Medicine and Health Sciences Commons^™

Ambulatory Electromyogram Activity In The Upper Trapezius Region: Patients With Muscle Pain Vs. Pain-Free Control Subjects, Charles R. Carlson, Kennen T. Wynn, John Edwards, Jeffrey P. Okeson, Arthur J. Nitz, Don E. Workman, Jeffrey Cassisi

CRVAW Faculty Journal Articles

Study Design: This study compared the ambulatory electromyogram activity of persons reporting pain in the shoulder and cervical regions with an equal group of persons not reporting such pain. Ambulatory electromyogram data were obtained over 3-day periods. In addition, all participants completed several standard psychological questionnaires.

Objectives: The results were analyzed with inferential statistics to determine whether subjects reporting significant pain in the shoulder and cervical regions had greater ambulatory electromyogram activity than an equal number of subjects not reporting pain.

Summary of Background Data: Considerable controversy exists regarding the role of muscle activity in the etiology and maintenance of …

Multidimensional Factors Affecting Well-Being: A Pni Based Model For Therapeutic Nursing Intervention., Mary P. Bennett

Nursing Faculty Publications

This paper is posted to assist graduate nursing students and others who are interested in my early PNI theory development work. The paper documents development and initial testing of a midrange theory of the effects of various nursing interventions on the psychoneuroimmunological (PNI) network. The hypothesized effects of interventions on various immune factors and subsequent health outcomes are explored, with special interest given to the use of PNI theory in nursing. More traditional nursing theory design principles are imbedded in this theory, including a definition of nursing and nursing intervention, as well as outlining how nurses educated at various levels …

Functioning And Well-Being Of Patients In A Consultation-Liaison Psychiatry Clinic, Steven A. Epstein, Junius Gonzales, Patricia Stockton, David M. Goldstein, Bonnie L. Green

Publications from Provost Junius J. Gonzales

Outpatient consultation-liaison (C-L) psychiatry clinics are valuable settings for research and teaching endeavors. However, little is known about psychiatric symptoms and health status of persons treated in such settings. In this study, 80 persons seen in an outpatient C-L psychiatry clinic were compared with 100 persons seen in a mood disorder clinic on a variety of self-report instruments. Outpatient C-L clinic patients were found to have significantly poorer health status than mood clinic patients on the following domains as measured by the RAND instrument: general health perception, pain, physical functioning, and role functioning due to physical problems. Both groups had …

Counseling And Testing For Hiv Prevention: Costs, Effects, And Cost-Effectiveness Of More Rapid Screening Tests, P. G. Farnham, Robin D. Gorsky, D. R. Holtgrave, Wanda K. Jones, Mary Guinan

Public Health Faculty Publications

New rapid human immunodeficiency virus (HIV) antibody tests permit many individuals to receive test results and appropriate counseling at one clinic visit. Because currently used tests require significant time for processing, all individuals must return for a second visit for test results and counseling. Since return rates for the second visit are low, the more rapid tests present an opportunity to improve the efficiency of HIV counseling and testing.

The authors compared the costs and effectiveness of the currently used counseling and testing procedure and a streamlined procedure made possible by the new, more rapid screening tests. When test-positive clients …

Preventing Perinatal Transmission Of Hiv Costs And Effectiveness Of A Recommended Intervention, Robin D. Gorsky, P G. Farnham, Walter L. Straus, Blake Caldwell, D R. Holtgrave, R. J. Simonds, M F. Rogers, Mary Guinan

Public Health Faculty Publications

In the United States, nearly all new human immunodeficiency virus (HIV) infections in children are acquired through perinatal (mother-to-infant) transmission. Each year, approximately 7000 infants are born to HIV-infected women in the United States.¹ Without intervention, an estimated 15-30% of these infants would become infected.² In 1994, results of the AIDS Clinical Trial Group (ACTG) Protocol 076 showed that treatment of infected pregnant women and their infants with zidovudine (ZDV) reduced the rate of perinatal HIV transmission from 25% to 8%.^3,4 Following these findings, the Public Health Service (PHS) issued recommendations for ZDV therapy to prevent perinatal …

Ventricular Remodeling Following Infant-Pediatric Cardiac Transplantation. Does Age At Transplantation Or Size Disparity Matter?, Girish S. Shirali, F Lombano, W L. Beeson, D A. Dyar, N F. Mulla, A Khan, J K. Johnston, R E. Chinnock, S R. Gundry, A J. Razzouk

