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Impact Of Cefazolin Co-Administration With Vancomycin To Reduce Development Of Vancomycin Intermediate Staphylococcus Aureus, Nivedita Birbahadur Singh
Impact Of Cefazolin Co-Administration With Vancomycin To Reduce Development Of Vancomycin Intermediate Staphylococcus Aureus, Nivedita Birbahadur Singh
Wayne State University Theses
IMPACT OF CEFAZOLIN CO-ADMINISTRATION WITH VANCOMYCIN TO REDUCE DEVELOPMENT OF VANCOMYCIN INTERMEDIATE STAPHYLOCOCCUS AUREUS
by
NIVEDITA B SINGH
August 2106
Advisor: Dr. Michael J. Rybak
Major: Pharmaceutical sciences
Degree: Masters of Science
Objective: Development of resistance in S. aureus has been a big concern in the treatment of infections caused by the organism. The line of therapy used today has a disadvantage of slowly developing cross-resistance for antibiotics such as DAP secondary to prior VAN exposure. Therefore, alternative therapy is needed to prevent the emergence of VAN resistance and cross-resistance to other antibiotics. The primary aim of this experiment is …