Medicine and Health Sciences Commons^™

Potential Antimicrobial Methods For Provisionalizing Teeth After Endodontic Treatment, Laura T. Garden

Theses and Dissertations

POTENTIAL ANTIMICROBIAL METHODS FOR PROVISIONALIZING TEETH AFTER ENDODONTIC TREATMENT

By Laura T. Garden, DDS

A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science in Dentistry at Virginia Commonwealth University.

Virginia Commonwealth University, 2018

Thesis Advisor: Garry Myers, DDS

Department of Endodontics

Objective:To evaluate the effectiveness of a Chlorhexidine soaked cotton pellet on bacterial leakage.

Methods: Fifty-one extracted teeth, including six controls, were instrumented, obturated, and sealed with either a cotton pellet (CP), 2% Chlorhexidine soaked cotton pellet (CHX), or a Permaflo orifice barrier (OB). Each root was suspended between two chambers: the …

Orthodontists’ And Patients’ Preferences In Website Design In The Selection Of An Orthodontic Practice: A Comparative Study, Taylor R. Brown

Theses and Dissertations

Objective: To determine which website characteristics are preferred by orthodontists, adult patients, and parents of patients.

Materials and Methods: 1,000 active members of the American Association of Orthodontists and 750 active orthodontic patients/parents were sampled. Participants rated the importance of website characteristics, indicated presence of those characteristics on the current website, and ranked sample website images. Preferences were compared between orthodontist and the patient/parent group using t-tests and sample websites were compared using ANOVA models and Tukey’s adjusted post-hoc tests. Significance level was set at 0.05.

Results: 11 of the 16 website features showed significant differences between patients/parents and orthodontists. …

Change In Working Length At Different Stages Of Instrumentation As A Function Of Canal Curvature, Mei Tang

Theses and Dissertations

The aim of this study was to determine the change in working length (∆WL) before and after coronal flaring and after complete rotary instrumentation as a function of canal curvature. One mesiobuccal or mesiolingual canal from each of 43 extracted molars had coronal standardization and access performed. Once the access was completed, canal preparation was accomplished using Gates Glidden drills for coronal flaring and EndoSequence files for rotary instrumentation. WLs were obtained at 3 time points: pre-instrumentation (unflared), mid-instrumentation (flared) and post-instrumentation (concluded). Measurements were made via direct visualization (DV) and the CanalPro apex locator (EM) in triplicate by a …

The Effects Of Amixicile On Sub-Gingival Biofilm Cultured From Humans, Kian Azarnoush

Theses and Dissertations

Periodontitis is an inflammatory disease of the oral cavity induced by anaerobic bacteria, that remains to be the primary cause of tooth loss in adults worldwide. Finding an anti-microbial therapeutic to selectively target periodontal pathogens has proven to be difficult, and current treatment modalities only provide a transient benefit. Amixicile is a non-toxic, readily bioavailable novel antimicrobial that targets strict anaerobes through inhibition of the activity of Pyruvate Ferredoxin Oxidoreductase (PFOR), a major enzyme mediating oxidative decarboxylation of pyruvate, a critical step in metabolism. Our study aimed to evaluate the efficacy of amixicile in inhibiting the growth of bacteria harvested …

Observations Of Trends And Successes Of Revascularization Therapy At Virginia Commonwealth University: A Retrospective Study, Richard W. Sedwick

Theses and Dissertations

The aim of this study was to determine the trends in protocol, success rates, and consistency in follow up of revascularization procedures in a controlled environment. Patients of the Virginia Commonwealth University School of Dentistry were identified who were offered revascularization therapy as a treatment option on immature permanent teeth from January 1, 2010 to May 31, 2017. A total of 77 patients and 78 teeth were evaluated for revascularization therapy. For patients accepting treatment, records were reviewed for outcome assessment and consistency of follow up. A total of 30 patients (31 teeth) were treated following revascularization protocols, with only …

Efficacy Of Brushing With Probiotics For The Reduction Of Gingivitis, Cheri L. Barton

EWU Masters Thesis Collection

Purpose: The primary aim of this study was to evaluate the efficacy of brushing with the probiotic Lactobacillus reuteri on plaque accumulation and gingival inflammation. This study included 34 healthy adult subjects, ages 18-65, exhibiting gingivitis. Participants were asked to participate in a randomized, double-blind, placebo controlled study testing whether brushing with L. reuteri probiotic drops added to toothpaste reduced the clinical parameters of gingivitis more than brushing with a placebo drop added to toothpaste.

