Medicine and Health Sciences Commons^™

La Percepción Cromática Media La Respuesta A Estímulos Rojos, Verdes, Azules Y Amarillos En Niños De Escuela Primaria En México, Myrna Miriam Valera Mota, Jorge Bernal Hernández, Ilhuicamina Melina Ávila Lara, Enrique Jiménez Valencia, Mariana Guzmán Noriega

Ciencia y Tecnología para la Salud Visual y Ocular

Propósito: evaluamos las respuestas a estímulos (longitud de onda) de percepción cromática en el espectro visible en niños de una escuela primaria en el campo de Nezahualcoyotl, México. Materiales y métodos: se usó un software desarrollado ad hoc para medir cómo los niños perciben los colores azul, verde, amarillo y rojo. Las pruebas se hicieron de forma monocular y las respuestas fueron agrupadas con base en su semejanza según el índice de correlación de Pearson y el análisis de clúster por promedios no ponderados. Se aplicó una prueba chi-cuadrado a los grupos para ver las diferencias significativas. Resultados: los datos …

Tratamientos Tópicos Oculares Para El Segmento Anterior Y Uso De Fármacos Diagnósticos En Población Pediátrica, Adriana Camila Gayón Muñoz, Nancy Piedad Molina-Montoya

Ciencia y Tecnología para la Salud Visual y Ocular

En los niños, la prescripción de medicamentos para el diagnóstico y tratamiento de patologías de segmento anterior representa un gran reto para los profesionales de la salud, debido a que se requiere de un amplio conocimiento sobre el momento de prescribirlos y de ofrecer tratamientos efectivos, con mínimo riesgo de generar efectos adversos. Este trabajo tuvo como propósito referenciar aspectos que se deben tener en cuenta en la formulación de medicamentos tópicos oculares, para el diagnóstico y tratamiento de patologías oculares de segmento anterior, en niños menores de 12 años. Para esto, se adelantó una búsqueda y revisión documental, en …

Etiología Y Factores Asociados A Fototoxicidad Retinal, Angélica María Cristancho Chaparro, Diana V. Rey-Rodríguez

Ciencia y Tecnología para la Salud Visual y Ocular

Los efectos nocivos de la radiación solar en la piel y en la superficie ocular se conocen claramente; sin embargo, los daños fotoquímicos en la retina aún son motivo de investigación. Se ha documentado que incluso el tiempo reducido, único o recurrente de exposición a la radicación puede inducir cambios histológicos que afectan la calidad de la visión, desde alteraciones transitorias hasta maculopatías irreversibles. Pese a esto, existe limitada información sobre la prevalencia e incidencia de los casos relacionados a exposición lumínica ambiental u ocupacional. Esta investigación tuvo propósito identificar la etiología y factores asociados a fototoxicidad retinal adquirida y …

Efecto De Los Prismas Gemelos En La Atención, Postura Y Comportamiento En Niños Con Trastorno Del Espectro Autista (Tea), Elizabeth Casillas Casillas, Jaime Bernal Escalante, Sergio Ramírez González, Luis Héctor Salas Hernández, Raúl Arias Ulloa, José De Jesús Espinosa Galaviz, Luis Fernando Barba-Gallardo

Ciencia y Tecnología para la Salud Visual y Ocular

El trastorno del espectro autista (TEA) se caracteriza por una alteración generalizada del desarrollo cerebral, que afecta la socialización, comunicación, imaginación y reciprocidad emocional y se evidencia mediante conductas repetitivas e inusuales. El uso de prismas gemelos estimula una reorganización neurológica y provoca cambios en la percepción visual. El objetivo del presente artículo fue evaluar las habilidades visuales y determinar el efecto de los prismas gemelos en la atención, postura y comportamiento de los niños con TEA. Se elaboró un estudio de intervención con muestras pareadas antes-después; se incluyeron 20 niños con diagnóstico de TEA en edades de 4 a …

Manifestaciones Oculares Del Covid-19, Nancy Piedad Molina-Montoya

Ciencia y Tecnología para la Salud Visual y Ocular

No abstract provided.

