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Full-Text Articles in Physiology
Elucidating The Role Of Mifs-Mifr Two-Component System In Regulating Pseudomonas Aeruginosa Pathogenicity, Gorakh Digambar Tatke
Elucidating The Role Of Mifs-Mifr Two-Component System In Regulating Pseudomonas Aeruginosa Pathogenicity, Gorakh Digambar Tatke
FIU Electronic Theses and Dissertations
Pseudomonas aeruginosa is a Gram-negative, metabolically versatile, opportunistic pathogen that exhibits a multitude of virulence factors, and is extraordinarily resistant to a gamut of clinically significant antibiotics. This ability is in part mediated by two-component systems (TCS) that play a crucial role in regulating virulence mechanisms, metabolism and antibiotic resistance. Our sequence analysis of the P. aeruginosa PAO1 genome revealed the presence of two open reading frames, mifS and mifR, which encodes putative TCS proteins, a histidine sensor kinase MifS and a response regulator MifR, respectively. This two-gene operon was found immediately upstream of the poxAB operon, where poxB encodes …
The Individual And Interactive Effects Of Nitrogen And Phosphorus Enrichment On Coral Reefs, Andrew A. Shantz
The Individual And Interactive Effects Of Nitrogen And Phosphorus Enrichment On Coral Reefs, Andrew A. Shantz
FIU Electronic Theses and Dissertations
Human domination of global nutrient cycles is profoundly altering our planet. Yet on coral reefs, the effects of changing nutrient regimes have likely been over-simplified. This dissertation investigates the complexity of animal-nutrient interactions at the organismal level and explores how the outcomes of these interactions cascade through levels of biological organization. To do so, I examined the effects of nitrogen (N) and phosphorus (P) on corals and macroalgae, and how these effects in turn influenced reef communities and entire ecosystems. I show that P consistently increases coral growth rates while N has variable, often negative, effects on coral growth. The …