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Full-Text Articles in Physiology

Motor Cortex Electrical Stimulation Augments Sprouting Of The Corticospinal Tract And Promotes Recovery Of Motor Function, Jason B. Carmel, John H. Martin Jun 2014

Motor Cortex Electrical Stimulation Augments Sprouting Of The Corticospinal Tract And Promotes Recovery Of Motor Function, Jason B. Carmel, John H. Martin

Publications and Research

The corticospinal system—with its direct spinal pathway, the corticospinal tract (CST) – is the primary system for controlling voluntary movement. Our approach to CST repair after injury in mature animals was informed by our finding that activity drives establishment of connections with spinal cord circuits during postnatal development. After incomplete injury in maturity, spared CST circuits sprout, and partially restore lost function. Our approach harnesses activity to augment this injury-dependent CST sprouting and to promote function. Lesion of the medullary pyramid unilaterally eliminates all CST axons from one hemisphere and allows examination of CST sprouting from the unaffected hemisphere. We …


Combination Therapy Of Hyaluronic Acid Mesotherapic Injections And Sclerotherapy For Treatment Of Lower Leg Telangiectasia Without Major Venous Insufficiency: A Preliminary Clinical Study, Tommaso Iannitti, Valentina Rottigni, Federica Torricelli, Beniamino Palmieri Apr 2014

Combination Therapy Of Hyaluronic Acid Mesotherapic Injections And Sclerotherapy For Treatment Of Lower Leg Telangiectasia Without Major Venous Insufficiency: A Preliminary Clinical Study, Tommaso Iannitti, Valentina Rottigni, Federica Torricelli, Beniamino Palmieri

Physiology Faculty Publications

Background. Telangiectasia is the dilation of dermal capillaries mainly due to hypertension and vein insufficiency. Treatments of choice for this condition are sclerotherapy with foam liquid or intradermal fiber optic laser energy delivery. Aim. The aim of this study was to assess the efficacy of a new therapeutic approach consisting in the use of polymerized hyaluronic acid mesotherapicinjections following sclerotherapy in the areas of the skin affected by telangiectasia in patients without major vein insufficiency. Materials and Methods. A total of 20 women, aged between 19 and 64 years, affected by recurrent lower leg telangiectasia, were included in this study. …