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Full-Text Articles in Physiology

A Carboxyl-Terminal Sequence In The Lutropin Β Subunit Contributes To The Sorting Of Lutropin To The Regulated Pathway, Albina Jablonka-Shariff, Christopher A. Pearl, Anna Comstock, Irving Boime Apr 2008

A Carboxyl-Terminal Sequence In The Lutropin Β Subunit Contributes To The Sorting Of Lutropin To The Regulated Pathway, Albina Jablonka-Shariff, Christopher A. Pearl, Anna Comstock, Irving Boime

Peer Reviewed Articles

Although synthesized in the same pituitary gonadotropes, the secretion profiles of lutropin (LH) and follitropin (FSH) differ. LH is secreted through a regulated pathway and associated with a bolus release at mid-estrous cycle. In contrast, the majority of FSH is secreted constitutively with an incremental increase until ovulation. Both share an identicalα subunit, and thus theβ subunit contains determinants for sorting into the regulated pathway. Previously, we demonstrated that a hydrophobic carboxyl-terminal heptapeptide of the LHβ subunit (Leu-Ser-Gly-Leu-Leu-Phe-Leu), not found in the FSHβ subunit, influences the intracellular behavior of the LH dimer. To test the hypothesis that the peptide contributes …


Determination Of Energy Expenditure During Pregnancy And Its Comparison To The Compendium Of Physical Activity Values: A Pilot Study, Laura K. Dahmer, Dawn Podulka Coe, Brian Hatzel Jan 2008

Determination Of Energy Expenditure During Pregnancy And Its Comparison To The Compendium Of Physical Activity Values: A Pilot Study, Laura K. Dahmer, Dawn Podulka Coe, Brian Hatzel

Student Summer Scholars Manuscripts

Current exercises recommended during pregnancy are prescribed at the same intensity as the general adult population, 3-6 METs. It is unclear whether these MET values can be applied to the pregnant population. Purpose: To determine energy expenditure of pregnant women while participating in three exercises (walking, stationary biking, and prenatal aerobics) during the second and third trimesters. And second, to determine whether the energy expenditure of the exercises would change from the second to third trimester. Methods: Participants were 3 women, ages 23-32, in their second trimester (weeks 14-26) of pregnancy at commencement of the study. Subjects reported to the …