Medicine and Health Sciences Commons^™

The Relationship Between Meat Consumption And The Biological Determinants Of Cardiovascular Disease Risk, Fred E. Kollwitz

Loma Linda University Electronic Theses, Dissertations & Projects

Fasting blood samples were collected from 26 omnivore and 27 vegetarian men (35-60 years of age), who were not taking any medications and by self-assessment were in good health. The following analyses were done: glucose (Glu), glycohemoglobin (HBA1), total serum cholesterol (chole), high density lipoprotein-cholesterol (HDD, low density lipoprotein (LDL), very low density lipoprotein (VLDL), platelet factor four (PF4), and beta-thromboglobulin (BTG). In addition, the blood pressure (BP) was determined.

The systolic (p<0.001) and diastolic BP (p=0.016) were lower in the vegetarian subjects than in the omnivores. The serum total cholesterol levels were also lower in the vegetarian subjects compared to the omnivores (p<0.05). There was no significant difference in Glu, HBA1, LDL, VLDL, HDL, PF4, and BTG levels between the two groups.

Magnesium, Copper And Zinc Concentrations In Blood From Children With Diabetes Mellitus, Linda Lowers Jenkins

Chemistry & Biochemistry Theses & Dissertations

Trace element levels in blood from diabetic children were investigated and compared to control children. Plasma, erythrocyte, mononuclear and polymorphonuclear cells were analyzed for magnesium, copper, and zinc content. Leukocyte separation was performed by density gradient centrifugation on Ficoll-Hypaque, followed by washing steps to remove platelet contamination and hypotonic lysis to remove red cell contamination. Polarized Zeeman-effect atomic absorption spectroscopy was used for trace metal analysis.

Decreased plasma magnesium levels were observed in the diabetic children. This finding is well documented and probably due to increased urinary magnesium loss from glycosuria. Lymphocyte magnesium levels in the diabetic children were also …

Absence Of A Structural Basis For Intracellular Recognition And Differential Localization Of Nuclear And Plasma Membrane-Associated Forms Of Simian Virus 40 Large Tumor Antigen., Donald L. Jarvis, Charles N. Cole, Janet S. Butel

Dartmouth Scholarship

The simian virus 40 large tumor antigen (T-ag) is found in both the nuclei (nT-ag) and plasma membranes (mT-ag) of simian virus 40-infected or -transformed cells. It is not known how newly synthesized T-ag molecules are recognized, sorted, and transported to their ultimate subcellular destinations. One possibility is that these events depend upon structural differences between nT-ag and mT-ag. To test this possibility, we compared the structures of nT-ag and mT-ag from simian virus 40-infected cells. No differences between the two forms of T-ag were detected by migration in polyacrylamide gels, by Staphylococcus aureus V8 partial proteolytic mapping of methionine- …

Preventing Lupinosis With Phomopsis-Resistant Lupins, Jeremy G. Allen, W. A. Cowling

Journal of the Department of Agriculture, Western Australia, Series 4

Lupinosis is one of the major livestock siseases in Western Australia. It is caused by stock eating toxins produced by the fungus Phomopsis leptostromiformis which colonises the stems of dead lupin plants.

In 975, the Department of Agriculture started a breeding programme to develop Phompsis-resistant lupins to overcome or control lupinosis. In the previous issue of this Journal the results of small plot evaluations of new lines of Phompsis-resistant lupins developed in this programme were reported. This article describes the first trial involving grazing of Phompsis-resistant lupins.

Annual Ryegrass Toxicity Research Update, A G P Brown, P. Vogal

Journal of the Department of Agriculture, Western Australia, Series 4

Annual ryegrass toxicity (ARGT) is a complex disease that kills sheep and cattle grazing pastures which contain infected ryegrass. The disease results when a nematode (Anguina agrostis) and a batcerium (Corynebacterium sp.) invade annual ryegrass and cause the seed heads to become toxic as the grass dries off.

The bacterium produces a complex toxin of 18 glycolipid compounds or corynetoxins which have been found to be virtually identical to the antibiotic tunicamycin.

Accidents Types Des Monteurs De Lignes Du Secteur De La Construction (Annexe), Évelyne Kedl, Lucie Laflamme, Lyne Marinacci

Rapports de recherche scientifique

La première phase du projet dont il est ici question vise à résumer, en un nombre limité d’accidents types, les circonstances dans lesquelles les monteurs de lignes se blessent le plus souvent et les caractéristiques les plus courantes de leurs lésions. À cette fin, les fichiers "pairés" d’accidents des trois entrepreneurs participants et de la CESST ont servi à décrire 236 accidents en utilisant un total de 15 variables. Le traitement de ces données, rétrospectives, a conduit à la reconstruction de six classes d’accidents différentes les unes des autres.

