronic pain who do not have significant physical symptoms present a characteristic clinical-psychological profile and show a high incidence of depressive traits (inactivity, depressive mood, anhedonia, and insomnia). This syndrome is termed pain-prone disorder and represents a form of masked depression par excellence. A series of 129 patients with pain of 6.9 years' duration was divided into three treatment groups. Two psychiatrists prescribed antidepressants systematically by promptly increasing doses and by alternating antidepressants if indicated. Significant improvement or freedom from pain was achieved in most patients who complied with treatment.

The third psychiatrist did not follow the systematic …

The Recognition Of Active Retrolental Fibroplasia, R. Michael Nisbet

Henry Ford Hospital Medical Journal

As the incidence of retrolental fibroplasia increases, physicians must become familiar with its appearance. This report describes the examination techniques and morphology of the active and regressive stages of retrolental fibroplasia.

The Efficacy Of Biliary Diversion For Benign Disease: Long-Term Follow-Up, Farouq Samhouri, Carlos Grodsinsky, Hubert Allen

Henry Ford Hospital Medical Journal

Retrospective analysis of 70 patients who underwent biliary bypass operations for benign disease over an eight-year period was undertaken to evaluate long-term complications. Operative procedures included choledochoduodenostomy in 60 patients, choledochojejunostomy in four, and cholecystoduodenostomy, cholecystojejunostomy and hepaticojejunostomy in two patients each. The most common indication for surgery was choledocholithiasis, with or without hepatic stones, viscid bile, and ampullary stenosis (61 to 70 patients). Other indications included chronic pancreatitis, choledochal cyst, and sclerosing cholangitis. One patient died postoperatively from hemorrhage, and two others died from causes unrelated to surgery. Two patients developed cholangitis without reflux and demonstrated anastomotic stenosis at …

Danazol Therapy In Hereditary Angioedema, Lawrence C. Sweet, Charles E. Jackson, Sam S. Yanari, J. B. Yott

Henry Ford Hospital Medical Journal

Herditary angioedema (HAE) is an autosomal dominantly inherited condition in which a deficiency of the inhibitor (C1lnh) of the activated first component of complement is associated with recurrent episodes of edema of the skin, gastrointestinal tract, and larynx. The pituitary gonadotropin inhibitor, danazol, has been reported to be effective in preventing attacks and increasing C1lnh levels. Our experience with 11 patients from five kindreds corroborated those results and has revealed that most patients can be maintained symptom-free on 100-200 mg of danazol daily Side effects were minimal, although one young woman discontinued therapy because it aggravated her acne. The elevation …

Henry Ford Hospital Clinicopathological Conference: Metamorphosis In Chronic Granulocytic Leukemia In A 60-Year-Old Man

Henry Ford Hospital Medical Journal

No abstract provided.

Skin Lesions Associated With E. Coli Sepsis In A Patient With Acute Leukemia, Robert A. Chapman, Ellis J. Van Slyck, Tom Madhavan

Henry Ford Hospital Medical Journal

The clinical course of a patient with acute leukemia and metastatic intradermal abscesses secondary to Escherichia coli sepsis is described. E. coli organisms, cultured first from the blood and later from the lesions, had an identical antibiotic susceptibility and biotyping profile. This complication has not been previously described. Granulocytopenia and varicose veins may have been critical predisposing factors. With more widespread use of progressive immunosuppressive regimens, unusual manifestations of common infections will be recognized more frequently.

Hypomagnesemia-Lnduced Cardiac Arrhythmia, Robert Chapman, Jan Rival

Henry Ford Hospital Medical Journal

A case of life-threatening cardiac arrhythmia associated with magnesium deficiency is described. The patient had no history of any cardiac disease, was not taking any medication and had no other accompanying electrolyte disorder. His arrhythmia was refractory to conventional treatment but responded to parenteral magnesium therapy. The role of hypomagnesemia in the predisposition to cardiac arrhythmia is discussed. To our knowledge, there are only two well-documented cases of ventricular irritability which responded to magnesium as the sole treatment. As awareness of such a relationshp increases and magnesium determinations become more available, this entity may be more commonly recognized, and the …

Dissecting Aneurysm Of Aorta Complicating Coarctation Of The Aorta: Case Report And Brief Literature Review, Remigio Garcia, Julius M. Ohorodnik, Donald J. Magilligan Jr.