Manuscripts, Articles, Book Chapters and Other Papers

Early left ventricular (LV) remodeling following pediatric cardiac transplantation has not been described. To identify patterns and determinants of change in left ventricular mass and volume posttransplant, we studied 125 consecutive children who underwent cardiac transplantation between January 1, 1989 and July 31, 1993. Two-dimensional imaging-directed M-mode echocardiograms were studied weekly until 26 weeks post-transplant. LV mass and volume (indexed to BSA1.5) were measured. LV mass index increased until 3 weeks post-transplant, and then decreased. The mean decrement in LV mass index after 8 weeks post-transplant (relative to baseline) was significantly larger in patients with donor-recipient weight ratio > 1.5 compared …

Evaluation Of Oral Midazolam As Pre-Medication In Day Care Surgery In Adult Pakistani Patients, N Ahmed, F A. Khan

Department of Anaesthesia

A placebo controlled randomized double blind study was designed to assess the suitability of oral Midazolam as a premedication in day care surgery in adult Pakistani patients. Fifty ASA I and II patients aged between 20-60 years received either Midazolam 7.5 mg or a placebo approximately one hour prior to surgery. Midazolam 7.5 mg produced significant anxiolysis and sedation (p < 0.001) in comparison to placebo after one hour of premedication. There was a significant difference (p < 0.001) in the mean heart rate and blood pressure in both groups after 1 hour of premedication with a lesser rise in blood pressure and heart rate in the Midazolam group. Psychomotor performance assessed by 'n' deletion test was impaired by Midazolam (p < 0.001) and recall of pictures revealed differences (p < 0.05) in the groups at one hour after premedication. However, at four hours after surgery there were no differences in both groups. These findings indicate that rapidly acting oral Midazolam in doses of 7.5 mg provided safe and effective premedication in terms of anxiolysis, sedation, amnesia and psychomotor performance and is suitable for day surgery.

Mental Disorders In Primary Care Services: An Update, Junius Gonzales, Kathryn M. Magruder, Samuel J. Keith

Publications from Provost Junius J. Gonzales

Frank mental disorders, such as depression and panic disorder, are prevalent in primary care; they cause people substantial suffering and interfere with daily functioning. Even subthreshold or "subsyndromal" conditions, with fewer symptoms than necessary for making a diagnosis, cause substantial morbidity. Recent literature on mental disorders in primary care, where many, if not most, people with mental health problems are seen, is reviewed with focus on recognition and diagnosis issues, management of these problems in primary care, obstacles to accurate diagnosis and appropriate treatment, and prevention issues. In addition to a review of recent research, there is an effort to …

An Unusual Reaction To Opioid Blockade With Naltrexone In A Case Of Posttraumatic Stress Disorder, Paloma Ibarra, Stephen P. Bruehl, James A. Mccubbin, Charles R. Carlson, John F. Wilson, Jane A. Norton, Thomas B. Montgomery

CRVAW Faculty Journal Articles

An unusual behavioral and cardiovascular reaction was observed during opioid blockade with naltrexone in a 32-year-old male who met DSM III-R criteria for post-traumatic stress disorder (PTSD). As part of an ongoing placebo-controlled investigation of the effects of naltrexone on laboratory and ambulatory blood pressure reactivity, this participant reported experiencing feelings of rage, explosive behavior, and other unpleasant symptoms. When compared to all other subjects (N=24), this individual showed significantly greater effects of naltrexone on blood pressure reactivity during the laboratory stressor. His ambulatory blood pressures, when compared to placebo, were significantly increased during the 24-hr period following …

Interaoperative Frozen Section Consultation: An Analysis Of Accuracy In A Teaching Hospital., Farrukh Aijaz, Suhail Muzaffar, Akbar Shah Hussainy, Shahid Pervez, Sheema H. Hasan, Hizbullah Sheikh