Ventilation & Masks: Reducing Airborne Transmission Of Covid-19 In A Classroom, Eric A. Schiff

SyracuseCoE Research Brief Series

We've calculated the number of COVID-19 infections that will be spread from a single COVID-19 "superspreader" to students and teachers in a classroom shared for 4 hours in different ventilation and masking conditions.

A Strategy To Predict The Global Warming Gas From Stock Farming —Potential Scaling Law Of The Released Methane From Livestock—, Toshiaki Nakashima, Tsuneyoshi Matsuoka, Yuji Nakamura

Progress in Scale Modeling, an International Journal

This work examines a scaling approach to predict the amount of methane released from the daily activity of livestock on farms. The subject animals are ruminants, i.e. having rumen or a ruminant stomach, that generates methane through digestion processes via several microbial fermentation steps. The produced methane is mixed into their breathing and released into the atmosphere. Existing data on methane released from various kinds of ruminant livestock were correlated as a power function of an animal’s weight, with an exponent near 0.92. This value is larger than a value of 0.75 which was related to the general metabolism rates …

Circus In Motion: A Multimodal Exergame Supporting Vestibular Therapy For Children With Autism, Oscar Peña, Franceli L. Cibrian, Monica Tentori

Engineering Faculty Articles and Research

Exergames are serious games that involve physical exertion and are thought of as a form of exercise by using novel input models. Exergames are promising in improving the vestibular differences of children with autism but often lack of adaptation mechanisms that adjust the difficulty level of the exergame. In this paper, we present the design and development of Circus in Motion, a multimodal exergame supporting children with autism with the practice of non-locomotor movements. We describe how the data from a 3D depth camera enables the tracking of non-locomotor movements allowing children to naturally interact with the exergame . A …

Pathophysiology And Proteogenomics Of Post-Infectious And Post-Hemorrhagic Hydrocephalus In Infants, Albert M. Isaacs

Arts & Sciences Electronic Theses and Dissertations

Post-infectious (PIH) and post-hemorrhagic (PHH) hydrocephalus occur as sequalae of neonatal sepsis or intraventricular hemorrhage (IVH) of prematurity, respectively. Together, PIH and PHH represent the most common form of infantile hydrocephalus, the most common indication for neurosurgery in children globally, and the leading cause of neurological morbidity and mortality worldwide. The lack of understanding of the pathophysiology of PIH and PHH, particularly with regards to the host central nervous system response to the antecedent infection and hemorrhage, perturbation of differentiating neural stems in the ventricular (VZ) and subventricular (SVZ) zones, and damage to periventricular white matter (PVWM) tracts carrying sensorimotor …

Effect Of Nanofiller Coating And Loading On Facial Elastomer Physical Properties, Rahmi K. Aulia

Theses & Dissertations

Current materials used for facial prostheses are far from being desirable, and improved properties with “skin-like” feel are needed. This study evaluates property changes induced by sequential additions of uncoated and hydrophobic-coated nano-SiO₂ to polydimethylsiloxane (PDMS) and compares them with those measured for conventional submicron SiO₂-filled materials. Each filler type was sequentially added to vinyl-terminated PDMS at 0%, 0.5%, 5%, 10%, and 15% by weight. Tensile, tear, Durometer hardness, translucency and viscoelastic properties were evaluated, with hardness and translucency also evaluated following 3000 hours of outdoor weathering. Results demonstrated that 15% coated nano-SiO₂-filled PDMS materials …

Ronald E. Mcnair Scholars Program Profiles And Abstracts 2020, Mcnair Scholars Program

McNair Symposium

This is the complete event program and provides presentation abstracts and biographies of McNair scholars and their mentors.

