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Full-Text Articles in Animal Experimentation and Research

Interests And Harms In Primate Research, Nathan Nobis May 2009

Interests And Harms In Primate Research, Nathan Nobis

Experimentation Collection

The article discusses the moral issues on primate research in reference to the moral defenses by Sughrue and colleagues. It states that Sughrue and colleagues have claimed to provide equal examination of the primate stroke research's ethics. It mentions that the promise to straighten out a number of ethical arguments in favor and against primate research was not fulfilled. Several moral arguments are presented in response to Sughrue and colleagues' moral defense for animal experimentation.


Resolving Animal Distress And Pain: Principles And Examples Of Good Practice In Various Fields Of Research, Alicia Karas, Matthew C. Leach, Karl A. Andrutis, Kathleen Conlee, John P. Gluck, Andrew N. Rowan, Martin L. Stephens Jan 2009

Resolving Animal Distress And Pain: Principles And Examples Of Good Practice In Various Fields Of Research, Alicia Karas, Matthew C. Leach, Karl A. Andrutis, Kathleen Conlee, John P. Gluck, Andrew N. Rowan, Martin L. Stephens

Laboratory Experiments Collection

Pain and distress are central topics in legislation, regulations, and standards regarding the use of animals in research. However, in practice, pain has received greatly increased attention in recent years, while attention to distress has lagged far behind, especially for distress that is not induced by pain. A contributing factor is that there is less information readily available on distress, including practical information on its recognition, assessment and alleviation.

This chapter attempts to help fill that void by reversing the usual pattern and giving greater attention to distress than to pain. In addition, we also bypass the pain versus distress …


Measurement And Mitigation Of Laboratory Animal Distress Sources Of Distress In The Animal Laboratory, Larry Carbone Jan 2009

Measurement And Mitigation Of Laboratory Animal Distress Sources Of Distress In The Animal Laboratory, Larry Carbone

Laboratory Experiments Collection

Pain and distress differ, but overlap. For the purposes of this discussion, we will consider pain to involve nociceptive input of stimuli that are potentially tissue damaging, and that further include an unpleasant emotional component (Merskey and Bogduk 1994). Pain need not necessarily induce distress, as when an animal or human willingly undergoes some painful situation in order to achieve a desired reward. In that case, while the pain may be unpleasant, it is not so severe as to be intolerable. Likewise, there are many potential causes of distress that do not involve physical pain.