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Articles 211 - 240 of 254
Full-Text Articles in Nutrition
Can Student-Driven Changes Increase Salad Bar Usage In Schools?, Shannon Leeke
Can Student-Driven Changes Increase Salad Bar Usage In Schools?, Shannon Leeke
Electronic Theses and Dissertations
Increasing student salad bar participation may increase students' consumption of fruits and vegetables while decreasing their risk of chronic disease. This study observed student perception, experience, and participation of the school salad bar in two northwest Mississippi high schools. The subjects were students' age 15-18 years old. One school served as the control variable and one served as the intervention variable. A three-week baseline of salad bar participation was collected before surveying students at the intervention school. Surveying student perception and experience of the salad bar provided data to implement changes to the salad bar. Student perception and experience was …
Compare Effects Of Diets Made With Different Saturated Fatty Acids On Body Weight Regulation And Metabolism In Wister Rats, Dilruba Fatema
Compare Effects Of Diets Made With Different Saturated Fatty Acids On Body Weight Regulation And Metabolism In Wister Rats, Dilruba Fatema
Wayne State University Theses
Animal fats are known to cause elevated blood total and low-density- lipoprotein (LDL) cholesterol levels in humans and animals. This study was designed to investigate the effects of both the quality (coconut oil and a modified beef tallow with reduced saturated fatty acid content) and quantity (low and high) of dietary fat in body weight regulation and alteration of blood cholesterol levels in an animal model. Forty two male Wister rats were randomly divided into 4 groups: Control Low Fat (CLF, n=10), Control High Fat (CHF, n=10), Modified Low Fat (MLF, n=11), and Modified High Fat (MLF, n=11). They were …
Comparative Phenolic Content And Antioxidant Activities Of Blueberry (Vaccinium Corymbosum) Afected By In Vitro Digestion, Sonia Gharbi
Comparative Phenolic Content And Antioxidant Activities Of Blueberry (Vaccinium Corymbosum) Afected By In Vitro Digestion, Sonia Gharbi
Wayne State University Theses
Abstract
COMPARATIVE PHENOLIC CONTENT AND ANTIOXIDANT ACTIVITIES OF BLUEBERRY (VACCINIUM CORYMBOSUM) AFECTED BY IN VITRO DIGESTION
By
SONIA GHARBI
May 2014
Adviser: Dr. Kevin Zhou
Major: Nutrition and Food Science
Degree: Master of Science
The biological properties of antioxidants depend on their release from the food matrix during the digestion process. Blueberry contains a wide range of phenolic compounds which are of great significance due to their antioxidant activity. In vitro digestion is a rapid and inexpensive method used to determine the availability of nutrients involved in the absorption studies with humans. Total phenolic content and antioxidant activity of Vaccinium …
Comparitive Study On Antioxidant Properties Of Dendrobium Officinale (Tiepishihu), Wenjun Zhu
Comparitive Study On Antioxidant Properties Of Dendrobium Officinale (Tiepishihu), Wenjun Zhu
Wayne State University Theses
For ages, Chinese herbs, such as Dendrobium Officinale (DO), have been used in Asian regions for treating various illnesses due to the high medicinal value. In this study, the DO plant Acetone and Ethanolic extracts possibly containing antioxidants were tested using different methodologies for comparison and determination of specific antioxidant capacity. The total phenolic content assay expressed as Gallic Acid Equivalent showed 9.43±;0.23 mg GAE /g of extract. Further analysis using DPPH· assay indicated that antioxidants presented in the sample were able to significantly scavenge 37% and 44% radicals at the concentrations of 25mg/ml and 50mg/mL respectively, after a period …
Effect Of Folate Deficiency On Mtor Signaling Network On The Liver Of Wild Type Mice, Essra Moussawi
Effect Of Folate Deficiency On Mtor Signaling Network On The Liver Of Wild Type Mice, Essra Moussawi
