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Articles 2401 - 2430 of 13211
Full-Text Articles in Medicine and Health Sciences
Intersectionality, Racial Discrimination And Oral Healthcare Utilization Among Black Adults In Baltimore City, Maryland, Briona M. Phillips
Intersectionality, Racial Discrimination And Oral Healthcare Utilization Among Black Adults In Baltimore City, Maryland, Briona M. Phillips
Theses and Dissertations
INTRODUCTION: Oral health is essential for overall well-being, yet disparities persist, particularly among marginalized populations including Black adults. Limited access to and underutilization of oral healthcare services exacerbate these disparities. Discrimination, both individual and systemic, acts as a significant barrier to accessing care, contributing to disparities in oral health outcomes. Individuals facing discrimination experience mistrust and fear within oral healthcare settings, leading to delayed or avoided care. Therefore, investigating and addressing discrimination among Black adults is essential for promoting equitable access to oral healthcare, improving overall oral health outcomes, and lessening existing disparities.
PURPOSE: The purpose of this dissertation was …
Diagnostic Accuracy Of Cbct In The Differential Diagnosis Of Apical Cysts And Granulomas Using Histopathological Findings As A Reference Standard: A Systematic Revew, Fatima Zohra Rouggani, Chaimaa Kabil, Rachida Mayou, Sidi Mohamed . Bouzoubaa
Diagnostic Accuracy Of Cbct In The Differential Diagnosis Of Apical Cysts And Granulomas Using Histopathological Findings As A Reference Standard: A Systematic Revew, Fatima Zohra Rouggani, Chaimaa Kabil, Rachida Mayou, Sidi Mohamed . Bouzoubaa
Health Sciences
Introduction
The periapical lesions represent a complex group. Granulomas and cysts represent the two most frequent forms in routine clinical practice.
Aim: Highlight the diagnostic accuracy of CBCT imaging in the differential diagnosis between a cyst and a granuloma compared to histopathological examination as a reference technique.
Materials and Methods:
Our literature search involved articles published in the following databases: PubMed, Cochrane, science direct and Google scholar.
Our intention was to review recent articles from the last 5 years and to select studies conducted in significantly changed socio-medical contexts that could have a positive impact on the validity of our …
Inclusive Integration Of Refugees And Migrants In Djibouti's National Healthcare System: Current Situation And Prospects For Improvement, Farhan Houssein Ali, Njah Mansour, Kenza Hassouni
Inclusive Integration Of Refugees And Migrants In Djibouti's National Healthcare System: Current Situation And Prospects For Improvement, Farhan Houssein Ali, Njah Mansour, Kenza Hassouni
Health Sciences
Cet examen narratif vise à décrire et synthétiser les données actuelles sur la situation des migrants et des réfugiés à Djibouti, ainsi que les progrès de la stratégie d'intégration inclusive mise en œuvre par le gouvernement djiboutien. Il s'appuie sur diverses sources, notamment la littérature grise et les publications scientifiques. Les résultats indiquent que le nombre de migrants et de réfugiés est en augmentation constante depuis 2019, avec un état de santé vulnérable et des risques sanitaires alarmants. Il est urgent d'accélérer la mise en œuvre de la stratégie tout en l'adaptant aux données actuelles et d'établir un système fiable …
Dental Outreach In Academic Dental Settings, Tisha Clayborn
Dental Outreach In Academic Dental Settings, Tisha Clayborn
Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)
Creating an effective outreach program in a dental academic setting involves a strategic approach combining educational objectives and community service. This Dental Outreach Program Guide aligns with organizational objectives, contributes to community well-being, and serves as a model for future outreach initiatives in academic dental settings. This program utilizes the PRECEDE-PROCEED planning model to design and evaluate an oral health strategy. This program aims to outline a strategic plan incorporating evidence-based decision-making, data-driven metrics, and a comprehensive roadmap for successful implementation.
Effect Of Adjunctive Incorporation Of Nanoparticles Of Amorphous Calcium Phosphate And Chlorhexidine On Properties Of An Etch-And-Rinse Bonding Agent, Hussein Elshikha, Elsayed Gad, Noha Sheta
Effect Of Adjunctive Incorporation Of Nanoparticles Of Amorphous Calcium Phosphate And Chlorhexidine On Properties Of An Etch-And-Rinse Bonding Agent, Hussein Elshikha, Elsayed Gad, Noha Sheta
Mansoura Journal of Dentistry
Objective: To assess the effect of the addition of nanoparticles of amorphous calcium phosphate (NACP) and chlorhexidine (CHX) on the properties of an etch-and-rinse adhesive regarding the bond strength to caries-affected dentine (CAD) and the NACP remineralization efficacy.
