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Acute And Chronic Effects Of Artificial Rearing On Rat Genioglossus Muscle, Wayne Allen Moore Jr. Jan 2005

Acute And Chronic Effects Of Artificial Rearing On Rat Genioglossus Muscle, Wayne Allen Moore Jr.

Theses and Dissertations

In most mammals, nutritive suckling is critical during the early neonatal period. The genioglossus (GG) muscle in rat plays an important role in protruding the tongue for efficient suckling. The purpose of this study was to examine the contractile properties and myosin heavy chain (MHC) phenotype of the GG following an early period of artificial rearing, which reduced nutritive suckling. Beginning at three days of age Sprague-Dawley rats were fed via implanted gastric cannula until postnatal day 14 (P14). At P14, artificially reared (AR) rat pups were either placed with a lactating dam until the end of the weaning period …