Pharmacology, Toxicology and Environmental Health Commons^™

The Role Of The State, Multinational Oil Companies, International Law & The International Community: Intersection Of Human Rights & Environmental Degradation Climate Change In The 21st Century Caused By Traditional Extractive Practices, The Amazon Rainforest, Indigenous People And Universal Jurisdiction To Resolve The Accountability Issue, Marcela Cabrera Luna

Master's Theses

Local, national and international conventions that protect indigenous sovereignty and their territories, where many of the resources are extracted from by multinational corporations (MNCs) particularly oil, the number one commodity of the world and cause of climate change, continue to be jeopardized because of the lack of a clear international legal framework that can protect them and potentially hold multinationals accountable for their actions. These practices are causing not only environmental issues to the indigenous and surrounding communities, but climate change is in fact, the real human rights issue of the 21^st century and it affects everyone. By using …

High Prevalence And Genetic Heterogeneity Of Rodent-Borne Bartonella Species On Heixiazi Island, China, Dong-Mei Li, Yong Hou, Xiu-Ping Song, Ying-Qun Fu, Gui-Chang Li, Ming Li, Marina E. Eremeeva, Hai-Xia Wu, Bo Pang, Yu-Juan Yue, Ying Huang, Liang Lu, Jun Wang, Qi-Yong Liu

Environmental Health Sciences Faculty Publications

We performed genetic analysis of Bartonella isolates from rodent populations from Heixiazi Island in northeast China. Animals were captured at four sites representing grassland and brushwood habitats in 2011 and examined for the prevalence and genetic diversity of Bartonella species, their relationship to their hosts, and geographic distribution. A high prevalence (57.7%) and a high diversity (14 unique genotypes which belonged to 8 clades) of Bartonella spp. were detected from 71 rodents comprising 5 species and 4 genera from 3 rodent families. Forty-one Bartonella isolates were recovered and identified, including B. taylorii, B. japonica, B. coopersplainsensis, B. grahamii, B. washoensis …

Iodine-131: Measurement And Application Of A Novel Tracer In Lake Michigan, Michael Patrick Montenero

Theses and Dissertations

Iodine-131 is a short-lived (half-life=8.0233 days), gamma emitting, radiopharmaceutical that, when excreted by patients, enters aquatic systems via sewage effluent discharged from water reclamation facilities (WRFs). Here, I report on 131I activities in the nearshore of southwest Lake Michigan in the vicinity of Milwaukee, Wisconsin. This is the first report on 131I activity in any of the Great Lakes of North America.

The flux of 131I from Milwaukee’s two WRFs was monitored from July 2013 to December 2014. Mean discharge of 131I from the Jones Island WRF was (0.664 ± 0.012)×108 Bq d-1 (mean effluent 131I activity: ~0.25 Bq L-1; …

The Identification And Quantification Of Sewage Contamination In The Milwaukee Estuary, Hayley Templar

Theses and Dissertations

Sewage contamination from failing infrastructure and sewer overflows is a major environmental and human health concern in waterways, especially in urban communities bordering the Great Lakes such as Milwaukee, Wisconsin. Culture-based fecal indicator bacteria, such as Escherichia coli, enterococci, and fecal coliforms are traditionally used to indicate the presence of a human health risk due to fecal contamination. These indicators, however, fail to distinguish between sources of fecal contamination (human vs. non-human). Two human-specific fecal indicators, human Bacteroides and human Lachnospiraceae, were used to identify and quantify sewage contamination in the Milwaukee estuary, which discharges to Lake Michigan, as well …

Comparative Aquatic Toxicity Of A Commercial Naphthenic Acid And Processes For Mitigating Risks, Ciera Kinley

All Theses

Comparative toxicity data can inform predictions of relative risk, and can be used to implement strategies for altering exposures to mitigate risk. Naphthenic acids (NAs) are a complex group of carboxylic acids that naturally occur in petroleum sources and energy-derived process waters (e.g. refinery effluents and oil sands process affected waters). These compounds are relatively persistent in water and can be a source of toxicity to aquatic organisms. In the first experiment of this thesis, responses of sentinel aquatic organisms to 7-d exposures of commercial (Fluka) NAs were measured (in terms of acute toxicity) to discern relative sensitivities. In terms …

