Medicine and Health Sciences Commons^™

Calibration Of Periodontal Diagnosis Among Participants Of Various Dental Education Levels, Shadi Alkhoury

All ETDs from UAB

ABSTRACT: The purpose of this project is to assess the level of calibration among dental students of two different education levels and postgraduate students of two different dental specialties during diagnosis and treatment planning of clinical cases with various levels of periodontal involvement, using the 2018 Classification of Periodontal and Peri-implant Diseases and Conditions. Fifty-seven second year dental students (D2), 45 fourth year dental students (D4), 17 orthodontic postgraduate students (OS) and 12 postgraduate periodontology (PS) students were presented with an anonymous survey of 10 different cases, each with 5 choices of diagnosis and 7 therapeutic approaches. Consensus diagnosis was …

Functional Significance Of Senescence And Autophagy In Cancer-Associated Fibroblasts From Oral Squamous Cell Carcinoma, May Leng Tan

Student Works (2020-2029)

Oral squamous cell carcinoma (OSCC) is a malignancy that arises from the epithelial cells within the oral cavity. It accounts for approximately 355,000 new cases worldwide and is exceptionally prevalent in particular geographical areas such as Papua New Guinea, the Indian subcontinent and South-East Asian countries. Despite advances in surgical management and therapeutic approaches, the five-year survival rate of OSCC patients has not improved significantly over the past few decades. The mortality associated with OSCC is particularly high often due to late presentation, locoregional recurrence, distant metastases and the development of second primary tumours. A comprehensive understanding of the molecular …

Anticancer Activity Of Ficus Deltoidea And Tualang Honey On Oral Cancer Cells: An In Vivo Study, Alkoshab May Ameen Saeed

Student Works (2020-2029)

The use of natural products have been gaining interest, notably in the area of cancer therapy and in this study, natural products rich in antioxidants such as Tualang Honey (Malaysian wild local honey) and Ficus deltoidea (Malaysian local herbal plant), were selected to assess their chemo-preventive and chemotherapeutic activities on oral cancer. The aim of this study is to evaluate the chemo-preventive and chemotherapeutic activities of Ficus deltoidea (FD) and Tualang Honey (TH) in an animal model induced for oral cancer using 4-Nitroquinoline1-oxide (4NQO). A total of 70 male Sprague-Dawley (SD) rats were distributed into ten groups (n=7 per group); …

A Three Dimensional Age Estimation Using Cone Beam Ct In Malaysian Population, Asif Muhammad Khan

Student Works (2020-2029)

Forensic odontology plays a vital role in the age estimation and identification process during criminal investigations. Forensic science in the past have mainly employed two-dimensional (2D) radiographic assessment of developmental and physiological age related dental parameters for age estimation. However, 2D radiograph doesn’t represent the three-dimensional (3D) anatomical structures. Rapidly evolving CBCT imaging modality can be effectively employed in forensic sciences to overcome the limitations of 2D imaging. The current study aimed to develop a novel method of dental age estimation using 3D surface area analyses of root apices of the developing permanent maxillary canines and mandibular third molars among …

Identification Of Potential Biomarkers Of Oral Squamous Cell Carcinoma Using Integrated Proteomics And Glycoproteomics And Glycoproteomics Analyses, Yin Ling Wong

Student Works (2020-2029)

Oral cancer is one of the major health concerns worldwide. The 5-year survival rate of oral squamous cell carcinoma (OSCC) has remained at approximately 50% over the past decades. Most OSCCs are diagnosed at an advanced stage due to the delay in diagnosis, suggesting an imperative need in identifying reliable biomarkers to improve the diagnosis, prognosis, and treatment of OSCC. This study aimed to identify potential biomarkers that are involved in the development and progression of OSCC using integrated proteomics and glycoproteomics analyses. Proteomics analysis was performed on serum samples of 10 patients with oral potentially malignant disorder (OPMD), 40 …

Patient Concerns Inventory Head And Neck As An Individualised Approach To Assess Post-Treatment Outcomes Among Oral Cancer Patients In Malaysia, Aminnudin Ainon Natrah

Student Works (2020-2029)