Materials and Methods: Dentine surfaces from 80 human molars were subjected to pH cycling and then divided into 4 groups (n=20): adhesive without additives (control group), 5% wt/wt NACP added to the adhesive (NACP group), 0.1% CHX added to the adhesive (CHX group), and addition of 5%wt/wt NACP and 0.1% CHX to the adhesive (NACP+CHX group). After acid etching, the adhesive for …
Ada Constitution & Bylaws (2024), American Dental Association
Ada Constitution & Bylaws (2024), American Dental Association
Constitution & Bylaws
The ADA Commons Constitution & Bylaws archival collection comprises printed issues of the American Dental Association's Constitution and Bylaws. The collection also includes the ADA Charter and the ADA Code of Ethics issued 1924-1946.
The Impact Of Occlusal Splint Therapy And Vitamin D On The Management Of Temporomandibular Disorders, Mostafa S. Swedan, Magdy Mohamed Zaky Hussein, Sherin Fathy Donia, Mohamed Tarek Hussein Khater
The Impact Of Occlusal Splint Therapy And Vitamin D On The Management Of Temporomandibular Disorders, Mostafa S. Swedan, Magdy Mohamed Zaky Hussein, Sherin Fathy Donia, Mohamed Tarek Hussein Khater
Mansoura Journal of Dentistry
Objective: The purpose of this study is to evaluate the Vitamin D supplementation as an adjuvant therapy for stabilization splint in patients exhibiting temporomandibular disorders (TMD).
Materials and Methods: This study involved 100 TMD divided into two equal groups each of 50 patients; group 1: treated by occlusal splint plus vit D and group 2: treated by vitamin D only. All patients in adult age, more than 18 years. All patients were accepted without regard to their financial situation, caste, gender, or religion. Less than 30 ng/mL of vitamin D was present, the teeth were either completely dentate or had …
Infographic: Equity Opportunities: Race And Ethnicity: Need For Dental Care Among Third Grade Students In North Dakota, Shawnda Schroeder
Infographic: Equity Opportunities: Race And Ethnicity: Need For Dental Care Among Third Grade Students In North Dakota, Shawnda Schroeder
Indigenous Health Faculty Publications
Third grade students who are American Indian or Black/African American have a significantly higher need for early or urgent dental care than those who are non-Hispanic white. Those who are American Indian or Hispanic/Latinx have a significantly higher rate of rampant decay than those who are non-Hispanic white.
Creating Smiles With Digital Workflow And Matrix Transfer Technique In Customizing Personality-Based Smile Designing, Jahnavi Purna Gorripati, Surekha Godbole
Creating Smiles With Digital Workflow And Matrix Transfer Technique In Customizing Personality-Based Smile Designing, Jahnavi Purna Gorripati, Surekha Godbole
International Arab Journal of Dentistry
Introduction: This report is a presentation of a clinical case that follows the Visagism concept for 2D planning and, CAD (Exo CAD) for 3D desiging along 3D printed diagnostic wax-up model for closure of anterior spacing.
Case presentation: A 24-year-old man presented with midline diastema and anterior spacing 11-13, 21-23 and wants a smile designed. This concern was solved following a smile design (VisagiSMile) planning digitally for diagnostic wax and printing a 3D model. The matrix transfer technique has been used to directly convey planned information from 3D-printed diagnostic wax-up to definitive restorations.
Conclusions: In this day …
Histological Evaluation Of Pulp Response To Pulpine Ne Versus Biodentine As Direct Pulp Capping Materials In A Dog Model, Hagar Bastawy, Maha Ahmed Niazy, Mona Farid, Asmaa Harhash, Mona Aboelwafa, Ashraf Abu-Seida
Histological Evaluation Of Pulp Response To Pulpine Ne Versus Biodentine As Direct Pulp Capping Materials In A Dog Model, Hagar Bastawy, Maha Ahmed Niazy, Mona Farid, Asmaa Harhash, Mona Aboelwafa, Ashraf Abu-Seida
International Arab Journal of Dentistry
Introduction: The material used for pulp capping has a significant impact on the outcome of vital pulp therapy. This study compared the pulp tissue response to Pulpine NE versus Biodentine as direct pulp capping materials in a dog model.
