Nutrition Commons^™

The Effects Of Acute Post Exercise Consumption Of Two Cocoa-Based Beverages With Varying Flavanol Content On Indices Of Muscle Recovery Following Downhill Treadmill Running, Katelyn Peschek, Robert Pritchett, Ethan Bergman, Kelly Pritchett

All Faculty Scholarship for the College of the Sciences

Dietary flavanols have been associated with reduced oxidative stress, however their efficacy in promoting recovery after exercise induced muscle damage is unclear. This study examined the effectiveness of acute consumption of cocoa-flavanols on indices of muscle recovery including: subsequent exercise performance, creatine kinase, muscle tenderness, force, and self-perceived muscle soreness. Eight endurance-trained athletes (VO2max 64.4 ± 7.6 mL/kg/min) completed a downhill running protocol to induce muscle soreness, and 48-h later completed a 5-K (kilometer) time trial. Muscle recovery measurements were taken at PRE, 24 h-POST, 48 h-POST, and POST-5K. Participants consumed 1.0 g of carbohydrate per kilogram of body weight …

Studies On The Regulation Of Fgf21 Gene Expression By (R)-Α-Lipoic Acid: Mechanistic Insight Into The Lipid Lowering Properties Of A Dithiol Dietary Molecule, Xiaohua Yi

Department of Nutrition and Health Sciences: Dissertations, Theses, and Student Research

Controlling blood lipids is a major public health challenge of our time. The pleiotropic hormone-like polypeptide fibroblast growth factor 21 (FGF21) was recently recognized as a potent modulator of lipid and glucose metabolism and a promising treatment strategy for obesity related metabolic disorders, including dyslipidemia. A cost effective and practical alternative to the administration of recombinant FGF21 is to stimulate endogenous FGF21 production through diet. Our research identified (R)-a-lipoic acid (LA), a naturally occurring enzyme cofactor and dietary molecule found in green leafy vegetable and red meat, as an inducer of FGF21 expression. LA stimulated FGF21 production, demonstrated by a …

Biotinylation Of The C-Myc Promoter Binding Protein Mbp-1 Decreases C-Myc And Cox-2 Expression In Mammary Carcinoma Mcf-7 Cells, Jie Zhou

Department of Nutrition and Health Sciences: Dissertations, Theses, and Student Research

Biotin feeding in a Balb/c mouse model of breast cancer suggest that the tumor load is ~100% greater in biotin-deficient mice compared with biotin-sufficient controls, and that the increase is associated with metastasis rather than new tumors. The oncogenes c-Myc and COX-2 are implicated in cancer metastasis, and their expressions are repressed by binding of MBP-1 to the promoter. Mass spectrometry studies, designed to discover novel biotin-containing proteins, suggest that lysine residues K10 and K12 in the c-Myc promoter binding protein (MBP-1) contains covalently bound biotin (MBP-1bio). We hypothesized that biotinylation of MBP-1 increases the binding of MBP-1 to the …

The Cost Of Affordable Food, Candice L. Cobuzzi

SURGE

When someone puts a piece of food in front of me, I don’t just see a piece of food.

Instead, I see an innocent cow being cornered by a forklift and slaughtered, its limp, moist tissue hung on a long conveyer belt with hundreds of others.

I see hundreds of chemically-injected chickens packed into a dark barn with no hope of seeing sunlight in their lifetime.

I see immigrants pulled from their houses like criminals, taken away from the lives they’ve spent years building for themselves and their families, working for the same food company that courted them into the …

Anti-Cancer Effects Of Garcinol In Pancreatic Cancer Transgenic Mouse Model, Nadia Saadat

Wayne State University Dissertations

Adenocarcinoma of pancreas is recognized for its poor prognosis, as it progresses asymptomatically and is rarely diagnosed at early stage. According to American cancer society pancreatic cancer, it has lowest survival rate in all cancer types, with less than 6% five year survival rate. Surgical resection is only possible for 20% of diagnosed cases and current chemotherapy has only 15% response rate. Even the most favored drug, Gemcitabine, increases survival time only by a few months, depending on the stage at diagnosis. Some bioactive food components or nutraceuticals have shown chemopreventive and chemotherapeutic effects without added side effects. Garcinol is …

Three Essays Evaluating Health Impacts Of The National School Lunch Program, Janet Peckham

All Dissertations

This research focuses on the health impacts of participation in the National School Lunch Program, a program providing free and reduced-cost lunches for income-eligible students and minimally subsidizing lunches for income-ineligible students. In the past decade, increasing incidence of childhood obesity, particularly among low-income individuals has drawn scrutiny over the NSLP's role in the health of student-aged children.

