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Full-Text Articles in Nutrition

Diet Quality As Assessed By The Healthy Eating Index-2020 Among Individuals Diagnosed With And Without Type 2 Diabetes, Minghao Zhou, Hairui Yu, Renee Underwood, Hongning Cai, Tung Sung Tseng, Susu Luo Dec 2026

Diet Quality As Assessed By The Healthy Eating Index-2020 Among Individuals Diagnosed With And Without Type 2 Diabetes, Minghao Zhou, Hairui Yu, Renee Underwood, Hongning Cai, Tung Sung Tseng, Susu Luo

School of Public Health Faculty Publications

Background: Dietary management is key to preventing and controlling type 2 diabetes mellitus (T2DM). However, few studies have examined differences in Healthy Eating Index (HEI-2020) scores and components among individuals with and without diagnosed T2DM. This study aimed to assess gender differences in HEI-2020 scores and its 13 components by T2DM status. Methods: Using National Health and Nutrition Examination Survey (NHANES) data from 2011 to 2018, this cross-sectional study analyzed 19,464 adults. Diagnosed T2DM was identified via self-report or diabetes medication use. Diet quality was assessed using the HEI-2020, scored from 0 to 100, with a higher HEI score indicates …


Malnutrition Risk, Nutrition Insecurity, Barriers, And Facilitators To Dietary Management Among Adults With Inflammatory Bowel Disease In The Us Rocky Mountain Region: A Cross-Sectional Mixed-Methods Study, Heather Burr, Carrie Durward, Korry Hintze, Getrude Mphwanthe Aug 2026

Malnutrition Risk, Nutrition Insecurity, Barriers, And Facilitators To Dietary Management Among Adults With Inflammatory Bowel Disease In The Us Rocky Mountain Region: A Cross-Sectional Mixed-Methods Study, Heather Burr, Carrie Durward, Korry Hintze, Getrude Mphwanthe

Nutrition, Dietetics, and Food Science Student Research

We conducted an online cross-sectional study to assess malnutrition risk, food and nutrition insecurity, and perceived barriers and facilitators to dietary management among adults (18–64 years old) with a self-reported clinical diagnosis of inflammatory bowel disease (IBD) in outpatient and community settings. We assessed malnutrition risk using the Saskatchewan IBD-Nutrition Risk screening tool, food security risk using the two-item Hunger Vital Signs questionnaire, and nutrition security risk using a validated four-item tool. Open-ended questions elucidated barriers and facilitators to dietary management of IBD. Among 57 participants who self-reported a clinical diagnosis of IBD, 52.6% (n = 30/57) had ulcerative colitis, …


Staphylococcus Aureus Urease Is Controlled By A Complex Regulatory Network To Promote Dissemination During Cauti, Jana Gomez, Jesus Duran-Ramirez, Maristhela Alvarez, Shane Cristy, Jennifer N Walker Aug 2026

Staphylococcus Aureus Urease Is Controlled By A Complex Regulatory Network To Promote Dissemination During Cauti, Jana Gomez, Jesus Duran-Ramirez, Maristhela Alvarez, Shane Cristy, Jennifer N Walker

Faculty, Staff and Student Publications

Catheter-associated urinary tract infections (CAUTIs) are one of the most common hospital-associated infections in the United States, accounting for >1 million cases annually. One CAUTI pathogen, Staphylococcus aureus, is commonly found persisting asymptomatically in the bladder of catheterized individuals, increasing these individuals' risk of developing infection. Importantly, S. aureus is not only associated with severe symptoms during CAUTI, including bacteremia and septic shock, but it also produces a common uropathogen-associated virulence factor, urease. Despite its importance, urease has only been well-studied in another uropathogen, Proteus mirabilis. While previous studies identified three S. aureus urease regulators, including CodY, …