Methods: Twenty-four teeth in two mongrel dogs (1-2-year-old) were used. In each dog (n=12 teeth), the dental pulps were exposed in 8 teeth (2 experimental groups, 4 teeth each) and left unexposed in 4 teeth (control group, n=4 teeth). A class V cavity was performed on the buccal surface of the selected teeth in the experimental groups. The exposed …
Nasoalveolar Molding: A Rise In Early Management Of Newborn Patient With Cleft Lip And Palate, Reeya Agrawal, Pallavi Daigavane, Amit Reche
Nasoalveolar Molding: A Rise In Early Management Of Newborn Patient With Cleft Lip And Palate, Reeya Agrawal, Pallavi Daigavane, Amit Reche
International Arab Journal of Dentistry
Orofacial clefts are one of the most frequent congenital oral and maxillofacial abnormalities. When these babies are roughly three months old, lip rebuilding, also known as cheiloplasty, is a critical concern. In several cleft facilities, To improve the treatment success, presurgical Nasoalveolar Molding (NAM) has been included in the therapy protocol. In patients with cleft lip and palate, this technique is routinely used to bring the alveolar segments into normal alignment and improve nasal symmetry. In this article, the benefits of using this method as part of a treatment plan for infants with cleft lip and palate will be described. …
Synopsis On The Role Of Diode Laser In Root Canal Disinfection, Ashraf Abu-Seida, Mohamed El-Tayeb, Elhassan Hassanein
Synopsis On The Role Of Diode Laser In Root Canal Disinfection, Ashraf Abu-Seida, Mohamed El-Tayeb, Elhassan Hassanein
International Arab Journal of Dentistry
Effective root canal disinfection is necessary for success of endodontic treatment. Traditional chemo-mechanical techniques such as sodium hypochlorite, mechanical preparation and calcium hydroxide used for intracanal disinfection usually fail in cases of biofilm-related infections. Therefore, several new strategies are applied for root canal disinfection. One of these strategies is using of diode laser that has recently gained significant attention in the endodontic practice due to its antibacterial action, bio-stimulation, decrease of pain and improvement of success. Moreover, it has several advantages like its low cost, easily application, penetration power into dentine and smaller size device compared with other types of …
Exploring And Describing Current Behavioral And Social Sciences Curricula In Predoctoral Dental Programs, Casey D. Wright, Lance Brendan Young
Exploring And Describing Current Behavioral And Social Sciences Curricula In Predoctoral Dental Programs, Casey D. Wright, Lance Brendan Young
School of Dentistry Faculty Research and Publications
Purpose
To maintain accreditation status, predoctoral dental programs in the United States and Canada are required to train future dentists in the fundamentals of behavioral sciences. Each program independently determines how to fulfill this task, and little information exists on the consistency of training across programs. The purpose of this study was to identify the range of topics currently taught in predoctoral dental programs in the United States and Canada, who teaches them, and the modes of instruction and assessment.
Methods
Invitations to complete an online survey were emailed to faculty responsible for, or familiar with, the behavioral sciences curricula …
Immunohistochemical Analysis Of Dentigerous Cysts And Odontogenic Keratocysts Associated With Impacted Third Molars—A Systematic Review, Luis Eduardo Almeida, David Lloyd, Daniel Boettcher, Olivia Kraft, Samuel Zammuto
Immunohistochemical Analysis Of Dentigerous Cysts And Odontogenic Keratocysts Associated With Impacted Third Molars—A Systematic Review, Luis Eduardo Almeida, David Lloyd, Daniel Boettcher, Olivia Kraft, Samuel Zammuto
School of Dentistry Faculty Research and Publications
Objective: This systematic review investigates the diagnostic, prognostic, and therapeutic implications of immunohistochemical markers in dentigerous cysts (DCs) and odontogenic keratocysts (OKCs) associated with impacted third molars.
Materials and Methods: A comprehensive search strategy was employed across major databases including MEDLINE/PubMed, EMBASE, and Web of Science, from the inception of the databases to March 2024. Keywords and Medical Subject Heading (MeSH) terms such as “dentigerous cysts”, “odontogenic keratocysts”, “immunohistochemistry”, “Ki-67”, and “p53” were used. The PRISMA 2020 guidelines were followed to ensure methodological rigor. Inclusion criteria encompassed studies on humans and animals providing definitive diagnoses or specific signs and symptoms …
Evaluating Surgical Approaches For Hemimandibular Hyperplasia Associated With Osteochondroma: A Systematic Literature Review, Luis Eduardo Almeida, Samuel Zammuto, Diego Fernando Lopez
Evaluating Surgical Approaches For Hemimandibular Hyperplasia Associated With Osteochondroma: A Systematic Literature Review, Luis Eduardo Almeida, Samuel Zammuto, Diego Fernando Lopez
School of Dentistry Faculty Research and Publications