Methods: Biological measurements of plaque accumulation were recorded using disclosing solution and an O’Leary Plaque Score (PS), and gingival inflammation was recorded using a modified …

Identifying Bias In The Transition From Associate To Dental Practice Owner, David G. Dunning

Journal Articles: College of Dentistry

No abstract provided.

Perceptions And Attitudes Of Healthcare Students Towards Marijuana, Carrie Crosby

EWU Masters Thesis Collection

Perceptions of marijuana were studied in healthcare students at EWU. It was found that most students had an average self-reported knowledge of marijuana use. Marijuana comes in several forms such as, edibles, smoked, patches, and lotions. With its recent legalization in Washington State, sales tax alone has accumulated $400 million dollars in the past 3 years. With this increase in use an examination of healthcare students was warranted. Most students also felt there was a need for more education on marijuana and that their current knowledge level was not enough to be competent when talking with patients about use. Overall, …

Oral Care And The Connection To Adverse Events In Dentistry, Melissa A. Rhoney

Walden Dissertations and Doctoral Studies

As the healthcare industry continues to change, dental providers are concerned about the different types of adverse events that can occur if systemic diseases are not well understood when treating patients. The purpose of this study was to explore the level of understanding among dental care providers of the relationship between oral care and systemic diseases and how these are linked to adverse events. The theoretical foundation that was used for this study was the Swiss cheese model. The research questions were designed to address the level of understanding among dental care providers of the link between oral care and …

The Lasting Impact Of Intraprofessional Education Between Dentists And Dental Hygienists, Kimber Satter

EWU Masters Thesis Collection

Purpose: The Regional Initiatives in Dental Education (RIDE) program at the University of Washington (UW) allows first year dental students to take courses with Eastern Washington University dental hygiene (DH) students. This study was conducted to see if the RIDE program is effective as an Intraprofessional Education (IntraPE) program in improving dentists’ attitudes towards teamwork and understanding the roles and responsibilities of the DH.

Methods: UW School of Dentistry alumni from 2012-2017 were invited to participate in this study. Attitudes towards teamwork and roles and responsibilities were assessed using two online surveys: a demographic survey containing open-ended questions, and a …

Exploring Student-Led Interprofessional Education Through A Community Service Project, Lindsay Ann Doerschuk

EWU Masters Thesis Collection

Purpose: The purpose of this research was to explore the effectiveness of a student-led interprofessional education (IPE) workshop in improving student attitudes and perceptions toward IPE. Students from four health science programs including Dental Hygiene, Communication Sciences and Disorders/Speech and Hearing, Health Services Administration and Occupational Therapy participated in a community service event. Students provided screenings to veteran patients including a health history intake, hearing test, and sleep screening while other students observed.

Methods: Students were asked to attend an orientation, the Vets Day IPE workshop, and a debrief session. This mixed methods approach study utilized the Readiness for Interprofessional …

Endoscope Use To Improve Students’ Periodontal Debridement Skills And Self-Efficacy, Sandra J. Walker

EWU Masters Thesis Collection

Purpose: The primary aim of this study was to determine if using the dental endoscope altered dental hygienists’ perception of periodontal disease, changed their instrumentation skills, helped increase self-efficacy, and if multiple uses had an effect on participants’ self-efficacy in debridement skills. Methods: This mixed-method convenient sample study included dental hygienists (N = 34) recruited from Eastern Washington University Bachelor of Science in Dental Hygiene or Master of Science in Dental Hygiene Program. EWU Alumni with at least one experience using the dental endoscope during patient care completed an anonymous self-efficacy survey through SurveyMonkey®. The survey included seven demographic questions, …

