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Articles 1411 - 1440 of 21716

Full-Text Articles in Medicine and Health Sciences

Alcohol And Metabolic Stress Synergize To Dysregulate Mitochondrial Health And Lipid Metabolism; Evidence From A Hepatocyte Spheroid Model, Eden M. Gallegos, Kaitlin Couvillion, Drake Darden, Keishla Rodriguez-Graciani, Patricia E. Molina, Liz Simon Nov 2025

Alcohol And Metabolic Stress Synergize To Dysregulate Mitochondrial Health And Lipid Metabolism; Evidence From A Hepatocyte Spheroid Model, Eden M. Gallegos, Kaitlin Couvillion, Drake Darden, Keishla Rodriguez-Graciani, Patricia E. Molina, Liz Simon

School of Graduate Studies Faculty Publications

Metabolic dysfunction-associated steatotic liver disease and alcohol-associated liver disease frequently co-occur, manifesting as MetALD. Understanding the hepatocyte-specific effects of alcohol and metabolic stressors is critical to uncovering mechanisms of synergistic injury. This study evaluated the individual and combined effects of ethanol, sugars, and saturated/monounsaturated fats on hepatocyte lipid metabolism, oxidative stress, and mitochondrial function using a 3D human HepaRG spheroid model. HepaRG spheroids were treated with ethanol (50 mm), sugar (glucose and fructose), and fatty acids alone or in combination for 10 d. The combination of ethanol (E) and metabolic (sugar and fat, SF) stressors (ESF) synergistically increased triglyceride content …


Losing Focus In The Age Of Tik Tok: Clinical Evidence For Policy Action On Social Media Use, Megan Conefrey, Robert Griffin Nov 2025

Losing Focus In The Age Of Tik Tok: Clinical Evidence For Policy Action On Social Media Use, Megan Conefrey, Robert Griffin

SURE Journal: Science Undergraduate Research Experience Journal

No abstract provided.


Tracking Livestock Heart Rate & Location Using Long-Range Radio Networks. An Immediate Solution For Farms Without Reliable Wi-Fi, Dermott Harkin, Martin Bradley Nov 2025

Tracking Livestock Heart Rate & Location Using Long-Range Radio Networks. An Immediate Solution For Farms Without Reliable Wi-Fi, Dermott Harkin, Martin Bradley

SURE Journal: Science Undergraduate Research Experience Journal

No abstract provided.


Voices Matter: Tackling Accentism In Ireland. A Study Addressing Accent-Based Discrimination Awareness In Education, Sadhbh Reddington, Victoria Graham, Holly Jordan, Mairead Moriarty Nov 2025

Voices Matter: Tackling Accentism In Ireland. A Study Addressing Accent-Based Discrimination Awareness In Education, Sadhbh Reddington, Victoria Graham, Holly Jordan, Mairead Moriarty

SURE Journal: Science Undergraduate Research Experience Journal

No abstract provided.


Income Inequality And Attitudes Towards Immigrants – How Increased Inequality Drives Division, Niamh Anderson, Vincent O'Sullivan Nov 2025

Income Inequality And Attitudes Towards Immigrants – How Increased Inequality Drives Division, Niamh Anderson, Vincent O'Sullivan

SURE Journal: Science Undergraduate Research Experience Journal

No abstract provided.


Supporting Single Parents: How Loneliness And Self-Stigma Can Impact Single Parents And Their Quality Of Life, Alana Powell, David Mothersill Nov 2025

Supporting Single Parents: How Loneliness And Self-Stigma Can Impact Single Parents And Their Quality Of Life, Alana Powell, David Mothersill

SURE Journal: Science Undergraduate Research Experience Journal

No abstract provided.


Unheard And Underserved: Exploring Support For Male Victims Of Partner Abuse, Michael Keenan, Colletta Dalikeni Nov 2025

Unheard And Underserved: Exploring Support For Male Victims Of Partner Abuse, Michael Keenan, Colletta Dalikeni

SURE Journal: Science Undergraduate Research Experience Journal

No abstract provided.


Ireland Blossoms Through Multiculturalism - Designing For Community Connection, Julia Kuczera, Shirley Casey, Hilary Kenna Nov 2025

Ireland Blossoms Through Multiculturalism - Designing For Community Connection, Julia Kuczera, Shirley Casey, Hilary Kenna

SURE Journal: Science Undergraduate Research Experience Journal

No abstract provided.


Assessing Demand And Simulating Feasibility For Commuter Rail In Lagging Regional Areas. Case Study: Sligo, Holly Briere-Edney, Brian Mccann Nov 2025

Assessing Demand And Simulating Feasibility For Commuter Rail In Lagging Regional Areas. Case Study: Sligo, Holly Briere-Edney, Brian Mccann

SURE Journal: Science Undergraduate Research Experience Journal

No abstract provided.


Ireland's Infrastructure: From Delays To Deliveries!, Conor Barnett, Keren Goodman Nov 2025

Ireland's Infrastructure: From Delays To Deliveries!, Conor Barnett, Keren Goodman

SURE Journal: Science Undergraduate Research Experience Journal

No abstract provided.