Ces classes se distinguent d’abord par le genre de l’accident. Nos …

Accidents Types Des Monteurs De Lignes Du Secteur De La Construction, Évelyne Kedl, Lucie Laflamme, Lyne Marinacci

Rapports de recherche scientifique

La première phase du projet dont il est ici question vise à résumer, en un nombre limité d’accidents types, les circonstances dans lesquelles les monteurs de lignes se blessent le plus souvent et les caractéristiques les plus courantes de leurs lésions. À cette fin, les fichiers "pairés" d’accidents des trois entrepreneurs participants et de la CESST ont servi à décrire 236 accidents en utilisant un total de 15 variables. Le traitement de ces données, rétrospectives, a conduit à la reconstruction de six classes d’accidents différentes les unes des autres.

Ces classes se distinguent d’abord par le genre de l’accident. Nos …

Concentrations Of Uranium Isotopes In Uranium Millers' And Miners' Tissues, United States Nuclear Regulatory Commission

Health

The alpha-emitting isotopes of uranium and thorium were determined in the lungs of 14 former uranium miners and in soft tissues and bones of three miners and two millers. These radionuclides were also determined in soft tissues and bones of seven normal controls. The average concentrations in pCi/kg wet weight in 17 former miners' lungs are as follows: U-238, 75; U-234, 80; Th-230, 79. Concentrations of each nuclide ranged from 2 to 325 pCi/kg. The average ratio of U-238/U-234 ws 0.92, ranging from 0.64 to 1.06. The mean ratio of Th-230/U-234 was 1.04, ranging from 0.33 to 3.54. The near …

A Rapid Concentration And Identification Technique For Human Malaria Infections Using A Mouse Model, Donald D. Barton

Loma Linda University Electronic Theses, Dissertations & Projects

Red blood cells infected with malaria parasites experience a change in density making them lighter (less dense). This paper reports a new, rapid diagnostic technique using this change in density in the infected red blood cell. It is not only easy to use, but it is also compatible with the technological conditions found where the malaria problem is most acute - in many developing countries of the world. A small sample of blood drawn from a simple finger stick can be concentrated and examined microscopically for malaria parasites within 10 minutes. The thick film slide preparation, presently used, takes a …

The Relationship Of Vitamins B-6 And B-12 To Plasma Homocysteine Levels In Men At Low- And High-Risk For Coronary Heart Disease, Marlene E. Swift

Loma Linda University Electronic Theses, Dissertations & Projects

There is evidence that homocysteine may be a factor in increasing the risk of coronary heart disease (CHD). To explore this relationship further, we assessed the interrelation of dietary vitamins B-6, B-12 and folate, and plasma pyridoxal-5'-phosphate and vitamin B-12 with plasma free and protein-bound homocysteine levels. Fasting blood and three-day dietary records were obtained from nine men low-risk (LR) and five at high-risk (HR) for CHD. The HR mean systolic blood pressure, total cholesterol (TC), and TC/cholesterol ratios were significantly higher than LR levels. Groups were comparable by age, weight, height, skinfolds, exercise, and smoking history. No significant difference …

Identification Of Sequences In The Herpes Simplex Virus Thymidine Kinase Gene Required For Efficient Processing And Polyadenylation., Charles N. Cole, Terryl P. Stacy

Dartmouth Scholarship

The herpes simplex virus (HSV) type 1 thymidine kinase gene (tk) was resected from its 3' end with BAL 31 exonuclease. Two sets of plasmids were isolated that lacked information distal to the two copies of the hexanucleotide 5'-AATAAA-3' located at the 3' end of the HSV tk gene. The presence of a simian virus 40 origin of DNA replication in each plasmid facilitated analysis of patterns of transcription in transfected Cos-1 monkey cells. Transcription analyses were performed with an S1 nuclease protection assay. Efficient processing and polyadenylation at the normal site still occurred when all sequences more than 44 …

Cryptosporidiosis In The Immunosuppressed Mouse And In Cell Culture, Mercy Prabhu Das

Loma Linda University Electronic Theses, Dissertations & Projects

Cryptosporidiosis is a parasitic infection primarily of animals that has been recently recognized as an important disease in immunocompromised humans. Most cases to date have occurred in patients with acquired immunodeficiency syndrome (AIDS). Persons with abnormal humoral or cellular immune function, and even normal subjects, have also been affected.