The first chapter introduces the reader to the NSLP, providing a history of the program since its inception at the turn of the 20th century and addressing current issues in the economic literature regarding health impacts of program participation. The second chapter …

Utah Red Raspberry Jam: The Effects Of Formulation, Heating, And Time On Color, Flavor, Texture, And Antioxidant Capacity, Jennifer Leigh Chase

Theses and Dissertations

The amount and type of antioxidants present in raspberries is dependent upon cultivar, ripeness, and growing conditions. Previous research on raspberry jam has reported some color, antioxidant, and flavor loss after processing and storage, though it is unknown to what extent similar changes will occur in raspberries grown in Utah. Sugar concentration and heating temperature as well as storage time were evaluated in an effort to maximize color retention, flavor, antioxidant content, shelf life, and consumer acceptance of Utah-grown raspberry jam. Four types of jams were processed in two batches each: low-sugar (40-42 Brix) and typical sugar (65-68 Brix) at …

Strategies For Success, Winston J. Craig

Lake Union Herald

No abstract provided.

Bridging Patient Outcome Gap For Type 2 Diabetes : Can We Bridge Physician Practices To Produce Results Achieved In Evidence-Based Lifestyle Intervention Research?, Brenda Killen Johnson

Theses, Dissertations and Culminating Projects

The United States is abounding in the prevalence and incidence of avoidable chronic diseases, and high among these diseases is type 2 diabetes. Further, according to the National Institute of Health (NIH) Common Fund, 40% of harmful health behaviors is what contributes to chronic diseases, such as type 2 diabetes. NIH noted there are few personalized, effective ways to inspire people to change their behaviors in the shortterm, but if done, this behavior is not sustained long-term (The NIH Common Fund, 2011). Yet, this research discovered a Diabetes Prevention Program (DPP) is one of these few personalized, effective interventions that …

Effect Of Functional Starch In Brown Rice And Grain Sorghum On Plasma Glucose And Insulin Responses In Humans, Nicole Marie Poquette

Graduate Theses and Dissertations

Diabetes and obesity are chronic illnesses increasing at dramatic rates in the U.S. and around the world. Research has looked to prevent or control diabetes and obesity through functional ingredients such as healthy-dietary carbohydrates to control blood glucose levels. Starch is a principle carbohydrate, which influences blood glucose levels, and measuring starch digestibility fractions can help predict the glucose response in the body. The objectives of this study were to investigate the functional starch content of parboiled brown rice flour and grain sorghum flour, and measure the effects on postprandial plasma glucose and insulin levels of 14 and 10 healthy …

Development Of Food Safety Education And Pilot Study Specifically For Native Americans Audiences, Kristine M. Foley

Department of Nutrition and Health Sciences: Dissertations, Theses, and Student Research

The purpose of this study was to develop and implement a culturally appropriate food safety educational program using the conceptual change teaching method while preparing a meal. The food safety educational program was based on the FightBac!™ concepts (CLEAN, SEPARATE, COOK AND CHILL). Quantitative and qualitative date were collected, compared, and analyzed. Two pilot studies were conducted with Native American participants on non-reservation sites in Omaha and Lincoln. A total of 27 participants completed a pre and post knowledge survey and were video recorded preparing a meal. The majority of the participants were female (78%), had at least a high …

Reading And Listening To Music Increase Resting Energy Expenditure During Indirect Calorimetry In Healthy Adults , Blaire Snell

Theses and Dissertations

The Academy of Nutrition and Dietetics has developed an evidence analysis library (EAL) for Nutrition and Dietetics professionals. The EAL is updated by members through workgroups consisting of experts in their fields, most often in response to unanswered questions. One such question is: what kinds of activities can be done during the rest period of an indirect calorimetry test in a healthy population? The objective of our study was to determine if listening to self-selected relaxing music or reading on an electronic device or a magazine effects resting energy expenditure (REE) as measured by an indirect calorimetry test in a …

Vitamin D Status And Bone Mineral Density In Triathletes, Michelle Konstantarakis

UNLV Theses, Dissertations, Professional Papers, and Capstones

Purpose: The purposes of this study were first to assess the vitamin D status and bone mineral density (BMD) in male and triathletes (N=15), female triathletes (N=13), and non-athletes (N=14), and to determine if circulating vitamin D was correlated with body composition, BMD, dietary calcium and vitamin D intake in triathletes. The second purpose was to determine if triathletes have a different level of serum vitamin D, body composition, BMD, dietary calcium and vitamin D intake then non-athletes. The third purpose was to determine if BMD was correlated with body composition (body mass, percent body fat, BMI) in triathletes.