A Biomechanical Investigation Into The Effect Of Experimental Design On Wrist Biomechanics And Contact Mechanics, Clare E. Padmore

Electronic Thesis and Dissertation Repository

The wrist is one of the most commonly injured joints, and injury can have serious sequelae if pathological healing ensues. Strides have been made to understand normal and pathological wrist biomechanics using experimental approaches, which has contributed to improved patient care. The present work advances our understanding of the influence of experimental techniques and joint motion measurement techniques on in-vitro wrist biomechanical cadaveric studies, and applies the knowledge learned to a common clinical entity of scapholunate insufficiency.

First, the relative contributions of the carpal rows to wrist motion were assessed, in addition to the identification of limitations of current biomechanical …

Admittance Method For Estimating Local Field Potentials Generated In A Multi-Scale Neuron Model Of The Hippocampus, Clayton S. Bingham, Javad Paknahad, Christopher Bc Girard, Kyle Loizos, Jean-Marie C. Bouteiller, Dong Song, Gianluca Lazzi, Theodore W. Berger

Engineering Faculty Articles and Research

Significant progress has been made toward model-based prediction of neral tissue activation in response to extracellular electrical stimulation, but challenges remain in the accurate and efficient estimation of distributed local field potentials (LFP). Analytical methods of estimating electric fields are a first-order approximation that may be suitable for model validation, but they are computationally expensive and cannot accurately capture boundary conditions in heterogeneous tissue. While there are many appropriate numerical methods of solving electric fields in neural tissue models, there isn't an established standard for mesh geometry nor a well-known rule for handling any mismatch in spatial resolution. Moreover, the …

Nanoceria Distribution And Effects Are Mouse-Strain Dependent, Robert A. Yokel, Michael T. Tseng, D. Allan Butterfield, Matthew L. Hancock, Eric A. Grulke, Jason M. Unrine, Arnold J. Stromberg, Alan K. Dozier, Uschi M. Graham

Pharmaceutical Sciences Faculty Publications

Prior studies showed nanoparticle clearance was different in C57BL/6 versus BALB/c mice, strains prone to Th1 and Th2 immune responses, respectively. Objective: Assess nanoceria (cerium oxide, CeO₂ nanoparticle) uptake time course and organ distribution, cellular and oxidative stress, and bioprocessing as a function of mouse strain. Methods: C57BL/6 and BALB/c female mice were i.p. injected with 10 mg/kg nanoceria or vehicle and terminated 0.5 to 24 h later. Organs were collected for cerium analysis; light and electron microscopy with elemental mapping; and protein carbonyl, IL-1β, and caspase-1 determination. Results: Peripheral organ cerium significantly increased, generally more …

Using Natural Language Processing And Sentiment Analysis To Augment Traditional User-Centered Design: Development And Usability Study, Curtis L. Petersen, Ryan Halter, David Kotz, Lorie Loeb, Summer B. Cook, Dawna M. Pidgeon, Brock Christensen, John A. Batsis

Dartmouth Scholarship

Background: Sarcopenia, defined as the age-associated loss of muscle mass and strength, can be effectively mitigated through resistance-based physical activity. With compliance at approximately 40% for home-based exercise prescriptions, implementing a remote sensing system would help patients and clinicians to better understand treatment progress and increase compliance. The inclusion of end users in the development of mobile apps for remote-sensing systems can ensure that they are both user friendly and facilitate compliance. With advancements in natural language processing (NLP), there is potential for these methods to be used with data collected through the user-centered design process.

Objective: This study aims …

Decellularization Of Porcine Cartilage Promotes Chondrogenic Differentiation Of Human Chondrocytes, Roxanne Nicole Stone

Boise State University Theses and Dissertations

Knee osteoarthritis (knee OA) is the most common type of osteoarthritis (OA) and accounts for 70% of arthritis-related hospital admissions and 23% of clinical visits. Major limitations in both the current non-surgical and surgical methods are that they only relieve pain and show no evidence for restoring natural tissue anatomy. Leaders in the field propose that a stem cell treatment approach holds promise for the regeneration of a greater proportion of hyaline-like tissue at the repair site. (Cross et al., 2014; Escobar Ivirico, Bhattacharjee, Kuyinu, Nair, & Laurencin, 2017; Helmick et al., 2008; Toh, Foldager, Pei, & Hui, 2014).

