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Articles 151 - 180 of 293
Full-Text Articles in Other Nutrition
Voices For Food: Methodologies For Implementing A Multi-State Community-Based Intervention In Rural, High Poverty Communities, Suzanne Stluka, Lindsay Moore, Heather A. Eicher-Miller, Lisa Franzen-Castle, Becky Henne, Donna Mehrle, Daniel Remley, Lacey Mccormack
Voices For Food: Methodologies For Implementing A Multi-State Community-Based Intervention In Rural, High Poverty Communities, Suzanne Stluka, Lindsay Moore, Heather A. Eicher-Miller, Lisa Franzen-Castle, Becky Henne, Donna Mehrle, Daniel Remley, Lacey Mccormack
Department of Nutrition and Health Sciences: Faculty Publications
Background: Rural communities experience unique barriers to food access when compared to urban areas and food security is a public health issue in rural, high poverty communities. A multi-leveled socio-ecological intervention to develop food policy councils (FPCs), and improve food security in rural communities was created. Methods to carry out such an intervention were developed and are described.
Methods: A longitudinal, matched treatment and comparison study was conducted in 24 rural, high poverty counties in South Dakota, Indiana, Missouri, Michigan, Nebraska and Ohio. Counties were assigned to a treatment (n = 12) or comparison (n = 12) group. Intervention activities …
Effects Of Intensity On Muscle-Specific Voluntary Electromechanical Delay And Relaxation Electromechanical Delay, Cory M. Smith, Terry J. Housh, Ethan C. Hill, Josh L. Keller, Glen O. Johnson, Richard J. Schmidt
Effects Of Intensity On Muscle-Specific Voluntary Electromechanical Delay And Relaxation Electromechanical Delay, Cory M. Smith, Terry J. Housh, Ethan C. Hill, Josh L. Keller, Glen O. Johnson, Richard J. Schmidt
Department of Nutrition and Health Sciences: Faculty Publications
The purposes of this study were to examine: 1) the potential muscle-specific differences in voluntary electromechanical delay (EMD) and relaxation electromechanical delay (R-EMD), and 2) the effects of intensity on EMD and R-EMD during step incremental isometric muscle actions from 10 to 100% maximal voluntary isometric contraction (MVIC). EMD and R-EMD measures were calculated from the simultaneous assessments of electromyography, mechanomyography, and force production from the vastus lateralis (VL), vastus medialis (VM), and rectus femoris (RF) during step isometric muscle actions. There were no differences between the VL, VM, and RF for the voluntary EMDE-M (onsets of the electromyographic …
Need (More Than) Two To Tango: Multiple Tools To Adapt To Changes In Oxygen Availability, Deborah Fratantonio, Francesco Cimino, Antonio Speciale, Fabio Virgili
Need (More Than) Two To Tango: Multiple Tools To Adapt To Changes In Oxygen Availability, Deborah Fratantonio, Francesco Cimino, Antonio Speciale, Fabio Virgili
Department of Nutrition and Health Sciences: Faculty Publications
Oxygen is a fundamental element for the life of a large number of living organisms allowing an efficient energetic utilization of substrates. Organisms relying on oxygen evolved complex structures for oxygen delivery and biochemical machineries dealing with its safe utilization and the ability to overcome the potentially harmful consequences of changes in oxygen availability. On fact, cells composing complex Eukaryotic organisms are set to live within an optimum narrow range of oxygen, quite specific for each cell type. Minute modifications of oxygen availability, either positive or negative, induce the expression of specific genes, the major actors of this responses being …
Development And Validation Of A Simple Convenience Store Shelf Audit, Tanya M. Horacek, Elif Dede Yildirim, Erin Kelly, Adrienne A. White, Karla P. Shelnutt, Kristin Riggsbee, Melissa D. Olfert, Jesse Stabile Morrell, Anne E. Matthews, Terezie T. Mosby, Tandalayo Kidd, Kendra Kattelmann, Geoffrey Greene, Lisa Franzen-Castle, Sarah E. Colby, Carol Byrd-Bredbenner, Onikia Brown
Development And Validation Of A Simple Convenience Store Shelf Audit, Tanya M. Horacek, Elif Dede Yildirim, Erin Kelly, Adrienne A. White, Karla P. Shelnutt, Kristin Riggsbee, Melissa D. Olfert, Jesse Stabile Morrell, Anne E. Matthews, Terezie T. Mosby, Tandalayo Kidd, Kendra Kattelmann, Geoffrey Greene, Lisa Franzen-Castle, Sarah E. Colby, Carol Byrd-Bredbenner, Onikia Brown
Department of Nutrition and Health Sciences: Faculty Publications
