Animal Experimentation and Research Commons^™

The Validity Of Animal Experiments In Medical Research, Gill Langley

Gill Langley, PhD

Other animals, such as mice, rats, rabbits, dogs and monkeys, are widely used as surrogates for humans in fundamental medical research. This involves creating disorders in animals by chemical, surgical or genetic means, with the aim of mimicking selected aspects of human illnesses. It is a truism that any model or surrogate is not identical to the target being modelled. So, in medical research, experiments using animals or cell cultures or even healthy volunteers instead of patients (being the target population with the target illness) will inevitably have limitations, although these will be greater or lesser depending on the model.

The Validity Of Animal Experiments In Medical Research, Gill Langley

Experimentation Collection

Other animals, such as mice, rats, rabbits, dogs and monkeys, are widely used as surrogates for humans in fundamental medical research. This involves creating disorders in animals by chemical, surgical or genetic means, with the aim of mimicking selected aspects of human illnesses.

It is a truism that any model or surrogate is not identical to the target being modelled. So, in medical research, experiments using animals or cell cultures or even healthy volunteers instead of patients (being the target population with the target illness) will inevitably have limitations, although these will be greater or lesser depending on the model.

The Cruel Deception, Robert Sharpe

Experimentation Collection

With new legislation to replace the Cruelty to Animals Act 1876 near at hand, the powerful vested interest groups whose profits and livelihood depend on laboratory animals are stepping up their campaigns to ensure the survival of vivisection. Have the benefits really been so great, and can vivisection achieve major advances in our present state of health?

History shows (McKeown 1979) that the real reasons for the dramatic increase in life expectancy since the middle of the last century are improvements in nutrition, living and working conditions, hygiene and sanitation, with medical measures only having a relatively marginal effect. The …

Regulation Of Biomedical Research, Andrew N. Rowan

Experimentation Collection

The idea of abolishing or simplifying government regulations has a large following in Washington at the moment. As Reagan and his minions start to prune the growth of the past twenty years, we must hope that they are able to distinguish between the healthy growth which provides needed support and the unnecessary growth which strangles necessary initiatives. However, there is one area where we need more regulation rather than less, namely, biomedical research. In calling for more regulation in biomedical research, I do not mean the imposition of outside controls by allegedly ignorant and insensitive bureaucrats (although I think some …