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Molecular, Genetic, and Biochemical Nutrition Commons™
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Articles 1 - 2 of 2
Full-Text Articles in Molecular, Genetic, and Biochemical Nutrition
The Effect Of Wild Blueberry Bioactives On Endothelial Cell Migration And Angiogenesis: An In Vitro Mechanistic, Genomic And Proteomic Approach, Panagiotis Tsakiroglou
The Effect Of Wild Blueberry Bioactives On Endothelial Cell Migration And Angiogenesis: An In Vitro Mechanistic, Genomic And Proteomic Approach, Panagiotis Tsakiroglou
Electronic Theses and Dissertations
The goal of this study is to investigate the effects of wild blueberry fractions (Anthocyanins and Phenolic acids) on vascular function and physiology. More specifically the potential effects of the above fractions and their combination in physiological concentrations on endothelial cell migration, angiogenesis, gene expression and proteins synthesis of markers related to the above processes. The objectives are to study whether anthocyanins, phenolic acids and their combinations (ACNs:PAs) affect: a) cell proliferation, b) speed of endothelial cell migration, c) angiogenesis, d) gene expression of genes critical for cell migration and angiogenesis such as RAC1, RHOA, AKT1, eNOS and VEGF and …
Cancer Chemoprevention By Dietary Compounds Targeting Angiogenesis, Wasamon Nutakul
Cancer Chemoprevention By Dietary Compounds Targeting Angiogenesis, Wasamon Nutakul
Doctoral Dissertations
Cancer remains a leading cause of death worldwide. Due to angiogenesis and metastatic potency of cancer, chemotherapies are not adequate for metastatic tumor. We investigated anti-carcinogenic effects of resveratrol in comparison to those of pterostilbene in colon cancer cells. We found superior activities of pterostilbene over resveratrol in growth inhibition as well as apoptosis induction. Higher Intracellular concentration of pterostilbene could contribute to its higher potency in anti-carcinogenesis; however, both resveratrol and pterostilbene failed to inhibit colon cancer cell migration in vitro. Polymethoxylatedflavones (PMFs) found exclusively in citrus fruits have shown inhibitory effects against cancer. We investigated their anti-angiogenic …