Background: Oral cancer and its treatment undisputedly impacts patients‘ quality of life, posing a challenge to clinicians in managing them optimally. Identifying patients‘ concerns is central to holistic patient care; as such time constraints faced by clinicians during consultation sessions may pose a barrier in identifying such concerns effectively. The use of PCI-H&N during post-treatment oral cancer consultation sessions has previously shown to be beneficial, simultaneously promoting effective patient- clinician communication during consultations. Objectives: This study aimed to determine the feasibility of the PCI-H&N in assessing post- treatment oral cancer patients concerns and its relationship with patients‘ HRQoL, psychological distress …

Tubular Adenoma Of Breast, Diksha Dadlani

Digital Journal of Clinical Medicine

No abstract provided.

Kikuchi-Fujimoto Disease, Rohan Karkra

Digital Journal of Clinical Medicine

No abstract provided.

Macular And Optic Disc Drusenoid Deposits With Hemifield Defects In A Patient With Iga Nephropathy: New Findings, Dr. Prabhakar S K

Digital Journal of Clinical Medicine

No abstract provided.

A Case Of Megaloblastic Anemia With Suspected Gilbert Syndrome, Nair A, Prasad R, Dr. Ravikumar S, Dr. Prasanna Kumar

Digital Journal of Clinical Medicine

No abstract provided.

A Case Of Recurrent Pregnancy Loss Due To Bicornuate Uterus, Chandran S

Digital Journal of Clinical Medicine

No abstract provided.

A Case Of Right Lower Lobe Lung Abscess With Stage Iii Empyema, Dey Sauparna, Dr. Ravi M D

Digital Journal of Clinical Medicine

No abstract provided.

Uterine Prolapse, Nimisha Sinha, Sakshi Anurika, Dr. Anu Prerana

Digital Journal of Clinical Medicine

No abstract provided.

Ataxia Telangiectasia- A Case Report, Pooja Pallavi, Dr. Rajani H.S

Digital Journal of Clinical Medicine

No abstract provided.

A Case Of Sjogren’S Syndrome With Leucocytoclastic Vasculitis With Hypokalemic Periodic Paralysis, Dr. Pranay Penmetsa, Dr. Subramanian R

Digital Journal of Clinical Medicine

No abstract provided.

“Hunting” A Case Of External Ophthalmoplegia: Tolosa-Hunt Syndrome, Dr Vaishnavi S.G, Dr Shasthara P

Digital Journal of Clinical Medicine

No abstract provided.

A Case Of Tenofovir Induced Osteopenia, Dr Kruthi M, Dr Rajendra Prasad S

Digital Journal of Clinical Medicine

No abstract provided.

Aadej Comm 6 1 2020

AADEJ - The Communicator

The Communicator is the official journal of the American Association of Dental Editors and Journalists (AADEJ). It is published quarterly, distributed digitally via email to members, and posted on the Association's website, AADEJ.org. Each issue includes regular updates from the editorial team and AADEJ board, as well as feature articles on current issues in the field.

Aadej Comm 6 3 2020

AADEJ - The Communicator

The Communicator is the official journal of the American Association of Dental Editors and Journalists (AADEJ). It is published quarterly, distributed digitally via email to members, and posted on the Association's website, AADEJ.org. Each issue includes regular updates from the editorial team and AADEJ board, as well as feature articles on current issues in the field.

Functionalized Scaffold And Barrier Membrane With Anti-Bmp-2 Monoclonal Antibodies For Alveolar Ridge Preservation In A Canine Model, Seiko Min, Taewan Kim, Oksu Kim, Carames Goncalo, Tadahiko Utsunomiya, Takashi Matsumoto, Kayo Kuyama, Nikola Angelov

Faculty, Staff and Student Publications

INTRODUCTION: The aim of this study was to investigate the ability of anti-bone morphogenetic protein 2 monoclonal antibody (anti-BMP-2 mAb) to functionalize scaffolds to mediate bone regeneration in a canine model.