Full-Fat Dairy Milk Vs. Isolated Free Nutrient Blend On Postprandial Protein Metabolism And Inflammatory Markers In Adults With Overweight And Obesity, Takeshi M. Barnes, Zan Zupancic, Max T. Deutz, Andrew T. Askow, Colleen F. Mckenna, Jonathan A. Aguilera, Cassidy T. Tinline-Goodfellow, Alexander V. Ulanov, Jared W. Willard, Daniel W. D. West, Michael De Lisio, Daniel R. Moore, Nicholas A. Burd Aug 2026

Full-Fat Dairy Milk Vs. Isolated Free Nutrient Blend On Postprandial Protein Metabolism And Inflammatory Markers In Adults With Overweight And Obesity, Takeshi M. Barnes, Zan Zupancic, Max T. Deutz, Andrew T. Askow, Colleen F. Mckenna, Jonathan A. Aguilera, Cassidy T. Tinline-Goodfellow, Alexander V. Ulanov, Jared W. Willard, Daniel W. D. West, Michael De Lisio, Daniel R. Moore, Nicholas A. Burd

Kinesiology & Sport Management Scholarship

Excess adiposity is linked to anabolic resistance by blunting the postprandial myofibrillar protein synthetic response to protein ingestion. Full-fat dairy milk may overcome this resistance via a matrix combining high-quality protein with anti-inflammatory lipids. Therefore, we compared the effects of ingesting full-fat dairy milk versus a non-dairy macronutrient match isolated blend on the regulation of postprandial myofibrillar and mitochondrial protein synthesis rates and markers of systemic (i.e., IL-6 and TNF-α) and muscle-related inflammation (i.e., NF-κB, NLRP3, TLR4, and MyD88). Twenty-two obese and overweight adult males and females (BMI = 31.1 ± 3.7 kg m−2; aged 35.3 ± 13.2 y) were …


Pre-Post Changes In Physiological, Cognitive, And Motivational Outcomes Following An Active Video Game Intervention In Adolescents And Adults: A Pilot Study, Ashley Williams, Danielle D. Wadsworth, Thaangiah Geetha Aug 2026

Pre-Post Changes In Physiological, Cognitive, And Motivational Outcomes Following An Active Video Game Intervention In Adolescents And Adults: A Pilot Study, Ashley Williams, Danielle D. Wadsworth, Thaangiah Geetha

Publications

Active video games (AVG) are emerging as a promising home-based strategy to increase physical activity by integrating movement into interactive gameplay. However, evidence remains limited regarding their effectiveness across physiological, cognitive, and motivational outcomes in adolescents and adults within household settings.


Comparison Of Methods For Defatted Human Milk And Nutrient Composition: An Experimental Study, Kristin Cheng, Gina O'Toole, Stephanie Chang, Richard Chang, John Miklavcic Jul 2026

Comparison Of Methods For Defatted Human Milk And Nutrient Composition: An Experimental Study, Kristin Cheng, Gina O'Toole, Stephanie Chang, Richard Chang, John Miklavcic

Food Science Faculty Articles and Research

Background

Human milk is considered the gold standard for infant nutrition; however, it is often discontinued in chylothorax and severe very long-chain acyl-CoA dehydrogenase (VLCAD) deficiency. As an alternative to complete human milk restriction, defatted human milk may be fed, though it may not fully support optimal infant growth and development. This study aimed to assess the micronutrient profile of defatted human milk.

Methods

Human milk was obtained from UCSD Human Milk Research Biorepository (San Diego, CA). Thirty samples representing 10 independent expressions in the morning, afternoon, and evening were pooled for analysis. Fat removal was performed by centrifugation at …


Evaluating Variety- And Market-Class-Specific Effects Of Dietary Pulses On Human Health, Jiayu Tang Jul 2026

Evaluating Variety- And Market-Class-Specific Effects Of Dietary Pulses On Human Health, Jiayu Tang

Department of Food Science and Technology: Dissertations, Theses, and Student Research

While pulses are globally recognized for their high levels of dietary fibers, protein, and polyphenols, research often focuses on characterizing the physiological effects of a single variety. This approach overlooks the substantial genetic and compositional diversity that exists across pulse varieties and individual market classes, which can differ extensively in nutrient content and structure. These compositional differences have the potential to produce distinct physiological and microbial responses in humans, yet variety- and market-class-specific effects remain poorly characterized.