A Fast-Track Way To Identify Derelict And Vacant Homes For Refurbishment, Dylan O'Donnell, Enda Dunican Nov 2025

A Fast-Track Way To Identify Derelict And Vacant Homes For Refurbishment, Dylan O'Donnell, Enda Dunican

SURE Journal: Science Undergraduate Research Experience Journal

No abstract provided.


Making Buildings Smarter And More Sustainable With Ai, Anthony Lowe, Martin Klepal Nov 2025

Making Buildings Smarter And More Sustainable With Ai, Anthony Lowe, Martin Klepal

SURE Journal: Science Undergraduate Research Experience Journal

No abstract provided.


Solving The Bed Crisis - Predicting 30-Day Hospital Readmissions In Elderly Patients Using Ai, Mark Mckeon, Thoa Pham Nov 2025

Solving The Bed Crisis - Predicting 30-Day Hospital Readmissions In Elderly Patients Using Ai, Mark Mckeon, Thoa Pham

SURE Journal: Science Undergraduate Research Experience Journal

No abstract provided.


The Impact Of Chronic Pain On Income And Employment, Jordan Vaarsi, Amber Jolly, Karim S. Ladha Nov 2025

The Impact Of Chronic Pain On Income And Employment, Jordan Vaarsi, Amber Jolly, Karim S. Ladha

SURE Journal: Science Undergraduate Research Experience Journal

No abstract provided.


Living The Life: A Community Approach To Men’S Health And Longevity, Paul Anders, Aisling Mcgrath Nov 2025

Living The Life: A Community Approach To Men’S Health And Longevity, Paul Anders, Aisling Mcgrath

SURE Journal: Science Undergraduate Research Experience Journal

No abstract provided.


When Care Can’T Move Forward – The Human And Social Cost Of Freezing Of Gait In Parkinson’S Disease, Padraig Cronin, Lucy M. Collins, Aideen M. Sullivan Nov 2025

When Care Can’T Move Forward – The Human And Social Cost Of Freezing Of Gait In Parkinson’S Disease, Padraig Cronin, Lucy M. Collins, Aideen M. Sullivan

SURE Journal: Science Undergraduate Research Experience Journal

No abstract provided.


Sticky Genes: Can Repeated Dna Sequences Trigger Motor Neurone Disease?, Guste Venslovaite, Russell Mclaughlin Nov 2025

Sticky Genes: Can Repeated Dna Sequences Trigger Motor Neurone Disease?, Guste Venslovaite, Russell Mclaughlin

SURE Journal: Science Undergraduate Research Experience Journal

No abstract provided.


Life Under Pressure: How Doubling The Genome Affects The Memory Of Environmental Stress In Worms, Aisling Phelan, Emma Bazzani, Clément Verdier, Laetitia Chauve, Aoife Mclysaght Nov 2025

Life Under Pressure: How Doubling The Genome Affects The Memory Of Environmental Stress In Worms, Aisling Phelan, Emma Bazzani, Clément Verdier, Laetitia Chauve, Aoife Mclysaght

SURE Journal: Science Undergraduate Research Experience Journal

No abstract provided.


Pause For Policy - The Cognitive Cost Of Cannabis Use In Adolescence, Michael O'Connor, Linda Kelly, Emma O'Hora, Claire O'Doherty, Ciaran Brown, An Hsu, Sahar Riaz, Frank Crosson, Darren Roddy, Mary Cannon Nov 2025

Pause For Policy - The Cognitive Cost Of Cannabis Use In Adolescence, Michael O'Connor, Linda Kelly, Emma O'Hora, Claire O'Doherty, Ciaran Brown, An Hsu, Sahar Riaz, Frank Crosson, Darren Roddy, Mary Cannon

SURE Journal: Science Undergraduate Research Experience Journal

No abstract provided.


From Recognition To Action: Advancing Nutrition Care In Irish Healthcare, Aoife Gillane, Sarah Donovan, Lisa Ryan Nov 2025

From Recognition To Action: Advancing Nutrition Care In Irish Healthcare, Aoife Gillane, Sarah Donovan, Lisa Ryan

SURE Journal: Science Undergraduate Research Experience Journal

No abstract provided.


The Future Of Metabolic Health: A Needle-Free Alternative For Blood Sugar Monitoring, Conor Cleary, Martin Bradley, Christopher Crosson, John Wade Nov 2025

The Future Of Metabolic Health: A Needle-Free Alternative For Blood Sugar Monitoring, Conor Cleary, Martin Bradley, Christopher Crosson, John Wade

SURE Journal: Science Undergraduate Research Experience Journal

No abstract provided.


Transforming Plastic For A Sustainable Planet: Next-Generation Materials That Biodegrade Naturally, Kristof Racz, Clement Higginbotham Nov 2025

Transforming Plastic For A Sustainable Planet: Next-Generation Materials That Biodegrade Naturally, Kristof Racz, Clement Higginbotham

SURE Journal: Science Undergraduate Research Experience Journal

No abstract provided.


