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Articles 1 - 9 of 9
Full-Text Articles in Physiology
Women's Health: Optimal Nutrition Throughout The Lifecycle, Edith J M Feskens, Regan Bailey, Zulfiqar Ahmed Bhutta, Hans-Konrad Biesalski, Heather Eicher-Miller, Klaus Krämer, Wen-Harn Pan, James C. Griffiths
Women's Health: Optimal Nutrition Throughout The Lifecycle, Edith J M Feskens, Regan Bailey, Zulfiqar Ahmed Bhutta, Hans-Konrad Biesalski, Heather Eicher-Miller, Klaus Krämer, Wen-Harn Pan, James C. Griffiths
Department of Paediatrics and Child Health
Sex differences are an important consideration when researching and establishing policies for nutrition and optimal health. For women's health, there are important physiologic, neurologic, and hormonal distinctions throughout the lifecycle that impact nutritional needs. Distinct from those for men, these nutritional needs must be translated into appropriate nutrition policy that aims to not only avoid overt nutritional deficiency, but also to promote health and minimize risk for chronic disease. Through a series of webinars, scientific experts discussed the advances in the understanding of the unique nutritional needs, challenges and opportunities of the various life stages for women across the life …
Biology Of Exosomes And Their Microrna Cargos In Human And Bovine Milk, Amy Lynn Leiferman
Biology Of Exosomes And Their Microrna Cargos In Human And Bovine Milk, Amy Lynn Leiferman
College of Education and Human Sciences: Dissertations, Theses, and Student Research
Exosomes are small, cargo-containing vesicles secreted by cells to facilitate intercellular communication. Of exosome cargos, microRNAs are especially interesting because of their involvement in gene regulation. Recently, our lab has shown that exosomes and their microRNA cargo are absorbed through the diet and elicit effects exogenously. Human and animal milk contain exosomes, which may have implications in infant and adult nutrition. There is evidence that bovine milk exosomes enhance growth of murine C2C12 myotube cell cultures, but whether this translates to muscle in vivo is unknown. The USDA National Nutrient Database for Standard Reference is lacking up-to-date information about human …
The Transcriptional Regulation Of The Human Angiotensinogen Gene After High-Fat Diet Is Haplotype-Dependent: Novel Insights Into The Gene-Regulatory Networks And Implications For Human Hypertension, A Rana, S Jain, N Puri, M Kaw, N Sirianni, D Eren, Brahma Mopidevi, Anand Kumar
The Transcriptional Regulation Of The Human Angiotensinogen Gene After High-Fat Diet Is Haplotype-Dependent: Novel Insights Into The Gene-Regulatory Networks And Implications For Human Hypertension, A Rana, S Jain, N Puri, M Kaw, N Sirianni, D Eren, Brahma Mopidevi, Anand Kumar
NYMC Faculty Publications
Single nucleotide polymorphisms (SNPs) in the human angiotensinogen (hAGT) gene may modulate its transcription and affect the regulation of blood pressure via activation of the renin-angiotensin aldosterone system (RAAS). In this regard, we have identified polymorphisms in the 2.5 Kb promoter of the hAGT gene that form two haplotype (Hap) blocks: -6A/G (-1670A/G, -1562C/T, -1561T/C) and -217A/G (-532T/C, -793A/G, -1074T/C & -1178G/A). hAGT gene with Hap -6A/-217A (Hap I) is associated with increased blood pressure whereas, Hap -6G/-217G (Hap II) is associated with normal blood pressure in human subjects. Since RAAS over activity contributes to hypertension in obesity, we have …
Effects Of Prenatal Environment Are Revealed By Post-Natal Challenges: Embryonic Hormone Exposure, Adrenocortical Function And Food In Seabird Chicks, Z. Morgan Benowitz-Fredericks, Jannik Schultner, Alexander S. Kitaysky
Effects Of Prenatal Environment Are Revealed By Post-Natal Challenges: Embryonic Hormone Exposure, Adrenocortical Function And Food In Seabird Chicks, Z. Morgan Benowitz-Fredericks, Jannik Schultner, Alexander S. Kitaysky
Faculty Journal Articles
The interaction between prenatal environments and postnatal environments is an important source of phenotypic variability. We examined the ability of prenatal steroid exposure and postnatal energy restriction to explain adrenocortical function and fledging age in captive seabird chicks. We proposed and tested two hypotheses: (1) the strength of prenatal effects is attenuated by challenging postnatal environments (postnatal override) and (2) the strength of prenatal effects increases with the severity of postnatal challenges (postnatal reveal). We reared common murre (Uria aalge) chicks and measured prenatal exposure to corticosterone (CORT) and testosterone (T) from allantoic waste. Adrenocortical function was assessed after 10 …
Cannabinoid Receptor 2 Agonist Attenuates Pain Related Behavior In Rats With Chronic Alcohol/High Fat Diet Induced Pancreatitis, Liping Zhang, Robert H. Kline Iv, Terry A. Mcnearney, Michael P. Johnson, Karin Westlund High