It …

Resilience In Nonmetropolitan Nebraska: Capacity To Overcome Disasters And Hardships. 2020 Nebraska Rural Poll Results, Rebecca Vogt, Cheryl Burkhart-Kriesel, Brad Lubben, L.J. Mcelravy, Timothy Meyer, Steve Schulz, Jason L. Weigle

Rural Futures Institute: Publications

The definition of resilience is the capacity to recover quickly from difficulties. Synonyms include toughness, perseverance and grit. Last spring’s severe weather events and this year’s ongoing COVID-19 pandemic are likely testing the resilience of rural Nebraskans. Given that, how do rural Nebraskans rate their communities on dimensions that measure their resiliency? How confident are they that the federal government or local emergency management authorities can contain infectious disease outbreaks? How do they rate their ability to help their community handle adversities? How prepared are rural Nebraskans to deal with financial emergencies? This paper provides a detailed analysis of these …

Methods To Investigate Hyperthermia Induced By Tumor Treating Fields, Ruchi Singh

Dissertations & Theses (Open Access)

Tumor Treating Fields (TTFields) are an antineoplastic treatment delivered via application of alternating electric fields using insulated transducer arrays placed directly on the skin in the region surrounding the tumor. TTF’s is a non-invasive application of low-intensity (1-3 V/cm), intermediate-frequency (100-500 kHz) alternating electric fields. The predominant mechanism by which TTFields are thought to kill tumor cells is the disruption of mitosis through the depolymerization of microtubules and interruption of the spindle structure leading to mitotic catastrophe and the formation of non-viable daughter cells. Tumor Treating fields do not stimulate nerves and muscle because of their high frequency, and do …

A Core Reference Hierarchical Primitive Ontology For Electronic Medical Records Semantics Interoperability, Ziniya Zahedi

Engineering Management & Systems Engineering Theses & Dissertations

Currently, electronic medical records (EMR) cannot be exchanged among hospitals, clinics, laboratories, pharmacies, and insurance providers or made available to patients outside of local networks. Hospital, laboratory, pharmacy, and insurance provider legacy databases can share medical data within a respective network and limited data with patients. The lack of interoperability has its roots in the historical development of electronic medical records. Two issues contribute to interoperability failure. The first is that legacy medical record databases and expert systems were designed with semantics that support only internal information exchange. The second is ontological commitment to the semantics of a particular knowledge …

Machine Learning Approaches For Fracture Risk Assessment: A Comparative Analysis Of Genomic And Phenotypic Data In 5130 Older Men, Qing Wu, Fatma Nasoz, Jongyun Jung, Bibek Bhattarai, Mira V. Han

Public Health Faculty Publications

The study aims were to develop fracture prediction models by using machine learning approaches and genomic data, as well as to identify the best modeling approach for fracture prediction. The genomic data of Osteoporotic Fractures in Men, cohort Study (n = 5130), were analyzed. After a comprehensive genotype imputation, genetic risk score (GRS) was calculated from 1103 associated Single Nucleotide Polymorphisms for each participant. Data were normalized and split into a training set (80%) and a validation set (20%) for analysis. Random forest, gradient boosting, neural network, and logistic regression were used to develop prediction models for major osteoporotic fractures …

Face Mask Effects Of Co2, Heart Rate, Respiration Rate, And Oxygen Saturation On Instructor Pilots, Andrew R. Dattel, Nicola M. O'Toole, Guillermina Lopez, Kenneth P. Byrnes