To determine whether or not mice, when experimentally immunosuppressed, would develop cryptosporidiosis, a test was designed using the AKR/J strain. This strain was selected because, it was previously reported that it was the strain shown to respond most readily to the production of disease caused by the opportunistic protozoan, Pneumocystis carinii …

Psychosocial And Behavioral Characteristics Of Ischemic Heart Disease Patients: Their Measurement And Relationship To Adherence In An Intensive Nutrition Education Program, Lynn Caldwell

Loma Linda University Electronic Theses, Dissertations & Projects

Nonadherence to therapeutic regimens which necessitate major lifestyle change is recognized as one of the most serious problems in medical practice today. Attempts to prevent and control chronic disease, including the development and progression of cardiovascular disease, are only effective when recommendations to the patient are carried out. Few studies have systematically studied the relationship of psychosocial and behavioral factors to adherence outside the theoretical framework of a specific behavioral model; no study has done so with a carefully measured diet as the outcome variable in a controlled prospective clinical trial with patients suffering from cardiovascular disease.

This study, as …

Oral History Interview: Dr. Pat Tuckwiller, Pat Tuckwiller

0064: Marshall University Oral History Collection

Dr. Pat Tuckwiller was born on April 13, 1905, in Morgantown, West Virginia. He received his medical degree from Rush Medical College in Chicago, Illinois, in 1929 and began practicing internal medicine in Charleston, West Virginia, on April 1, 1932. Dr. Tuckwiller discusses making house calls in Kanawha County, West Virginia, and focuses on the most common illnesses he treated and the medicines and procedures he used. He also discusses the differences in medical practice from the 1930s to the 1980s. In the audio clip provided, Dr. Tuckwiller discusses the issue of venereal disease in West Virginia and focuses on …

The Federal Black Lung Program--The View From The Top, Robert L. Ramsey, Robert S. Habermann

West Virginia Law Review

No abstract provided.

A Survey Of Drench Resistance In Sheep Worms, J R. Edwards, R. Wroth, G. C. De Chaneet, R. B. Besier, J. Karlsson, P. W. Morcombe, D. Roberts, G. Dalton-Morgan

Journal of the Department of Agriculture, Western Australia, Series 4

Sheep worms which are resistant to chemical drenches have been detected with increasing freuency is Western Australia's south-western farming areas between 977 and 1980. These worms have anthelmintic resistance and such genetis resistance puts essential internal parasite control practices at risk.

This prompted veterinarians in the Esperance, Albany, Bunbury, Geraldton and Northam areas to survey farms to determine the prevalence of resistance to drenches and to define those sheep management practices which encourage its development.

This article describes the survey which was conducted to assess the extent of drench resistance, what causes its build-up and how it can be controlled …

'Dermo' Fleece Rot And Body Strike On Sheep, S G. Gherardi, S. S. Sutherland, N. Monzu

Journal of the Department of Agriculture, Western Australia, Series 4

Blowfly strike is one of the major problems confronting the sheep industry in Austrsalia, with an estimated totsalcost of control eceeding $100 million each year.

Sheep are susceptible to five types of strike: body, breach, poll, pizzle and wound. Body strike, is of greater economic importance because its sporadic occurence from year to year makes it difficult to predict and cintrol. Outbreaks of body strike after rain can affect large numbers of sheep and inflict severe production losses.

In eastern Australia fleece rot is generally considered to be the main predisposing factor to blowfly strike, but in Western Australia evidence …

Ua37/30/2 Wku Research Notecards - H Topics, Lowell Harrison

Faculty/Staff Personal Papers

Notecards created by Lowell Harrison while researching his book Western Kentucky University. The cards transcribed are for 108 topics beginning with H ranging from Hail Storm to Hundred Club.

