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Biology

Selected Works

2003

Articles 1 - 2 of 2

Full-Text Articles in Physiology

A Model For Shear Stress Sensing And Transmission In Vascular Endothelial Cells, Borbala Mazzag, John S. Tamaresis, Abdul Barakat May 2003

A Model For Shear Stress Sensing And Transmission In Vascular Endothelial Cells, Borbala Mazzag, John S. Tamaresis, Abdul Barakat

Borbala Mazzag

 Arterial endothelial cell (EC) responsiveness to flow is essential for normal vascular function and plays a role in the development of atherosclerosis. EC flow responses may involve sensing of the mechanical stimulus at the cell surface with subsequent transmission via cytoskeleton to intracellular transduction sites. We had previously modeled flow-induced deformation of EC-surface flow sensors represented as viscoelastic materials with standard linear solid behavior (Kelvin bodies). In the present article, we extend the analysis to arbitrary networks of viscoelastic structures connected in series and/or parallel. Application of the model to a system of two Kelvin bodies in parallel reveals that …

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Identification Of Asteroid Genera With Species Capable Of Larval Cloning, K. E. Knott, E. J. Balser, William Jaeckle Dec 2002

Identification Of Asteroid Genera With Species Capable Of Larval Cloning, K. E. Knott, E. J. Balser, William Jaeckle

William Jaeckle

Asexual reproduction in larvae, larval cloning, is a recently recognized component of the complex life histories of asteroids. We compare DNA sequences of mitochondrial tRNA genes (Ala, Leu, Asn, Pro and Gln) from larvae in the process of cloning collected in the field with sequences from adults of known species in order to identify asteroid taxa capable of cloning. Neighbor-joining analysis identified four distinct groups of larvae, each having no, or very little, sequence divergence (p distances ranging from 0.00000 to 0.02589); thus, we conclude that each larval group most likely represents a single species. These field-collected larvae cannot be …

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