Cannabinoid Receptor 2 Agonist Attenuates Pain Related Behavior In Rats With Chronic Alcohol/High Fat Diet Induced Pancreatitis, Liping Zhang, Robert H. Kline Iv, Terry A. Mcnearney, Michael P. Johnson, Karin Westlund High
Physiology Faculty Publications
BACKGROUND: Chronic Pancreatitis (CP) is a complex and multifactorial syndrome. Many contributing factors result in development of dysfunctional pain in a significant number of patients. Drugs developed to treat a variety of pain states fall short of providing effective analgesia for patients with chronic pancreatitis, often providing minimal to partial pain relief over time with significant side effects. Recently, availability of selective pharmacological tools has enabled great advances in our knowledge of the role of the cannabinoid receptors in pathophysiology. In particular, cannabinoid receptor 2 (CB2) has emerged as an attractive target for management of chronic pain, as demonstrated in …
Modeling The Influence Of Vitamin D Deficiency On Cigarette Smoke-Induced Emphysema, Mardi A. Crane-Godreau, Candice C. Black, Andrew J. Giustini, Tenzin Dechen, Jihan Ryu, James A. Jukosky, Hong-Kee Lee, Katherine Bessette, Nora R. Ratcliffe, P. Jack Hoopes, Steven Fiering, John A. Kelly, J. C. Leiter
Modeling The Influence Of Vitamin D Deficiency On Cigarette Smoke-Induced Emphysema, Mardi A. Crane-Godreau, Candice C. Black, Andrew J. Giustini, Tenzin Dechen, Jihan Ryu, James A. Jukosky, Hong-Kee Lee, Katherine Bessette, Nora R. Ratcliffe, P. Jack Hoopes, Steven Fiering, John A. Kelly, J. C. Leiter
Dartmouth Scholarship
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. While the primary risk factor for COPD is cigarette smoke exposure, vitamin D deficiency has been epidemiologically implicated as a factor in the progressive development of COPD-associated emphysema. Because of difficulties inherent to studies involving multiple risk factors in the progression of COPD in humans, we developed a murine model in which to study the separate and combined effects of vitamin D deficiency and cigarette smoke exposure. During a 16-week period, mice were exposed to one of four conditions, control diet breathing room air (CD-NS), control …
Notes On The Diet Of The Malay Civet (Viverra Tangalunga) And Other Civets In Logged And Unlogged Lowland Dipterocarp Rain Forests In Sabah, Borneo, Christina P. Colon, John B. Sugau
Notes On The Diet Of The Malay Civet (Viverra Tangalunga) And Other Civets In Logged And Unlogged Lowland Dipterocarp Rain Forests In Sabah, Borneo, Christina P. Colon, John B. Sugau
Publications and Research
Civet diets were examined in a logged and unlogged Bornean rain forest. Malay civets (Viverra tangalunga) consumed invertebrates, fruit, rodents, insectivores, birds, snakes and lizards, and appear to show preference for centipedes and scorpions. Other civet species consumed fruit, such as figs, Connarus sp. and Annona sp., particularly in the unlogged forest, but also consumed invertebrates and vertebrates. Reduced fruit consumption observed in the logged forest may be due to lower availability and may be offset by increased consumption of invertebrates. The increased overlap in diet between Malay civets and other civets in disturbed areas may lead to …
Short Communication: Relationship Between Body Growth And Mammary Development In Dairy Heifers, L F. Silva, M J. Vandehaar, Brian K. Whitlock, R P. Radcliff, H A. Tucker
Short Communication: Relationship Between Body Growth And Mammary Development In Dairy Heifers, L F. Silva, M J. Vandehaar, Brian K. Whitlock, R P. Radcliff, H A. Tucker
Faculty Publications and Other Works -- Large Animal Clinical Sciences
Our objective was to determine if prepubertal rate of body weight (BW) gain, independent of diet, was related to mammary development of dairy heifers. Data from two studies recently conducted at Michigan State University were used to identify factors, within a dietary treatment group, that would account for variation in first lactation milk production or amount of mammary parenchymal DNA at the time of puberty. Factors analyzed for variation in milk production during first lactation were: postpartum BW, prepubertal BW gain, gestational BW gain, postpartum BW gain, body condition score (BCS) at breeding, and BCS at calving. Factors analyzed for …
Rate Of Depletion Of Liver Vitamin A In Chicks, Weanling Rabbits And Weanling Rats Fed Vitamin A-Free Diets, J.J. Tlustohowicz, R.C. Hall, J.E. Rousseau, H.I. Frier, S. Donoghue
Rate Of Depletion Of Liver Vitamin A In Chicks, Weanling Rabbits And Weanling Rats Fed Vitamin A-Free Diets, J.J. Tlustohowicz, R.C. Hall, J.E. Rousseau, H.I. Frier, S. Donoghue
Storrs Agricultural Experiment Station
No abstract provided.