This thesis uses two complementary research methodologies to investigate the health-relevant effects of different pulse varieties and market classes, providing foundational knowledge to …


Limitations And Alternative Applications Of Carbohydrate Fatty Acid Esters As Food Antimicrobials: A Review, Valeria Rodríguez Monge, Namhyeon Park Jun 2026

Limitations And Alternative Applications Of Carbohydrate Fatty Acid Esters As Food Antimicrobials: A Review, Valeria Rodríguez Monge, Namhyeon Park

Nutrition, Dietetics, and Food Science Student Research

Carbohydrate fatty acid esters (CFAs) are nontoxic food additives with reported antimicrobial activity and growing interest as a potential safer alternative to conventional preservatives. However, their translation into real food systems remains limited. This review examined the main factors that restrict the antimicrobial performance of CFAs in foods and evaluated emerging alternative applications, particularly edible coatings, antibiofilm strategies, and synergistic combinations with other cleaning agents or processing techniques. Overall, the available evidence indicates that the antimicrobial efficacy of CFAs is often reduced in real food matrices compared with in vitro conditions. This loss of activity has been mainly associated with …


Vitamin D–Amp Axis In Host Defense Against Fungal Infections, Nuraly S. Akimbekov, Ilya Digel, Svetlana K. Sakhanova, Kuanysh Tastambek, Dinara K. Sherelkhan, Mohammed S. Razzaque Jun 2026

Vitamin D–Amp Axis In Host Defense Against Fungal Infections, Nuraly S. Akimbekov, Ilya Digel, Svetlana K. Sakhanova, Kuanysh Tastambek, Dinara K. Sherelkhan, Mohammed S. Razzaque

School of Medicine Publications

Vitamin D–mediated regulation of antimicrobial peptides (AMPs) is an important focus in innate immunology and is aimed at elucidating the role of vitamin D in enhancing antimicrobial defense. AMPs are short protein chains that serve as a first line of defense against invading pathogens, including fungi, bacteria and viruses. Unlike conventional antibiotics, AMPs are produced endogenously and are less likely to induce antimicrobial resistance, making them promising candidates for treating infections caused by drug-resistant pathogens. Studies indicate that optimal vitamin D levels are essential for activating antimicrobial pathways and regulating AMPs that target multiple fungal pathogens. This article summarizes recent …


Effects Of L-Baiba Supplementation With And Without Grains Of Paradise On Changes In Resting Metabolic Rate, Body Composition, And Cardiometabolic Risk Factors, Leah E. Allen, Paige J. Sutton, Alex Schrautemeier, Kevin Holley, Connor J. Gaige, Joesi M. Krieger, Anthony M. Hagele, Karenina Antequera Gutierrez, Petey Mumford, Chad Kerksick Jun 2026

Effects Of L-Baiba Supplementation With And Without Grains Of Paradise On Changes In Resting Metabolic Rate, Body Composition, And Cardiometabolic Risk Factors, Leah E. Allen, Paige J. Sutton, Alex Schrautemeier, Kevin Holley, Connor J. Gaige, Joesi M. Krieger, Anthony M. Hagele, Karenina Antequera Gutierrez, Petey Mumford, Chad Kerksick

Faculty Symposium

To evaluate the impact of 56 days of supplementing with L-BAIBA or L-BAIBA + GOP (BGOP) on resting metabolic rate, body composition, perceptual indicators of mood and affect, and cardiometabolic markers in overweight and obese men and women.

