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2023

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Articles 331 - 360 of 361

Full-Text Articles in Nutrition

Commentary: Effect Evaluation Of Sahtak Bi Sahnak, A Lebanese Secondary School-Based Nutrition Intervention: A Cluster Randomised Trial, Abu Bakkar Siddique, Andrew W Brown, Lilian Golzarri-Arroyo, David B Allison Jan 2023

Commentary: Effect Evaluation Of Sahtak Bi Sahnak, A Lebanese Secondary School-Based Nutrition Intervention: A Cluster Randomised Trial, Abu Bakkar Siddique, Andrew W Brown, Lilian Golzarri-Arroyo, David B Allison

Children’s Nutrition Research Center Staff Publications

No abstract provided.


Curriculum Strategy To Increase College Student’S Motivation, Ability And Opportunity Resulting In Reduction In Wasted Food, Sarah D. Brunnig Jan 2023

Curriculum Strategy To Increase College Student’S Motivation, Ability And Opportunity Resulting In Reduction In Wasted Food, Sarah D. Brunnig

UNF Graduate Theses and Dissertations

Concerns about Food Loss and Waste (FLW) have been rapidly growing worldwide as it came to be understood how the loss of about one-third of the edible food produced globally leads to environmental damage, leads to loss of about USD 1 trillion and keeps food from hungry people. Consumers in developed countries account for the largest majority of food that is wasted. College presents an excellent opportunity to reach young adults as they are developing their identity, self-efficacy and life skills. Utilizing the Motivation-Ability-Opportunity Framework, this research’s overall goal was to find a Curriculum Strategy to engage allied health students …


The Impact Of Universal Free Meals During Covid-19 On Family Life And Perspective Of School Meals In Central Washington State, Charlotte Green Jan 2023

The Impact Of Universal Free Meals During Covid-19 On Family Life And Perspective Of School Meals In Central Washington State, Charlotte Green

All Master's Theses

This study explored the impact of the USDA COVID-19 Universal Free Meal (UFM) waivers on family life, school meal participation, and child eating habits from parents with children in Central Washington state (WA) schools. n = 119 parents/caregivers with students who were in K-12th grade in Central WA from August 2019-February 2023 completed a 10 question electronic, and descriptive survey. The survey measured changes in participation in school lunch/breakfast pre to post COVID-19 waiver, which provided free meals for all children, and whether UFM were beneficial to families, impacted perception of school food, child’s sense of community at school …


The Inverse Association Between Prebiotic Consumption And Depression Status In American Adult Females, But Not The Greater Population Or In Males: Nhanes 2015-2018, Cassandra L. Boyd Jan 2023

The Inverse Association Between Prebiotic Consumption And Depression Status In American Adult Females, But Not The Greater Population Or In Males: Nhanes 2015-2018, Cassandra L. Boyd

Master's Theses

It is unknown if a relationship exists between prebiotic intake and depression status. Using 2015-2018 National Health and Nutrition Examination Survey cycles data, adult American estimated mean daily prebiotic intake across demographic groups, gender, and depression status were reported. Additionally, the 10 highest prebiotic content Food and Nutrient Database for Dietary Studies foods were identified. Adults (≥ 18 years) with adequate sleep and at least one day of dietary recall data were included. Participants with excessive alcohol intake, BMI ≤ 18, BMI ≥ 30, or current depression medication use were excluded. The confounding variables were inadequate sleep, unemployment, and age. …


Addition Of Apple Pomace To Feeding Substrate On Growth, Development, And Survival Rates Of Yellow Mealworms (Tenebrio Molitor) And Characterization Of Their Proteins Extracted By A Ph-Shift Process, Michelle Duvall Jan 2023

Addition Of Apple Pomace To Feeding Substrate On Growth, Development, And Survival Rates Of Yellow Mealworms (Tenebrio Molitor) And Characterization Of Their Proteins Extracted By A Ph-Shift Process, Michelle Duvall

Graduate Theses, Dissertations, and Problem Reports (ETD)

