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The Use Of Forelimb Asymmetry Functional Tests To Determine Motor Recovery With Various Drug Treatments Following Endothelin-Induced Stroke, Kelly Rebecca Leach
The Use Of Forelimb Asymmetry Functional Tests To Determine Motor Recovery With Various Drug Treatments Following Endothelin-Induced Stroke, Kelly Rebecca Leach
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Our laboratory has found increased functional recovery post-stroke with Long Evans rats that received a combination of fluoxetine, simvastatin, and vitamin C. The objectives of this study were to test that treatment and other drug combinations on Sprague Dawley rats, to determine whether Forelimb Asymmetry is a reliable behavioral measure for stroke studies, and to determine the most optimal surgical procedure on Sprague Dawley rats. There were more significant increases in functional recovery observed on the Forelimb Asymmetry than on Montoya Staircase behavioral tests, but there were no significant differences between treatment groups and control. The largest number of rats …