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Valery Forbes Publications

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Full-Text Articles in Pharmacology, Toxicology and Environmental Health

Does Bisphenol A Induce Superfeminization In Marisa Cornuarietis? Part I: Intra- And Inter-Laboratory Variability In Test Endpoints, Valery E. Forbes, Henriette Selck, Annemette Palmqvist, John Aufderheide, Ryan Warbritton, Nadine Pounds, Roy Thompson, Norbert Caspers Jan 2007

Does Bisphenol A Induce Superfeminization In Marisa Cornuarietis? Part I: Intra- And Inter-Laboratory Variability In Test Endpoints, Valery E. Forbes, Henriette Selck, Annemette Palmqvist, John Aufderheide, Ryan Warbritton, Nadine Pounds, Roy Thompson, Norbert Caspers

Valery Forbes Publications

It has been claimed that bisphenol A (BPA) induces superfeminization in the freshwater gastropod, Marisa cornuarietis. To explore the reproducibility of prior work, here we present results from a three-laboratory study, the objectives of which were to determine the mean and variability in test endpoints (i.e., adult fecundity, egg hatchability, and juvenile growth) under baseline conditions and to identify the sources of variability. A major source of variability for all of the measured endpoints was due to differences within and among individuals. With few exceptions, variability among laboratories and among replicate tanks within laboratories contributed little to the observed variability …


Does Bisphenol A Induce Superfeminization In Marisa Cornuarietis? Part Ii: Toxicity Test Results And Requirements For Statistical Power Analyses, Valery E. Forbes, John Aufderheide, Ryan Warbritton, Nelly Van Der Hoeven, Norbert Caspers Jan 2007

Does Bisphenol A Induce Superfeminization In Marisa Cornuarietis? Part Ii: Toxicity Test Results And Requirements For Statistical Power Analyses, Valery E. Forbes, John Aufderheide, Ryan Warbritton, Nelly Van Der Hoeven, Norbert Caspers

Valery Forbes Publications

This study presents results of the effects of bisphenol A (BPA) on adult egg production, egg hatchability, egg development rates and juvenile growth rates in the freshwater gastropod, Marisa cornuarietis. We observed no adult mortality, substantial inter-snail variability in reproductive output, and no effects of BPA on reproduction during 12 weeks of exposure to 0, 0.1, 1.0, 16, 160 or 640 μg/L BPA. We observed no effects of BPA on egg hatchability or timing of egg hatching. Juveniles showed good growth in the control and all treatments, and there were no significant effects of BPA on this endpoint. Our …


Effects Of Husbandry Parameters On The Life-History Traits Of The Apple Snail, Marisa Cornuarietis: Effects Of Temperature, Photoperiod, And Population Density, John Aufderheide, Ryan Warbritton, Nadine Pounds, Sharon File-Emperador, Charles Staples, Norbert Caspers, Valery E. Forbes Jan 2006

Effects Of Husbandry Parameters On The Life-History Traits Of The Apple Snail, Marisa Cornuarietis: Effects Of Temperature, Photoperiod, And Population Density, John Aufderheide, Ryan Warbritton, Nadine Pounds, Sharon File-Emperador, Charles Staples, Norbert Caspers, Valery E. Forbes

Valery Forbes Publications

These experiments are part of a larger study designed to investigate the influence of husbandry parameters on the life history of the apple snail, Marisa cornuarietis. The overall objective of the program is to identify suitable husbandry conditions for maintaining multigeneration populations of this species in the laboratory for use in ecotoxicological testing. In this article, we focus on the effects of photoperiod, temperature, and population density on adult fecundity and juvenile growth. Increasing photoperiod from 12 to 16 h of light per day had no effect on adult fecundity or egg hatching and relatively minor effects on juvenile growth …