Department of Pathology and Laboratory Medicine

This Is a retrospective quality assurance study of all frozen sections done at The Aga Khan University Hospital during a six year period (1986 to 1991). There were 1,031 frozen sections out of a cumulative total of 42,985 surgical specimens (2.39%). Nine hundred and seventy-six (94.66%) were concordant. In 92(8.9%) fresh specimens were brought from other hospitals of Karachi, in 37 cases (3.58%) the diagnosis was deferred till the evaluation of permanent paraffin sections and 18 (1,74%) were discordant with 7 (0.67%) false positive and 11(1,06%) false negative. Among the discordant cases, 9 were attributed to misinterpretation, 7 due to …

Tracking Plasma Lactate Concentration In Vivo With A Catheter-Tip L-Lactate Sensor, Brett T. Weinzapfel, Mark D. Ball, Lee R. Waite, Nacer E. Abrouk, Shun P. Lim

Mathematical Sciences Technical Reports (MSTR)

To circumvent the problems of repeated blood sampling for in vitro analysis, a catheter-tip L-lactate sensor has been developed. The sensor was tested in anesthetized pigs (n=6). The sensor in vivo tracked the lactate concentration non-linearly, seeming to obey Michaelis-Menten kinetics. Calibration time was short, typically 1.5 min per lactate standard. Furthermore, time drift was small, typically -1.3% to -3.3% per hour of in vivo use.

Improved Recovery Of A Radlolabeled Peptide With An Albumin-Treated Reversed-Phase Hplc Column, David S. Hage, Robert L. Taylor, Pai C. Kao

David Hage Publications

Reversed-phase high-performance liquid chromatography (RP-HPLC) is an important tool in the purification of radiolabeled peptides and proteins for immunoassay. However, for some proteins and peptides it is difficult to achieve reproducible behavior in RP-HPLC because of the low recovery of these compounds. Factors that can be varied to improve recovery include the strength or pH of the mobile phase, the chain length and spacing of groups on the reversed-phase support, and the flow rate or steepness of the elution gradient (1-5). ... In summary, we obtained better recovery and more reproducible chromatographic behavior for labeled 1-34 PTHrP with an albumin-pretreated …

Intact Parathyroid Hormone: Performance And Clinical Utility Of An Automated Assay Based On High-Performance Immunoaffinity Chromatography And Chemiluminescence Detection, David S. Hage, Bob Taylor, Pai C. Kao

David Hage Publications

The performance and clinical utility of an automated assay of intact parathyroid hormone (parathyrin, PTH) are evaluated. The method is based on the extraction of PTH from plasma by an HPLC column containing immobilized anti-(44-68 PTH) antibodies. The PTH retained is detected with a postcolumn reactor and use of anti-(1--34 PTH) chemiluminescent-labeled antibodies. The total cycle time of the assay is 6.5 mm per injection after a 1-h incubation.The lower limit of detection for PTH in a 66-pL plasma sample was 0.5 pmol/L based on peak heights and 0.2 pmol/L based on peak areas. Mean analytical recovery for PTH added …

An In Vitro Evaluation Of Commercially Available Disposable Prophylaxis Angles, Caren M. Barnes, Lisa S. Fleming, Carl M. Russell

College of Dentistry: Faculty Publications

Although a number of manufacturers are marketing disposable prophylaxis angles, no literature exists regarding the mechanical efficacy and efficiency of these products. It was the purpose of this in vitro evaluation to compare and evaluate five brands of commercially available disposable prophylaxis angles for vibration, noise, heat rise, and torque. Random samples of each brand of disposable prophylaxis angle were utilized. Vibration was measured with a height gauge and running motor; noise was measured with a sound meter and heat rise was measured from 68°F on the head and body of the disposable prophylaxis angles, and torque required to destroy …

An In Vivo Comparison Of Commercially Available Disposable Prophylaxis Angles, Lisa S. Fleming, Caren M. Barnes, Carl M. Russell

College of Dentistry: Faculty Publications

A wide variety of disposable infection control products is being marketed including disposable prophylaxis angles. It was the purpose of this in vivo investigation to evaluate the clinical efficacy of five different brands of commercially available disposable prophylaxis angles. Utilizing a splitmouth design. 11 dental hygienists evaluated disposable prophylaxis angles while completing a routine oral prophylaxis. Fifty samples each of Brahler. Ash/Dentsply, Denticator. and Young Dental angles were compared to a control angle (Teledyne Getz). A questionnaire was completed by each operator following patient treatment (a total of 161 patients was treated). The questionnaire asked questions in which the four …

The Management Of Aerosols With Airpolishing Delivery Systems, Caren M. Barnes

College of Dentistry: Faculty Publications

In summary. aerosol production is inherent with airpolishers. as well as other dental equipment such as handpieces, ultrasonic scalers, and air/water syringes. By practicing prudent infection control techniques and utilizing proper operating techniques, the clinician can continue to enjoy the time-efficient and efficacious benefits of airpolishers, while ensuring a maximum protection from aerosols for the patient and the operator.