The Dock Beetle: Reducing Costs And Pesticides In Irish Agriculture, Bianca Araujo, Daniel P. Fitzpatrick Nov 2025

The Dock Beetle: Reducing Costs And Pesticides In Irish Agriculture, Bianca Araujo, Daniel P. Fitzpatrick

SURE Journal: Science Undergraduate Research Experience Journal

No abstract provided.


Implementation Of The Nature Restoration Law In The Eu - Pros, Cons And Impossibilities, Emma Mcdonagh, Liam Sunner Nov 2025

Implementation Of The Nature Restoration Law In The Eu - Pros, Cons And Impossibilities, Emma Mcdonagh, Liam Sunner

SURE Journal: Science Undergraduate Research Experience Journal

No abstract provided.


Ireland’S Energy Transition: Unlocking The Potential Of Offshore Renewables, Caoimhe O'Hare, Madjid Karimirad, Gautam Baruah Nov 2025

Ireland’S Energy Transition: Unlocking The Potential Of Offshore Renewables, Caoimhe O'Hare, Madjid Karimirad, Gautam Baruah

SURE Journal: Science Undergraduate Research Experience Journal

No abstract provided.


From Conflict To Connection: Educators Leading The Shift Towards Restorative Practices (Rp) In Deis Primary Schools, Ellen Slattery, Clara Hoyne Nov 2025

From Conflict To Connection: Educators Leading The Shift Towards Restorative Practices (Rp) In Deis Primary Schools, Ellen Slattery, Clara Hoyne

SURE Journal: Science Undergraduate Research Experience Journal

No abstract provided.


Bridging The Gap From Preschool To Primary: From Policy To Practice, Aimee O'Connor, Cóilín O’ Braonáin Nov 2025

Bridging The Gap From Preschool To Primary: From Policy To Practice, Aimee O'Connor, Cóilín O’ Braonáin

SURE Journal: Science Undergraduate Research Experience Journal

No abstract provided.


Editorial, Anne M. Friel, Brigid Hooban, Therese Montgomery, Anne Marie O'Brien, Cormac Quigley, Edel Mcneela, Eva Campion, James Walshe, Sinead Loughran Nov 2025

Editorial, Anne M. Friel, Brigid Hooban, Therese Montgomery, Anne Marie O'Brien, Cormac Quigley, Edel Mcneela, Eva Campion, James Walshe, Sinead Loughran

SURE Journal: Science Undergraduate Research Experience Journal

No abstract provided.


Insecticide Resistance Profile In Nashville Culex Spp. Mosquito Populations, Ellie Sebaugh, Zachary Bement, Abelardo Moncayo, Darlene Panvini Nov 2025

Insecticide Resistance Profile In Nashville Culex Spp. Mosquito Populations, Ellie Sebaugh, Zachary Bement, Abelardo Moncayo, Darlene Panvini

Science University Research Symposium (SURS)

Mosquitoes may develop resistance to insecticides used by control programs, potentially increasing population density and the risk of mosquito-borne diseases. Culex spp. mosquitos are the primary vector of West Nile Virus (WNV), the leading cause of mosquito-borne disease in the United States and a reportable disease in Tennessee. Resistance profiles were constructed for two insecticides, permethrin and malathion, in a Culex spp. population from Nashville, Tennessee. Adult female mosquitoes were live-captured using gravid traps and tested using the Centers of Disease Control and Prevention (CDC) bioassay protocol to assess resistance or susceptibility. Three inhibitors were also included to identify metabolic …


Small For Gestational Age Subgroups Have Differential Morbidity, Growth, And Neurodevelopment At Age 2: The Interbio-21st Newborn Study, Aris T. Papageorghiou, María C. Restrepo-Ménde, Rose Mcgready, Fernando C. Barros, Francois Nosten, Shama Munim, Roseline Ochieng, Rachel Craik, Hellen C. Barsosio, Zulfiqar Ahmed Bhutta Nov 2025

Small For Gestational Age Subgroups Have Differential Morbidity, Growth, And Neurodevelopment At Age 2: The Interbio-21st Newborn Study, Aris T. Papageorghiou, María C. Restrepo-Ménde, Rose Mcgready, Fernando C. Barros, Francois Nosten, Shama Munim, Roseline Ochieng, Rachel Craik, Hellen C. Barsosio, Zulfiqar Ahmed Bhutta

Department of Obstetrics & Gynaecology

Background: Small for gestational age is a complex perinatal syndrome associated with increased neonatal morbidity, mortality, and impaired childhood growth and neurodevelopment. Current classifications rely primarily on birthweight, which does not capture the heterogeneity of the condition nor predict long-term health outcomes. Here we aim to identify and characterize distinct small for gestational age subgroups and assess their neonatal and early childhood health trajectories.
Objective: To refine the classification of small for gestational age by identifying subgroups based on maternal, fetal, and environmental factors and evaluating their associations with neonatal morbidity, growth, and neurodevelopment at age 2.
Study design: Prospective …