Methods: …

Evaluation Of The Relationship Between Nutrition Knowledge And Disordered Eating Risk In Female Collegiate Athletes, Amy L. Miracle

UNLV Theses, Dissertations, Professional Papers, and Capstones

Involvement in collegiate sports among female athletes is at an all-time high with approximately 198,000 currently participating, (National Collegiate Athletic Association, 2012). With this increase in female participation in collegiate sports, the pressures of sport participation and academics lead some women to engage in harmful eating behaviors. These harmful eating behaviors may lead to the development of disordered eating (C. Johnson, Powers, & Dick, 1999; Quatromoni, 2008; Reel, SooHoo, Petrie, Greenleaf, & Carter, 2010; Reinking & Alexander, 2005). Many factors have been identified as contributing to the development of disordered eating but nutrition knowledge or lack thereof, has yet to …

Vitamin And Mineral Intake Relative To The Dris In Young Adults, Samantha M. Coogan

UNLV Theses, Dissertations, Professional Papers, and Capstones

INTRODUCTION: In general, most college-aged students live highly, and newly, independent lives. Although campuses offer wide varieties of food choices, most choices do not meet the standards set by the RDA or DRIs, per NHANES 1999-2000.

METHODS: In order to document these eating patterns, 1001 male (n=379) and female (n=622) college-aged students quantified dietary intake for three consecutive days using the food log method. Assessment reports were generated and analyzed in order to determine the percentage of the DRI in both males and females, and groups with a BMI of less than 20 and greater than 30. Tests for correlation …

In Vitro Analysis Of Short Chain Fatty Acids And Human Fecal Microbiota Stimulated By Pectin Sources, Byungjick Min

Graduate Theses and Dissertations

As interest increases for colonic health, various studies have been conducted to investigate functional ingredients for host health and prevention of chronic disease in humans such as colon cancer and Type 2 diabetes. In particular dietary fiber has been reported to have beneficial effects on colonic health. More recently, dietary fiber has been categorized based on its characteristics and numerous studies have been conducted to determine correlations with chronic diseases. Pectin is a naturally occurring biopolymer that has been used in various applications for purposes of pharmaceutical and biotechnology. Pectin is a soluble dietary fiber and can be entirely fermented …

Table For One, Food For Two: A Socio-Economic Perspective On American Obesity, Celestina Victoria Brunetti

Honors Theses - Providence Campus

Research indicates that obesity is linked to socio-economic factors and genetics. Both have an impact on whether a person is or becomes obese. The paper focuses on the impact of the change in food supply along with socio-economic factors, specifically access, time, and cost, and how these factors have affected the American obesity epidemic. This was assessed in part through a case study of the Smith Hill area of Providence, Rhode Island, a food desert that is comprised mainly of Americans near the poverty line, and the Wellspring La Jolla camp—a camp for overweight children from upper-middle class families. The …

Enhanced Water, Winston J. Craig

Lake Union Herald

No abstract provided.

Lifestyle, Dietary Factors, And Antibody Levels To Oral Bacteria In Cancer-Free Participants Of A European Cohort Study, Dominique S. Michaud, Jacques Izard, Zachary Rubin, Ingegerd Johansson, Elisabete Weiderpass, Anne Tjønneland, Anja Olsen, Kim Overvad, Marie Christine Boutron-Ruault, Françoise Clavel-Chapelon, Laure Dossus, Rudolf Kaaks, Verena A. Katzke, Heiner Boeing, Jana Foerster, Antonia Trichopoulou, Androniki Naska, Giana Ziara, Paolo Vineis, Sara Grioni, Domenico Palli, Rosario Tumino, Amalia Mattiello, Petra Hm Peeters, Peter D. Siersema, Aurelio Barricarte, José-María Huerta, Esther Molina-Montes, Miren Dorronsoro, J. Ramón Quirós, Eric J. Duell, Bodil Ohlsson, Bengt Jeppsson, Anders Johansson, Pernilla Lif, Kay-Tee Khaw, Nick Wareham, Ruth C. Travis, Tim J. Key, Heinz Freisling, Talita Duarte-Salles, Magdalena Stepien, Elio Riboli, H. Bas Bueno-De- Mesquita