MATERIALS AND METHODS: The mandibular right premolar 4 (PM4) was extracted in eight beagle dogs and grafted with anti-BMP-2 mAb+anorganic bovine bone mineral with 10% collagen (ABBM-C) and porcine bilayer native collagen membrane (CM). The ABBM-C and CM were functionalized with either anti-BMP-2 mAb (test group) or an isotype matched control mAb (control group). Animals were euthanized at 12 weeks for radiographic, histologic, and histomorphometric analyses. Outcomes were compared …

Distinct Profiles Of Specialized Pro-Resolving Lipid Mediators And Corresponding Receptor Gene Expression In Periodontal Inflammation, Brittney Ferguson, Nishantha R Bokka, Krishna Rao Maddipati, Srinivas Ayilavarapu, Robin Weltman, Lisha Zhu, Wanqi Chen, W Jim Zheng, Nikola Angelov, Thomas E Van Dyke, Chun-Teh Lee

Faculty, Staff and Student Publications

Polyunsaturated fatty acid-derived specialized pro-resolving lipid mediators (SPMs) play an important role in modulating inflammation. The aim of the study was to compare profiles of SPMs, SPM related lipid mediators and SPM receptor gene expression in gingiva of subjects with periodontitis to healthy controls. A total of 28 subjects were included; 13 periodontally healthy and 15 periodontitis before or after non-surgical periodontal therapy. Gingival tissues were collected from two representative posterior teeth prior to and 8 weeks after scaling and root planning; only once in the healthy group. Lipid mediator-SPM metabololipidomics was performed to identify metabolites in gingiva. qRT-PCR was …

Systemic Th17 Response In The Presence Of Periodontal Inflammation, Lina J Suárez, Daniel E Vargas, Adriana Rodríguez, Roger M Arce, Nelly S Roa

Faculty, Staff and Student Publications

BACKGROUND: The relationship between periodontitis and the pathogenesis of other inflammatory diseases, such as diabetes, rheumatoid arthritis and obesity has been an important topic of study in recent decades. The Th17 pathway plays a significant role in how local inflammation can influence systemic inflammation in the absence of systemic pathology.

OBJECTIVE: To determine Th17 biased-cells in systemically healthy patients in the presence of generalized chronic periodontitis.

METHODOLOGY: A total of 28 patients were recruited without systemic inflammatory pathology, which was determined by clinical history, the Health Assessment Questionnaire (HAQ) and rheumatoid factor detection. Of these patients, 13 were diagnosed as …

Perception Of Stress Observed By Family Members Of Dentists Who Have Committed Suicide, Lillian D. Williams

Walden Dissertations and Doctoral Studies

Research aimed at the observed stress from being a dentist, and how it may have

impacted the occurrence of their suicide did not appear to be prevalent among empirical

suicide studies. The purpose of this basic, qualitative study was to explore how the

family members perceived occupational stress as precursor events in dentists who

committed suicide. Using the interpersonal theory of suicide as the conceptual basis, 4

family members of dentists who committed suicide were interviewed to understand how

family members perceived occupational stress in the dentist using semi structured

interviews. Through a series of precoding and recoding, interview data …

A Cephalometric Study Of The Effects Of Class Ii Malocclusion Correction Utilizing The Carriere® Motion 3d Appliance And Essix Retainer, Julie Dean

All ETDs from UAB

Objective: The purpose of this study is to determine the dental and skeletal effects of Class II malocclusion correction with a Carriere® Motion 3D appliance and lower Essix retainer for anchorage, as compared to best-matched controls. Methods: This is a retrospective case-control cephalometric study uses pre- and post-distalization lateral cephalometric images from 44 (32 female, 12 male, average age 13y 7m) class II patients treated with a Carriere® Motion 3D appliance and lower Essix retainer. These films were analyzed to determine treatment effects and compared with 35 (17 female, 18 male, average age 13y 3m) untreated controls from a historical …

Development Of Natural Language Processing Algorithm For Dental Charting, Yi-Fan Zhang

All ETDs from UAB

Purpose: The purpose was to develop a natural language processing algorithm, which will input data from oral examination transcripts to a structured database. Methods: Four case vignettes were produced for primary, mixed, and permanent dentition patients with varying degree of soft tissue pathology, caries, existing restorations and occlusion relationships. After calibration, dental students were instructed to perform simulated oral examinations based on the case vignettes, using natural language as they would to an assistant who was charting the case. The investigator transcribed the audio recordings of the simulated oral exams. Twenty simulated oral examinations were collected to develop a natural …