Background This paper describes the development, reliability, and convergent validity of a practical tool—the Convenience Store Supportive Healthy Environment for Life-Promoting Food (SHELF) Audit. Methods Audit items included: a variety of fresh, processed, and frozen fruits and vegetables; low-fat dairy products; healthy staples and frozen meals; healthy food incentive programs; items sold in check-out areas; portion/cup sizes; and pricing. Each audit item was scored using a five-point semantic-differential scale (1 = provides little or no support for healthful foods to 5 = provides high support for healthful foods). Convergent validity was examined by comparing the SHELF audit to Ghirardelli et …
More Than Fast Food: Development Of A Story Map To Compare Adolescent Perceptions And Observations Of Their Food Environments And Related Food Behaviors, Kristin A. Riggsbee, Jonathon Riggsbee, Melissa J. Vilaro, Lauren Moret, Marsha Spence, Elizabeth Anderson Steeves, Wenjun Zhou, Melissa D. Olfert, Lisa Franzen-Castle, Tanya Horacek, Elizabeth Hall, Sarah E. Colby
More Than Fast Food: Development Of A Story Map To Compare Adolescent Perceptions And Observations Of Their Food Environments And Related Food Behaviors, Kristin A. Riggsbee, Jonathon Riggsbee, Melissa J. Vilaro, Lauren Moret, Marsha Spence, Elizabeth Anderson Steeves, Wenjun Zhou, Melissa D. Olfert, Lisa Franzen-Castle, Tanya Horacek, Elizabeth Hall, Sarah E. Colby
Department of Nutrition and Health Sciences: Faculty Publications
The purpose of this convergent, multiphase, mixed methods study was to better understand the perceptions of adolescents’ food environments and related food behaviors using grounded visualization and story mapping. Adolescents from one high school (13–16 years) in the southeastern United States were evaluated via data from health behavior surveys (n = 75), school environment maps, focus groups (n = 5 groups), and Photovoice (n = 6) from October 2016 to April 2017. Data from each phase were integrated using grounded visualization and new themes were identified (n = 7). A story map using ArcGIS Online was developed from data integration, …
St. John’S Wort Regulates Proliferation And Apoptosis In Mcf-7 Human Breast Cancer Cells By Inhibiting Ampk/Mtor And Activating The Mitochondrial Pathway, Mi-Kyoung You, Hwa-Jin Kim, Ji Hyun Kook, Hyeon-A Kim
St. John’S Wort Regulates Proliferation And Apoptosis In Mcf-7 Human Breast Cancer Cells By Inhibiting Ampk/Mtor And Activating The Mitochondrial Pathway, Mi-Kyoung You, Hwa-Jin Kim, Ji Hyun Kook, Hyeon-A Kim
Department of Nutrition and Health Sciences: Faculty Publications
St. John’s Wort (SJW) has been used as an estrogen agonist in the systems affected by menopause. Also, hypericin, a bioactive compound of SJW, has been used as a photosensitizer in photodynamic therapy. In the present study, we investigate the anti-proliferative and pro-apoptotic effects of SJWto demonstrate the chemo-preventive effect in human breast cancer cells. MCF-7 cellswere culturedwith DMSO or various concentrations of SJWethanol extract (SJWE). Cell viability, proliferation, apoptosis, the expression of proteins involved in cell growth and apoptosis, and caspase-3/7 activity were examined. SJWE dose-dependently suppressed cell growth and induced apoptosis ofMCF-7 cells. Mechanistically, SJWE enhanced the phosphorylation …
Health Disparities Score Composite Of Youth And Parent Dyads From An Obesity Prevention Intervention: Icook 4-H, Melissa D. Olfert, Makenzie L. Barr, Rebecca L. Hagedorn, Lisa Franzen-Castle, Sarah E. Colby, Kendra K. Kattelmann, Adrienne A. White
Health Disparities Score Composite Of Youth And Parent Dyads From An Obesity Prevention Intervention: Icook 4-H, Melissa D. Olfert, Makenzie L. Barr, Rebecca L. Hagedorn, Lisa Franzen-Castle, Sarah E. Colby, Kendra K. Kattelmann, Adrienne A. White
Department of Nutrition and Health Sciences: Faculty Publications
iCook 4-H is a lifestyle intervention to improve diet, physical activity and mealtime behavior. Control and treatment dyads (adult primary meal preparer and a 9–10-year-old youth) completed surveys at baseline and 4, 12, and 24 months. A Health Disparity (HD) score composite was developed utilizing a series of 12 questions (maximum score = 12 with a higher score indicating a more severe health disparity). Questions came from the USDA short form U.S. Household Food Security Survey (5), participation in food assistance programs (1), food behavior (2), level of adult education completed (1), marital status (1), and race (1 adult and …
Sex- And Mode-Specific Responses To Eccentric Muscle Fatigue, Ethan C. Hill, Terry J. Housh, Cory M. Smith, Josh L. Keller, Richard J. Schmidt, Glen O. Johnson
Sex- And Mode-Specific Responses To Eccentric Muscle Fatigue, Ethan C. Hill, Terry J. Housh, Cory M. Smith, Josh L. Keller, Richard J. Schmidt, Glen O. Johnson
Department of Nutrition and Health Sciences: Faculty Publications