Department of Food Science and Technology: Faculty Publications

Background: Increasing evidence suggests that oral microbiota play a pivotal role in chronic diseases, in addition to the well-established role in periodontal disease. Moreover, recent studies suggest that oral bacteria may also be involved in carcinogenesis; periodontal disease has been linked several cancers. In this study, we examined whether lifestyle factors have an impact on antibody levels to oral bacteria.

Methods: Data on demographic characteristics, lifestyle factors, and medical conditions were obtained at the time of blood sample collection. For the current analysis, we measured antibody levels to 25 oral bacteria in 395 cancer-free individuals using an immunoblot …

The Effects Of White Bass (Morone Chrysops) Predation On Juvenile June Suckers (Chasmistes Liorus), Michael J. Whitney, Dr. Mark C. Belk

Journal of Undergraduate Research

We estimated the vulnerability of juvenile June suckers to predation by a growing cohort of juvenile white bass. Also, habitat preference of juvenile white bass (open versus vegetated habitats) in the presence and absence of adult white bass was determined experimentally. Juvenile white bass preferred vegetated habitats similar to juvenile June suckers. June suckers are most vulnerable to juvenile white bass immediately after they hatch and move downstream into Utah Lake. Vulnerability decreases during the summer until by the end of the growing season. Only a small fraction of the juvenile June sucker population is potentially vulnerable to juvenile white …

Selenium Moderation Of Estrogen Receptor-Beta (Er-B) Activation: A Mechanism For Prostate Cancer Chemoprevention, Josie Johnson, Dr. Merrill J. Christensen

Journal of Undergraduate Research

Prostate cancer is the second leading cause of cancer death in men (1). Results from a prospective cancer prevention trial showed that Se supplementation reduced prostate cancer incidence by 63% (2). One molecular mechanism by which Se may protect against prostate cancer is moderation of the conformation and associated activity of redox-regulated proteins, including some transcription factors (3). Previous work in our laboratory showed that Se affects the expression of genes responsive to the redox-regulated transcription factor NF-kB in human prostate cancer (LNCaP) cells (4). Estrogen receptor-beta (ER-b) is another redox-regulated transcription factor. We report that Se treatment of LNCaP …

Anterior-Posterior Limb Position Is Dependent On The Relative Timing Of Key Embryonic Events, Tyler Prestwich, Dr. Michael Stark

Journal of Undergraduate Research

To better understand embryonic events leading to the determination of limb position along the anterior-posterior (A-P) axis, we compared pre-limb bud stage developmental morphology of three vertebrate organisms: chicken, goose and swan. These organisms were selected because of the differences each exhibit with regard to the A-P location of the forelimbs, or more specifically, the number of cervical vertebrae. By observing disparities between the embryonic morphologies of the different species, we were able to identify specific morphological distinctions that correlate with A-P patterning. Based on the data obtained, we hypothesize a mechanism whereby a delay in embryonic “differentiation” in relationship …

The Role Of Ap-1 And Related Inhibitors In Cortisol Secretion And Inflammation, D. Craig Seager, Dr. Allan Judd

Journal of Undergraduate Research

Interleukin-6 (IL-6) increases the secretion of cortisol from bovine adrenal zona fasciculata (ZF) and human adrenal tumor H295R cells. However, the biochemical mechanisms involved in IL- 6-stimulated cortisol secretion are not well understood. In previous studies, it has been determined that IL-6 increases the phosphorylation of Janus kinases (JAK) and signal transducer and activators of transcription (STATs). In many tissues, the JAK-STAT pathway and the activator protein-1 (AP-1) pathways interact. AP-1 is composed of homodimers and heterodimers of the proteins c-Fos, c-Jun, JunB, and JunD. Therefore, in this study we determined the effects of IL-6 on the cellular content of …

Long-Term Preservation Of Breadfruit, Cassava, And Taro By Solar-Drying In The Pacific Islands Area, Jonathan Pratt Rowe

Journal of Undergraduate Research

Cassava, taro, and breadfruit are critical food sources indigenous to the Pacific islands. Because they serve as the main source of energy for 500 million people, their availability is vital to the survival of these people. In addition to the energy provided, these plants also provide essential vitamins and minerals. Generally, cassava, taro, and breadfruit are grown with relative ease and abundance. Their physical and chemical properties, however, are not conducive to storage, and as a result, much is wasted.