Henry Ford Hospital Medical Journal

The incidence of dissecting thoracic aorta aneurysm complicating coarctation of the aorta ranges from 1.7 to 23% in large series of coarctation of the aorta reported. In a review of 95 cases of dissection of the aorta, we found only one case with associated coarctation of the aorta. The presence of this anomaly, although rare, should be suspected and searched for in younger patients with dissection, in view of the surgical implications at the time of correction.

Use Of The Intraocular Lens In The Aphakic Eye - Part 1: The Anterior Chamber Intraocular Lens, Philip C. Hessburg

Henry Ford Hospital Medical Journal

Th;s paper reviews some reasons why many ophthalmic surgeons do not implant intraocular lenses. It presents some parameters of a theoretically "ideal" lens, some of the disadvantages and advantages of the currently available anterior chamber intraocular lenses, and lastly, it offers designs for a new anterior chamber intraocular lens. While preserving the advantages of currently available anterior chamber intraocular lenses, the new designs may have certain advantages. Currently under investigation, the new lenses may be available for use in man within the next year.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Laboratory Animals And Alternatives In The 80'S, Andrew N. Rowan

Laboratory Experiments Collection

No abstract provided.

Live Animals In Car Crash Studies, Nancy Heneson

Experimentation Collection

The scientific rationale for using live animals in car crash studies proceeds from the argument that comparative biomedical and biomechanical data are needed to develop an instrumented dummy, or anthropomorphic test device, which will provide reliable, reproducible information for designing safe cars. The animal studies are thus not really ends in themselves, i.e., they do not supply data which can be readily applied to real situations. Instead, they contribute to a pool of information which is supposed to lead to the perfecting of an experimental subject (the instrumented dummy) which will eventually render the further use of Iive animals unnecessary.

Nsmr: Its Image, Direction And Future, J. Russell Lindsey

Experimentation Collection

The point I wish to emphasize is that NSMR, like all of its predecessors representing the scientific community, has consistently maintained a defensive posture while claiming that a// practices of animal use and care within the biomedical community have been "lily white." In my judgment, this has been a major tactical error because abuses of freedoms to use animals in research too frequently have been and continue to be common knowledge (e.g., Science, Editorial, 1976). NSMR's complete unwillingness to face up to these realities and torespond positively to the public's legitimate concerns has led to the inevitable loss of credibility …

Amputation Of Vibrissae In Show Dogs, Thomas E. Mcgill

Veterinary Science and Medicine Collection

Dogs of many different breeds competing in the show-ring are routinely subjected to amputation of the vibrissae, organs that are commonly and incorrectly called "whiskers." This procedure is thought to give the animal's head a cleaner look, which in turn supposedly increases its chances of winning. There are several tricks involved in "whisker trimming" since the animals can retract each vibrissae at least one-quarter inch. Furthermore, they often object strenuously to the operation.

Ethology And Laboratory Animal Welfare, James A. Cohen

Laboratory Experiments Collection

At its annual conference, held this June at Colorado State University in Fort Collins, the Animal Behavior Society (ABS) passed a resolution opposing HR 4805, a bill which would establish a National Center for Alternative Research to develop and coordinate alternative methods of research and testing which do not involve the use of live animals. The ABS, which represents some 1750 North American animal behavior researchers, took issue with the bill on the grounds that: a) it discourages replication of previously-obtained results, b) there are currently no satisfactory substitutes for live animals in behavioral research, c) it would complicate and …

Pain-Infliction In Animal Research, Dorothy Tennov

Experimentation Collection

A summary of research outlining the main sources of pain and stress to animals in laboratories provides the background for the results of a survey conducted by the author on how students feel about experimentation involving animals. The psychological aspects of student reaction to animal experimentation are examined. The conclusion outlines specific recommendations on ways to minimize pain and discomfort of laboratory animals.

Geophysical Surveys For Buried Waste Detection At The Idaho National Engineering Laboratory, U.S. Department Of Energy

All U.S. Government Documents (Utah Regional Depository)

This report describes a series of geophysical surveys performed at the Idaho National Engineering Laboratory (INEL). The main purpose of the surveys was to evaluate techniques, principally ground-penetrating radar, for detecting and mapping radioactive wastes buried in shallow trenches and pits.