Wayne State University Theses
Through various studies of dietary nutrients on the affects of the physiological and molecular pathways are a key study in understanding the interaction between dietary nutrients and the human genome that may severely impact the development of various cancers. A primary approach is observing the dietary nutrients, that we consume and how it plays a role in the cellular pathway of our bodies through experimental methods. Folate deficiency (FD) has shown, through studies, to play a role anti-cancer progression. Our goal was to observe the autophagy related proteins in the mTOR signaling pathway as it was suggested that mTOR may …
Effect Of Long Term Rapamycin Treatment On Mtor Signalling Network In Colon And Liver Of C57bl/6 Mice, John Sorge
Effect Of Long Term Rapamycin Treatment On Mtor Signalling Network In Colon And Liver Of C57bl/6 Mice, John Sorge
Wayne State University Theses
Many studies have investigated the effects of rapamycin on aging and cancer. However, the effects of long-term rapamycin supplementation on a cancer model have not been performed. This is the first study that investigates the effects of long-term supplementation of rapamycin in a cancer model. ACF analysis of colon tissues in mice showed no significant difference between controls and those supplemented with rapamycin. Factors such as energy balance, cellular environment, PI3K/Akt/mTOR pathway, and more have been assessed in this study. The duration of rapamycin supplementation seems to play an important role in the protection against cancer. Ultimately, this study suggests …
Effect Of Folate Deficiency On Expression Of Proteins On The Mtor Signaling Pathway In The Brain Of C57/Bl6 Mice, Nikita Patel
Effect Of Folate Deficiency On Expression Of Proteins On The Mtor Signaling Pathway In The Brain Of C57/Bl6 Mice, Nikita Patel
Wayne State University Theses
ABSTRACT
EFFECT OF FOLATE DEFICIENCY ON EXPRESSION OF PROTEINS ON THE mTOR SIGNALING PATHWAY IN THE BRAIN OF C57/BL6 MICE
by
NIKITA PATEL
December 2014
Advisor: Dr. Ahmad Heydari
Major: Nutrition and Food Science
Degree: Master of Science
Nutrient-gene interactions can significantly impact several cellular processes in the human body by altering important molecular pathways. Nutrition can affect brain structure, function and development throughout the life cycle; it can have a profound effect on cognition ad mental health leading to neurodegenerative diseases. It is important to elucidate the mechanisms by which diet can effect signaling pathways in the brain. The …
Peri-Exercise Co-Ingestion Of Branched-Chain Amino Acids And Carbohydrate In Men Does Not Preferentially Augment Resistance Exercise-Induced Increases In Pi3k/Akt-Mtor Pathway Markers Indicative Of Muscle Protein Synthesis, Maria Pontes Ferreira, Rui Li, Matthew Cooke, Richard B. Kreider, Darryn S. Willoughby
Peri-Exercise Co-Ingestion Of Branched-Chain Amino Acids And Carbohydrate In Men Does Not Preferentially Augment Resistance Exercise-Induced Increases In Pi3k/Akt-Mtor Pathway Markers Indicative Of Muscle Protein Synthesis, Maria Pontes Ferreira, Rui Li, Matthew Cooke, Richard B. Kreider, Darryn S. Willoughby
Nutrition and Food Science Faculty Research Publications
The effects of a single bout of resistance exercise (RE) in conjunction with peri-exercise branched chain amino acid (BCAA) and carbohydrate (CHO) ingestion on skeletal muscle signaling markers indicative of muscle protein synthesis (MPS) were determined. It was hypothesized that CHO + BCAA would elicit a more profound effect on these signaling markers compared to CHO. Twenty-seven males were randomly assigned to CHO, CHO + BCAA, or placebo (PLC) groups. Four sets of leg presses and leg extensions were performed at 80% 1RM. Supplements were ingested 30 min and immediately prior to and after RE. Venous blood and muscle biopsy …
Contents, Discovery Editors
Contents, Discovery Editors
Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences
No abstract provided.
