Physiology Commons^™

Chronic Hypoxia, Exercise Training, And Skeletal Muscle Capillarity: Angiogenic Regulation And Morphological Consequences, Ivan Mark Olfert

Loma Linda University Electronic Theses, Dissertations & Projects

Angiogenesis is important in health and disease. In particular, exercise training is known to increase skeletal muscle capillarity, providing there is sufficient training intensity. The stimulus for this may be intracellular hypoxia activating angiogenic growth factor gene expression. Acute hypoxia alone has been shown to increase the gene expression of several key angiogenic regulators, e.g. vascular endothelial growth factor (VEGF) and to a lesser degree transforming growth factor-β1 (TGF-β1), basic fibroblast growth factor (bFGF), and thrombospondin-1 (TSP-1), an endogenous negative angiogenic regulator. Paradoxically, however, chronic hypoxia is generally not found to increase mammalian skeletal muscle capillarity. Accordingly, we hypothesized that …

The Affect Of Low Intensity, Progressive, Aerobic Exercise Training On Cardiovascular Function In The Diabetic Rat, Steven Michael Bauer

Morehead State Theses and Dissertations

A thesis presented to the faculty of the College of Science and Technology at Morehead State University in partial fulfillment of the requirements for the Degree of Masters of Science in Biology by Steven Michael Bauer on August 4, 2000.

Recycling Of Deuterium From Dideuterated Glucose During Moderate Exercise, Michael A. Horning, Sheri R. Colberg, Gretchen A. Casazza, George A. Brooks

Educational Foundations & Leadership Faculty Publications

A doubly labelled tracer molecule of glucose, [6,6^-2HJglucose, has been used to measure the rate of glucose appearance in blood due to endogenous glucose production (by the liver and kidneysj.^l,2 Considered 'non-recirculating', this tracer generally provides a realistic estimate of glucose kinetics.^2,3 Used as a dual tracer in conjunction with [l-¹³C]glucose, the extent of glucose recycling can be quantitated.^2-4 but the extent of possible recirculation of a single deuterium atom on newly formed glucose must then be considered.

The Effect Of Two States Of Hydration On Muscular Endurance In Men, Melissa L. Petrucci

Masters Theses

The purpose of this study was to investigate the effects of two states of hydration has an effect on muscular endurance in men. Two groups of four men randomly assigned to each group participated in both states of hydration. Both groups were tested at baseline for height, weight, intra- and extra-cellular water, total body water, and a one-repetition maximum strength test. Subjects were then tested after a 24 hour period of water deprivation, and after a 24 hour period of normal water intake (8 ten oz glasses of water). A urine specific gravity test, intra- and extra-cellular water, total body …

Client-Centered Versus Traditional-Directive Educational Approach: A Randomized Study Of Exercises And Perceived Control Among Patients With Type 2 Diabetes, Melissa D. Olfert

Loma Linda University Electronic Theses, Dissertations & Projects

A patient’s adherence to self-management therapies in diabetes strongly influences health outcomes, health care utilization, and ultimately health care costs. Engaging in regular exercise therapy reduces risk factors associated with type 2 diabetes. The purpose of this randomized prospective study was to determine if a client-centered approach (CCA) toward diabetes education, verses a traditional-directive approach (TDA), would improve exercise participation, perceived control, intention to exercise, and glycemic control in patients with type 2 diabetes.

Fifty-nine type 2 patients were randomized into two groups: CCA and TDA. Diabetes education in the CCA group provided empowerment toward acquiring knowledge, skills, and responsibility …