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Role Of Bax, Ibpa, Ibpb And Csph Genes In Protecting Cft073 (Uropathogenic Escherichia Coli) Against Salt And Urea Stress, Pavani Beesetty

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Uropathogenic Escherichia coli (UPEC) are the primary cause of 80 to 90% of uncomplicated urinary tract infections. After entering the urinary tract, uropathogenic E.coli has to tolerate high levels of salt and urea in urine to cause a successful infection. The osmotic stress imposed by urea is different from that by NaCl, as urea can freely move across the cell membrane and is a protein denaturant. Hence, microarray experiments were performed to observe the differential expression of genes in CFT073 (UPEC) due to the presence of 0.3 M NaCl and 0.6 M urea in K medium individually. Based on the …