Macrobenthic Communities In The Northern Gulf Of Mexico Hypoxic Zone: Testing The Pearson-Rosenberg Model, Shivakumar Shivarudrappa

Dissertations

The Pearson and Rosenberg (P-R) conceptual model of macrobenthic succession was used to assess the impact of hypoxia (dissolved oxygen [DO] ≤ 2 mg/L) on the macrobenthic community on the continental shelf of northern Gulf of Mexico for the first time. The model uses a stress-response relationship between environmental parameters and the macrobenthic community to determine the ecological condition of the benthic habitat. The ecological significance of dissolved oxygen in a benthic habitat is well understood. In addition, the annual recurrence of bottom-water hypoxia on the Louisiana/Texas shelf during summer months is well documented.

The P-R model illustrates the decreasing …

Re-Emergence Of The Harmful Algal Bloom Species Alexandrium Monilatum In The Chesapeake Bay: Assessing Bloom Dynamics And Potential Health Impacts, Sarah K.D. Pease, Kimberly S. Reece, Wolfgang K. Vogelbein

Presentations

Effective management of harmful algal blooms (HABs) within a region requires an understanding of species-specific HAB spatial and temporal distributions, bloom dynamics, as well as potential health impacts. In 2007, the southern Chesapeake Bay witnessed its first blooms of the HAB species Alexandrium monilatum. Since then, A. monilatum has bloomed in the region almost annually. A. monilatum produces the toxin ‘goniodomin A’ and is suspected in local mass mortalities of oyster larvae (Crassostrea virginica) grown for aquaculture and restoration projects. Representatives from Virginia’s multimillion dollar oyster aquaculture industry recently expressed great concern over A. monilatum impacts to their businesses; field …

Efficacy Of Sediment Remediation Efforts On Pah Contaminant Flux Via Porewater Advection At The Sediment-Surface Water Interface, Julie L. Krask, Michael A. Unger, George G. Vadas, Michele A. Cochran, Aaron J. Beck

Presentations

Groundwater advection at the sediment-surface water interface is an important biogeochemical mechanism controlling the transport and bioavailability of contaminants in estuaries. At sites along the Elizabeth River (VA, USA) where the subterranean environment is heavily contaminated with polycyclic aromatic hydrocarbon (PAH)-rich dense non-aqueous phase liquid (DNAPL), consideration of groundwater-surface water dynamics and associated chemical exchange is critical for effective remediation. Preliminary data suggest that porewater advection in permeable sediments at this location is controlled by a host of physical forcing mechanisms that correspond with total flow estimates of up to 15,000 centimeters/year. Here, the efficacy of sediment remediation strategies, including …

Using Choice Experiment Valuation Methods To Measure Public Preference For A New National Park In Maine, Alexander G. Wilsterman

Journal of Environmental and Resource Economics at Colby

With global population increasing faster than ever, the need to protect land from development is at an all-time high. This paper seeks the measure the public preference for a new national park located in northern Maine. A national park will both protect the land and inject a much-needed economic stimulus to the surrounding communities. The study uses the choice experiment valuation method to quantify its results. Through this revealed preference we can quantify which characteristics are most important to the public so that these characteristics may be considered if the project is ever approved.

Golf Courses In Maine: Land Type Valuation Versus A Hedonic Pricing Analysis, Gregory Ladd, Jason Buco

Journal of Environmental and Resource Economics at Colby

Many studies have been conducted analyzing the economic impact of golf courses on the local communities. These studies examine economic impacts of tournaments, endorsements, and vacation expenses of the major golf courses in the United States. However, there is little research conducted on the environmental impact of Golf courses, specifically in Maine. This paper performs a hedonic pricing analysis using housing prices in proximity to golf courses and compares it to the valuation of various land types in Maine. Housing prices were collected in the towns of Auburn, and North Yarmouth both near and distant from the local golf course. …

Cost Benefit Analysis Of Café Standards Compared To The Alternative Fuel/Carbon Tax, Brian Levinson