Background/Objectives: Hemimandibular hyperplasia (HH) associated with osteochondroma presents complex challenges in maxillofacial surgery, including facial asymmetry, occlusal instability, and temporomandibular joint (TMJ) dysfunction. Surgical interventions vary widely in approach and outcomes, underscoring the need for a systematic evaluation of effectiveness. This systematic review assesses the effectiveness of surgical approaches for managing HH associated with osteochondroma, focusing on techniques including condylectomy, orthognathic surgery, distraction osteogenesis, total joint replacement (TJR), and genioplasty. Methods: Following PRISMA 2020 guidelines, a comprehensive search was conducted in PubMed, Scopus, and Web of Science for studies published from 2000 to 2023. Eligibility criteria were based on the …
Bayesian Rare Variant Analysis Identifies Novel Schizophrenia Putative Risk Genes, Shengtong Han
Bayesian Rare Variant Analysis Identifies Novel Schizophrenia Putative Risk Genes, Shengtong Han
School of Dentistry Faculty Research and Publications
The genetics of schizophrenia is so complex that it involves both common variants and rare variants. Rare variant association studies of schizophrenia are challenging because statistical methods for rare variant analysis are under-powered due to the rarity of rare variants. The recent Schizophrenia Exome meta-analysis (SCHEMA) consortium, the largest consortium in this field to date, has successfully identified 10 schizophrenia risk genes from ultra-rare variants by burden test, while more risk genes remain to be discovered by more powerful rare variant association test methods. In this study, we use a recently developed Bayesian rare variant association method that is powerful …
Association Between Periodontal Health Status And Quality Of Life: A Cross-Sectional Study, Kinan M. Al-Bitar, Jeffery M. Garcia, Shengtong Han, Arndt Guentsch
Association Between Periodontal Health Status And Quality Of Life: A Cross-Sectional Study, Kinan M. Al-Bitar, Jeffery M. Garcia, Shengtong Han, Arndt Guentsch
School of Dentistry Faculty Research and Publications
Introduction: Attachment loss due to periodontal diseases is associated with functional limitations as well as physical pain and psychological discomfort, which may lead to a reduced quality of life. The purpose of this study is to determine if the oral health status, specifically the periodontal status, influences oral health–related quality of life.
Materials and methods: Survey data were collected in a US dental school clinical setting in a cross-sectional study. Quality of life related to oral health was assessed with the Oral Health Impact Profile-49 (OHIP-49). In addition, DMFT index, periodontal status, and health literacy scores (dental and medical health …
The Effect Of Speed Sintering On The Optical Properties And Microstructure Of Multi-Layered Cubic Zirconia, Ahmed Sabet
The Effect Of Speed Sintering On The Optical Properties And Microstructure Of Multi-Layered Cubic Zirconia, Ahmed Sabet
Dentistry
Purpose: Speed sintering was introduced to fabricate time-efficient chairside restorations, however, its influence on the microstructure and optical properties of zirconia is still unclear. This study investigated the influence of speed sintering on the microstructure and optical properties of ultra-translucent multi-layered cubic zirconia. Materials and methods: Ultra-translucent cubic zirconia (Katana™ UTML; Kuraray Noritake Dental Inc., Aichi, Japan) was cut into a total of 80 specimens, twenty within each layer of the blank. The specimens were divided into 2 groups: speed and conventional sintering. The translucency parameter, opalescence, chromaticity, and color difference were recorded using a spectrophotometer. Scanning electron microscope images …
Dysplasia In Oral Lichen Planus In A Sample Of Egyptians Attending 2 Tertiary Care Centers In Cairo, Dalia Ghalwash, Ayman El-Gawish
Dysplasia In Oral Lichen Planus In A Sample Of Egyptians Attending 2 Tertiary Care Centers In Cairo, Dalia Ghalwash, Ayman El-Gawish
Dentistry
The present retrospective study aimed to evaluate dysplastic changes in oral lichen planus (OLP) lesions and related risk factors in a sample of Egyptians. The records of patients with histological diagnosis of OLP, who attended the Oral Medicine and Periodontology Department, Faculty of Dentistry, Cairo University, and Faculty of Dentistry, the British University in Egypt, in the period from 2020 to 2023 were used. The frequency of dysplasia was 10.19% and was statistically not associated with age, gender or smoking. Our results showed that the erosive type registered the highest rate (p<0.001), followed by atrophic, whereas papular type did not show dysplasia. Also, the most common site for dysplasia was the buccal mucosa and tongue (p<0.001 and p=0.001, respectively), then gingiva, lips, and floor of the mouth. Given the importance of OLP, among the Egyptian population seeking care in our clinics, more research should be conducted to create a database of statistical information.
https://doi.org/10.1111/odi.151
Comparison Between Injectable Platelet Rich Fibrin With Collagen Carrier And Β-Tricalcium Phosphate In Lateral Maxillary Sinus Lift With Simultaneous Implant Placement, Ahmed Adel Refaat, Noha Ahmed Mansour, Sally Awad
Comparison Between Injectable Platelet Rich Fibrin With Collagen Carrier And Β-Tricalcium Phosphate In Lateral Maxillary Sinus Lift With Simultaneous Implant Placement, Ahmed Adel Refaat, Noha Ahmed Mansour, Sally Awad
Mansoura Journal of Dentistry
Objective: This study aimed to compare injectable PRF (I-PRF) with a collagen carrier and β-Tricalcium Phosphate (β-TCP) for maxillary sinus floor augmentation (MSFA) with simultaneous implant placement.
