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Full-Text Articles in Physiology
Extreme Exposure To Cold: A Method To Enhance Physical Wellness And Recovery, Mallory E. Duggan
Extreme Exposure To Cold: A Method To Enhance Physical Wellness And Recovery, Mallory E. Duggan
Student Publications
This paper reviews the current literature on Cryotherapy and its ability to enhance physical wellness and recovery. The paper details the proposed mechanisms of Cryotherapy as well as its various clinical applications regarding the treatment of numerous diseases and physical exercise recovery. The paper also details the possible limitations/detrimental effects of Cryotherapy usage.
Water Intoxication: Current Developments In Hyponatremia, Allison C. Mosmiller
Water Intoxication: Current Developments In Hyponatremia, Allison C. Mosmiller
Student Publications
This paper is a review of recent research on the subject of exercise-associated hyponatremia. Hyponatremia is notoriously difficult to diagnose and to treat due to its general symptoms and required specificity in diagnosis in order to assign appropriate treatment. If left untreated, Hyponatremia can result in the development of complications like cerebral edema, seizures, coma, and sometimes death. The pathogenesis of hyponatremia includes multiple proposed mechanisms, including overconsumption of hypotonic fluids, inappropriate release of antidiuretic hormone, inefficiency of fluid filtration by the kidneys, redirection of fluid into intestinal lumen, and activation of the renin-angiotensin-aldosterone system. Signs and symptoms of hyponatremia …
Amp-Activated Protein Kinase Controls Exercise Training - And Aicar-Induced Increases In Sirt3 And Mnsod, Josef Brandauer, Marianne A. Andersen, Holti Kellezi, Steve Risis, Christian Frozig, Sara G. Vienberg, Jonas T. Treebak
Amp-Activated Protein Kinase Controls Exercise Training - And Aicar-Induced Increases In Sirt3 And Mnsod, Josef Brandauer, Marianne A. Andersen, Holti Kellezi, Steve Risis, Christian Frozig, Sara G. Vienberg, Jonas T. Treebak
Health Sciences Faculty Publications
The mitochondrial protein deacetylase sirtuin (SIRT) 3 may mediate exercise training-induced increases in mitochondrial biogenesis and improvements in reactive oxygen species (ROS) handling. We determined the requirement of AMP-activated protein kinase (AMPK) for exercise training-induced increases in skeletal muscle abundance of SIRT3 and other mitochondrial proteins. Exercise training for 6.5 weeks increased SIRT3 (p < 0.01) and superoxide dismutase 2 (MnSOD; p < 0.05) protein abundance in quadriceps muscle of wild-type (WT; n = 13–15), but not AMPK α2 kinase dead (KD; n = 12–13) mice. We also observed a strong trend for increased MnSOD abundance in exercise-trained skeletal muscle of healthy humans (p = 0.051; n = 6). To further elucidate a role for …