METHODS: Healthy men and women (43.2±11.4 years, 169.4±7.6 cm, 90.3±15.6 kg, 31.4±4.4 kg∙m-2) completed a weekly exercise program and followed a calorierestrictive diet and were randomly assigned in a double-blind and blocked manner according to sex and DXA lean mass to consume daily either a placebo (PLA) (n=12 [11F, 1M]), 500 mg L-BAIBA (L-BAIBA: MitoBurn™, NNB Nutrition) (n=13 [9F, 4M]), or …


Roots And Greens: Discovering The Power Of Indigenous Produce, Abiodun T. Atoloye, Sherif O. Olasoji, Ebunoluwa G. Ibidapo Jun 2026

Roots And Greens: Discovering The Power Of Indigenous Produce, Abiodun T. Atoloye, Sherif O. Olasoji, Ebunoluwa G. Ibidapo

Nutrition, Dietetics, and Food Sciences Courseware

The curriculum was designed in alignment with the Cognitive Theory of Multimedia Learning (CTML), Empowerment Theory (ET), and Social Cognitive Theory (SCT) frameworks. These frameworks were used to determine the selection and sequencing of learning activities. As reflected in CTML principles, the use of texts, images, infographics, and videos enhances knowledge retention and information comprehension and helps prevent cognitive overload. Through activities, homework, and family engagement, the principles of ET were incorporated into the curriculum to facilitate participants’ perceived control over food-related decisions. Additionally, by applying the principles of SCT, the curriculum incorporates scenario-based questions, opportunities to engage with peers, …


Community-Based Participatory Research In Developing Online Nutrition Tools: A Pathway To Relevance And Engagement, Laura Justice, Stacy Phillips May 2026

Community-Based Participatory Research In Developing Online Nutrition Tools: A Pathway To Relevance And Engagement, Laura Justice, Stacy Phillips

EFNEP

This article explains how Community-Based Participatory Research (CBPR) can strengthen the design of digital nutrition tools by ensuring they are culturally relevant, accessible, and grounded in community needs. By engaging participants as equal partners, CBPR enhances trust, usability, and long-term impact. The approach aligns with EFNEP’s mission to deliver inclusive, community-driven nutrition education and provides a framework for developing sustainable, adaptable tools that reflect the lived experiences of the families Extension serves.


The Association Between Diet Quality, Nutritional Knowledge, Low Energy Availability, And Eating Disorder Risk In Collegiate Student-Athletes, Laurel Koontz Awald May 2026

The Association Between Diet Quality, Nutritional Knowledge, Low Energy Availability, And Eating Disorder Risk In Collegiate Student-Athletes, Laurel Koontz Awald

Doctoral Dissertations and Projects

This study aimed to investigate the association between diet quality, nutritional knowledge, low energy availability, and eating disorder risk in a sample of collegiate student-athletes across several sporting disciplines. The quantitative cross-sectional survey was developed using validated questionnaires to investigate diet quality (The Athlete Diet Index), nutritional knowledge (The Platform for Evaluating Athlete Knowledge in Sports – Nutrition Questionnaire), low energy availability (The Low Energy Availability in Females Questionnaire and Low Energy Availability in Males Questionnaire), and eating disorder risk (DESA – 6). College athletes were recruited from Division I and III universities: (N = 31) from the track and …


Behavioral Science Applications In Collegiate Athlete Nutrition And Sleep: A Scoping Review, Maryam Yuhas, Katherine M. Kidwell, Olivia Moskuna, Rajib Mandal, Jessica L. Garay May 2026

Behavioral Science Applications In Collegiate Athlete Nutrition And Sleep: A Scoping Review, Maryam Yuhas, Katherine M. Kidwell, Olivia Moskuna, Rajib Mandal, Jessica L. Garay

Nutrition - All Scholarship

Nutrition and sleep are key health behaviors supporting athletic performance. Collegiate athletes in the United States (U.S.) are at high risk of insufficient dietary intake and nightly sleep given the competing demands of elite sports and academics. Researchers have developed interventions to improve collegiate athletes’ sleep and nutrition, either individually or collectively. However, progress in understanding how best to create sustained behavior change in this population has been slow. This may be due to the lack of application of behavioral science principles such as lack of a guiding theory, effective strategies, and consideration of implementation contexts. This scoping review takes …


Incorporating The Use Of Puppets And Puppetry-Based Approaches In Nutrition: A Scoping Review Of Interventions, Basil H. Aboul-Enein, Nada Benajiba, Majd Jan, Sarah Ali Alasmari, Patricia J. Kelly, Stephen F. Gambescia, Elizabeth Dodge May 2026