The primary purpose of the present investigation was to examine sex-related differences as a result of fatiguing eccentric muscle actions on torque, muscle blood flow, electromyography, and mechanomyography. Eighteen men and 18 women performed peak torque trials prior to (pretest), immediately after (posttest), and 5-min after (recovery) completing 50 submaximal (60 % of eccentric peak torque), eccentric, isokinetic (180 ° · s − 1) muscle actions of the elbow flexors. Electromyographic and mechanomyographic responses were simultaneously recorded from the biceps brachii muscle, and muscle blood flow was measured at pretest, posttest and recovery. There were sex- and mode-specific responses for …
Red Pepper Seed Water Extract Inhibits Preadipocyte Differentiation And Induces Mature Adipocyte Apoptosis In 3t3-L1 Cells, Hwa-Jin Kim, Mi-Kyoung You, Young-Hyun Lee, Hyun-Jung Kim, Deepak Adhikari, Hyeon-A Kim
Red Pepper Seed Water Extract Inhibits Preadipocyte Differentiation And Induces Mature Adipocyte Apoptosis In 3t3-L1 Cells, Hwa-Jin Kim, Mi-Kyoung You, Young-Hyun Lee, Hyun-Jung Kim, Deepak Adhikari, Hyeon-A Kim
Department of Nutrition and Health Sciences: Faculty Publications
BACKGROUND/OBJECTIVES: Reducing the number of adipocytes by inducing apoptosis of mature adipocytes as well as suppressing differentiation of preadipocytes plays an important role in preventing obesity. This study examines the anti-adipogenic and pro-apoptotic effect of red pepper seed water extract (RPS) prepared at 4°C (RPS4) in 3T3-L1 cells.
MATERIALS/METHODS: Effect of RPS4 or its fractions on lipid accumulation was determined in 3T3-L1 cells using oil red O (ORO) staining. The expressions of AMP-activated protein kinase (AMPK) and adipogenic associated proteins [peroxisome proliferator-activated receptor-γ (PPAR-γ), CCAAT/enhancer-binding proteins α (C/EBP α), sterol regulatory element binding protein-1c (SREBP-1c), fatty acid synthase (FAS), and …
The Contributions Of Arterial Cross‑Sectional Area And Time‑Averaged Flow Velocity To Arterial Blood Flow, Ethan C. Hill, Terry J. Housh, Cory M. Smith, Josh L. Keller, Richard J. Schmidt, Glen O. Johnson
The Contributions Of Arterial Cross‑Sectional Area And Time‑Averaged Flow Velocity To Arterial Blood Flow, Ethan C. Hill, Terry J. Housh, Cory M. Smith, Josh L. Keller, Richard J. Schmidt, Glen O. Johnson
Department of Nutrition and Health Sciences: Faculty Publications
Background: Ultrasound has been used for noninvasive assessments of endothelial function in both clinical and athletic settings and to identify changes in muscle blood flow in response to exercise, nutritional supplementation, and occlusion. The purposes of the present study were to examine the reliability and relative contributions of arterial cross‑sectional area and time‑averaged flow velocity to predict muscle blood flow as a result of fatiguing exercise in men and women. Methods: Eighteen healthy men and 18 healthy women performed 50 consecutive eccentric repetitions of the elbow flexors at 60% of their pretest eccentric peak torque at a velocity of 180° …
Monitoring Energy Expenditure Using A Multi-Sensor Device—Applications And Limitations Of The Sensewear Armband In Athletic Populations, Karsten Koehler, Clemens Drenowatz
Monitoring Energy Expenditure Using A Multi-Sensor Device—Applications And Limitations Of The Sensewear Armband In Athletic Populations, Karsten Koehler, Clemens Drenowatz
Department of Nutrition and Health Sciences: Faculty Publications
In order to monitor their energy requirements, athletes may desire to assess energy expenditure (EE) during training and competition. Recent technological advances and increased customer interest have created a market for wearable devices that measure physiological variables and bodily movement over prolonged time periods and convert this information into EE data. This mini-review provides an overview of the applicability of the SenseWear armband (SWA), which combines accelerometry with measurements of heat production and skin conductivity, to measure total daily energy expenditure (TDEE) and its components such as exercise energy expenditure (ExEE) in athletic populations. While the SWA has been shown …
Stature, Body Mass, And Bmi In High School American Football Players: Appropriate Determinants Of Obesity Prevalence?, Alegra I. Mendez, Amelia A. Miramonti, Zachary M. Gillen, Brianna D. Mckay, Todd J. Leutzinger, Joel T. Cramer
Stature, Body Mass, And Bmi In High School American Football Players: Appropriate Determinants Of Obesity Prevalence?, Alegra I. Mendez, Amelia A. Miramonti, Zachary M. Gillen, Brianna D. Mckay, Todd J. Leutzinger, Joel T. Cramer