The weight changes, survival/mortality rates, and proximate compositions of Tenebrio molitor (yellow mealworm) larvae whose diets were supplemented with apple pomace were analyzed after a 4-week feeding study to examine the nutritional quality of the insects for use as a future potential food source. Going forward, the terms “mealworm(s)”, "yellow mealworm(s)”, “T. molitor” will be used interchangeably and will always refer to the same species. The mealworm larvae were randomly divided into two groups: in addition to standard worm chow, one group was given 15 g/week of non-nutritive water-storing polymer crystals and the other was given apple pomace …


Food Fan Academy: Boosting Informal Educators Abilities To Use Food As A Teaching Tool, Kelly Furr Jan 2023

Food Fan Academy: Boosting Informal Educators Abilities To Use Food As A Teaching Tool, Kelly Furr

Graduate Research Theses & Dissertations

Introduction: Food, fitness, and nutrition (FAN) professional development (PD) for informal educators can serve to impact science, technology, engineering, art, mathematics, and medicine (STEAM+M) learning environments. Using food as a teaching tool in shaping the development of informal educators and education of students offers a unique opportunity for the acquisition of scientific knowledge and essential skills. The purpose of this study was to develop a Food FAN Academy for informal educators and evaluate the effectiveness of the PD. Methods: Case study method was utilized for the research study and the Food FAN Academy PD was a two-hour session designed in …


Effectiveness Of The Catch (Coordinated Approach To Child’S Health) Rainbow Program In Elementary Schools For Change In Fruit And Vegetable Intake, Ashley M. Valinskas Jan 2023

Effectiveness Of The Catch (Coordinated Approach To Child’S Health) Rainbow Program In Elementary Schools For Change In Fruit And Vegetable Intake, Ashley M. Valinskas

Graduate Research Theses & Dissertations

Background: There is currently a lack of nutrition education programs that effectively increase fruit and vegetable (FV) intake among children. Not meeting the recommendations for fruits and vegetables increases the risk for poor academic achievement, obesity, and chronic diseases such as cardiovascular disease, type II diabetes, asthma, and more. Nutrition, cooking, and gardening lessons individually and together have shown to increase fruit and vegetable (FV) consumption in school-aged children.Methods: Two-Hundred Twenty-five 4th and 5th graders participated in six cooking and six gardening lessons between September 2021 and May 2022 at Genoa Elementary school. Each nutrition education session was 25-minutes long, …


Site-Specific Analysis Of The Incidence Rate Of Enterotoxigenic Escherichia Coli Infection Elucidates An Association With Childhood Stunting, Wasting, And Being Underweight: A Secondary Analysis Of The Mal-Ed Birth Cohort, Ahshanul Haque, Sabiha Nasrin, Parag Palit, Rina Das, Barbie Zaman Wahid, Amran Gazi, Mustafa Mahfuz, Abu Syed Golam Faruque, Tahmeed Ahmed Jan 2023

Site-Specific Analysis Of The Incidence Rate Of Enterotoxigenic Escherichia Coli Infection Elucidates An Association With Childhood Stunting, Wasting, And Being Underweight: A Secondary Analysis Of The Mal-Ed Birth Cohort, Ahshanul Haque, Sabiha Nasrin, Parag Palit, Rina Das, Barbie Zaman Wahid, Amran Gazi, Mustafa Mahfuz, Abu Syed Golam Faruque, Tahmeed Ahmed

Department of Nutrition and Health Sciences: Faculty Publications

Asymptomatic infection by fecal enteropathogens is a major contributor to childhood malnutrition. Here, we investigated the incidence rate of asymptomatic infection by enterotoxigenic Escherichia coli (ETEC) and assessed its association with childhood stunting, wasting, and being underweight among children under 2 years of age. The Malnutrition and Enteric Disease birth cohort study included 1,715 children who were followed from birth to 24 months of age from eight distinct geographic locations including Bangladesh, Brazil, India, Peru, Tanzania, Pakistan, Nepal, and South Africa. The TaqMan array card assay was used to determine the presence of ETEC in the nondiarrheal stool samples collected …


Contents, Discovery Editors Jan 2023

Contents, Discovery Editors

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

No abstract provided.