Journal of Environmental and Resource Economics at Colby

The Cafe Standards were introduced in 1975 following the Oil Embargo. The goals of this program were simple. To reduce co2 emissions in vehicles by increasing a mandatory average mpg level for car manufacturers in the United States. Recently, in 2012, the Obama Administration set new Cafe Standard requirements for car manufacturers. By 2025, all new cars on the road in the United States must average 54.5 miles per gallon, which would double the current 27 mpg average in place right now. While the intentions of this policy are to reduce co2 emissions while at the same time increasing savings …

The Economics Of The Audubon Society's Sanctuary Program For Golf Courses, Dan Hyszczak

Journal of Environmental and Resource Economics at Colby

Millions of people play golf every year, and in 2011 Golf Courses gained $22 billion dollars in revenue. This statistic combined with golf’s inherent place in the natural environment lead to questions of value and development for golf course owners. In 1991, The Audubon Society created their Cooperative Sanctuary Program for Golf Courses (ACSP) to promote environmentally sustainable practices for golf courses and to recognize the courses that are the most environmentally in both the United States and around the world.

This paper builds off of prior research that connects golf course beauty with revenue by examining the effects of …

Preferences For Coral Reef And Fishery Management In Okinawa, Japan, Nils Carlson

Journal of Environmental and Resource Economics at Colby

This study is an example of how a nonmarket valuation method – a choice experiment – can be used to influence and guide ecosystem conservation efforts. Using a choice experiment survey, this study estimates the willingness to pay (WTP) for certain hypothetical attributes of a restored and conserved coral reef in Okinawa, Japan. I find that an increase in the amount of fish available to catch in ten years as well as an increase in the extent and health of the coral reefs and the number of marine biodiversity found in the Okinawan waters after ten-years, both positively affect respondent’s …

An Exploratory Statistical Analysis Of The External And Internal Effects Of Art Museums In The United States, John Eder

Journal of Environmental and Resource Economics at Colby

An Exploratory Statistical Analysis of the External and Internal Effects of Art Museums in the United States

The Effects Of Land Conservation On Productivity, Robert Mccormick, Carolyn Fuwa

Journal of Environmental and Resource Economics at Colby

In this research the relationship between productivity of land conservation is analyzed using panel data of the GDP and acres conserved of all 50 U.S. states from 1998-2005. Two main theories of the conservation productivity relationship exist. The first maintains that conservation impedes productivity because it does not allow land cultivation. Conversely, the second theory maintains that land conservation has a positive effect on GDP due to the recreation and tourism it creates. Through the use of fixed effects and random effects regressions, the amount of land conserved per state is not a significant predictor of state GDP The GDP …

A Survey On Climate Change: How Beliefs Shape Responsibility, Connor P. Clancy, Sarah Beth Solomon

Journal of Environmental and Resource Economics at Colby

This paper examines the lack of awareness and feelings of personal responsibility for climate change. Previous literature suggests that while part of the United States population may be aware of climate change, they do not feel personally responsible for causing it despite feeling climate change’s effects just like everyone else. Furthermore, studies suggest that individuals also do not believe climate change will affect them now, but rather it is an issue for future generations. Using a survey, we examine which demographics and personal factors are most important in eliciting awareness for climate change, and furthermore, personal responsibility for its effects. …

Invited Introduction To Jerec, Noelwah Netusil

Journal of Environmental and Resource Economics at Colby

No abstract provided.

Welcome By The Editor, Sahan T. M. Dissanayake

Journal of Environmental and Resource Economics at Colby

No abstract provided.

Physicochemical And Toxicological Assessment Of Antimicrobial Ε-Polylysine-Pectin Complexes, Cynthia L. Lopez Pena

Doctoral Dissertations

ε-Polylysine is an appealing FDA-approved, all natural antimicrobial biopolymer effective against a wide range of microorganisms. Its implementation is greatly limited by its strong cationic charge, which has been linked to instability in food systems, perceived astringency and bitterness, and the ability to inhibit lipid digestion. Previous studies have shown that controlled complexation of ε-polylysine with anionic pectin is able to prevent instability and astringency in simplified model food systems, while maintaining the antimicrobial character of polylysine. Isothermal titration calorimetry, micro-electrophoresis, microscopy, and turbidity analyses of the stability of electrostatic pectin-polylysine complexes in the presence of strongly anionic κ-carrageenan, and …

Histopathological Studies And Heavy Metals Accumulation In Water, Sediment And Chrysichthys Nigrodigitatus At The Agility Iarea Of The Ogun River, S. O. Ayoola, G. Ahamefule, H. O. Omogoriola

21st International Conference on Environmental Indicators (ICEI 2015)

No abstract provided.