Eating Disorders: The Hidden Hormonal Effect On Fertility, Esther Tessler-Karfunkel
Eating Disorders: The Hidden Hormonal Effect On Fertility, Esther Tessler-Karfunkel
The Science Journal of the Lander College of Arts and Sciences
Women who have a history of eating disorders, specifically anorexia nervosa, are more prone to suffer from infertility. There are several hormones which are the driving force in this system and are therefore responsible for this. Fortunately, there are treatments which can help women with a history of eating disorders to reproduce. Using information found on Pubmed and Touro College’s database, this paper will discuss why the body cannot reproduce when it is lacking proper nutrition, as well as the various dynamics in the human reproductive system which are compromised when the body is not properly nourished.
Is Marital Status A Determinant Of Self-Monitoring Of Blood Glucose?, Jasmine Evelyn Dixon Jones
Is Marital Status A Determinant Of Self-Monitoring Of Blood Glucose?, Jasmine Evelyn Dixon Jones
Electronic Theses and Dissertations
Glycemic control is one of the most important aspects of diabetes management and is necessary for the prevention or delay of complications associated with diabetes mellitus (DM). Self-monitoring of blood glucose (SMBG) is a technique used achieve glycemic control by revealing day-to-day changes in blood glucose levels. Since marriage protective effects have been shown for mortality, especially for men, it is useful to determine whether a similar relationship is found between marriage and SMBG. The purpose of this study is to examine whether marital status is a determinant of SMBG, when controlling for other variables, and whether marital status determines …
Evaluating Dietary Amino Acid Adequacy In Horses Using Isotopic Techniques, Sara L. Tanner
Evaluating Dietary Amino Acid Adequacy In Horses Using Isotopic Techniques, Sara L. Tanner
Theses and Dissertations--Animal and Food Sciences
Little is known about amino acid (AA) requirements in horses despite muscle mass accretion being of importance to an athletic species. Isotope methods for determining AA requirements and whole-body protein synthesis (WBPS) had not been previously used in growing horses. The first study herein was the first to apply isotope methods to determine WBPS in growing horses. In the study, weanling colts received two different levels of crude protein. Whole-body protein kinetics indicated that WBPS was greater when the weanlings were fed the diet with a greater crude protein content (P<0.05). The second study sought to determine a lysine requirement for yearling horses using the indicator AA oxidation (IAAO) method. Despite using six dietary levels of lysine; three above and three below the current recommendation, no breakpoint could be determined. Phenylalanine kinetics were not affected by lysine level (P>0.05), but plasma lysine increased linearly with lysine intake …0.05).>
Effectiveness Of A Farm Field Trip, Bonnie S. Sigmon
Effectiveness Of A Farm Field Trip, Bonnie S. Sigmon
Theses and Dissertations--Community & Leadership Development
The annual Sigmon Farm Tour was started in 1992 as an agricultural education program where students could experience being on a farm with the goal of increasing the agricultural literacy levels of the participants. Every year the entire 4th grade student population of Rockcastle County spends the day touring the farm and participating in experiential mini lessons given by the cooperating farm service and health agencies. The program has continued for 20+ years without an evaluation as to whether it is achieving its objectives. This evaluation will also exhibit the programs strengths and weakness so it can continue to improve. …
Exploring The Relationship Between Emotional Brain Training, Stress, Depression, Food Addiction, And Weight, Bailey Regina Adams
Exploring The Relationship Between Emotional Brain Training, Stress, Depression, Food Addiction, And Weight, Bailey Regina Adams