Featured Faculty Mentor/Student Team, Gisela Erf, Alessandro Rocchi Jan 2023

Featured Faculty Mentor/Student Team, Gisela Erf, Alessandro Rocchi

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

No abstract provided.


Temporal, Phenotypic, And Quantitative Characterization Of Thyroid Infiltrating Mononuclear Cells During Development Of Spontaneous Autoimmune Thyroiditis In Obese Strain Chickens, Katelyn M. Clark, Chrysta N. Beck, Gisela F. Erf Jan 2023

Temporal, Phenotypic, And Quantitative Characterization Of Thyroid Infiltrating Mononuclear Cells During Development Of Spontaneous Autoimmune Thyroiditis In Obese Strain Chickens, Katelyn M. Clark, Chrysta N. Beck, Gisela F. Erf

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

The Obese strain (OS) of chickens spontaneously develops autoimmune thyroiditis (SAT) and is a well-established biomedical model for Hashimoto’s thyroiditis in humans. Both conditions are characterized by the infiltration of thyroid glands with mononuclear immune cells resulting in the destruction of thyroid tissue and impairment of the thyroid’s endocrinological functions. Past studies described immune cell infiltration in thyroids of the OS chickens, but the time-course, cell composition, and relative amounts of the various immune cells infiltrating the thyroids have not been well defined. In this project, frozen and stored thyroid glands that were previously collected at 1, 4, 7, 14, …


Determining The Effectiveness Of Rosemary Essential Oil On The Shelf Life Of Ground Beef Under Different Lighting Conditions, Jordan T. Looper, Kelly R. Vierck Jan 2023

Determining The Effectiveness Of Rosemary Essential Oil On The Shelf Life Of Ground Beef Under Different Lighting Conditions, Jordan T. Looper, Kelly R. Vierck

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

This study determined the effectiveness of rosemary extract on the shelf life of ground beef patties under different retail display conditions. Ground beef patties were produced from an 85%:15% blend (lean:fat). Patties were formed from batches of control or amended with rosemary extract. Patties were individually packaged using overwrap. Groups were assigned into one of two lighting groups (3000K and 3500K). Patties were placed in a simulated retail display for 5 d under continuous lighting and rotated once a day. Lipid oxidation and color samples were taken each day. Relating to lipid oxidation, there was no three-way interaction between display …


Instructions For Authors, Discovery Editors Jan 2023

Instructions For Authors, Discovery Editors

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

No abstract provided.


Sustainability Practices In Aquaculture: Using Algae Turf Scrubber Biomass To Raise Black Soldier Flies As An Alternative Feed In Blue Tilapia, Oreochromis Aureus, Culture, Michelle C. Lowery Jan 2023

Sustainability Practices In Aquaculture: Using Algae Turf Scrubber Biomass To Raise Black Soldier Flies As An Alternative Feed In Blue Tilapia, Oreochromis Aureus, Culture, Michelle C. Lowery

College of Graduate Studies: Theses & Dissertations

Since the 1980s, non-algal aquaculture has grown to encompass 49% of all seafood production in response to a growing human population and increased seafood demand (FAO, 2022). Hurdles exist to aquaculture sustainability, including dependence on wild sourced fishmeal (FM) and the impacts wastewater discharge. It takes 4-5 tons of wild forage fish to produce one ton of dry FM (Miles and Chapman, 2006) and as aquaculture is primarily conducted in earthen ponds and public open water bodies (FAO, 2022), finfish culture can have a high impact on the surrounding environment by discharging excess nutrients. This study used algae turf scrubber …


A Coalition-Driven Examination Of Organization Capacity To Address Food Insecurity In Greater Houston: A Qualitative Research Study, Jemima C John, Jennifer Gonzalez, Sara-Grace Chan, Heidi Mcpherson, Jennifer N Aiyer, Esperanza Galvan, Nicole Browning, Shreela V Sharma Jan 2023