Department of Nutrition and Health Sciences: Faculty Publications
The purpose of this study was to evaluate stature (HT), weight (WT), body mass index (BMI), and obesity prevalence based on BMI categories in a large sample (n = 7,175) of high school American football players enrolled as freshmen, sophomores, or juniors. Players were categorized by their positions: offensive linemen (OL), defensive linemen (DL), tight end (TE), defensive end (DE), linebacker (LB), running back (RB), quarterback (QB), defensive back (DB), and wide receiver (WR). HT, WT, and BMI increased as grade increased among all positions. OL and DL had the greatest HT, WT, and BMI (p≤0.05). Obesity prevalence was greatest …
Integration Of Mirna And Mrna Expression Profles Reveals Microrna-Regulated Networks During Muscle Wasting In Cardiac Cachexia, Leonardo N. Moraes, Geysson J. Fernandez, Ivan Jose Vechetti Jr, Paula P. Freire, Rodrigo W. A. Souza, Rolando A.R. Villacis, Silvia R. Rogatto, Patricia P. Reis, Maeli Dal-Pai-Silvia, Robson F. Carvalho
Integration Of Mirna And Mrna Expression Profles Reveals Microrna-Regulated Networks During Muscle Wasting In Cardiac Cachexia, Leonardo N. Moraes, Geysson J. Fernandez, Ivan Jose Vechetti Jr, Paula P. Freire, Rodrigo W. A. Souza, Rolando A.R. Villacis, Silvia R. Rogatto, Patricia P. Reis, Maeli Dal-Pai-Silvia, Robson F. Carvalho
Department of Nutrition and Health Sciences: Faculty Publications
Cardiac cachexia (CC) is a common complication of heart failure (HF) associated with muscle wasting and poor patient prognosis. Although different mechanisms have been proposed to explain muscle wasting during CC, its pathogenesis is still not understood. Here, we described an integrative analysis between miRNA and mRNA expression profiles of muscle wasting during CC. Global gene expression profiling identified 1,281 genes and 19 miRNAs differentially expressed in muscle wasting during CC. Several of these deregulated genes are known or putative targets of the altered miRNAs, including miR-29a-3p, miR-29b-3p, miR-210-5p, miR-214, and miR-489. Gene ontology analysis on integrative mRNA/miRNA expression profiling …
Starch-Entrapped Microsphere Fibers Improve Bowel Habit But Do Not Exhibit Prebiotic Capacity In Those With Unsatisfactory Bowel Habits: A Phase I, Randomized, Double-Blind, Controlled Human Trial, Heather E. Rasmussen, Bruce Hamaker, Kumar B. Rajan, Ece Mutlu, Stefan J. Green, Michael Brown, Amandeep Kaur, Ali Keshavarzian
Starch-Entrapped Microsphere Fibers Improve Bowel Habit But Do Not Exhibit Prebiotic Capacity In Those With Unsatisfactory Bowel Habits: A Phase I, Randomized, Double-Blind, Controlled Human Trial, Heather E. Rasmussen, Bruce Hamaker, Kumar B. Rajan, Ece Mutlu, Stefan J. Green, Michael Brown, Amandeep Kaur, Ali Keshavarzian
Department of Nutrition and Health Sciences: Faculty Publications
Approximately one-third of individuals in the United States experience unsatisfactory bowel habits, and dietary intake, especially one low in fiber, could be partly responsible. We hypothesized that intake of a fermentable fiber (starch-entrapped microspheres, SM) that has a delayed, slow fermentation profile in vitro would improve bowel habit while exhibiting prebiotic capacity in those with self-described unsatisfactory bowel habits, all with minimal adverse effects. A total of 43 healthy volunteers completed a 3-month,double-blind, parallel-arm randomized clinical trial to assess the ability of a daily dose (9 or 12 g) of SM vs. psyllium (12 g) to improve bowel habit, including …
Dietary Red And Processed Meat Intake And Markers Of Adiposity And Inflammation: The Multiethnic Cohort Study, Weiwen Chai, Yukiko Morimoto, Robert V. Cooney, Adrian A. Franke, Yurii B. Shvetsov, Loïc Le Marchand, Christopher A. Haiman, Laurence N. Kolonel, Marc T. Goodman, Gertraud Maskarinec
Dietary Red And Processed Meat Intake And Markers Of Adiposity And Inflammation: The Multiethnic Cohort Study, Weiwen Chai, Yukiko Morimoto, Robert V. Cooney, Adrian A. Franke, Yurii B. Shvetsov, Loïc Le Marchand, Christopher A. Haiman, Laurence N. Kolonel, Marc T. Goodman, Gertraud Maskarinec
Department of Nutrition and Health Sciences: Faculty Publications
Objective—The potential influence of dietary factors on inflammation is important for cancer prevention. Utilizing data from control participants (312 men, 911 women) in two nested case-control studies of cancer within the Multiethnic Cohort, we examined the associations of red and processed meat intake with serum levels of leptin, adiponectin, C-reactive protein (CRP), tumor necrosis factor (TNF)-α, and interleukin (IL)-6 and the mediator effect of body mass index (BMI) on the above associations (if present).