Musculoskeletal Disorders Among Brazilian Dentists, Carlos Eduardo Siqueira, Gabriella B Soares, Lorena M Estrada-Martínez, Clea As Garbin

Gastón Institute Publications

OBJECTIVE: This study aimed at investigating the relationships between health and work-related musculoskeletal disorders (WMSDs) in dentists, and the relationship with socio-demographic, work and health variables. METHODS: We conducted a cross-sectional study of 204 dentists who work in public clinics in the state of São Paulo, Brazil. We used a self-administered survey that included questions on socio- demographic and health aspects, work-related factors, and the Nordic questionnaire. RESULTS: WMSDs were often reported in the neck, shoulder, lower back, and hand/wrists. Logistic regression analysis revealed that there was a correlation between reports of WMSD in the neck and age (OR = …

The Effect Of Mechanical Vibration On Pain And Rate Of Tooth Movement During Initial Orthodontic Alignment, Leslie Ellingson

Theses & Dissertations

Purpose: The purpose of this investigation was to evaluate the effect of mechanical vibration on pain experienced and rate of tooth movement (OTM) during the initial alignment phase of orthodontic treatment.

Materials and Methods: Participants were randomly allocated to control, low frequency or high frequency. An electric toothbrush was modified to provide high frequency vibration. A low frequency vibration device was acquired from a commercial vendor. Experimental groups applied vibration to the dentition for 20 minutes daily. All participants completed questionnaires using visual analog scales at five time points. Pain experience was measured in millimeters (mm) with the scale measuring …

Cpap-Mad Combination Therapy For Cpap Intolerant Patients With Moderate To Severe Osa, Jacob Stadiem

Theses & Dissertations

The treatment of obstructive sleep apnea (OSA) allows for a multidisciplinary approach between dentistry and medicine. Continuous positive airway pressure (CPAP) is the gold standard for OSA treatment, but the non-adherence rates are high. The mandibular advancement device (MAD) has a higher acceptance rate than the CPAP, however the efficacy is much lower in cases of moderate to severe OSA. This thesis attempted to evaluate if there was a change in compliance when a MAD was added as a combination therapy to moderate to severe OSA subjects that were currently non-compliant with their CPAP. In addition, the change in air …

What 2017 Holds For Technology In Dentistry, Arshi Siddiqui

Honors College Theses

Dentistry in the United States is a field that grows and expands based on the needs of its consumers. This paper aims to highlight this very versatility through the analysis of specific demographics of dental practitioners, consumers, and the changes in technology that are predicted for the future of dentistry. With the rise of Generation X and the Millennial Generation, dentistry will undergo many changes alongside the rise of technology throughout the recent years. More evidently, the population is undergoing a very seismic shift in the way they view themselves. Because people are harboring more of an individualistic mindset, the …

Ada News - 12/11/2017, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

The Analytical Methods Used To Detect Fluoride In Dental Pharmaceuticals, Amber Aboona

Honors College Theses

My thesis, “The Analytical Methods Used to Detect Fluoride in Dental Pharmaceuticals” discusses the various analytical chemistry methods which are incorporated in the field of dentistry in order to detect fluoride in pharmaceuticals such as toothpaste and mouthwash. The oral cavity is exposed to various forms of bacteria, many of which enter through the consumption of foods and drinks that contain sugar and starch. The side effects of fluoride have been a controversial component of oral healthcare, however, many benefits have been discussed. Water fluoridation has been one of many significant methods of incorporating fluoride into the oral cavity, enhancing …

The Assessment Of A School-Based Dental Program, Peggy H. Hyden

Dental Hygiene ETDs

The Assessment of a School-Based Dental Program

by

Peggy H. Hyden

B.S., Dental Hygiene, Caruth School of Dental Hygiene, Texas A&M College of Dentistry, 1979 M.S., Dental Hygiene, University of New Mexico, 2018

ABSTRACT Purpose: The purpose of this study was to compare non-participants and participants of a school-based dental program and assess the utilization and satisfaction of services offered. Methods: Sixty-seven hundred questionnaires, containing 20 questions, were distributed to the parents/guardians of the Carlsbad and Loving school systems. Surveys were taken home by the students, given to the parent/guardians and returned within 1 week. Descriptive statistics was used to …