A Coalition-Driven Examination Of Organization Capacity To Address Food Insecurity In Greater Houston: A Qualitative Research Study, Jemima C John, Jennifer Gonzalez, Sara-Grace Chan, Heidi Mcpherson, Jennifer N Aiyer, Esperanza Galvan, Nicole Browning, Shreela V Sharma

Faculty, Staff and Student Publications

BACKGROUND: Economic and social hardships have worsened food insecurity, particularly among low income and racial-ethnic minority groups. Given the core goal of the 150+ member Houston Health Equity Collective (HEC) to reduce food insecurity by 5% in 2025, we explored member organizations' capacity and challenges faced in screening and responding to food insecurity through care coordination efforts.

METHODS: A twice-administered Qualtrics XM survey (Provo, Utah) with 76 organizations, followed by five focus groups with 22 of these organizations, explored reach and response efforts to food insecurity. Qualitative assessments lasted between 0.5 to 1.5 h, were audio-recorded, cleaned, coded, and thematically …


Examining Neighborhood-Level Hot And Cold Spots Of Food Insecurity In Relation To Social Vulnerability In Houston, Texas, Ryan Ramphul, Linda Highfield, Shreela Sharma Jan 2023

Examining Neighborhood-Level Hot And Cold Spots Of Food Insecurity In Relation To Social Vulnerability In Houston, Texas, Ryan Ramphul, Linda Highfield, Shreela Sharma

Faculty, Staff and Student Publications

Food insecurity is prevalent and associated with poor health outcomes, but little is known about its geographical nature. The aim of this study is to utilize geospatial modeling of individual-level food insecurity screening data ascertained in health care settings to test for neighborhood hot and cold spots of food insecurity in a large metropolitan area, and then compare these hot spot neighborhoods to cold spot neighborhoods in terms of the CDC's Social Vulnerability Index. In this cross-sectional secondary data analysis, we geocoded the home addresses of 6,749 unique participants screened for food insecurity at health care locations participating in CMS's …


Effects Of Weight Bias Internalization On Disordered Eating, Dieting, And Intuitive Eating In College Students, Stacia Tietje Jan 2023

Effects Of Weight Bias Internalization On Disordered Eating, Dieting, And Intuitive Eating In College Students, Stacia Tietje

Graduate Research Theses & Dissertations

Weight bias internalization (WBI) is the tendency to blame oneself for negative weight-based stereotypes and external influences. WBI has been shown to have negative effects on both physical and mental health. The purpose of this study is to examine the association between WBI, disordered eating, and dieting and whether intuitive eating moderates these relationships in a sample of college students. This study utilized a cross-sectional survey design to gather quantitative data. College undergraduate students (N = 652) from a Midwestern university were recruited via email. Data were analyzed in SPSS, using descriptive statistics, multiple linear regression, ordinal, and binary logistic …


Role Of Human Gut Microbiota In Shaping The Diet-Induced Metabolome, Samitinjaya Dhakal Jan 2023

Role Of Human Gut Microbiota In Shaping The Diet-Induced Metabolome, Samitinjaya Dhakal

Electronic Theses and Dissertations

No abstract provided.


Nutrient Intakes, Compliance With Recommendations And Key Sources In Women Of Child-Bearing Age (18-50 Y) In Ireland, Abigail O' Mahony Jan 2023

Nutrient Intakes, Compliance With Recommendations And Key Sources In Women Of Child-Bearing Age (18-50 Y) In Ireland, Abigail O' Mahony

Theses

Women’s pre-conceptional health (including nutritional status) is important for both the health of the individual themselves and also for the lifelong health of any occurring offspring. However, it has been estimated that up to 50% of pregnancies are unplanned, thus optimal nutritional status is important for all women of child-bearing age (WCBA) not just those with pregnancy intentions. Despite the accumulation of evidence of the importance of nutritional status at this life-stage, nutrient recommendations for WCBA for the most part don’t differ from recommendations for other population groups. The notable exception to this is that all WCBA are recommended to …