Methods—Multivariable linear models were applied to assess the association between red and processed meat intake at cohort entry and serum biomarker levels measured 9.1 …
Relationships Between Nutrition-Related Knowledge, Self-Efficacy, And Behavior For Fifth Grade Students Attending Title I And Non-Title I Schools, Elisha M. Hall, Weiwen Chai, Julie A. Albrecht
Relationships Between Nutrition-Related Knowledge, Self-Efficacy, And Behavior For Fifth Grade Students Attending Title I And Non-Title I Schools, Elisha M. Hall, Weiwen Chai, Julie A. Albrecht
Department of Nutrition and Health Sciences: Faculty Publications
The Social Cognitive Theory (SCT) is a widely used theory for nutrition education programming. Better understanding the relationships between knowledge, self-efficacy, and behavior among children of various income levels can help to form and improve nutrition programs, particularly for socioeconomically disadvantaged youth. The purpose of this study was to determine the relationships between knowledge, self-efficacy, and behavior among fifth grade students attending Title I (≥ 40% of students receiving free or reduced school meals) and non-Title I schools (< 40% of students receiving free or reduced school meals). A validated survey was completed by 55 fifth grade students from Title I and 122 from non-Title I schools. Differences in knowledge, self-efficacy, and behavior scores between groups were assessed using t test and adjusted for variations between participating schools. Regression analysis was used to determine the relationships between knowledge, self-efficacy, and behavior. In adjusted models, the Title I group had significantly lower scores on several knowledge items and summary knowledge (P = 0.04). The Title I group had significantly lower scores on several behavior variables including intakes of fruits (P = 0.02), vegetables (P = 0.0005), whole grains (P = 0.0003), and lean protein (P = 0.047), physical activity (P = 0.002) and summary behavior (P = 0.001). However the Title I group scored higher on self-efficacy for meal planning (P = 0.04) and choosing healthy snacks (P = 0.036). Both self-efficacy (β = 0.70, P < 0.0001) and knowledge (β = 0.35, P = 0.002) strongly predicted behavior; however, only self-efficacy remained significant in the Title I group (self-efficacy, β = 0.82, P = 0.0003; knowledge, β = 0.11, P = 0.59). Results demonstrate disparities in nutrition knowledge and behavior outcomes between students surveyed from Title I and non-Title I schools, suggesting more resources may be necessary for lower income populations. Findings suggest that future nutrition interventions should focus on facilitating the improvement of children's self-efficacy
Athyrium Multidentatum (Doll.) Ching Extract Induce Apoptosis Via Mitochondrial Dysfunction And Oxidative Stress In Hepg2 Cells, Guoyuan Qi, Zhigang Liu, Rong Fan, Ziru Yin, Yashi Mi, Bo Ren, Xuebo Liu
Athyrium Multidentatum (Doll.) Ching Extract Induce Apoptosis Via Mitochondrial Dysfunction And Oxidative Stress In Hepg2 Cells, Guoyuan Qi, Zhigang Liu, Rong Fan, Ziru Yin, Yashi Mi, Bo Ren, Xuebo Liu
Department of Nutrition and Health Sciences: Faculty Publications
Athyrium multidentatum (Doll.) Ching (AMC), a unique and nutritious potherb widely distributed in china, has been extensively used in traditional Chinese medicine. Previous studies indicated that AMC extract exhibited antioxidant and antitumor properties. However, the chemical composition of AMC and molecular mechanism of AMC toxicity to HepG2 cells have not yet been elucidated. Hence, this study aimed to investigate the chemical compositions and the underlying mechanisms of the antiproliferative and apoptotic effects of AMC on HepG2. HPLC-MS analysis showed that AMC contain five compounds with chlorogenic acid accounting for 43 percent. Also, AMC strongly inhibited the cell growth and induced …
Atopic Dermatitis And Food Sensitization In South African Toddlers: Role Of Fiber And Gut Microbiota, Mahboobeh Mahdavinia, Heather Rasmussen, Phillip Engen, Jolice P. Van Den Berg, Erika Davis, Krista Engen, Stefan J. Green, Ankur Naqib, Maresa Botha, Claudia Gray, Nonhlanhla Lunjani, Carol Hlela, Wisdom Basera, Lelani Hobane, Alexandra Watkins, Mary C. Tobin, Alan Landay, Ali Keshavarzian, Michael E. Levin
Atopic Dermatitis And Food Sensitization In South African Toddlers: Role Of Fiber And Gut Microbiota, Mahboobeh Mahdavinia, Heather Rasmussen, Phillip Engen, Jolice P. Van Den Berg, Erika Davis, Krista Engen, Stefan J. Green, Ankur Naqib, Maresa Botha, Claudia Gray, Nonhlanhla Lunjani, Carol Hlela, Wisdom Basera, Lelani Hobane, Alexandra Watkins, Mary C. Tobin, Alan Landay, Ali Keshavarzian, Michael E. Levin