Theses and Dissertations--Nutrition and Food Systems
Obesity is a complex issue; stress, depression, and food addiction, are several psychological conditions that can accompany an obesity diagnosis. Emotional Brain Training (EBT) was evaluated as a new approach to these conditions. Stress, depression, food addiction, and weight were assessed at baseline, after a seven week active intervention, and after a seven week no contact period. The final sample consisted of 26 obese adults. At seven week assessments, EBT participants experienced significant weight loss (p-value = 0.05) and decreased perceived stress (p-value = 0.035). Food addiction also decreased from 50% to 8.3% (or one participant). At fourteen week assessments, …
The Benefits Of Breastfeeding, Avery Kordus
The Benefits Of Breastfeeding, Avery Kordus
Senior Honors Theses
Breastfeeding research is plentiful, and the majority of the literature shows that breast milk is the superior form of infant nutrition except in the rare circumstances of infant metabolic disorders, maternal drug use, or positive HIV status. In comparison to formula, breast milk provides improved cognition, development, behavior, bonding, nutrition, digestion, immunity, and long-term health with fewer diseases and conditions in infants. Mothers are benefited by breastfeeding through bonding, faster weight loss, and reduction in certain cancers and conditions. Breast milk contains the proper amount of carbohydrates, fats, proteins, vitamins, and minerals, and is also specialized for each infant and …
The Theological And Practical Significance Of Health Reform In The Writings Of Ellen G. White, Angel Manuel Rodriguez
The Theological And Practical Significance Of Health Reform In The Writings Of Ellen G. White, Angel Manuel Rodriguez
Journal of the Adventist Theological Society
No abstract provided.
Essential Roots: Planting Seeds For A Bright Future; A Pilot Implementation Of Transitional Service That Promotes Nutritional Health And Business Skills For Students With Idd, Jennybeth S. Hendrick
Essential Roots: Planting Seeds For A Bright Future; A Pilot Implementation Of Transitional Service That Promotes Nutritional Health And Business Skills For Students With Idd, Jennybeth S. Hendrick
Honors Theses
Too many men and women with intellectual and/or developmental disabilities (IDD) are unable to live autonomously due to economic instability and the lack of knowledge to successfully make appropriate and healthy life choices. To improve attainment of financial independence and autonomous living, transitional services must be implemented into grade schools so that adolescents can master basic life skills to help their future quality of life. Essential Roots: Planting Seeds for a Bright Future, a pilot transitional program and evaluation was conducted in a classroom at the Scott Child Development Center, Oxford, MS. The goal of the non-randomized, controlled research study …
Obesity-Related Hormones And Metabolic Risk Factors: A Randomized Trial Of Diet Plus Either Strength Or Aerobic Training Versus Diet Alone In Overweight Participants, Allan Geliebter, Christopher N. Ochner, Carl L. Dambkowski, Sami A. Hashim
Obesity-Related Hormones And Metabolic Risk Factors: A Randomized Trial Of Diet Plus Either Strength Or Aerobic Training Versus Diet Alone In Overweight Participants, Allan Geliebter, Christopher N. Ochner, Carl L. Dambkowski, Sami A. Hashim
Lander College of Arts and Sciences Publications and Research
There is debate about the additive effects of exercise in conjunction with diet to treat obesity, and not much is known about the differential effects of strength versus aerobic training. This randomized controlled trial examined the effects of diet plus strength training, diet plus aerobic training, or diet only on metabolic risk factors associated with obesity. Eighty-one overweight and obese participants completed the 8-week intervention. All participants received an energy-restrictive formula diet with an energy content based on 70% of measured resting metabolic rate (RMR). Participants assigned to an exercise group trained 3 days/week under supervision. Anthropometrics and fasting hormones …