The Retention Of Zirconia Crowns Luted With Resin And Rmgi Cements And The Effect Of Salivary Contamination, Stephen Liu

All ETDs from UAB

Purpose: To measure retention of zirconia crowns bonded with resin and RMGI cements and the effect of salivary contamination following 10,000 cycles of thermocycling. Materials and Methods: 64 extracted human mandibular premolars were divided into eight groups (n = 8/group). The specimens in each group were prepared for Katana HT zirconia (eight groups) and one of four luting cements (one for each group): 3M ESPE RelyX Luting Plus RMGI, 3M ESPE Rely X Unicem 2 self-adhesive, Kuraray Panavia SA Universal self-adhesive, and 3M ESPE RelyX Ultimate dual cure resin cement with Scotchbond Universal. The roots of the selected teeth were …

Nonsyndromic Hypodontia Of Maxillary Lateral Incisors, Its Genetics And Its Association With Other Dental Anomalies, Giana Lupinetti

All ETDs from UAB

NONSYNDROMIC HYPODONTIA OF MAXILLARY LATERAL INCISORS, ITS GENETICS, AND ITS ASSOCIATION WITH OTHER DENTAL ANOMALIES GIANA LUPINETTIDEPARTMENT OF ORTHODONTICS ABSTRACT Congenital absence of maxillary lateral incisors presents a difficult situation for clini-cians for restorative and orthodontic purposes. Further, missing lateral incisor agenesis (MLIA) has been associated with other dental anomalies and cancer. 1 Few studies have targeted MLIA as a specific subtype of hypodontia. WNT10A is a candidate gene for MLIA. 2 The hypothesis was that genetic mutations in WNT10A affect maxillary lateral tooth development and can contribute to other dental anomalies. The first aim was to evaluate patients with …

Effect Of Cement Selection On Retention Of Zirconia And Lithium Disilicate Crowns, Chan-Te Huang

All ETDs from UAB

Background: Ceramic crowns (lithium disilicate and zirconia) have become the most prescribed material for the restoration of anterior and posterior teeth due to the esthetic concerns of patients and the high cost of noble alloys. Different types of cements are used for luting crowns such as zinc phosphate, glass ionomer, resin modified glass ionomer (RMGI), resin cements and bioactive cements. Selection of different cements and bonding protocols for zirconia or lithium disilicate crowns to increase their bonding strength remains a clinical challenge for dentists. Objectives: To measure the retention strength of lithium disilicate and zirconia crowns cemented with different cements. …

In Vitro Evaluation Of Candida Albicans Adherence And Disinfection Techniques On Cad/Cam Milled, 3d Printed, And Heat-Cured Pmma, Mohammad Amir Koujan

All ETDs from UAB

INTRODUCTION: Candida albicans has been regarded as the most predominant oral fungal pathogen and the main causative of denture stomatitis. Modern denture are fabricated from various types of polymers commonly: CAD/CAM or heat-cured. C. albicans adherence rate to these polymers and disinfection efficacy of adherent fungal biofilms are multifactorial processes and differ depending on the physical characteristics of the targeted surface. PURPOSE: The purpose of this study was to investigate Candida albicans adherence to specimens from three types of polymers namely: heat-cured PMMA, CAD/CAM milled and 3D printed. The second part compares the efficacy of four common disinfection techniques on …

The Influence Of Maxillary Sinus Anatomy On Schneiderian Membrane Perforation During Lateral Wall Sinus Augmentation: A 5-Year Retrospective Study, Andrea Pizzini

All ETDs from UAB

Although previous studies have attempted to identify risk factors for membrane perforation, limited information with conflicting data exists regarding the significance of the relationship between buccal wall thickness and membrane perforation. Access to the Schneiderian membrane during the sinus augmentation procedure is obtained through the buccal wall, thus the importance of understanding whether its thickness plays a role in membrane perforations. In addition, the anatomy of the sinus cavity plays an important role in rendering the sinus augmentation procedure straightforward or rather complex. It is theorized that the narrower the sinus cavity, the higher the risk of membrane perforation. Residual …