Materials and methods: Fourteen patients with missed maxillary posterior teeth and 3-5 mm residual bone height (RBH) were selected to perform lateral MSFA with simultaneous implant placement. A total of 18 sites (implants) in 13 patients were qualified for analysis, 10 sites with I-PRF and collagen carrier (group I) and 8 sites with β-TCP (group II). Six months later, implant stability was recorded, and all sites were analyzed using cone-beam computed tomography (CBCT) …
การประเมินการต้านทานการแตกหักในฟันหน้าที่ผ่านการเหนี่ยวนำให้ปลายรากฟันปิดด้วยเอ็มทีเอและได้รับการเสริมความแข็งแรงของคลองรากฟัน: การศึกษาในห้องทดลอง, ธัญพฤฒ อุตมวาทิน
การประเมินการต้านทานการแตกหักในฟันหน้าที่ผ่านการเหนี่ยวนำให้ปลายรากฟันปิดด้วยเอ็มทีเอและได้รับการเสริมความแข็งแรงของคลองรากฟัน: การศึกษาในห้องทดลอง, ธัญพฤฒ อุตมวาทิน
Chulalongkorn University Theses and Dissertations (Chula ETD)
การแตกของรากฟันเป็นความล้มเหลวที่พบได้บ่อยในฟันที่ได้รับการเหนี่ยวนำให้ปลายรากฟันปิดด้วยเอ็มทีเอ งานวิจัยนี้จึงมีวัตถุประสงค์เพื่อศึกษาวัสดุเสริมความแข็งแรงที่เหมาะสมภายหลังการเหนี่ยวนำให้ปลายรากฟันปิดด้วยเอ็มทีเอภายใต้สภาวะจำลองในช่องปาก โดยแบ่งการศึกษาออกเป็น 2 ตอน ตอนที่ 1: เพื่อศึกษาผลของความหนาของเนื้อฟัน ฟันจำนวน 24 ซี่ (n=8) ถูกแบ่งเป็น 3 กลุ่ม ได้แก่ กลุ่มควบคุมที่มีรากฟันสมบูรณ์ กลุ่มที่จำลองให้มีความหนาเนื้อฟัน 2.0 มม. และ 1.5 มม. โดยใช้ Peeso reamer ขยายโพรงรากจนได้ความหนาตามที่กำหนด ตอนที่ 2: เพื่อศึกษาผลของวัสดุเสริมความแข็งแรง รากฟันจำนวน 40 ซี่ถูกเตรียมให้มีลักษณะรากอ่อนแอโดยจำลองความหนาเนื้อฟัน 1.5 มม. และปิดปลายรากด้วยเอ็มทีเอจากนั้นแบ่งเป็น 5 กลุ่ม (n=8) ได้แก่ กลุ่มกัตทาเพอร์ชา, เอ็มทีเอ, เรซินคอมโพสิตชนิดบ่มตัวร่วม, เดือยฟันเสริมเส้นใย และเดือยฟันเสมือนรากฟัน ทุกกลุ่มตัวอย่างผ่านกระบวนการเปลี่ยนอุณหภูมิร้อนเย็นแบบเป็นจังหวะและการลงแรงแบบเป็นวัฏจักร ก่อนทดสอบการรับแรงกดจนแตก บันทึกลักษณะการแตกและแรงสูงสุดก่อนการแตก วิเคราะห์ข้อมูลด้วย one-way ANOVA และ Tukey’s test รวมถึง Weibull regression เพื่อวิเคราะห์ความน่าจะเป็นของการอยู่รอด พบว่ากลุ่มที่มีความหนาเนื้อฟัน 1.5 มม. มีความทนต่อแรงแตกหักต่ำกว่ากลุ่มควบคุมและกลุ่มที่มีความหนา 2.0 มม. อย่างมีนัยสำคัญ พบการแตกของรากในแนวเฉียงในตัวอย่างทั้งหมด สำหรับกลุ่มเดือยฟันเสริมเส้นใย พบการแตกบ่อยที่บริเวณรอยต่อระหว่างเอ็มทีเอกับเดือยฟัน ขณะที่กลุ่มเรซินคอมโพสิตชนิดบ่มตัวร่วมมีค่าความทนต่อแรงแตกหักและความน่าจะเป็นในการอยู่รอดใกล้เคียงกับกลุ่มควบคุมที่มีรากฟันสมบูรณ์ ดังนั้นภายใต้ขอบเขตของการศึกษานี้ พบว่าสามารถใช้เรซินคอมโพสิตแบบบ่มตัวร่วมในการเสริมความแข็งแรงของฟันที่ได้รับการเหนี่ยวนำให้ปลายรากฟันปิดด้วยเอ็มทีเอได้อย่างมีประสิทธิภาพ
การเพาะเลี้ยงเซลล์ 3 มิติด้วยแม่เหล็กของเซลล์ต้นกำเนิดจากเซลล์เนื้อเยื่อในฟันมนุษย์และศักยภาพในการนำไปใช้ในทันตกรรมฟื้นฟู, นิก้า จอร์เจีย ซาลาซ่าร์
การเพาะเลี้ยงเซลล์ 3 มิติด้วยแม่เหล็กของเซลล์ต้นกำเนิดจากเซลล์เนื้อเยื่อในฟันมนุษย์และศักยภาพในการนำไปใช้ในทันตกรรมฟื้นฟู, นิก้า จอร์เจีย ซาลาซ่าร์
Chulalongkorn University Theses and Dissertations (Chula ETD)
การศึกษานี้พัฒนาระบบไฮโดรเจลอัลจิเนตที่ถูกออกซิไดซ์ เพื่อส่งผ่านปัจจัยกระตุ้นการเจริญของเซลล์ประสาททั้งแบบต่อเนื่องและทางอ้อม เพื่อส่งเสริมการเปลี่ยนแปลงไปเป็นเซลล์ประสาทของสเต็มเซลล์ที่ได้จากจากเนื้อเยื่อในฟันของมนุษย์ โดยได้ทำการวิเคราะห์ลักษณะของไฮโดรเจลในด้านระดับการออกซิไดซ์ การดูดซับน้ำ การย่อยสลาย และการปลดปล่อยโปรตีน ผลแสดงให้เห็นถึงการปลดปล่อยโปรตีนต้นแบบและ ปัจจัยกระตุ้นการเจริญของเซลล์ประสาทได้ตามช่วงเวลา ในการเพาะเลี้ยงเซลล์แบบ สองมิติ การร่วมเลี้ยงแบบทางอ้อมกับไฮโดรเจลที่พัฒนา พบว่าการแสดงออกของยีนและโปรตีนของตัวบ่งชี้เซลล์ประสาท (เนสติน, ดีซีเอกซ์และ เบต้าทรี ทุบูลิน) เพิ่มขึ้นอย่างมีนัยสำคัญ ความมีชีวิตของเซลล์ยังคงสูงตลอดการทดลอง แสดงถึงความเข้ากันได้ทางชีวภาพของไฮโดรเจลนี้ สำหรับการเปลี่ยนแปลงเป็นเซลล์ประสาทในระบบ สามมิติ ได้มีการสร้างสเฟียร์รอยด์ที่มีชีวิตและมีโครงสร้างแน่นหนาสำเร็จด้วยเทคนิค การปรินต์สามมิติด้วยแม่เหล็กผลการทดลองพบว่าสเฟียร์รอยด์ที่ใช้จำนวน10,000 เซลล์จะมีรูปร่างและความมีชีวิตที่เหมาะสมที่สุด นอกจากนี้ผลการทดลองปัจจุบันแสดงให้เห็นว่ามีศักยภาพของไฮโดรเจลในฐานะเป็นแพลตฟอร์มในการส่งผ่านโปรตีนเพื่อกระตุ้นการพัฬนาไปเป็นเซลล์ประสาทโดย ไม่ต้องใช้โครงร่างและสนับสนุนการประยุกต์ใช้งานในอนาคตกับงานวิจัยสเต็มเซลล์ระดับสามมิติและในระดับคลินิกในเชิงเวชศาสตร์ฟื้นฟูในสาขาทันตกรรมเอนโดดอนต์
The Comparison Of Learning Outcome Between Implant Placement Training With Xguide Vs Iris100 Navigation In Different Anatomical Situations, Supichaya Thanasanpaiboon
The Comparison Of Learning Outcome Between Implant Placement Training With Xguide Vs Iris100 Navigation In Different Anatomical Situations, Supichaya Thanasanpaiboon
Chulalongkorn University Theses and Dissertations (Chula ETD)
This study aimed to evaluate the learning outcomes, accuracy, efficiency, and user perceptions of two dynamic navigation systems, X-Guide and IRIS-100, in implant placement training for novice dentists across varying anatomical complexities.Fourteen novice dentists were initially recruited, with 12 completing the full training program. Participants underwent implant placement training on models representing straightforward and advanced cases using two training sequences: X-Guide followed by IRIS-100, and IRIS-100 followed by X-Guide. Accuracy was assessed by measuring angular, coronal, and apical deviations, as well as operation time, across pre-test, post-test 1, and post-test 2 phases using the freehand technique, followed by repeated measures …
Biological Effects Of Photobiomodulation On C2c12 Cell Culture Under Inflammatory Environment, Duong Le Dai
Biological Effects Of Photobiomodulation On C2c12 Cell Culture Under Inflammatory Environment, Duong Le Dai
Chulalongkorn University Theses and Dissertations (Chula ETD)
Backgrounds: In the last decade, photobiomodulation (PBM) has been utilized as a complementary therapeutic option for the management of musculoskeletal disorders such as temporomandibular disorders (TMD). However, its mechanism of action in skeletal muscle cells like the C2C12 myoblasts remains poorly understood. Thus, this study aimed to investigate the effects of PBM, using low-level light therapy (LLLT), on the proliferation and differentiation capacity of C2C12 cells cultured under normal media and compared with cells under proinflammatory environments. Materials and Methods: PBM treatment consisted of the following LLLT dose regimens: 1-day of 3, 5, and 7 J/cm2/day single doses and 2-day …
ความแตกต่างของความต้านทานความสึกของเฝือกสบฟันที่ใช้มุมการพิมพ์แบบสามมิติที่ต่างกัน, จรินทร์ทิพย์ สุวรรณบุตร
ความแตกต่างของความต้านทานความสึกของเฝือกสบฟันที่ใช้มุมการพิมพ์แบบสามมิติที่ต่างกัน, จรินทร์ทิพย์ สุวรรณบุตร
Chulalongkorn University Theses and Dissertations (Chula ETD)
