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Full-Text Articles in Physiology
Comparison Of Effects Of Sleep Fragmentation On Pro-Inflammatory Cytokine Il-1Β Of Male And Female Adult Mice, Manzar Rzayeva
Comparison Of Effects Of Sleep Fragmentation On Pro-Inflammatory Cytokine Il-1Β Of Male And Female Adult Mice, Manzar Rzayeva
Mahurin Honors College Capstone Experience/Thesis Projects
Sleep plays an essential role throughout the body by affecting the physiological function and regulation of many systems. One of these systems that receives effects as a result of the adequacy of sleep is the immune system. Previous studies have demonstrated effects of sleep fragmentation upon the immune system; however, sexual differences of these effects have not been studied in depth. To analyze these variances amongst the genders, male and female adult mice were subjected to acute sleep fragmentation (SF) for 24 hours in an automated SF cage that includes a bar sweeping across the cage every two minutes. Meanwhile, …
Effect Of Acute Sleep Fragmentation Upon Inflammatory Response Of Brown And White Adipose Tissue In Male Mice, Zach Wriedt
Effect Of Acute Sleep Fragmentation Upon Inflammatory Response Of Brown And White Adipose Tissue In Male Mice, Zach Wriedt
Mahurin Honors College Capstone Experience/Thesis Projects
Sleep is an important process required for vertebrates, including humans, to function. When sleep is disrupted, it leads to deleterious effects such as inflammatory responses throughout the body. Past studies have shown that acute (24 h) sleep fragmentation (SF) leads to an inflammatory response in white adipose tissue. However, whether brown adipose tissue responds in a similar fashion is unknown. Male adult (>8 weeks of age) C57BL/6j mice were subjected to SF for 24 h using a cage outfitted with a bar that moves horizontally across the cage every 2 min to periodically awaken mice (N =10). Controls were …