Publications

The COVID-19 pandemic has required people to take new measures to mitigate the spread of the communicable virus. Guidelines from health organizations, government offices, and universities have been disseminated. Adherence to these guidelines cannot be more critical for flight training. This study explored the effects face masks had on CO2, heart rate, respiration rate, and oxygen saturation while wearing a face mask at an oxygen level simulated to 5,000 feet. Thirty-two instructor pilots (IP) volunteered to participate in the study. IPs spent 90 minutes in a normobaric chamber while wearing a cloth face mask or a paper face mask. Participants …

"A Comparison Of Variable Selection Methods Using Bootstrap Samples From Environmental Metal Mixture Data", Paul-Yvann Djamen

Mathematics & Statistics ETDs

In this thesis, I studied a newly developed variable selection method SODA, and three customarily used variable selection methods: LASSO, Elastic net, and Random forest for environmental mixture data. The motivating datasets have neuro-developmental status as responses and metal measurements and demographic variables as covariates. The challenges for variable selections include (1) many measured metal concentrations are highly correlated, (2) there are many possible ways of modeling interactions among the metals, (3) the relationships between the outcomes and explanatory variables are possibly nonlinear, (4) the signal to noise ratio in the real data may be low. To compare these methods …

Plasma And Serum Proteins Bound To Nanoceria: Insights Into Pathways By Which Nanoceria May Exert Its Beneficial And Deleterious Effects In Vivo, D. Allan Butterfield, Binghui Wang, Peng Wu, Sarita S. Hardas, Jason M. Unrine, Eric A. Grulke, Jian Cai, Jon B. Klein, William M. Pierce, Robert A. Yokel, Rukhsana Sultana

Chemistry Faculty Publications

Nanoceria (CeO2, cerium oxide nanoparticles) is proposed as a therapeutic for multiple disorders. In blood, nanoceria becomes protein-coated, changing its surface properties to yield a different presentation to cells. There is little information on the interaction of nanoceria with blood proteins. The current study is the first to report the proteomics identification of plasma and serum proteins adsorbed to nanoceria. The results identify a number of plasma and serum proteins interacting with nanoceria, proteins whose normal activities regulate numerous cell functions: antioxidant/detoxification, energy regulation, lipoproteins, signaling, complement, immune function, coagulation, iron homeostasis, proteolysis, inflammation, protein folding, protease inhibition, adhesion, protein/RNA …

Is It Safe For My Child’S Asthma?, Utkarshani Jaimini, Amit Sheth, Krishnaprasad Thirunarayan, Maninder Kalra, Marco Valtorta

Publications

kHealth-Asthma, a personalised digital healthcare framework is developed to address the above shortcomings by continuous monitoring of the child’s digital phenotype, indoor, and outdoor environmental data. The kHealth-Asthma study has recruited 140 children (ongoing) with an aim to complete recruitment of 150 children. The study period is either 1 month or 3 month depending on the choice of the study participant. kHealth-Asthma collects 29 multi-modal parameters leading to 1852 data points per patient per day (i.e. deployment: 1 month:1852*30=55,560 data points per patient and 3 month:1852*90=166,680 data points per patient). The digital phenotype collected using the kHealth-Asthma generates a Digital …

Olfaction Modulates Inter-Subject Correlation Of Neural Responses, Paul Deguzman, Anshul Jain, Matthias H. Tabert, Lucas C. Parra

Publications and Research

Odors can be powerful stimulants. It is well-established that odors provide strong cues for recall of locations, people and events. The effects of specific scents on other cognitive functions are less well-established. We hypothesized that scents with different odor qualities will have a different effect on attention. To assess attention, we used Inter-Subject Correlation of the EEG because this metric is strongly modulated by attentional engagement with natural audiovisual stimuli.We predicted that scents known to be “energizing” would increase Inter-Subject Correlation during watching of videos as compared to “calming” scents. In a first experiment, we confirmed this for eucalyptol and …

Neuromotor Control Of The Hand During Smartphone Manipulation, Prasanna Kumar Acharya

LSU Doctoral Dissertations

The primary focus of this dissertation was to understand the motor control strategy used by our neuromuscular system for the multi-layered motor tasks involved during smartphone manipulation. To understand this control strategy, we recorded the kinematics and multi-muscle activation pattern of the right limb during smartphone manipulation, including grasping with/out tapping, movement conditions (MCOND), and arm heights.