เนื่องจากแนวโน้มในปัจจุบันของวัสดุทางทันตกรรมมุ่งเน้นไปที่การนำกระบวนการทางดิจิทัลมาใช้ในทางคลินิกอย่างเป็นรูปธรรม ตัวอย่างเช่น การใช้เทคโนโลยีการพิมพ์สามมิติในการผลิตอุปกรณ์ต่าง ๆ การศึกษาครั้งนี้จึงมุ่งเน้นการประเมินความทนต่อการสึกหรอของชิ้นงานที่ผลิตจากวัสดุสำหรับอุปกรณ์เฝือกสบฟัน (occlusal splint) โดยการพิมพ์สามมิติที่มุมการพิมพ์ต่างกัน เพื่อตรวจสอบมุมที่เหมาะสมที่สุดในการต้านทานการสึกหรอ เนื่องจากความทนต่อการสึกหรอและความแข็งของผิววัสดุเป็นปัจจัยสำคัญที่มีผลต่ออายุการใช้งานของอุปกรณ์เฝือกสบฟัน อย่างไรก็ตาม งานวิจัยที่ผ่านมาเกี่ยวกับการพิมพ์สามมิติมักมุ่งเน้นไปที่คุณสมบัติอื่น เช่น ความหยาบผิวขณะพิมพ์ (as-built surface roughness) หรือชนิดของวัสดุที่ใช้เป็นหลัก ดังนั้น การศึกษาครั้งนี้จึงให้ความสนใจในประเด็นดังกล่าว ตัวอย่างการทดลองจำนวน 6 ชิ้นต่อกลุ่มถูกสร้างขึ้นภายใต้ข้อกำหนดของมาตรฐาน ISO 14569-2 โดยชิ้นงานแต่ละชิ้นถูกกดด้วยเครื่องไฮดรอลิกด้วยแรงประมาณเท่ากับแรงบดเคี้ยวสูงสุดของผู้ป่วย bruxism (225 นิวตัน) ที่ความถี่ 1 เฮิรตซ์ จำนวน 840 ครั้ง ความหยาบผิวของชิ้นงานก่อนและหลังการทดสอบวัดด้วยเครื่องโปรฟิโลมิเตอร์แบบสัมผัส (contact profilometer) จากนั้นจึงทำการทดสอบความแข็งผิวด้วยเครื่องทดสอบไมโครฮาร์ดเนส (microhardness testing machine) ผลการทดลองแสดงให้เห็นว่าชิ้นงานที่พิมพ์ด้วยมุม 90 องศามีค่าความลึกของการสึกหรอต่ำที่สุด โดยค่าการสึกหรอเพิ่มขึ้นตามลำดับที่มุม 60, 30 และ 0 องศา ซึ่งมีความสัมพันธ์กับผลการทดสอบความแข็งของผิววัสดุ อย่างไรก็ตาม ในการนำผลการศึกษานี้ไปประยุกต์ใช้จริง ควรพิจารณาคุณสมบัติอื่น ๆ ที่อาจส่งผลต่อการใช้งานในแต่ละมุมการพิมพ์ร่วมด้วยอย่างรอบคอบ
Evaluation Of Cytotoxicity And Gene Expression Of Primary Human Periodontal Ligament Cells Against The Newly-Developed Bioceramic Sealer, Chanathip Chatphatthanasiri
Evaluation Of Cytotoxicity And Gene Expression Of Primary Human Periodontal Ligament Cells Against The Newly-Developed Bioceramic Sealer, Chanathip Chatphatthanasiri
Chulalongkorn University Theses and Dissertations (Chula ETD)
This study aimed to compare the biological properties of a newly developed cockle shell-derived bioceramic sealer (NDBS) with those of iRoot SP in relation to human periodontal ligament (hPDL) cells. NDBS was prepared according to previous study, and both sealers were extracted in complete medium and diluted into four concentrations (non-diluted, 1:2, 1:4, and 1:8). Biocompatibility testing followed ISO 7405 standards, using the MTT assay to assess cytotoxicity and proliferation at 1, 3, and 7 days. pro-inflammatory (IL-6, IL-8, TNF-α) and mineralization (ALP and OCN) gene expression analysis were performed using RT-qPCR on cells treated with 1:4 diluted extracts. MTT …
Inflammatory Responses Of Peri-Implant Crevicular Fluid On Different Dental Implant Abutment Materials After 6-Months Functional Loading: A Randomized Clinical Controlled Trial, Penkamol Wongrattanapasson
Inflammatory Responses Of Peri-Implant Crevicular Fluid On Different Dental Implant Abutment Materials After 6-Months Functional Loading: A Randomized Clinical Controlled Trial, Penkamol Wongrattanapasson
Chulalongkorn University Theses and Dissertations (Chula ETD)
Different abutment materials induce different immune responses in peri-implant soft tissues. Previous study showed that Ti base abutments without loading demonstrated comparable soft tissue-reaction to titanium abutments (Sampatanukul et al., 2018). Inflammatory responses after functional loading had not been elucidated in the previous study. This study investigates the inflammatory responses of peri-implant crevicular fluid around two abutment materials; titanium and titanium base (Ti base) after 6-months functional loading and identifies suitable abutment material which can induce stable inflammatory response in the peri-implant soft tissue. Sixteen implants of either Neodent or Straumann single implants were placed in sixteen patients in anterior …