Skipping Breakfast Leads To Weight Loss But Also Elevated Cholesterol Compared With Consuming Daily Breakfasts Of Oat Porridge Or Frosted Cornflakes In Overweight Individuals: A Randomised Controlled Trial, Allan Geliebter, Nerys M. Astbury, Roni Aviram-Friedman, Eric Yahav, Sami Hashim
Skipping Breakfast Leads To Weight Loss But Also Elevated Cholesterol Compared With Consuming Daily Breakfasts Of Oat Porridge Or Frosted Cornflakes In Overweight Individuals: A Randomised Controlled Trial, Allan Geliebter, Nerys M. Astbury, Roni Aviram-Friedman, Eric Yahav, Sami Hashim
Lander College of Arts and Sciences Publications and Research
Eating breakfast may reduce appetite, body weight and CVD risk factors, but the breakfast type that produces the greatest health benefits remains unclear. We compared the effects of consuming a high-fibre breakfast, a non-fibre breakfast, or no-breakfast control on body weight, CVD risk factors and appetite. A total of thirty-six overweight participants (eighteen men and eighteen women) (mean age 33·9 (SD 7·5) years, mean BMI 32·8 (SD 4·7) kg/m2) were randomly assigned to consume oat porridge (n = 12), frosted cornflakes (n = 12) or a water control (n = 12) breakfast daily for 4 weeks. Appetite ratings were collected …
Parent's Use And Likely Use Of Nutrition Education Resources In The Mississippi Delta Region, Rachel Jessica Scoggins
Parent's Use And Likely Use Of Nutrition Education Resources In The Mississippi Delta Region, Rachel Jessica Scoggins
Electronic Theses and Dissertations
Objective: To identify nutrition education resources currently being used and those likely to be used if made available by parents of elementary-aged children in the Mississippi Delta region. Methods: Surveys were completed by 214 parents (92% female, 88% African American) of children in grades K-2nd from three schools in the Mississippi Delta region. Survey items obtained nutrition education resources currently used by parents , those likely to be used if made available, mode of delivery and mediators (individuals) providing nutrition education. Results: Parents reported high importance that their child eats healthy. Physicians were identified as the primary mediator for delivering …
The Reliability Of An Adolescent Dietary Pattern Identified Using Reduced-Rank Regression: Comparison Of A Ffq And 3 D Food Record, Geeta Appannah, Gerda K. Pot, Therese A. O'Sullivan, Wendy H. Oddy, Susan A. Jebb, Gina L. Ambrosini
The Reliability Of An Adolescent Dietary Pattern Identified Using Reduced-Rank Regression: Comparison Of A Ffq And 3 D Food Record, Geeta Appannah, Gerda K. Pot, Therese A. O'Sullivan, Wendy H. Oddy, Susan A. Jebb, Gina L. Ambrosini
Research outputs 2014 to 2021
Despite the increasing use of dietary patterns (DP) to study diet and health outcomes, relatively few studies have examined the reliability of DP using different dietary assessment methods. Reduced-rank regression (RRR) is an emerging statistical method that incorporates a priori information to characterise DP related to specific outcomes of interest. The aim of the present study was to compare DP identified using the RRR method in a FFQ with those in a 3 d food record (FR). Participants were 783 adolescents from the Western Australian Pregnancy (Raine) Cohort Study who completed both a FFQ and FR at 14 years of …
Misunderstanding The Female Athlete Triad: Refuting The Ioc Consensus Statement On Relative Energy Deficiency In Sport (Red-S), Mary Jane De Souza, Nancy I. Williams, Aurelia Nattiv, Elizabeth Joy, Madhusmita Misra, Anne B. Loucks, Gordon Matheson, Marion P. Olmsted, Michelle Barrack, Rebecca J. Mallinson, Jenna C. Gibbs, Marci Goolsby, Jeanne F. Nichols, Barbara Drinkwater, Charlotte (Barney) Sanborn, Rosemary Agostini, Carol L. Otis, Mimi D. Johnson, Anne Zeni Hoch, Julia M. K. Alleyne, L. Tyler Wadsworth, Karsten Koehler, Jaci Vanheest, Paula Harvey, Amanda K. Weiss Kelly, Michael Fredericson, George A. Brooks, Emma O'Donnell, Lisa R. Callahan, Margot Putukian, Lauren Costello, Suzanne Hecht, Mitchell J. Rauh, Jacalyn Mccomb
