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Articles 1 - 13 of 13
Full-Text Articles in Physiology
Sarcopenia And The Importance Of Resistance Training And Protein-Rich Diets For Prevention Of Muscle Loss In Older Adults: A Literature Review And Informational Pamphlet, Madison Steele
Honors Theses
The growing prevalence of sarcopenia among older adults as well as youths has prompted further research aimed at developing effective preventative measures and treatment plans. Sarcopenia is often thought to occur solely due to aging, but several other factors contribute to progressive muscle loss. Previous research studies have found an effect of physical activity and dietary protein levels on the risk of developing sarcopenia as well as its onset age. This study aims to review existing knowledge in the field to compile an extensive list of sarcopenia causes and methods of prevention. The main causes identified in this review are …
The Effects Of Water Submersion On Skeletal Muscle Activation, Fatigue, And Whole-Body Gas Exchange, Caroline Griffin, Robert J. Shute
The Effects Of Water Submersion On Skeletal Muscle Activation, Fatigue, And Whole-Body Gas Exchange, Caroline Griffin, Robert J. Shute
Honors Projects
THE EFFECTS OF WATER SUBMERSION ON SKELETAL MUSCLE ACTIVATION, FATIGUE, AND WHOLE-BODY GAS EXCHANGE
C.C. Griffin. Bridgewater College, Bridgewater, VA.
Email: Cgriffin@eagles.bridgewater.edu
Fatigue of skeletal muscle can be affected by multiple environmental elements. Fatigue threshold can be measured by VO2 max on a cycle ergometer combined with the use of a metabolic cart and Electromyography (EMG) measurements. PURPOSE: The purpose of this experiment is to determine if water submersion affects skeletal muscle activation, fatigue, and whole-body gas exchange. METHODS: Three participants were recruited to participate in a cold and no temperature trial. Participants arrived and baseline vitals and measurements were …
Pathogenesis And Therapeutic Considerations For Nonalcoholic Fatty Liver Disease, Elijah Chung
Pathogenesis And Therapeutic Considerations For Nonalcoholic Fatty Liver Disease, Elijah Chung
Senior Honors Theses
A product of the Westernized, high-fat diet, non-alcoholic fatty liver disease (NAFLD) has emerged as the leading cause of chronic liver disease, affecting one-fourth of the world's population. NAFLD is a progressive disease arising from a multisystem response to excess lipids in the blood, adipose tissue, and liver. Despite the prevalence of NAFLD and its well-studied bidirectional association with obesity and type 2 diabetes mellitus and obesity, there is a shocking scarcity of available treatments aside from diet and lifestyle changes. Thus, further research on NAFLD and potential therapies is urgently needed. This paper will illustrate the major pathways associated …
Physiological Processes During Reading, Elizabeth Morrey, Emma Smith, Catherine Bohn-Gettler, Jennifer Schaefer
Physiological Processes During Reading, Elizabeth Morrey, Emma Smith, Catherine Bohn-Gettler, Jennifer Schaefer
Celebrating Scholarship and Creativity Day (2018-)
There are many different variables that can impact reading comprehension, such as reading level, emotional state, and the content of the text itself. For example, if a text contains inconsistencies (e.g., when a key moment in the text does not align with the information presented earlier in the story), processing slows as readers attempt to resolve the inconsistency. However, little is known about the connection between processing inconsistent versus consistent passages and physiological responses in the body. The goal of this study is to examine whether reading narrative texts containing inconsistent and/or consistent information elicits sympathetic nervous system activation, as …
Cortisol Production In Female Soccer Players, Katelyn Seagraves
Cortisol Production In Female Soccer Players, Katelyn Seagraves
ASPIRE 2024
Cortisol is released from the adrenal glands when there is an apparent stressor. Exercise, while beneficial, is seen as stress to the body and incites increased cortisol release. Cortisol is known to increase with exercise, and higher-intensity exercise tends to raise cortisol more compared to lower intensities. However, less is known about interval training and cortisol concentrations.
This review of literature dives into the background of cortisol: how it's produced, what systems it regulates, and differences in production based on gender, stressors, exercise intensity, and duration. This paper identifies some knowledge gaps and links training intensities in soccer to cortisol …
Cortisol Production In Female Soccer Players, Katelyn Seagraves
Cortisol Production In Female Soccer Players, Katelyn Seagraves
Honors Projects
Cortisol is released from the adrenal glands when there is an apparent stressor. Exercise, while beneficial, is seen as stress to the body and incites increased cortisol release. Cortisol is known to increase with exercise, and higher-intensity exercise tends to raise cortisol more compared to lower intensities. However, less is known about interval training and cortisol concentrations.