The Effects Of Suxamethonium And Pancuronium On The Haemodynamic Response To Endotracheal Intubation, F A. Khan, R S. Kamal

Department of Anaesthesia

The pharmacological effects of suxamethonium and pancuronium on the cardiovascular system may vary and therefore alter the haemodynamic response to intubation. The arterial blood pressure, the heart rate and the rate pressure product were measured as parameters of haemodynamic change in forty adult ASA. I and II patients undergoing laryngoscopy and endotracheal intubation in a randomised controlled study. The patients were induced with either thiopentone/suxamethonium (Group A) or thiopentone/pancuronium (Group B). There was no significant difference between the groups on comparison of systolic and diastolic blood pressure changes. Pancuronium, however, caused a significantly higher rise in the heart rate after …

Aging And The Restructuring Of Precued Movements, Paul Amrhein, George Stelmach, Noreen Goggin

Department of Psychology Faculty Scholarship and Creative Works

A precue paradigm was used to examine the time it takes to restructure a planned motor response. Two groups of subjects, a young group, and an elderly group, performed an aiming task in which 75% of the trials involved no change of movement parameters. On remaining trials, subjects had to change one or more of the movement parameters. Elderly subjects had slower reaction times (RTs), movement times, and made more errors in both conditions. Elderly subjects had proportionally longer RTs overall, independent of restructuring a movement plan. Preparation of arm and direction also exhibited a proportional increase in RT. However, …

J.T.: A Case Of Mitral Valve Prolapse, F. Matthew Mihelic

Faculty Publications

No abstract provided.

Ua3/3 Health Clinic Report 1965, Wku President's Office

WKU Archives Records

WKU Health Clinic monthly reports for 1965 recording the number of physical exams, immunizations, illnesses, diseases and injuries treated

Ua3/3 Health Clinic Report, Wku President's Office

WKU Archives Records

WKU Health Clinic monthly reports for 1964 recording the number of physical exams, immunizations, illnesses, diseases and injuries treated.

Ua3/3 Health Clinic Report, Wku President's Office

WKU Archives Records

WKU Health Clinic monthly reports for 1962 recording the number of physical exams, immunizations, illnesses, diseases and injuries treated.

Ua3/3 Health Clinic Report 1961, Wku President's Office

WKU Archives Records

WKU Health Clinic monthly reports for 1961 recording the number of physical exams, immunizations, illnesses, diseases and injuries treated.

Ua3/3 Health Clinic Report 1960, Wku President's Office

WKU Archives Records

WKU Health Clinic monthly reports for 1960 recording the number of physical exams, immunizations, illnesses, diseases and injuries treated.

Ua3/3 Health Clinic Report, Wku President's Office

WKU Archives Records

WKU Health Clinic monthly reports for 1959 recording the number of physical exams, immunizations, illnesses, diseases and injuries treated.

Ua3/3 Health Clinic Report, Wku President's Office

WKU Archives Records

WKU Health Clinic monthly reports for 1958 recording the number of physical exams, immunizations, illnesses, diseases and injuries treated.

Ua3/3 Health Clinic Report 1956-57, Wku President's Office

WKU Archives Records

WKU Health Clinic report for July 1956 to July 1957 recording the number of physical exams, immunizations, illnesses, diseases and injuries treated.

Ua3/3 Health Clinic Report, Wku President's Office

WKU Archives Records

WKU Health Clinic monthly reports for 1957 recording the number of physical exams, immunizations, illnesses, diseases and injuries treated.

Mercy's Messenger January 1917, Katharine B. Richardson

Archives

Mercy's Messenger was a newsletter describing the work of The Children's Mercy Hospital and soliciting donations, frequently including stories of young patients. This issue features Dr. Richardson's appeal for funding for a research laboratory to seek cures or better diagnosis and treatment of childhood diseases.