Department of Nutrition and Health Sciences: Faculty Publications
The pathogenesis of atopic dermatitis (AD) is complex and related to allergic responses and defects in skin barrier function. In common with many atopic diseases, the prevalence of AD has been increasing across the world.1 One of the theories for this increase is increased hygiene and urbanization-related changes in the environment, which can affect the human microbiome.2 Previous studies have found associations between the composition of the early gut microbiome and development of atopic conditions, including AD.3 Although the rate of atopic conditions, including AD and food allergy, is increasing on all continents, the prevalence of these diseases is still …
Aberrant Expression Of Microrna Induced By High-Fructose Diet: Implications In The Pathogenesis Of Hyperlipidemia And Hepatic Insulin Resistance, Nettu Sud, Hanyuan Zhang, Kaichao Pan, Xiao Cheng, Juan Cui, Qiaozhu Su
Aberrant Expression Of Microrna Induced By High-Fructose Diet: Implications In The Pathogenesis Of Hyperlipidemia And Hepatic Insulin Resistance, Nettu Sud, Hanyuan Zhang, Kaichao Pan, Xiao Cheng, Juan Cui, Qiaozhu Su
Department of Nutrition and Health Sciences: Faculty Publications
Fructose is a highly lipogenic sugar that can alter energy metabolism and trigger metabolic disorders. In the current study, microRNAs (miRNAs) altered by a high-fructose diet were comprehensively explored to elucidate their significance in the pathogenesis of chronic metabolic disorders. miRNA expression profiling using small noncoding RNA sequencing revealed that 19 miRNAs were significantly upregulated and 26 were downregulated in the livers of high-fructose-fed mice compared to chow-fed mice. Computational prediction and functional analysis identified 10 miRNAs, miR-19b-3p, miR-101a-3p, miR-30a-5p, miR-223-3p, miR-378a-3p, miR-33-5p, miR-145a-3p, miR-128-3p, miR-125b-5p and miR-582-3p, assembled as a regulatory network to potentially target key genes in lipid …
Milk Exosomes: Beyond Dietary Micrornas, Janos Zempleni
Milk Exosomes: Beyond Dietary Micrornas, Janos Zempleni
Department of Nutrition and Health Sciences: Faculty Publications
Extracellular vesicles deliver a variety of cargos to recipient cells, including the delivery of cargos in dietary vesicles from bovine milk to non-bovine species. The rate of discovery in this important line of research is slowed by a controversy whether the delivery and bioactivity of a single class of vesicle cargos, microRNAs, are real or not. This opinion paper argues that the evidence in support of the bioavailability of microRNAs encapsulated in dietary exosomes outweighs the evidence produced by scholars doubting that phenomenon is real. Importantly, this paper posits that the time is ripe to look beyond microRNA cargos and …
Association Between Energy Balance And Metabolic Hormone Suppression During Ultra-Endurance Exercise, Bjoern Geesmann, Jenna C. Gibbs, Joachim Mester, Karsten Koehler
Association Between Energy Balance And Metabolic Hormone Suppression During Ultra-Endurance Exercise, Bjoern Geesmann, Jenna C. Gibbs, Joachim Mester, Karsten Koehler
Department of Nutrition and Health Sciences: Faculty Publications
Ultra-endurance athletes often accumulate an energy deficit when engaging in ultra-endurance exercise, and upon completion of the exercise, they exhibit endocrine changes that are reminiscent of starvation. However, it remains unclear whether these endocrine changes are a result of the exercise per se or secondary to the energy deficit, and more importantly, whether these changes can be attenuated by increased dietary intake. Our goal was to assess the relationship between changes in key metabolic hormones following ultra-endurance exercise and measures of energy balance. Metabolic hormones as well as energy intake and expenditure were assessed in 14 well-trained male cyclists who …
The Effects Of Work-To-Rest Ratios On Torque, Electromyographic, And Mechanomyographic Responses To Fatiguing Workbouts, Ethan C. Hill, Terry J. Housh, Cory M. Smith, Kristen C. Cochrane, Nathaniel D.M. Jenkins, Richard J. Schmidt, Glen O. Johnson
The Effects Of Work-To-Rest Ratios On Torque, Electromyographic, And Mechanomyographic Responses To Fatiguing Workbouts, Ethan C. Hill, Terry J. Housh, Cory M. Smith, Kristen C. Cochrane, Nathaniel D.M. Jenkins, Richard J. Schmidt, Glen O. Johnson