Modification Of Sand Fly Biting Behavior By Leishmania Leads To Increased Parasite Transmission, Raymond Beach, Gabriel Kjilu, Johannis Leeuwenberg

Harold W. Manter Laboratory of Parasitology: Library Materials

To attempt rodent-sand fly-rodent transmission of Leishmania major, laboratory-reared Phlebotomus doboscqi were fed on L. major-infected mice and then refed on uninfected mice 21 days later. Flies which refed either probed 1–2 times and took a full blood meal in less than 10 minutes or probed 3 or more times and took little or no blood during a period of 15 minutes or more. When dissected, 7 of 8 flies which experienced difficulty in obtaining a blood meal had flagellates in their cibaria, an observation supporting the hypothesis that parasites in this part of the alimentary canal modify normal …

Namru-3 Translations Of Parasite Literature From Russian, French, Japanese, Etc. Into English (1929-1985) T1701-T1800, United States Naval Medical Research Unit Number Three, Cairo, Medical Zoology Department

United States Naval Medical Research Unit 3: Publications

T1701. TRANSLATION FROM RUSSIAN, OVEZMUKHAMMEDOV, A. and SAF'YANOVA, V. M. (1983), Occurrence of amastigotes of Leishmania gymnodactyli in the peripheral blood of Gymnodactylus caspius and Agama caucasica. Parazitologiya, Leningrad. 17(3):185-188.

T1702. TRANSLATION FROM RUSSIAN. YASTREBOV, V. K. and YURLOV, K. T. (1978). Possible arbovirus dissemination in western Siberia in connection with data on migrations and overwinterings of west Siberian birds. Dokl. Simp. Transkont. Svyazi Pereletn. Ptits Rol' v Rasp. Arbovirus. (Novosibirsk, July-August, 1976), pp. 167-172.

T1703. TRANSLATION FROM GERMAN. MOSKVIN, I. A. (1929). On the role of the tick Ornithodoros papillipes Bir. (Ixodoidea) in transmitting relapsing fever in Turkestan. Z. …

A Quantitative Study Of The Distinctive Proteins Of The Eosinophil: A Comparison Of Normals And Eosinophilic Patients, James M. Olson

Honors Theses

Eosinophils have long been associated with parasitic and allergic diseases. Methods of procurement and purification of eosinophils in the last ten years have allowed intensive investigation into their components, properties, functions, and mechanisms (Gleich et al, 1982). The goals of this project are to separate eosinophils in blood samples taken from patients with eosinophilia and from normals based on density over distontinuous Metrizamide gradients; to determine quantitatively the levels of the three distinctive proteins of the eosinophil, specifically MBP, EDN, and ECP; and to compare the levels of these proteins found in eosinophils of patients with eosinophilia to the amounts …

Influenza: Prevention And Therapy, William M. Valenti

Henry Ford Hospital Medical Journal

No abstract provided.

The Effect Of Dietary Alpha - Linolenic Acid On Apparent Risk Factors Of Cardiovascular Disease, Kelvin D. Lindbeck

Loma Linda University Electronic Theses, Dissertations & Projects

Eight healthy male lacto-ovo-vegetarian subjects averaging 28.0 ± 3.6 years of age (22 to 53 years) were fed a diet rich in α-linolenic acid (18:3 ω 3) for four weeks. Arterial blood pressure and body weight were recorded each week. Plasma 6-keto-prostaglandin F_1α (6-keto- PGF_1α ), thromboxane B₂ (TXB₂), total cholesterol, triglyceride, and total phospholipid fatty acid composition were analyzed at 0, 2 and 4 weeks.

Systolic blood pressure increased significantly between weeks 0 and 1 (106.5 ± 2.7 mmHg to 114.0 ± 3.7 mmHg; p < 0.003), but decreased to 107.3 t 2.6 mrHg (p < 0.02) at week 2. There was an insignificant increase in both systolic and diastolic blood pressures after four weeks. There was no significant change in either total cholesterol or triglyceride levels during the four weeks.

Plasma 6-keto-PGF_1α levels increased significantly from 60.13 ± …

Black Lung Benefits Amendments Of 1981: Transfer Of Special Claims Under Section 205, James B. Stoneking

West Virginia Law Review

No abstract provided.