In the first study (chapter 2), we examined the neuromuscular control strategy of the upper limb during grasping with/out tapping executed with a smartphone by evaluating muscle-activation patterns of the upper limb during different movement conditions (MCOND). There was a change in muscle …

Β-Amyloid And Tau Drive Early Alzheimer's Disease Decline While Glucose Hypometabolism Drives Late Decline, Tyler C. Hammond, Xin Xing, Chris Wang, David Ma, Kwangsik Nho, Paul K. Crane, Fanny Elahi, David A. Ziegler, Gongbo Liang, Qiang Cheng, Lucille M. Yanckello, Nathan Jacobs, Ai-Ling Lin

Sanders-Brown Center on Aging Faculty Publications

Clinical trials focusing on therapeutic candidates that modify β-amyloid (Aβ) have repeatedly failed to treat Alzheimer’s disease (AD), suggesting that Aβ may not be the optimal target for treating AD. The evaluation of Aβ, tau, and neurodegenerative (A/T/N) biomarkers has been proposed for classifying AD. However, it remains unclear whether disturbances in each arm of the A/T/N framework contribute equally throughout the progression of AD. Here, using the random forest machine learning method to analyze participants in the Alzheimer’s Disease Neuroimaging Initiative dataset, we show that A/T/N biomarkers show varying importance in predicting AD development, with elevated biomarkers of Aβ …

Automatic Detection Of Dynamic And Static Activities Of The Older Adults Using A Wearable Sensor And Support Vector Machines, Jian Zhang, Rahul Soangra, Thurmon E. Lockhart

Physical Therapy Faculty Articles and Research

Although Support Vector Machines (SVM) are widely used for classifying human motion patterns, their application in the automatic recognition of dynamic and static activities of daily life in the healthy older adults is limited. Using a body mounted wireless inertial measurement unit (IMU), this paper explores the use of an SVM approach for classifying dynamic (walking) and static (sitting, standing and lying) activities of the older adults. Specifically, data formatting and feature extraction methods associated with IMU signals are discussed. To evaluate the performance of the SVM algorithm, the effects of two parameters involved in SVM algorithm—the soft margin constant …

Study Of Temperature Profile In Drying Process, Shaxnoza Abduvaxitovna Sultanova, Jasur Esirgapovich Safarov, Tojiniso Tursunboyevna Raxmanova

Chemical Technology, Control and Management

The article describes the simulation of the temperature field in a wide range of structural and operational parameters of the drying process. A qualitatively new representation of the temperature field profile in the chamber is revealed. As a result of the experiments, criteria were found for the unevenness of the temperature profiles on the pallets of the dispersion of the temperature of the material and the slope of the approximating line at fixed values of the average temperature of the substance. In the course of the work, an interrelation between the criteria of unevenness was revealed, which is clearly manifested …

It Governance For Balancing Evolveability And Standardization In Health Information System Implementation In Ethiopian Context, Birkinesh Lagebo, Birkinesh Lagebo, Mark Gaynor Prof., Temtim Assefa Dr

African Conference on Information Systems and Technology

Failing to balance standardization and evolveability in IS design and implementation process results sustainability failure which is common in developing country. IS research provides various IS design solution including layered modular architecture to address both evolveability and standardization simultaneously. However, this design solution requires appropriate IT governance mechanisms which lacks both theoretical and empirical explanation in IS research. The core of this research is understanding IT governance mechanism design that can balance standardization and evolveability in the course of IS design and implementation. The research uses the case of District Health Information System-2 (DHIS-2), layered modular architecture, design and implementation …