Sustaining The Saco Estuary: Final Report 2015, Christine B. Feurt Ph D, Pamela A. Morgan, Mark D. O. Adams, Anna L. Bass, Carrie J. Byron, Michael C. Daley, Michael O. Esty, Noah G. Perlut, Kayla Smith, Tyler Spillane, Michelle M. Steen-Adams, James Sulikowski, Stephan I. Zeeman, Jacob Aman, Michele Dionne, Jeremy Miller, Kristin Wilson

Environmental Studies Faculty Publications

This study focuses on the Saco estuary, the tidal portion of the Saco River, which drains the largest watershed in southern Maine. With headwaters in the White Mountains of New Hampshire, the watershed encompasses more than 4,400 km², and provides clean healthy drinking water to over 100,000 people living and working in communities in southern Maine.

When the study began in 2009, very little was known about the ecology of the Saco estuary. Researchers at the University of New England and the Wells National Estuarine Research Reserve employed the process of collaborative learning to bring together people who …

Mangiferin As A Biomarker For Mango Anthracnose Resistance, Herma Pierre

FIU Electronic Theses and Dissertations

Mangos (Mangifera indica L.) are tropical/subtropical fruits belonging to the plant family Anacardiaceae. Anthracnose is the most deleterious disease of mango both in the field and during postharvest handling. It is most commonly caused by the Colletotrichum gloeosporioides complex. Mangiferin, a xanthanoid compound found in at least twelve plant families worldwide (Luo et al., 2012), is present in large amounts of the leaves and edible mangos. Even though this compound plays a pivotal role in the plant’s defense against biotic and abiotic stressors, no correlations been made between the compound and mango anthracnose resistance.

Mangos were collected, grouped …

Modification Of Traffic-Related Respiratory Response By Asthma Control In A Population Of Car Commuters, Maria C. Mirabelli, Rachel Golan, Roby Greenwald, Amit U. Raysoni, Fernando Holguin, Priya Kewada, Andrea Winquist, W Dana Flanders, Jeremy A. Sarnat

School of Earth, Environmental, and Marine Sciences Faculty Publications and Presentations

Background: Effects of traffic-related exposures on respiratory health are well documented, but little information is available about whether asthma control influences individual susceptibility. We analyzed data from the Atlanta Commuter Exposure study to evaluate modification of associations between rush-hour commuting, in- vehicle air pollution, and selected respiratory health outcomes by asthma control status.

Methods: Between 2009 and 2011, 39 adults participated in Atlanta Commuter Exposure, and each conducted two scripted rush-hour highway commutes. In-vehicle particulate components were measured during all commutes. Among adults with asthma, we evaluated asthma control by questionnaire and spirometry. Exhaled nitric oxide, forced expiratory volume in …

Kinetic Modeling Of Catalytic Aerogels, Yi Cao

Honors Theses

As pollution becomes an increasing concern globally, strict regulations have been set on vehicle pollutant emissions. The three-way catalytic converter is capable of converting toxic emissions such as carbon monoxide, unburned hydrocarbons and nitrogen oxides to less hazardous waste such as carbon dioxide, water, and nitrogen. Current catalysts employ platinum group metals, which are expensive and environmentally damaging to mine. Catalytically-active aerogels such as Co-Al, Cu-Al and V-Al aerogels have shown promise as alternatives to these metals. The work presented here adapts and extends a global kinetic model which predicts the conversion of hydrocarbons and carbon monoxide on platinum catalyst …

Sem-Edx Analysis Of Aerosol Samples, Xuanhan Zhao

Honors Theses

One of the important environmental issues in upstate New York is the acid rain problem in the Adirondack Mountains, which is associated with atmospheric aerosols. As a part of a systematic study to understand the transport, transformation, and effects of airborne pollutants in the Adirondack Mountains, we are performing an analysis of atmospheric aerosols collected at Piseco Lake. In previous work, we used proton induced X-ray emission (PIXE) [1] spectrometry to measure the concentrations of elements in aerosol samples as a function of the size of the particulate matter. The results of the PIXE analysis indicate significant concentrations of sulfur …