Screening Of Clovers For Resistance To Clover Scorch, D. L. Chatel

Experimental Summaries - Plant Research

Clover Scorch (Jointly with Dr C.M. Francis). One thousand four hundred and seventy six legumes were screened in the field at the Denmark Research Station for susceptibility to clover scorch. They comprised 1440 subterranean clovers, eight other Trifoliums, two medics and 26 serradellas. The clovers from Australia gave interesting results. Thirty four of them were selections of Seaton Park, chosen by R.C. Rossiter and W. J. Collins on the basis of their variation. They did not differ in their reaction to clover scorch; all gave rating of 9. Twenty-six lines of Woogenellup from W.A. and 12 of Woogenellup and Morrar …

Legume Diseases, P Mcr Wood

Experimental Summaries - Plant Research

Lupin root disorder. Resistance to lupins to Phomopsis leptostromiformis (Fungal ratings by P. McR. Wood and F.M. O'Donnell, data compiled by J. Hamblin, Plant Production Division) Phomopsis levels on any particular genotype are influenced by environment. Therefore material selected for Phomopsis resistance is done so on its being better than average over all sites. Data for the Plant Breeders' S2-l trial at Avondale (ARS), Badgingarra (BRS), Chapman (CRS), Esperance (ERS) and Mt. Barker (MTRS) are shown in Table 3.

Effects Of Organic Compounds On Amphibian Reproduction, Wesley J. Birge, Jeffrey A. Black, Robert A. Kuehne

KWRRI Research Reports

Aquatic toxicity tests were conducted with atrazine, carbon tetrachloride, chloroform, methylene chloride, trisodium nitrilotriacetic acid (NTA), and phenol. Each compound was administered to developmental stages of three to five amphibian species. Exposure was initiated at fertilization and maintained through 4 days posthatching. Test responses included lethality and teratogenesis. Different amphibian species exhibited varying degrees of tolerance to the selected compounds. Greatest tolerance usually was observed for the more broadly adapted semi-aquatic and terrestrial species (e.g., Bufo americanus, Bufo fowleri). The more sensitive amphibians usually included those species which normally are restricted to aquatic or moist habitats (e.g., Rana …

The Effect Of Walk Or Jog Recovery From Anaerobic Work On Blood Lactate Levels And Subsequent Two-Minute Run Performance, Rick Alan Livesey

Masters Theses

The purpose of the study was to investigate the effects of a walk or jog recovery on two-minute run performances and the concentrations of blood lactate.

Eight highly trained male subjects were selected from the Eastern Illinois University Track Team. The test procedure consisted of two, maximal two-minute runs on the track for distance, separated by a 30-minute recovery. The recovery consisted of a walk at 20-minutes per mile pace or a jog at 7½ to 8 minutes per mile pace. Venous blood samples were drawn three minutes after the first run, two minutes prior to the second run, and …

Comparative Effects Of Two Avoidance Paradigms Upon Ethanol Self-Selection, Richard O. Shellenberger Ii

Masters Theses

Twelve adult male rats were given free access to a two bottle free-selection of tap water or a 10% ethanol/tap water solution in the home cage for a period of 140 consecutive days with the alcohol consumption data in the form of mg absolute ETOH/g subject weight collected daily. This study incorporated three stages. Phase I was a 40 day period of alcohol acclimation with alcohol consumption during the second 20 days constituting the baseline consumption rate. Mean baseline alcohol consumption was used to block subjects into three groups. The second phase of the study consisted of an 80 day …

1980 Beef Cattle Report, Leo E. Lucas

Nebraska Beef Cattle Reports

Weighing steers three consecutive days at the beginning and end of the trial reduced variation and increased the probability of detecting a difference in daily gain and gain/protein ratios between treatments when compared to a standard weighing method (once at the beginning and once at the end of the trial). Regressing 1 initial, 1 final and 11 weekly weights also decreased variation and increased the probability of detecting treatment differences compared to the standard method, but was more variable than using three weights at the beginning and end of the trial.

Young, growing steers and lambs supplemented with natural protein …

Effects Of Fixed Interval And Continuous Biofeedback Reinforcement On Emg Frontalis Muscle Activity, Kathleen I. Twinem

University of the Pacific Theses and Dissertations

The effects of continuous vs. intermittent reinforcement using electromyographic (EMG) feedback as the reinforcer were compared in reducing frontalis muscle activity. Fourteen subjects were chosen from a group of 30 students who had expressed an interest in learning how to relax. Those students having the highest pre-experimental baseline scores were chosen. They were matched according to both those scores and sex and then randomly assigned to either a continuous biofeedback reinforcement group or a 30 sec. fixed interval biofeedback reinforcement group. The experiment consisted of nine sessions (three acquisition, two treatment, and four extinction) with integrated EMG activity from the …

End Matter, Vol. 3

Great Basin Naturalist Memoirs

No abstract provided.