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Articles 1 - 7 of 7
Full-Text Articles in Physiology
Mechanistic Insight Into The Role Of Dietary Fibers And Short Chain Fatty Acids In The Regulation Of Metabolism And Inflammation In The Pig, Hui Yan
Open Access Dissertations
Dietary fiber is a diverse mixture of polysaccharides exerting multiple functions as it passes through the gastrointestinal tract (GIT). Besides the influence on nutrient digestibility, dietary fiber affects growth performance and host metabolism via modulation of gut microbial community structure and production of short chain fatty acids (SCFA). A series of in vivo experiments were conducted to determine the effects of dietary fiber on pig growth performance and gut microbial community as well as host metabolism. In the first study, a comparison between soluble and insoluble fibers was conducted in terms of pig growth, gut microbial structure and SCFA production …
Effect Of Oxygen-Limiting Tidal Conditions On Muscle Metabolism And Structure In The Giant Acorn Barnacle, Balanus Nubilus, Katie O. Grady
Effect Of Oxygen-Limiting Tidal Conditions On Muscle Metabolism And Structure In The Giant Acorn Barnacle, Balanus Nubilus, Katie O. Grady
Master's Theses
Crustacean muscle fibers are some of the largest cells in the animal kingdom, with fiber diameters in the giant acorn barnacle (Balanus nubilus) exceeding 3 mm. Sessile animals with extreme muscle sizes and that live in the hypoxia-inducing intertidal zone – like B. nubilus – represent ideal models for probing the effects of oxygen limitation on muscle cells. We investigated changes in metabolism and structure of B. nubilus muscle in response to: normoxic immersion, anoxic immersion, or air emersion, for acute (6h) or chronic (6h exposures twice daily for 2wks) time periods. Following exposure, we immediately measured hemolymph …
Elucidating The Role Of Mifs-Mifr Two-Component System In Regulating Pseudomonas Aeruginosa Pathogenicity, Gorakh Digambar Tatke
Elucidating The Role Of Mifs-Mifr Two-Component System In Regulating Pseudomonas Aeruginosa Pathogenicity, Gorakh Digambar Tatke
FIU Electronic Theses and Dissertations
Pseudomonas aeruginosa is a Gram-negative, metabolically versatile, opportunistic pathogen that exhibits a multitude of virulence factors, and is extraordinarily resistant to a gamut of clinically significant antibiotics. This ability is in part mediated by two-component systems (TCS) that play a crucial role in regulating virulence mechanisms, metabolism and antibiotic resistance. Our sequence analysis of the P. aeruginosa PAO1 genome revealed the presence of two open reading frames, mifS and mifR, which encodes putative TCS proteins, a histidine sensor kinase MifS and a response regulator MifR, respectively. This two-gene operon was found immediately upstream of the poxAB operon, where poxB encodes …
The Effect Of Transformed Escherichia Coli On The Mouse Intestine Microbiome: The Microbial Metabolic Enhancement Hypothesis, Bryar P. Kader
The Effect Of Transformed Escherichia Coli On The Mouse Intestine Microbiome: The Microbial Metabolic Enhancement Hypothesis, Bryar P. Kader
Senior Honors Theses
Metabolic disorders affect around thirty-four percent of the population in the United States. Among these disorders is lactose intolerance, which results from diminished production of the human lactase enzyme. This disorder and others like it are genetically determined and cannot be cured. However, the use of transformed bacteria implanted in the colon may provide a means by which the faulty pathway can be bypassed. To test whether transformed bacteria have the capability to aid in the digestion of normally indigestible compounds, a transformed strain of Escherichia coli overexpressing the beta-galactosidase enzyme encoded by the lacZ gene was colonized in the …
The Effects Of Fitness Level And Sex On Epoc Following High Intensity Interval And Moderate Intensity Aerobic Exercise, Rachel Lauren Simmons
The Effects Of Fitness Level And Sex On Epoc Following High Intensity Interval And Moderate Intensity Aerobic Exercise, Rachel Lauren Simmons
Human Movement Sciences Theses & Dissertations
In the past few years, much attention has been directed toward shorter-duration vigorous intensity aerobic exercise as opposed to longer-duration moderate intensity exercise. There is conflicting evidence as to whether vigorous exercise can result in a greater excess post-exercise oxygen consumption (EPOC) and thus more calories burned when compared to moderate continuous exercise performed for a longer duration. In addition, the literature contains a dearth of information isolating and investigating male and female response to these exercises, as well as fit and unfit subjects. The purpose of this study was to quantify EPOC following moderate intensity aerobic exercise (MOD) and …
The Role Of Hypoxia On Pyruvate Kinase M2, Mammalian Target Of Rapamycin, Mitochondrial Function, And Cell Invasion In The Trophoblast, Rebecca Lutz Kimball
The Role Of Hypoxia On Pyruvate Kinase M2, Mammalian Target Of Rapamycin, Mitochondrial Function, And Cell Invasion In The Trophoblast, Rebecca Lutz Kimball
Theses and Dissertations
This thesis will be organized into two chapters discussing the role of hypoxia in the human placenta. The goal of this thesis is to characterize pyruvate kinase M2, mammalian target of rapamycin, mitochondrial function, and cell invasion in hypoxic conditions in the trophoblast. Understanding the mechanisms of placental metabolism can lead to further treatments for placental diseases. Chapter one covers the background of intrauterine growth restriction, hypoxia, placental metabolism, and pyruvate kinase M2 (PKM2). Little is currently understood about the role of the mitochondria in placental diseases. Expression of PKM2, trophoblast cell invasion, and mitochondrial function is shown to be …
Effects Of Salinity And Ph Change On The Physiology Of An Estuarine Fish Species, Fundulus Heteroclitus Heteroclitus, Shauna M. Tietze
Effects Of Salinity And Ph Change On The Physiology Of An Estuarine Fish Species, Fundulus Heteroclitus Heteroclitus, Shauna M. Tietze
Electronic Theses and Dissertations
Sapelo Island, Georgia is a pristine environment characterized by many variable salt marsh habitats. Throughout the island, salinity ranges from freshwater to full strength seawater and acidity levels range from low pH (pH < 4.4) to above neutral (pH > 8). Fundulus heteroclitus (Mummichog) is a resident organism of the salt marsh environment that has evolved coping strategies to withstand fluctuations in temperature, salinity and pH. Field and laboratory studies have shown F. heteroclitus to exhibit broad tolerance of individual environmental stressors; however, there is limited information on their ability to handle multiple stressors simultaneously. The goal of this study was to determine if exposure to low …