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Full-Text Articles in Physiology
The Effects Of Ovariecotomy On Neuropeptide Y Neurotransmission In Skeletal Muscle Arterioles, Kirk Wendell Evanson
The Effects Of Ovariecotomy On Neuropeptide Y Neurotransmission In Skeletal Muscle Arterioles, Kirk Wendell Evanson
Graduate Theses and Dissertations
The purpose of this study was to determine the effects of chronic estrogen supplementation on NPY neurotransmission in gastrocnemius first-order arterioles (G1A) of adult female rats. Female rats (4 mo; n = 30) were ovariectomized (OVX) with a subset (n = 15) receiving an estrogen pellet (OVE; 17β-estradiol (4μg / day)). Following conclusion of the treatment phase (8 weeks), red G1A were excised, placed in a physiological saline solution (PSS) bath, and cannulated with micropipettes connected to albumin reservoirs. A sampling port was placed immediately below the vessel to assess NPY overflow. The contralateral red G1A was homogenized in PSS …