Heterosexual And Homosexual Patients With The Acquired Immunodeficiency Syndrome: A Comparison Of Surveillance, Interview, And Laboratory Data, Mary Guinan, Pauline A. Thomas, Paul F. Pinksy, James T. Goodrich, Richard M. Selik, H W. Jaffe, H W. Haverkos, Gary Noble, J W. Curran

School of Public Health Faculty Research

Homosexual and heterosexual patients with the acquired immunodeficiency syndrome were compared by risk group. Race; diagnoses; history of sexually transmitted diseases, sexual behavior, and drug use; and socioeconomic indicators differed considerably among the risk groups, suggesting different risk factors for acquisition of the syndrome. Patients in the homosexual, intravenous drug user, and Haitian risk groups differed in their serologic response to cytomegalovirus and syphilis testing, presumably due to lifestyle-related exposures. Differences in the rate of recovery of cytomegalovirus, serum levels of IgA and IgG, and antibody titers to Epstein-Barr virus were noted among patients with different diagnoses. We conclude that …

The Bush Tick, R B. Besier

Journal of the Department of Agriculture, Western Australia, Series 4

A newly discovered livestock parasite has focused attention on farms in the Walpole district in the south-west of Western Australia. Ticks submitted to the Department of Agriculture in December 983 were identified as the bush tick, Haemaphysalis longicornis. An intensive campaign to locate areas of infestation and to limit spread was started in January 1984.

The bush tick is a pest of livestock in some areas of New South Wales and Queensland. It is important in a narrow coastal strip from Sydney to Brisbane where total summer rainfall can exceed 1000 mm. In this area heavy tick infestation causes …

Namru-3 Translations Of Parasite Literature From Russian, French, Japanese, Etc. Into English (1973-1984) T1801-T1900, United States Naval Medical Research Unit Number Three, Cairo, Medical Zoology Department

United States Naval Medical Research Unit 3: Publications

T1801. TRANSLATION FROM RUSSIAN. KOLOTVINOV, S. V. and MASLENNIKOV, V. A. (1980). Method for evaluating the functional activity of viral antigens. Zh. Mikrobiol., Moskva, 57(8): 58-61.

T1803. TRANSLATION FROM GERMAN. CAFLISH, U., TONZ, O., SCHAAD, U. B., AESCHLIMANN, A. and BURGDORFER, W. (1984). Tick-borne meningo-radiculitis – a spirochetosis. Schweiz. Med. Wschr., 114(18):630-634.

T1804. TRANSLATION FROM FRENCH. LEW, D. (1984). Fevers developing after travels – some unusual cases. Schweiz. Med. Wschr., 114(29):1029-1031.

T1805. TRANSLATION FROM RUSSIAN. L'VOV, D. K., ANDREEV, V. P., ISACHENKO, V. A., YAKHNO, M. A. ZAKSTEL'SKAYA, L. Ya., SOKOLOVA, N. N. and VASIL' EV, V. I. (1974). Detection …

The Psychological Intervention Of Group Therapy For Women Coping With Genital Herpes, Susan D. Ferguson

Dissertations and Theses

Three groups of women who had been diagnosed as having genital herpes completed a series of psychological assessments over the course of the four-month research period. One group received two-hour weekly group psychotherapy sessions for eight consecutive weeks as a mode of treatment intervention. Two control groups were used for efficacy of treatment comparison. One control group consisted of regular members of a local self-help chapter for herpes victims. The second control group was formed from those volunteers willing to participate, but who did not choose, or desire, any form of treatment, Outcome measures reflected a greater improvement in psychological …

A Study Of The Environmental Aspects Of Schistosomiasis In Libya, Abubaker I. Swehli

Dissertations

Schistosomiasis is a serious disease in humans. Two species of schistosome, Schistosoma mansoni and Schistosoma haematobium, organisms that cause the disease, parasitize humans in Libya. Schistosomes require aquatic snails in their life cycle. The purpose of this study was to investigate the environmental and the host relationships of the disease in the three regions of Libya where the disease is found. These relationships include:

1) Analyses of the physical-chemical characteristics of the aquatic habitat.

2) Collection of snails to determine: a) the kind of snail species and th e ir abundance; and b) the cercarial infestation rates.

3) Infection rates …

The Effect Of Orally Administered Butylated Hydroxytoluene On Herpes Simplex Keratitis, Donald Carson

Masters Theses & Specialist Projects

Some studies have reported in vitro inactivation of membrane enveloped viruses by Butylated hydroxytoluene (BHT). This study investigates the effect of orally administered BHT on primary infections of Herpes simplex virus (HSV) using rabbit corneas as the assay system.

Assigned levels of BHT were incorporated into the diet of New Zealand White rabbits with HSV-1 McKrae strain on the corneal surface of the eyes. The degree of infection was measured by a subjective assay. Rabbits receiving BHT in their diet consistently experienced lower levels of infection. The interpretation of this data is that orally administered BHT can be an effective …