Misunderstanding The Female Athlete Triad: Refuting The Ioc Consensus Statement On Relative Energy Deficiency In Sport (Red-S), Mary Jane De Souza, Nancy I. Williams, Aurelia Nattiv, Elizabeth Joy, Madhusmita Misra, Anne B. Loucks, Gordon Matheson, Marion P. Olmsted, Michelle Barrack, Rebecca J. Mallinson, Jenna C. Gibbs, Marci Goolsby, Jeanne F. Nichols, Barbara Drinkwater, Charlotte (Barney) Sanborn, Rosemary Agostini, Carol L. Otis, Mimi D. Johnson, Anne Zeni Hoch, Julia M. K. Alleyne, L. Tyler Wadsworth, Karsten Koehler, Jaci Vanheest, Paula Harvey, Amanda K. Weiss Kelly, Michael Fredericson, George A. Brooks, Emma O'Donnell, Lisa R. Callahan, Margot Putukian, Lauren Costello, Suzanne Hecht, Mitchell J. Rauh, Jacalyn Mccomb
Department of Nutrition and Health Sciences: Faculty Publications
We are concerned that readers of the IOC paper will be confused and misled by the poorly referenced statements and frank (and sometimes dangerous) errors in the paper. The IOC authors should publish a correction of these and other errors noted. Broadening research of low energy availability in other groups, such as the male athlete, athletes of diverse ethnicities and the disabled athlete may help to advance science and may one day warrant introduction of a specific term for whatever serious clinical sequelae of energy deficiency may be discovered in future research on men.
Research on the “Female Athlete Triad” …
Discovery: The Student Journal Of Dale Bumpers College Of Agricultural, Food And Life Sciences - Volume 15 2014, Several Authors
Discovery: The Student Journal Of Dale Bumpers College Of Agricultural, Food And Life Sciences - Volume 15 2014, Several Authors
Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences
No abstract provided.
Addressing Public Health Risks Of Persistent Pollutants Through Nutritional Modulation And Biomimetic Nanocomposite Remediation Platforms, Bradley J. Newsome
Addressing Public Health Risks Of Persistent Pollutants Through Nutritional Modulation And Biomimetic Nanocomposite Remediation Platforms, Bradley J. Newsome
Theses and Dissertations--Chemistry
Due to their relative chemical stability and ubiquity in the environment, chlorinated organic contaminants such as polychlorinated biphenyls (PCBs) pose significant health risks and enduring remediation challenges. Engineered nanoparticles (NPs) provide a novel platform for sensing/remediation of these toxicants, in addition to the growing use of NPs in many industrial and biomedical applications, but there remains concern for their potential long-term health effects. Research highlighted herein also represents a transdisciplinary approach to address human health challenges associated with exposure to PCBs and NPs. The objectives of this dissertation research are two-fold, 1) to develop effective methods for capture/sensing and remediation …
High Fat Diet Increased Serum Glutamate Dehydrogenase More Than Chronic Acetaminophen Dosing In Female Mice, Elizabeth Ruth Behmer
High Fat Diet Increased Serum Glutamate Dehydrogenase More Than Chronic Acetaminophen Dosing In Female Mice, Elizabeth Ruth Behmer
All Graduate Theses, Dissertations, and Other Capstone Projects
This laboratory study examined the effects of acetaminophen overdose in normal fed and high-fat fed female mice. Forty female mice were placed on normal and high-fat diets at 4 weeks old. When the mice were significantly different in weight (between 6 and 9 months old), half the mice were dosed with acetaminophen. These mice were daily given an overdose of acetaminophen for 14 days. The dose used was 300 mg/kg mouse (LD50 = 338 mg/kg). The control group was given 10 µl water/g mouse. Levels of serum glutamate dehydrogenase (GDH) were measured to indicate liver damage. GDH is released from …
