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Full-Text Articles in Physiology
Effects Of Hypobaric And Normobaric Hypoxia On Heart Rate And Blood Oxygen Saturation, Madison Brooks Coleman
Effects Of Hypobaric And Normobaric Hypoxia On Heart Rate And Blood Oxygen Saturation, Madison Brooks Coleman
UNO Student Research and Creative Activity Fair
There has been recent debate on the difference in physiological response between exposure to normobaric hypoxia (oxygen fraction altered) and hypobaric hypoxia (barometric pressure altered). Purpose: To determine the effects of normobaric normoxia (NN), hypobaric hypoxia (HH), and normobaric hypoxia (NH) on heart rate and arterial oxygen saturation (SaO2) after exercise. Methods: Fifteen recreationally active participants (eight males and seven females) completed three separate 1 h cycling bouts at 70% of their peak aerobic capacity. Following each trial, participants recovered in the supine position for 4 h in NN (975 m), HH (4420 m), or NH (4420 m). …
Oxygen Transport In Normobaric Versus Hypobaric Hypoxia, Christina N. Angeli
Oxygen Transport In Normobaric Versus Hypobaric Hypoxia, Christina N. Angeli
UNO Student Research and Creative Activity Fair
BACKGROUND: Various physiological changes occur in the human body when ascending to altitude. Exposure to hypoxia increases heart rate and decreases arterial oxygen saturation (SaO2), with both changes being expedited during exercise. Incremental exercise in ambient conditions decreases muscle oxygenation, specifically with increasing intensity. Previous research has examined heart rate and SaO2 in response to normobaric versus hypobaric hypoxia. However, there is lack of research examining muscle oxygenation in response to these conditions. Therefore, additional research investigating acute responses to normobaric and hypobaric hypoxia during exercise is warranted. PURPOSE: To examine acute responses in arterial and muscle …
Human Stress Protein Response To Exercise And The Environment, Rebecca Cuthbert
Human Stress Protein Response To Exercise And The Environment, Rebecca Cuthbert
UNO Student Research and Creative Activity Fair
Stress proteins are molecular chaperones that protect cells from the damaging effects that can be caused by exercise and environmental changes. Cold-inducible RNA binding protein (CIRP) and RNA binding motif protein 3 (RBM3) protect cells from mild hypothermia and hypoxia. They allow cells to rapidly respond to environmental stresses by regulating gene expression. Heat shock proteins 27, 70, and 90 protect skeletal tissue from exercise and heat stress. They accelerate cellular repair and prevent misfolding of proteins. These proteins, especially CIRP and RBM3, have been studied in cell cultures and animal models, but limited data exist in humans. Purpose: To …
Responses Of Appetite And Appetite Regulating Hormones To Acute Altitude Exposure, Morgan Busboom
Responses Of Appetite And Appetite Regulating Hormones To Acute Altitude Exposure, Morgan Busboom
UNO Student Research and Creative Activity Fair
PURPOSE: To determine the acute response of appetite and appetite regulating hormones after exposure to simulated altitude in resting conditions. METHODS: Seven male and six female recreationally active subjects (height 178±8.1cm, weight: 77.3±24.8kg, body fat: 18.4±5.7%) participated in two, three-hour trials in an environmental chamber with one trial simulating 5000 m altitude (hypoxic) and the other simulating 350 m altitude (control). Blood samples from the antecubital vein were collected prior to entering the environmental chamber and immediately following the three hours of seated rest. Blood samples were analyzed for serum leptin, adiponectin, and ghrelin concentrations via enzyme-linked immunosorbent …
Effects Of Normobaric And Hypobaric Hypoxia On Mitochondrial Related Gene Expression, Robert J. Shute
Effects Of Normobaric And Hypobaric Hypoxia On Mitochondrial Related Gene Expression, Robert J. Shute
UNO Student Research and Creative Activity Fair
Environmental stimuli such as temperature and hypoxia can influence cellular signaling in the skeletal muscle. Previously we have reported no changes in gene expression related to mitochondrial development with acute exposure to normobaric hypoxia. However, exposure to hypobaric hypoxia may elicit different physiological responses. Purpose: To determine the response of skeletal muscle mitochondrial related gene expression after 4 h of exposure to normobaric normoxia (NN), normobaric hypoxia (NH), and hypobaric hypoxia (HH) after exercise. Methods: Recreationally trained participants (8 male, 7 female) each completed three trials of 1-h cycling at 70% of Wmax. Following exercise, participants sat in …