Relationship Between Self-Reported Oral Health And Self-Esteem In Two Columbia, Sc Populations, Matthew Ablonczy, Elizabeth Smith

Senior Theses

The importance of oral health to overall health cannot be overstated. For example, oral health can be used for early diagnosis of diseases such as diabetes. Furthermore, it has been well studied that self-esteem is related to oral health. Individuals with proper oral health care have more confidence to interact with others, which results in higher self-esteem. Those who lack the ability to pay for oral healthcare are thus at a great disadvantage. The present study sought to investigate the relationship between oral health and self-esteem in two Columbia, SC populations through surveying. There were two study populations, students at …

Clinical Cases In Endodontics; Chapter 1: Introduction, Takashi Komabayashi

Dental Medicine Faculty Publications

Chapter 1 of Clinical Cases in Endodontics, a problem-based text that presents a wide range of real cases in endodontics. Clinical Cases in Endodontics presents actual clinical cases, accompanied by academic commentary, that question and educate the reader about essential topics in endodontic therapy. It begins with sets of cases illustrating the most common diagnoses and the steps involved in preparing a treatment plan. Subsequent chapters continue in this style, presenting exemplary cases as the basis of discussing various treatment options, including nonsurgical root canal treatment, re-treatment, periapical surgery, internal and external resorption, emergencies and trauma, and treating incompletely developed …

Comparison Of Apical Centring Ability Between Incisal-Shifted Access And Traditional Lingual Access For Maxillary Anterior Teeth, Yoshio Yahata, Yoshiko Masuda, Takashi Komabayashi

Dental Medicine Faculty Publications

The aim of this study was to compare the apical centring ability of incisal-shifted access (ISA) with that of traditional lingual access (TLA). Fifteen three-dimensional printed resin models were prepared from the computed tomography data for a human maxillary central incisor and divided into ISA (n=7), TLA (n=7), and control (n=1) groups. After access preparation, these models were shaped to the working length using K-files up to #40, followed by step-back procedures. An apical portion of the model was removed at 0.5 mm coronal to the working length. Microscopic images of each cutting surface were taken to measure the preparation …

Comparison Of Expression Of The Gdnf Family Neurotrophic Factors In Dental Pulp Stem Cells With Deciduous And Adult Teeth, Kamille Mercado, Nan (Tori) Xiao

All Dugoni School of Dentistry Faculty Articles

The glial cell line-derived neurotrophic factor (GDNF) family has a role in neuron growth within the peripheral and central nervous systems. This makes it a potential therapeutic agent for neurological conditions like Parkinson’s disease and epilepsy. GDNF has also been implicated in murine odontogenesis. In permanent and deciduous human dental pulp stem cells, this study found that GDNF family members and receptors are expressed, indicating neurotrophic factors may play a role in dental pulp regeneration.

Heredity, Genetics And Orthodontics: How Much Has This Research Really Helped?, James K. Hartsfield Jr., George Jeryn Jacob, Lorri Ann Morford

Oral Health Science Faculty Publications

Uncovering the genetic factors that correlate with a clinical deviation of previously unknown etiology helps to diminish the unknown variation influencing the phenotype. Clinical studies, particularly those that consider the effects of an appliance or treatment regimen on growth, need to be a part of these types of genetic investigations in the future. While the day-to-day utilization of "testing" for genetic factors is not ready for practice yet, genetic testing for monogenic traits such as Primary Failure of Eruption (PFE) and Class III malocclusion is showing more promise as knowledge and technology advances. Although the heterogeneous complexity of such things …

The Role Of Kinases And Phosphatases In The Pathobiology Of Porphyromonas Gingivalis., Sarah Whitmore

Electronic Theses and Dissertations

Periodontal diseases result from the interplay between the dysregulation of the host inflammatory response and the actions of a dysbiotic bacterial community. These chronic inflammatory conditions affect persons on a worldwide scale. P. gingivalis is strongly implicated as a key periodontal pathogen in the more severe manifestations of periodontal diseases such as periodontitis. A core element of P. gingivalis pathogenicity is its dysregulation of innate immunity, including suppression of IL-8 production by gingival epithelial cells. The NF-κB family of related transcription factors plays a central role in regulating many important aspects of innate immune responses. NF-κB RelA/p65 homodimers regulate transcription …