Palatability, Consumption, And Physiological Effects Of The Green Microalgae Chlorella Sp. As A Feed Substitute For The Western Honey Bee Apis Mellifera In A Laboratory Setting, Benjamin J. Nichols Jan 2023

Palatability, Consumption, And Physiological Effects Of The Green Microalgae Chlorella Sp. As A Feed Substitute For The Western Honey Bee Apis Mellifera In A Laboratory Setting, Benjamin J. Nichols

Department of Entomology: Distance Master of Science Projects

Western honey bees Apis mellifera are vital pollinators which play a significant role in global food security. Honey bees are faced by numerous environmental pressures including lack of forage which lead to large losses annually of managed honeybee colonies. To offset these pressures, many beekeepers manage colonies with the addition of artificial diets, many of which contain products that do not meet the nutritional requirements needed by honey bees or require large amounts of resources to grow. Recent literature has indicated that algae may be a viable nutritional resource for honey bees, meeting the nutritional requirements needed, requiring less resources, …


Site-Specific Incidence Rate Of Blastocystis Hominis And Its Association With Childhood Malnutrition: Findings From A Multi-Country Birth Cohort Study, Barbie Zaman Wahid, Ahshanul Haque, Amran Gazi, Shah Mohammad Fahim, Abu Syed Golam Faruque, Mustafa Mahfuz, Tahmeed Ahmed Jan 2023

Site-Specific Incidence Rate Of Blastocystis Hominis And Its Association With Childhood Malnutrition: Findings From A Multi-Country Birth Cohort Study, Barbie Zaman Wahid, Ahshanul Haque, Amran Gazi, Shah Mohammad Fahim, Abu Syed Golam Faruque, Mustafa Mahfuz, Tahmeed Ahmed

Department of Nutrition and Health Sciences: Faculty Publications

In this study, we investigated the potential association between the burden of asymptomatic Blastocystis spp. (Blastocystis hominis) infection and nutritional status among children under 2 years of age using the data collected from 1,715 children from eight distinct geographic locations, including Bangladesh, Brazil, India, Peru, Tanzania, Pakistan, Nepal, and South Africa. Childhood stunting, wasting, and underweight were the outcome variables, and B. hominis infection was the exposure variable of this present study. The presence of B. hominis in nondiarrheal stools was evaluated by TaqMan Array Cards. Site-specific incidence rates were estimated using Poisson regression, and multiple generalized estimating …


The Paradox Of Child Poverty And Welfare, Tirna Purkait Jan 2023

The Paradox Of Child Poverty And Welfare, Tirna Purkait

Department of Nutrition and Health Sciences: Faculty Publications

The United States confronts persistent child welfare issues rooted in poverty. The age-old debate vacillates between advocating personal responsibility and bolstering social safety nets. Current welfare programs, aiming to mitigate child poverty, often fall short given the deep nexus of poverty and child maltreatment. This paper probes the intricate ties between child poverty and welfare, emphasizing state legislative variances, inherent system paradoxes, and potential policy enhancements. Exploring historical contexts, existing societal frameworks, and future reforms, this research emphasizes the urgency for all-encompassing solutions. These should tackle poverty’s core while fortifying child welfare, safeguarding the well-being of forthcoming American generations.


Relationship Between Reproductive And Bone Biomarkers And Osteoarthritis In Zoo Asian (Elephas Maximus) And African (Loxodonta Africana) Elephants, Daniella E Chusyd, Janine L Brown, Lilian Golzarri-Arroyo, Stephanie L Dickinson, Virginia B Kraus, Jessica Siegal-Willott, Timothy M Griffin, Janet L Huebner, Katie L Edwards, David B Allison, Steven N Austad Jan 2023

Relationship Between Reproductive And Bone Biomarkers And Osteoarthritis In Zoo Asian (Elephas Maximus) And African (Loxodonta Africana) Elephants, Daniella E Chusyd, Janine L Brown, Lilian Golzarri-Arroyo, Stephanie L Dickinson, Virginia B Kraus, Jessica Siegal-Willott, Timothy M Griffin, Janet L Huebner, Katie L Edwards, David B Allison, Steven N Austad

