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Full-Text Articles in Environmental Health
Evaluating The Cytotoxic Effects Of Cellulose Nanocrystals (Cncs) Using Autobioluminescent Yeast And Human Cells, Julianna Hughes Burchett
Evaluating The Cytotoxic Effects Of Cellulose Nanocrystals (Cncs) Using Autobioluminescent Yeast And Human Cells, Julianna Hughes Burchett
EURēCA: Exhibition of Undergraduate Research and Creative Achievement
Cellulose nanocrystals (CNCs) are widely used in different industries including pharmaceutical and cosmetic production due to their adept physical and biological properties. Because CNCs are becoming a more prevalent material and have a high potential of being redistributed in the environment, it is important to understand their toxic potentials in biological systems, including organisms of various trophic levels. This study evaluated the cytotoxic effects of CNCs in the lower eukaryotic organism Saccharomyces cerevisiae and human embryonic kidney (HEK293) cells using autobioluminescent yeast and human cell reporters, respectively. The S. cerevisiae and HEK293 reporter cells were engineered to express a synthetic …