Effects Of Globalization On The Use Of The Mediterranean Diet In Spain, Jacob J. Mcgee
Effects Of Globalization On The Use Of The Mediterranean Diet In Spain, Jacob J. Mcgee
Honors Theses
Spain is known for its sandy beaches, vibrant nightlife, and incredible foods. The Mediterranean diet of Spain is praised for its health benefits, but recently it appears that the population has begun to turn away from their original diet. Studies have shown that the Spanish have been experiencing a constant culture change due to globalization since the 1950s when the General Francisco Franco allowed the technocrats to have some control over the government. With a new economic policy, new people and their new ideas flooded the country bring with them their cultures. These cultures influenced the Spanish life changing many …
Parenteral Nutrition Web-Based Order Writing: Educating Prescribers Utilizing A Network-Wide Computerized E-Learning Tool, Judy Holaska Rd, Ms, Cnsc , Ldn
Parenteral Nutrition Web-Based Order Writing: Educating Prescribers Utilizing A Network-Wide Computerized E-Learning Tool, Judy Holaska Rd, Ms, Cnsc , Ldn
Clinical Nutrition Service
No abstract provided.
Do Flame Retardants Promote Vitamin D Deficiency?, Audrey Petteruti
Do Flame Retardants Promote Vitamin D Deficiency?, Audrey Petteruti
Honors Theses and Capstones
Vitamin D deficiency in the Unites States has become more prevalent in recent years. Research has shown that environmental chemicals such as flame-retardants induce hepatic enzymes in the cytochrome P450 family such as CYP24 and CYP3A that are important in vitamin D metabolism. To determine if exposure to one class of flame-retardants known as polybrominated diethyl ethers (PBDEs) promotes vitamin D deficiency, 15 rats consumed a diet marginally deficient in Vitamin D - 85 IU Vitamin D/kg diet - for 56 days. On day 28 of the experiment, 7 rats were gavaged daily with 7 mg/kg BW PBDEs and 8 …
Impact Of Nutrition On Cognition And Its Association With Blood And Brain Alzheimer Disease Related Biomarkers, Samantha Gardener
Impact Of Nutrition On Cognition And Its Association With Blood And Brain Alzheimer Disease Related Biomarkers, Samantha Gardener
Theses: Doctorates and Masters
Alzheimer’s disease (AD), the most common form of senile dementia, currently affects over 35 million people worldwide. While there is no cure or effective treatment, early intervention programs hold considerable promise. Following particular dietary patterns represents one potential intervention strategy accessible to all.
Results from previous studies investigating the association of diet, cognition and biomarkers of AD are inconsistent: Positive results have been reported (1-7), whilst others have shown no associations. Prior to this thesis, no study has assessed the relationship of four dietary patterns to cognition, blood-based and neuroimaging biomarkers of AD in a large highly-characterised ageing cohort. Participants …
Isolation And Characterization Of Natural Alpha-Glucosidase Inhibitors From Antioxidant Rich Red Wine Grapes (Vitis Vinifera), Hoda Chaouki Kadouh
Isolation And Characterization Of Natural Alpha-Glucosidase Inhibitors From Antioxidant Rich Red Wine Grapes (Vitis Vinifera), Hoda Chaouki Kadouh
Wayne State University Dissertations
Background: Diabetes is currently a global public health problem affecting people at all ages. Dietary antioxidants have been associated with a reduced risk of type 2 diabetes. Grape pomace contains considerable amounts of polyphenols and it has been reported to exhibit an inhibitory activity against alpha- glucosidases. Alpha-glucosidases, in turn, play a major role in controlling starch digestion and therefore postprandial blood glucose, a target for diabetes management.
Objective: This study aims to investigate the anti-diabetes potential of a selection of six grape pomaces and prepare and purify active components in the active variety that specifically inhibit intestinal alpha-glucosidases. The …