Effects Of Fluocinolone Acetonide Treatment On Lps-Stimulated Human Dental Pulp Cells: An In Vitro Study, Supphachart Chayawatto
Effects Of Fluocinolone Acetonide Treatment On Lps-Stimulated Human Dental Pulp Cells: An In Vitro Study, Supphachart Chayawatto
Chulalongkorn University Theses and Dissertations (Chula ETD)
The inflammatory status of pulp tissue is one of the factors influencing the outcome of vital pulp therapy. Corticosteroids are well known for their anti-inflammatory properties and their role in promoting mineralization-related differentiation in human dental pulp cells (HDPCs). However, studies investigating the effects of corticosteroids under inflammatory conditions in HDPCs remain limited. This study aimed to compare the effect of fluocinolone acetonide (FA), mineral trioxide aggregate (MTA), and their combination on inflamed HDPCs, focusing on cell viability, expression of inflammatory and mineralization-related genes, and mineralization-related differentiation. HDPCs were treated with 20 µg/mL lipopolysaccharide (LPS) alone or in combination with …
Effect Of Different Surface Characterizations On Color Stability And Surface Roughness Of Provisional Materials After Toothbrushing, Sarasinee Sattawatthamrong
Effect Of Different Surface Characterizations On Color Stability And Surface Roughness Of Provisional Materials After Toothbrushing, Sarasinee Sattawatthamrong
Chulalongkorn University Theses and Dissertations (Chula ETD)
This study aimed to evaluate the surface roughness of 5 provisional materials with different surface characterization methods after simulating 1 year of toothbrushing. Specimens were fabricated from autopolymerized polymethyl methacrylate (UNIFAST Trad), autopolymerized bis-acryl composite resin (Protemp 4), light-activated composite resin (REVOTEK LC), milled polymethyl methacrylate block (DD provi P HI), and 3-dimensionally printed methacrylate oligomer (Nextdent C&B MFH). Each material was divided into 3 groups: polishing, application of Lite Art and Resin Glaze, and application of OPTIGLAZE color. After 5,000 and 10,000 toothbrushing cycles, surface roughness was measured. A 3-way repeated measures ANOVA was conducted to analyze the effects …
P2x7r And P2x4r Expression Of Mice Submandibular Gland In High‑Fat Diet/Streptozotocin‑Induced Type 2 Diabetes, Jiratchaya Srisutha
P2x7r And P2x4r Expression Of Mice Submandibular Gland In High‑Fat Diet/Streptozotocin‑Induced Type 2 Diabetes, Jiratchaya Srisutha
Chulalongkorn University Theses and Dissertations (Chula ETD)
Type 2 diabetes mellitus (T2DM) is a chronic inflammatory disease that can compromise the functioning of various organs, including the salivary glands (SG). The purinergic system is one of the most important inflammatory pathways in T2DM condition, and P2X7R and P2X4R are the primary purinergic receptors in SG that regulate inflammatory homeostasis. This study aimed to evaluate P2X7R and P2X4R expression, and morphological changes in the submandibular gland (SMG) in T2DM. Twenty‑four 5‑week‑old mice were randomly assigned to control (CON) and diabetes mellitus (DM) groups (n = 12 each). Body weight, diet, and blood glucose levels were monitored weekly. The …