Examining The Toxicity, Exposure, And Regulatory Approach To Potential Human Health Risks Of The Algal Toxin Domoic Acid, Thomas H. Angus

Graduate Doctoral Dissertations

Domoic acid is a neurotoxin produced by the marine diatom genus Pseudo-nitzschia and causes cell death primarily in the area of the brain responsible for long-term memory. The resulting severe illness has been termed amnesic shellfish poisoning. Domoic acid accumulates in shellfish and planktivorous fish that consume Pseudo-nitzschia, resulting in exposure to humans through consumption of planktivorous seafood. A regulatory standard in seafood was developed shortly after its discovery in 1987 to protect against acute effects. This regulatory standard has not been revised despite significant recent data in the scientific literature.

This dissertation is divided into four sections: (1) …

Surface And Subsurface Application Of Chemical Dispersants And Associated Ecosystem Impacts, Adam V. Radpour

Master's Projects and Capstones

Chemical dispersants are applied to spilled oil in marine environments when other, less controversial, methods are not adequate for the incident. They are considered to be a response method as opposed to a direct cleanup method, with the intended goals of reducing risk of exposure to sensitive shorelines, reducing environmental injury to surface-dwelling sea birds and marine mammals, and facilitating the biodegradation of spilled oil into the water column.

For this research, both surface and subsurface application of dispersants were evaluated in terms of oil characteristics and volume, and oceanic and atmospheric conditions. More data exists to support the effectiveness …

Impacts Of Consumer Horticulture On Stormwater And Nutrient Management: Investigating Public Perception, Knowledge, And Practices In The Shenandoah River Watershed, Christopher P. Parker

Masters Theses, 2010-2019

The South Fork Shenandoah River is a tributary to the Chesapeake Bay that is a significant contributor to nitrogen and phosphorus that enter the Bay and leads to increased eutrophication. These nutrients also cause problems in the South Fork Shenandoah River. The United States Environmental Protection agency has implemented strict regulation to reduce nutrients entering the Bay by developing the Chesapeake Bay TMDL. While the TMDL has strict regulation on wastewater treatment, agriculture, and industry, there are still sources of nutrients entering the Bay through unregulated sources. Urban/suburban runoff is one of these sources, particularly runoff from home owner’s lawns. …

Acute Toxicity Of Β-N-Methylamino-L-Alanine (Bmaa) To Fathead Minnow (Pimephales Promelas) And Zebrafish (Danio Rerio), Jiayi Wang

School of Natural Resources: Dissertations, Theses, and Student Research

β-N-methylamino-L-alanine (BMAA) is a neurotoxic amino acid produced by most species of cyanobacteria. Exposure to BMAA has been hypothesized as a cause of ALS and possibly Parkinson’s and Alzheimer’s diseases for several decades. Both in vitro and in vivo experiments revealed that exposure to elevated concentrations of BMAA can damage motor neurons and cause motor dysfunctions. However, the exact mechanism of BMAA-induced neurotoxicity has not been well understood.

Based on the available literature and in spite of its water-soluble and non-protein nature, BMAA appears to be able to bioaccumulate in organisms. The ubiquity of cyanobacteria and the potential for bioaccumulation …

Female Reproductive Impacts Of Dietary Methylmercury In Yellow Perch (Perca Flavescens) And Zebrafish (Danio Rerio), Abigail Rachael Debofsky

Theses and Dissertations

This study sought to evaluate the effects of dietary MeHg exposure on female teleost reproduction and phenotypically-anchor gene dysregulation in adult yellow perch (Perca flavescens) and zebrafish (Danio rerio) in order to establish relevant biomarkers relating exposure and subsequent reproductive effects. Yellow perch were used in the study for their socioeconomic importance within the Great Lakes basin, and their significance to the food web. Utilization of zebrafish allowed for a detailed analysis of the molecular effects of MeHg and established its relevance as a model for other fish species. MeHg exposures at environmentally relevant levels were done in zebrafish for …