Deficiency Of Rdh10 Causes Cleft Secondary Palate In Mouse., Swetha Raja

Electronic Theses and Dissertations

The focus of this project is to understand the role of Retinoic Acid (RA) produced by RDH10-mediated metabolism of Vitamin A in palate development. For 80 years now, we have known that dietary restriction of RA/Vitamin A can cause cleft palate but we have failed to understand how RA deficiency causes cleft palate. Our gap in knowledge about how RA deficiency causes cleft palate is mainly owing to the fact that we lack a model system to study such defects. The aim of this thesis research project was to determine if conditional inactivation of the Vitamin A metabolic gene Rdh10 …

Type Ix Secretion System: Characterization Of An Effector Protein And An Insight Into The Role Of C-Terminal Domain Dimeration In Outer Membrane Translocation., Lahari Koneru

Electronic Theses and Dissertations

Porphyromonas gingivalis and Tannerella forsythia are two of the primary pathogens that are associated in the etiology and progression of chronic periodontitis. In T. forsythia, KLIKK proteases are the recently identified group of proteolytic enzymes that are secreted through Type IX secretion system (T9SS). Among, these KLIKK proteases a synergistic relationship was observed between karilysin and mirolysin in invading the host complement system for the survival of the bacteria. Since, karilysin has been already characterized, in this study we propose to study about mirolysin through structural, biochemical and biological characterization. The obtained results from the experiments has shown the …

Is Antimicrobial Photodynamic Therapy A Useful Therapeutic Protocol For Oral Decontamination? A Systematic Review And Meta-Analysis, Sergio Varelakellesarian, Faisal Qayyum, Paula C.De Freitas, Zohaib Akram, Fawad Javed

Section of Dental-Oral Maxillofacial Surgery

Background: The aim of the present systematic review and meta-analysis was to assess the efficacy of antimicrobial photodynamic therapy (aPDT) as a therapeutic protocol for oral decontamination.
Methods: In order to address the focused question: Is aPDT a useful therapeutic protocol for oral decontamination?, an electronic search without time or language restrictions was conducted up to July 2017 in indexed databases using the combination of different key words including photochemotherapy, lasers, photodynamic therapy, disinfection, mouth, saliva and oral. The exclusion criteria included reviews, case-reports, case-series, commentaries, letters to the editor, interviews, and updates. Four randomized control trials were included and …

Comparison Of Antibacterial Activity Of Ozonated Olive Oil And Chlorhexidine Gluconate, Changmin Lee

Loma Linda University Electronic Theses, Dissertations & Projects

Aim: The aim of this in vitro disk diffusion susceptibility test is to compare the antibacterial activity of ozonated olive oil (OzOO) with chlorhexidine gluconate (CHX) against periodontal pathogens, Porphyromonas gingivalis and Aggregatibacter Actinomycetemcomitans. Materials and Methods: The antibacterial activity of two antiseptics, OzOO and CHX, and, two controls, olive oil and normal saline was assessed by disk diffusion susceptibility test. For disk diffusion susceptibility test, two periodontal pathogens, 20 petri dishes for P. gingivalis and 18 petri dishes for A. actinomycetemcomitans, were used. To assess the antibacterial activity, the diameters of the growth inhibition zone were measured with a …

Healthy Teeth: Building Dental Health Awareness Among Head Start Parents, Marisol Cruz

Capstone Projects and Master's Theses

In the U.S and state of California, tooth decay is the most common chronic disease and concerning health issue among children. The Head Start program in Monterey County serves about 1, 245 children annually from birth to five years of age. One requirement is that children obtain dental health checkups every six months, and receive dental treatment, if needed, as part of adhering to California's dental periodicity schedule. Over the past years, an increase of failed dental health assessments was observed among many children enrolled in the program. Obtaining and following through with treatment was an obstacle. The purpose of …