Physiology Commons^™

Potential Health Risks Linked To Emerging Contaminants In Major Rivers And Treated Waters, James Kessler, Diane Dawley, Daniel Crow, Ramin Garmany, Philippe T. Georgel

Biological Sciences Faculty Research

The presence of endocrine-disrupting chemicals (EDCs) in our local waterways is becoming an increasing threat to the surrounding population. These compounds and their degradation products (found in pesticides, herbicides, and plastic waste) are known to interfere with a range of biological functions from reproduction to differentiation. To better understand these effects, we used an in silico ontological pathway analysis to identify the genes affected by the most commonly detected EDCs in large river water supplies, which we grouped together based on four common functions: Organismal injuries, cell death, cancer, and behavior. In addition to EDCs, we included the opioid buprenorphine …