Physiology Commons^™

Hemodynamics And Arterial Stiffness In Response To Oral Glucose Loading In Individuals With Type Ii Diabetes And Controlled Hypertension, Yu Lun Tai, Smaran Marupudi, Gabriel A. Figueroa, Ryan D. Russell

Health & Human Performance Faculty Publications and Presentations

Introduction: Type 2 diabetes (T2D), the fastest growing pandemic, is typically accompanied by vascular complications. A central hallmark of both T2D and vascular disease is insulin resistance which causes impaired glucose transport and vasoconstriction concomitantly. Those with cardiometabolic disease display greater variation in central hemodynamics and arterial elasticity, both potent predictors of cardiovascular morbidity and mortality, which may be exacerbated by concomitant hyperglycemia and hyperinsulinemia during glucose testing. Thus, elucidating central and arterial responses to glucose testing in those with T2D may identify acute vascular pathophysiologies triggered by oral glucose loading.

Aim: This study compared hemodynamics and arterial stiffness to …