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Animal Experimentation and Research Commons

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Full-Text Articles in Animal Experimentation and Research

A Longitudinal View Of Primate Life In Two American Laboratories, Jonathan Balcombe May 2014

A Longitudinal View Of Primate Life In Two American Laboratories, Jonathan Balcombe

Experimentation Collection

If representative of other facilities, our findings uncover serious welfare concerns for the wellbeing of primates kept in American research facilities. These animals face regular or chronic sources of pain and distress including noxious experimental and non‐experimental events and illness and injury; and severe and prolonged social disruptions. Pain relief is meager by comparison to that normally provided to humans, despite legislative requirements to minimize pain and distress and assume similarity to humans in terms of ability to experience pain and distress. Living environments are usually confinement indoors to a metal cage, often alone, and often with a minimum of …


Socialized Vs. Unsocialized Wolves (Canis Lupus) In Experimental Research, Harry Frank, Linda M. Hasselbach, Dawn M. Littleton Jan 1986

Socialized Vs. Unsocialized Wolves (Canis Lupus) In Experimental Research, Harry Frank, Linda M. Hasselbach, Dawn M. Littleton

Experimentation Collection

In the experimental setting human contact is both more frequent and more intimate than in observational research, and the issue therefore assumes even greater importance. The present paper discusses two experimental studies of wolf information processing, one of which was conducted with unsocialized animals and one of which was conducted with socialized animals, and examines the both the management and methodological consequences of these approaches.


Ethics, Welfare, And Laboratory Animal Management, David J. Allan, Judith K. Blackshaw Jan 1986

Ethics, Welfare, And Laboratory Animal Management, David J. Allan, Judith K. Blackshaw

Experimentation Collection

Animals have been used in medical research from as far back as 129-199 A.D. when Galen, a Greek medical scientist, used a pig for his experiments. In the sixteenth and seventeenth centuries, anatomical dissections were carried out on animals; Galvani used frogs in 1791 for his experiments and the Russian physiologist, Pavlov, carried out his famous dog experiments in the early 1900s. Since this time, large numbers of animals have been used in biomedical and other research. In 1963 the first edition of "The Guide for the Care and Use of Laboratory Animals" was published, and the United States Public …


The Potential Role Of Local Ethical Committees In The Moderation Of Experiments On Animals In Britain, D. P. Britt Jan 1983

The Potential Role Of Local Ethical Committees In The Moderation Of Experiments On Animals In Britain, D. P. Britt

Experimentation Collection

Scientists working with laboratory animals in Britain are made aware forcibly that a serious ethical dilemma surrounds the use of animals in experiments. Certain vociferous sections of the community press the issue on the attention of the general public and media sources tend to propagate views expressed by the most extreme parties, while neglecting coverage of mature, rational opinion. It is, perhaps no bad thing for the scientific community to be frequently reminded to take a responsible attitude to the use of animals but recent overt, even illegal, activity on the part of extremist animal protectionist groups has encouraged a …


Regulation Of Biomedical Research, Andrew N. Rowan Jan 1981

Regulation Of Biomedical Research, Andrew N. Rowan

Experimentation Collection

The idea of abolishing or simplifying government regulations has a large following in Washington at the moment. As Reagan and his minions start to prune the growth of the past twenty years, we must hope that they are able to distinguish between the healthy growth which provides needed support and the unnecessary growth which strangles necessary initiatives. However, there is one area where we need more regulation rather than less, namely, biomedical research. In calling for more regulation in biomedical research, I do not mean the imposition of outside controls by allegedly ignorant and insensitive bureaucrats (although I think some …


Live Animals In Car Crash Studies, Nancy Heneson Jan 1980

Live Animals In Car Crash Studies, Nancy Heneson

Experimentation Collection

The scientific rationale for using live animals in car crash studies proceeds from the argument that comparative biomedical and biomechanical data are needed to develop an instrumented dummy, or anthropomorphic test device, which will provide reliable, reproducible information for designing safe cars. The animal studies are thus not really ends in themselves, i.e., they do not supply data which can be readily applied to real situations. Instead, they contribute to a pool of information which is supposed to lead to the perfecting of an experimental subject (the instrumented dummy) which will eventually render the further use of Iive animals unnecessary.