This review of literature dives into the background of cortisol: how it's produced, what systems it regulates, and differences in production based on gender, stressors, exercise intensity, and duration. This paper identifies some knowledge gaps and links training intensities in soccer to cortisol …
Health-Promoting Benefits Of Lentils: Anti-Inflammatory And Anti-Microbial Effects, Rachel Alexander, Abdullah Khaja, Nicholas Debiec, Alex Fazioli, Mary Torrance, Mohammed S. Razzaque
Health-Promoting Benefits Of Lentils: Anti-Inflammatory And Anti-Microbial Effects, Rachel Alexander, Abdullah Khaja, Nicholas Debiec, Alex Fazioli, Mary Torrance, Mohammed S. Razzaque
School of Medicine Publications and Presentations
This paper describes how lentils (Lens culinaris species) can positively affect health by reducing inflammation, providing antioxidants, and displaying antimicrobial properties. Lentils are rich in proteins, essential amino acids, minerals, and fibers, making them a valuable source of nutrition, particularly in low and middle-income countries. Lentils have many health benefits, including positive effects on diabetes management, support for cardiovascular health, and antioxidative properties. The antioxidative properties of lentils, attributed to their phenolic content, and their ability to inhibit inflammation-related enzymes are also discussed. We discuss the potential of lentils as a dietary tool in promoting immunity, reducing disease burdens, …
Effectiveness Of Probiotic Therapy On The Symptoms Of Major Depressive Disorder (Mdd), Lydia L.M. Sprague
Effectiveness Of Probiotic Therapy On The Symptoms Of Major Depressive Disorder (Mdd), Lydia L.M. Sprague
Non-Thesis Student Work
Major Depressive Disorder (MDD) represents a pervasive mental health challenge globally, necessitating effective treatment approaches. This paper examines the efficacy of probiotic therapy compared to placebo in individuals diagnosed with MDD, addressing the PICOT question: In people diagnosed with MDD, what effect does probiotic therapy versus placebo have on their symptoms of depression? Through a review of six randomized controlled trials (RCTs), the study elucidates the potential of probiotics as adjunctive treatments for MDD. Findings indicate that probiotic interventions may yield improvements in depression symptoms, reflecting promising avenues for complementary therapeutic strategies. However, variations in study designs and probiotic strains …
Editorial: Pharmacology Of Endocrine Related Gpcrs, Francesco De Pascali, Aylin Hanyaloglu, Frederic Jean-Alphonse, Francesco Potì, Eric Reiter
Editorial: Pharmacology Of Endocrine Related Gpcrs, Francesco De Pascali, Aylin Hanyaloglu, Frederic Jean-Alphonse, Francesco Potì, Eric Reiter
Department of Biochemistry and Molecular Biology Faculty Papers
No abstract provided.
Radiofrequency Ablation Of Thyroid Nodules: A Clinical Review Of Treatment Complications, Peter P. Issa, Katherine Cironi, Leely Rezvani, Emad Kandil
Radiofrequency Ablation Of Thyroid Nodules: A Clinical Review Of Treatment Complications, Peter P. Issa, Katherine Cironi, Leely Rezvani, Emad Kandil
School of Medicine Faculty Publications
Radiofrequency ablation (RFA) is a minimally invasive ablative modality for the treatment of thyroid nodules. Reports of RFA use have demonstrated an impressive safety profile and excellent volume reduction rates between 60-90%. Given its increased popularity in the United States as well as globally, numerous recent works have been published and a discussant of relevant complications incorporating recent insight may assist practitioners in minimizing complications and optimizing patient outcomes. Herein, we provide a comprehensive and updated review of the reported complications and side effects following RFA, summarizing their frequency and clinical presentation. We also describe a means of minimizing such …
Biol 225 - Laboratory Manual For Human Physiology, Corey Sullivan, Kristin Thurlby, Gwen Wright
Biol 225 - Laboratory Manual For Human Physiology, Corey Sullivan, Kristin Thurlby, Gwen Wright
Human Physiology
This laboratory manual for Human Physiology represents the Creative Commons licensed (CC-BY-NC 4.0) material created as an Open Educational Resource.
Activation Of Renal Epithelial Na+ Channels (Enac) In Infants With Congenital Heart Disease, Laura Ortmann, Shyam Sundar Nandi, Yulong Li, Hong Zheng, Kaushik K. Patel
Activation Of Renal Epithelial Na+ Channels (Enac) In Infants With Congenital Heart Disease, Laura Ortmann, Shyam Sundar Nandi, Yulong Li, Hong Zheng, Kaushik K. Patel
Journal Articles: Cellular & Integrative Physiology
INTRODUCTION: This study was designed to measure the concentration and activity of urinary proteases that activate renal epithelial sodium channel (ENaC) mediated Na
METHODS: Urine samples from infants undergoing cardiac surgery were collected at three time points: T1) pre-operatively, T2) 6-8 h after surgery, and T3) 24 h after diuretics. Urine was collected from five heathy infant controls. The urine was tested for four proteases and whole-cell patch-clamp testing was conducted in renal collecting duct M-1 cells to test whether patient urine increased Na
RESULTS: Heavy chain of plasminogen, furin, and prostasin were significantly higher in cardiac patients prior to …
Innate And Adaptive Immune System Consequences Of Post-Traumatic Stress Disorder, Tatlock H. Lauten, Tamara Natour, Adam J. Case
Innate And Adaptive Immune System Consequences Of Post-Traumatic Stress Disorder, Tatlock H. Lauten, Tamara Natour, Adam J. Case
Journal Articles: Cellular & Integrative Physiology
In the field of psychiatry, biological markers are rarely, if ever, used in the diagnosis of mental health disorders. Clinicians rely primarily on patient histories and behavioral symptoms to identify specific psychopathologies, which makes diagnosis highly subjective. Moreover, therapies for mental health disorders are aimed specifically at attenuating behavioral manifestations, which overlooks the pathophysiological indices of the disease. This is highly evident in posttraumatic stress disorder (PTSD) where inflammation and immune system perturbations are becoming increasingly described. Further, patients with PTSD possess significantly elevated risks of developing comorbid inflammatory diseases such as autoimmune and cardiovascular diseases, which are likely linked …