Department of Nutrition and Health Sciences: Faculty Publications
The purpose of the present study was to examine the effects of 2 different work-to-rest ratios, but the same mean load, cycle time, and total duration of the exercise bout, on maximal voluntary isometric contraction torque and neuromuscular responses to fatiguing, intermittent, submaximal, isometric, forearm flexion muscle actions. Ten men performed 2 fatiguing protocols with different work-to-rest ratios (4 s contraction, 4 s rest vs. 4 s contraction, alternating 6 and 2 s rest) that consisted of 50 intermittent, submaximal (65% of maximal voluntary isometric contraction), isometric, forearm flexion muscle actions. Electromyographic and mechanomyographic signals from the biceps brachii were …
Prebiotics And Inflammatory Bowel Disease, Heather Rasmussen, Bruce R. Hamaker
Prebiotics And Inflammatory Bowel Disease, Heather Rasmussen, Bruce R. Hamaker
Department of Nutrition and Health Sciences: Faculty Publications
Inflammatory bowel disease risk factors include poor diet, and corresponding low intake of dietary fiber, specifically prebiotics, which is fermented by the gut microbiota. Dietary fibers, many of which are potential prebiotics, have hundreds to thousands of unique chemical structures that may promote bacteria or bacterial groups to provide beneficial health effects. In vitro and in vivo animal models provide some support for the use of prebiotics for inflammatory bowel disease through inflammation reduction. Studies using prebiotics in patients with inflammatory bowel disease are limited and focus on only a select few prebiotic substances.
Keywords: Inflammatory bowel disease, Ulcerative colitis, …
Evaluation Of A Dietary Screener: The Mediterranean Eating Pattern For Americans Tool, L. A. Cerwinske, Heather Rasmussen, S. Lipson, A. S. Volgman, Christy C. Tangney
Evaluation Of A Dietary Screener: The Mediterranean Eating Pattern For Americans Tool, L. A. Cerwinske, Heather Rasmussen, S. Lipson, A. S. Volgman, Christy C. Tangney
Department of Nutrition and Health Sciences: Faculty Publications
Background: Evidence exists for an association between accordance with a Mediterranean diet pattern and slower rates of cognitive decline. However, an ‘Americanized’ version of the Mediterranean diet screener is needed to assess accordance in the USA. Thus, the Mediterranean Eating Pattern for Americans (MEPA) tool was developed to assess accordance with a Mediterranean-like food pattern when time is limited. The present study aimed to determine whether the MEPA screener captured the key elements of the Mediterranean diet compared to the more comprehensive food frequency questionnaire (FFQ).
Methods: The study comprised a cross-sectional study in which 70 women completed both the …
Effects Of Fatigue And Recovery On Electromechanical Delay During Isokinetic Muscle Actions, Cory M. Smith, Terry J. Housh, Ethan C. Hill, Josh L. Keller, Glen O. Johnson, Richard J. Schmidt
Effects Of Fatigue And Recovery On Electromechanical Delay During Isokinetic Muscle Actions, Cory M. Smith, Terry J. Housh, Ethan C. Hill, Josh L. Keller, Glen O. Johnson, Richard J. Schmidt
Department of Nutrition and Health Sciences: Faculty Publications
Objective: To examine muscle-specific differences and the effects of fatigue and recovery on electromechanical delay (EMD) during maximal isokinetic muscle actions.
Approach: Thirteen men performed maximal isokinetic knee extension muscle actions at 60° s−1, pretest, posttest, and after 5 min of recovery from 25 maximal isokinetic knee extensions. The onsets of the electromyographic, mechanomyographic, and force signals were used to identify EMD measures from the vastus lateralis (VL), vastus medialis (VM), and rectus femoris (RF).
Main results: There were posttest increases in all EMD measures for all muscles that returned to pretest levels after 5 …
Less-Than-Expected Weight Loss In Normal-Weight Women Undergoing Caloric Restriction And Exercise Is Accompanied By Preservation Of Fat-Free Mass And Metabolic Adaptations, Karsten Koehler, M. J. De Souza, N. I. Williams
Less-Than-Expected Weight Loss In Normal-Weight Women Undergoing Caloric Restriction And Exercise Is Accompanied By Preservation Of Fat-Free Mass And Metabolic Adaptations, Karsten Koehler, M. J. De Souza, N. I. Williams
Department of Nutrition and Health Sciences: Faculty Publications
Background/Objectives: Normal-weight women frequently restrict their caloric intake and exercise, but little is known about the effects on body weight, body composition and metabolic adaptations in this population.