Theory Of Planned Behavior To Predict Multivitamin/Mineral Use, Heather Petraszko

Master's Theses and Doctoral Dissertations

This health behavior research study utilizes the theory of planned behavior (TPB) to explore female collegiate lightweight rowers' (FCLR) decision to use multivitamin/mineral supplements (MVS). This study aimed to determine the relationship between FCLR salient beliefs, attitudes, subjective norms, and perceived behavior control (PBC) towards MVS, intention to use MVS, and use of MVS. Subjects were recruited from sixteen collegiate lightweight women's rowing programs within the United States and Canada and asked to complete an online survey. Results confirmed that the subjects' attitudes and PBC, but not subjective norms, were associated with intention to use MVS. In agreement with TPB …

A Comparison Of The Impact Of A Heart-Healthy Diet Versus Paleolithic Nutrition On Hyperlipidemia In Adults, Robert Pastore

Master's Theses and Doctoral Dissertations

Paleolithic nutrition can optimize serum lipids in adults with hyperlipidemia who have been on a heart-healthy diet based on the current recommendations by the Academy of Nutrition and Dietetics (the Academy) or the American Heart Association (AHA). Twenty subjects (10 male and 10 female) age 40 to 62 were selected based on the criteria of a diagnosis of hypercholesterolemia. Subjects were not taking any cholesterol lowering medication and had followed a calorie-controlled diet, based on either the dietary principles of the Academy or the AHA, for at least four months followed by a Paleolithic diet for four months. Multivariate analysis …

Supplement Shortfall, Winston J. Craig

Lake Union Herald

No abstract provided.

Natural Genetic Variation Affecting Calcium Homeostasis, Rebecca Anna Replogle

Open Access Dissertations

Calcium (Ca) is essential for multiple functions within the body including skeletal health. The level of Ca in the serum is tightly regulated. During periods of habitual low Ca intake, the body senses a decrease in serum Ca and increases renal conversion of 25 hydroxyvitamin D (25(OH)D) to 1,25 dihydroxyvitamin D (1,25(OH)2D). 1,25(OH)2D acts through the vitamin D receptor (VDR) to increase intestinal Ca absorption, renal Ca reabsorption and skeletal Ca resorption. Efficient intestinal Ca absorption, especially during periods of low Ca intake, is critical for protecting bone mass. Ca absorption and its primary regulator, 1,25(OH)2D, are affected by both …

Brain Bioavailability Of Polyphenols: Implications For Delivery Of Brain Health Benefits, Tzu-Ying Chen

Open Access Dissertations

Consumption of fruits and vegetables has been associated with neuroprotection and cognitive benefits throughout the life span. These associations have sparked interest in plant-derived polyphenols as biologically active agents with potential for targeting brain benefits. However, little is known regarding the ability of the polyphenols or their metabolites from polyphenol-rich products to cross the blood-brain-barrier, and be available for biological action. Furthermore, additional insight is needed on factors affecting the absorption and brain distribution of polyphenol metabolites in vivo. To fill gap in current knowledge, this thesis will focus on the effects of diabetogenic diet and diabetic state which have …

Metabolic Characterization Of A Sirt5 Deficient Mouse Model, Jiujiu Yu, Sushabhan Sadhukhan, Lilia G. Noriega, Norman Moullan, Bin He, Robert S. Weiss, Hening Lin, Kristina Schoonjans, Johan Auwerx

Department of Nutrition and Health Sciences: Faculty Publications

Sirt5, localized in the mitochondria, is a member of sirtuin family of NAD1-dependent deacetylases. Sirt5 was shown to deacetylate and activate carbamoyl phosphate synthase 1. Most recently, Sirt5 was reported to be the predominant protein desuccinylase and demalonylase in the mitochondria because the ablation of Sirt5 enhanced the global succinylation and malonylation of mitochondrial proteins, including many metabolic enzymes. In order to determine the physiological role of Sirt5 in metabolic homeostasis, we generated a germline Sirt5 deficient (Sirt52/2) mouse model and performed a thorough metabolic characterization of this mouse line. Although a global protein hypersuccinylation and elevated serum ammonia during …