Children’s Nutrition Research Center Staff Publications

Osteoarthritis (OA) is common in zoo Asian (Elephas maximus) and African (Loxodonta africana) elephants. This study investigated the relationship between confirmed or suspected OA with ovarian cyclicity, gonadotropins, progestagens, luteinizing hormone (LH), follicular stimulating hormone (FSH), and collagen type I (CTX-I) in zoo elephants. In Asian elephants, odds of having confirmed or suspected OA decreased with cycling (OR = 0.22, P = 0.016; OR = 0.29, P = 0.020, respectively), however, not when adjusted for age (odds ratio [OR] = 0.31, P = 0.112; OR = 0.58, P = 0.369, respectively). In African elephants, none of …


Conditioning On Parental Mating Types Can Reduce Necessary Assumptions For Mendelian Randomization, Keisuke Ejima, Nianjun Liu, Luis Miguel Mestre, Gustavo De Los Campos, David B Allison Jan 2023

Conditioning On Parental Mating Types Can Reduce Necessary Assumptions For Mendelian Randomization, Keisuke Ejima, Nianjun Liu, Luis Miguel Mestre, Gustavo De Los Campos, David B Allison

Children’s Nutrition Research Center Staff Publications

Mendelian randomization (MR) has become a common tool used in epidemiological studies. However, when confounding variables are correlated with the instrumental variable (in this case, a genetic/variant/marker), the estimation can remain biased even with MR. We propose conditioning on parental mating types (a function of parental genotypes) in MR to eliminate the need for one set of assumptions, thereby plausibly reducing such bias. We illustrate a situation in which the instrumental variable and confounding variables are correlated using two unlinked diallelic genetic loci: one, an instrumental variable and the other, a confounding variable. Assortative mating or population admixture can create …


Development Of Probiotic Fermented Beverage From Gac Fruit (Momordica Cochinchinensis) And Its Functional Properties On Gut Health, Marisa Marnpae Jan 2023

Development Of Probiotic Fermented Beverage From Gac Fruit (Momordica Cochinchinensis) And Its Functional Properties On Gut Health, Marisa Marnpae

Chulalongkorn University Theses and Dissertations (Chula ETD)

The study aimed to develop a probiotic beverage using gac fruit and assess its characteristics and functional properties related to gut health through probiotic lactic acid fermentation. Gac juice (GJ) at 5–10 g/100 g was fermented with Lactobacillus paracasei subsp. paracasei (L. CASEI 431®), and various aspects were explored, including probiotic viability, physicochemical properties, phytochemicals, antioxidant activity, functional properties, volatile flavor compounds, and sensory acceptability of fermented GJ (FGJ). The results indicated a decrease in pH and sugar content, alongside an increase in lactic acid, acetic acid, and probiotic viability, up to 108 CFU/mL, post-fermentation. Notably, FGJ, particularly at 10 …


Probiotic Beverage From Different Cultivars Of Pomelo Juices (Citrus Grandis (L.) Osbeck) Fermented With Lactobacillus Spp., Vernabelle Balmori Jan 2023

Probiotic Beverage From Different Cultivars Of Pomelo Juices (Citrus Grandis (L.) Osbeck) Fermented With Lactobacillus Spp., Vernabelle Balmori

Chulalongkorn University Theses and Dissertations (Chula ETD)

Pomelo fruit contains prebiotic and bioactive components which makes it a promising substrate for non-dairy probiotic beverages. The study investigated the potential of fermenting five pomelo cultivars with Lactobacillus paracasei for non-dairy probiotic beverages. Fermentation enhanced lactic acid bacteria (8.80–9.28 log CFU/ml), organic acids, polyphenols, flavonoids, and antioxidant activity, disrupting cholesterol micellization and inhibiting pancreatic lipase. Some cultivars showed improved volatile compounds and sensory scores post-fermentation. Tubtim Siam exhibited the highest functionality and health benefits based on principal component analysis and hierarchical clustering and was used for further analysis for beneficial effects. The in-vitro colonic fermentation of fermented and non-fermented …