Subjects/Methods: We conducted a secondary analysis of data from a randomized controlled trial in sedentary normal-weight women. Women were assigned to a severe energy deficit (SEV: –1062 ± 80 kcal per day; n = 9), a moderate energy deficit (MOD: –633 ± 71 kcal per day; n = 7) or energy balance (BAL; n = 9) while exercising five times per week for 3 months. Outcome variables included changes in body weight, …
Parental Views Of Promoting Fruit And Vegetable Intake Among Overweight Preschoolers And School-Aged Children, Martha J. Nepper, Weiwen Chai
Parental Views Of Promoting Fruit And Vegetable Intake Among Overweight Preschoolers And School-Aged Children, Martha J. Nepper, Weiwen Chai
Department of Nutrition and Health Sciences: Faculty Publications
Given the importance of parental influence on children’s eating habits, we explored perceptions of parents of overweight (body mass index–for-age percentile ≥85%) preschoolers (3-5 years) and overweight school-aged children (6-12 years) regarding challenges in promoting fruit and vegetable intake and how they and other family members influence their overweight children’s dietary habits. Focus groups were conducted with 13 parents of overweight preschoolers and 14 parents of overweight school-aged children. Codes and themes were developed by inductive data analysis. Four common themes were identified: short shelf life of fresh fruits and vegetables prohibiting parents from purchasing, children’s taste changes in fruits …
Food Ingredients That Inhibit Cholesterol Absorption, Elliot D Jesch, Timothy P. Carr
Food Ingredients That Inhibit Cholesterol Absorption, Elliot D Jesch, Timothy P. Carr
Department of Nutrition and Health Sciences: Faculty Publications
Cholesterol is a vital component of the human body. It stabilizes cell membranes and is the precursor of bile acids, vitamin D and steroid hormones. However, cholesterol accumulation in the bloodstream (hypercholesterolemia) can cause atherosclerotic plaques within artery walls, leading to heart attacks and strokes. The efficiency of cholesterol absorption in the small intestine is of great interest because human and animal studies have linked cholesterol absorption with plasma concentration of total and low density lipoprotein cholesterol. Cholesterol absorption is highly regulated and influenced by particular compounds in the food supply. Therefore, it is desirable to learn more about natural …
Web-Based Interventions Alone Or Supplemented With Peer-Led Support Or Professional Email Counseling For Weight Loss And Weight Maintenance In Women From Rural Communities: Results Of A Clinical Trial, Patricia A. Hageman, Carol H. Pullen, Melody Hertzog, Bunny J. Pozehl, Christine Eisenhauer, Linda S. Boeckner
Web-Based Interventions Alone Or Supplemented With Peer-Led Support Or Professional Email Counseling For Weight Loss And Weight Maintenance In Women From Rural Communities: Results Of A Clinical Trial, Patricia A. Hageman, Carol H. Pullen, Melody Hertzog, Bunny J. Pozehl, Christine Eisenhauer, Linda S. Boeckner
Department of Nutrition and Health Sciences: Faculty Publications
Objective. This trial compared the effectiveness of a web-based only (WO) intervention with web-based supplemented by peer-led discussion (WD) or professional email counseling (WE) across 3 phases to achieve weight loss and weight maintenance in women from underserved rural communities.
Methods. 301 women (BMI of 28–45 kg/m2) randomly assigned to groups participated in guided weight loss (baseline to 6 months), guided weight loss and maintenance (6 to 18 months), and self-managed weight maintenance (18 to 30 months).
Results. Retention was 88.7%, 76.5%, and 71.8% at 6, 18, and 30 months, respectively. Intent-to-treat analyses demonstrated no group …
Reliability And Minimum Detectable Change For Common Clinical Physical Function Tests In Sarcopenic Men And Women, Nathaniel D.M. Jenkins, Joel T. Cramer
Reliability And Minimum Detectable Change For Common Clinical Physical Function Tests In Sarcopenic Men And Women, Nathaniel D.M. Jenkins, Joel T. Cramer
Department of Nutrition and Health Sciences: Faculty Publications
Objectives: To determine the test–retest reliability and minimum detectable change scores for seven common clinical measurements of muscle strength and physical function in a multiethnic sample of sarcopenic, malnourished men and women.
Design: Each participant visited the laboratory seven times over 25 to 26 weeks. Reliability was assessed for each measurement from Familiarization 1 to Familiarization 2 (R1), Familiarization 2 to baseline testing (R2), Familiarization 3 to 12-week testing (R3), and Familiarization 4 to 24-week testing (R4).
Setting: Data were collected during a clinical trial at 23 sites in the United States, Belgium, Italy, Mexico, Poland, Spain, Switzerland, and the …