Role Of Grb2 Intracellular Localization In Progesterone Receptor Positive Breast Cancer, Nattamolphan Wittayavimol Jan 2023

Role Of Grb2 Intracellular Localization In Progesterone Receptor Positive Breast Cancer, Nattamolphan Wittayavimol

Chulalongkorn University Theses and Dissertations (Chula ETD)

Progesterone receptor (PR) extranuclear signaling mediates mainly through PR polyproline domain (PPD) interaction with SH3 domain of cytoplasmic signaling molecules. PR-PPD interfered with Grb2-SOS binding through SH3 interaction resulting in decreased cell proliferation and correlates with a good prognosis in PR positive breast cancer. Grb2 is a key adaptor molecule and expressed in both nucleus and cytoplasm. We hypothesized that change in Grb2 localization alters PR transcription resulting in better clinical outcomes in PR positive breast cancer. BT-474 breast cancer cells expressing inducible Grb2-SV402x (nuclear Grb2, nuGrb2) or Grb2-MYR (membrane Grb2, memGrb2) were constructed. MemGrb2-BT-474 showed higher levels of PR …


Roles Of Progesterone Signaling On Dna Repair And Cell Survival In Ovarian Cancer Cells, Pattarasiri Rangsrikitphoti Jan 2023

Roles Of Progesterone Signaling On Dna Repair And Cell Survival In Ovarian Cancer Cells, Pattarasiri Rangsrikitphoti

Chulalongkorn University Theses and Dissertations (Chula ETD)

Every year over 300,000 women worldwide are diagnosed with ovarian cancer and half of these patients die from this disease. The symptoms of ovarian cancer are very general and often confused with other common female diseases making ovarian cancer a challenging disease to diagnose and treat. Platinum-based chemotherapy, including cisplatin, stands as the first-line treatment for ovarian cancer. However, chemotherapy resistance remains a continuing problem, contributing to a high mortality rate. Progesterone receptor (PR) signaling has been implicated in various aspects of ovarian cancer biology. Clinical studies show a positive correlation between PR expression, improved patient survival and cisplatin response, …


“Anything From The Land Is Good”: Understanding How Community Gardening In Kakisa, Northwest Territories, Can Contribute To Indigenous Food Sovereignty, Michelle Malandra Jan 2023

“Anything From The Land Is Good”: Understanding How Community Gardening In Kakisa, Northwest Territories, Can Contribute To Indigenous Food Sovereignty, Michelle Malandra

Theses and Dissertations (Comprehensive)

Rates of food insecurity in Canada’s northern Indigenous communities are at levels that should constitute an emergency. Dominant explanations for these high rates of food insecurity often ignore the ongoing impacts of colonization and over-emphasize individual choices and nutritional guidelines developed by outsiders. The importance of holistic community health is ignored, along with the cultural and social values and practices that support community health and well-being, including traditional food systems. As the acute impact of climate change in the North threatens traditional food access, a shift toward an Indigenous food sovereignty approach in health and food policy is needed. With …


The Relationship Between Alpha-Defensin 1 And Gut Microbiome Composition In A Population Of Bhutanese Refugee Adults With A High Prevalence Of Type 2 Diabetes, Daisha Alana Drake Jan 2023

The Relationship Between Alpha-Defensin 1 And Gut Microbiome Composition In A Population Of Bhutanese Refugee Adults With A High Prevalence Of Type 2 Diabetes, Daisha Alana Drake

Honors Theses and Capstones

The New Hampshire Bhutanese refugee population is disproportionately affected by obesity and metabolic disorders such as type 2 diabetes. The gut microbiome is important for overall human health, with high microbial richness and diversity being associated with reduced chronic inflammation and type 2 diabetes risk. Microbial richness and diversity have been shown to decrease in United States (U.S.) immigrant populations, but have not been measured in refugee populations. One of the anti-inflammatory functions of the gut microbiome is related to the production of short-chain fatty acids (SCFAs), which regulate pro-inflammatory cytokine production. Alpha-defensin 1 is an antimicrobial peptide that is …