Incorporating The Use Of Puppets And Puppetry-Based Approaches In Nutrition: A Scoping Review Of Interventions, Basil H. Aboul-Enein, Nada Benajiba, Majd Jan, Sarah Ali Alasmari, Patricia J. Kelly, Stephen F. Gambescia, Elizabeth Dodge

College of Nursing Faculty Papers & Presentations

Puppetry-based activities could serve as a low cost and manageable intervention in improving health-related outcomes. This review aims to identify the research to date and gaps in practice of the role and application of puppetry interventions in nutrition education. A scoping review was conducted using the PICOS framework and PRISMA-ScR guidelines, identifying studies across eight databases between January, 1980 and July, 2025.Twenty-five studies were identified, with the majority (n = 19) aimed at pre-school and school-aged children. Fifteen studies used quasi-experimental, pre-post designs. The use of hand and finger puppets was common, as well as videos and puppet theatre. …


How Nutrition And Physical Activity Shape Your Well-Being, Stacy Phillips May 2026

How Nutrition And Physical Activity Shape Your Well-Being, Stacy Phillips

EFNEP

This publication will explore the link among nutrition, physical activity, physical health, and mental health and how it impacts whole-body well-being. Understanding how multiple aspects of a person's lifestyle can affect an individual's overall well-being is essential to providing better education on how to make better choices to improve their well-being.


Factors Associated With Stunting And Underweight Indices Among Children 0–3 Years In Nairobi, Kenya: A Cross-Sectional Study, Eunice Njoroge, Kevinson Mwangi, Esther Chongwo, Martha Kaniala, Kevin Wekesa, Isaac Lihanda, Vibian Angweny, Rachel Odhiambo, Margaret Kabue, Japhet Adina, Amina Abubakar May 2026

Factors Associated With Stunting And Underweight Indices Among Children 0–3 Years In Nairobi, Kenya: A Cross-Sectional Study, Eunice Njoroge, Kevinson Mwangi, Esther Chongwo, Martha Kaniala, Kevin Wekesa, Isaac Lihanda, Vibian Angweny, Rachel Odhiambo, Margaret Kabue, Japhet Adina, Amina Abubakar

Institute for Human Development, East Africa

Background:Childundernutritionremainsoneofthemostpressingglobalpublic health challenges, particularly in low and middle-income countries (LMICs). Most studies focus broadly on children under five, potentially overlooking the unique vulnerabilities a ecting children in the first 1,000 days of life. This study investigated potential factors associated with stunting and underweight malnutritional presentation among children aged 0–3 years in Nairobi City County, Kenya.

Methods: We conducted a cross-sectional study of 2903 caregiver-child dyads living in Nairobi City County to assess stunting [Height-for-Age Z-scores (HAZ)] and underweight [Weight-for-Age Z-scores (WAZ)] using the World Health Organisation (WHO) growth standards among 0–3-year-olds. Child, caregiver, and householdcharacteristicswereincludedinthelinearmixede ects regression models …


Food Insecurity On College Campus, Erika Islao, Izzy Green, Rachel Stone, Ariana Messer Apr 2026

Food Insecurity On College Campus, Erika Islao, Izzy Green, Rachel Stone, Ariana Messer

Celebrating Scholarship and Creativity Day (2018-)

Food Insecurity can affect certain groups more than others. At the College of Saint Benedict and Saint John's University we've observed it in international students, student-athletes, and those without transportation. Although CSBSJU offers several dining options, it can still be difficult for students to access meals due to limited availability during breaks, limited dining hours for student-athletes, and transportation barriers. This paper examines how food insecurity and nutrition insecurity impact students’ overall well-being while also exploring how these challenges appear within the CSBSJU community. Research shows that students experiencing food insecurity often report higher stress levels, and lower academic engagement. …


Mechanistic Insights Into Enterolactone-Mediated Glut4-Dependent Glucose Uptake, Merritt Smith Apr 2026

Mechanistic Insights Into Enterolactone-Mediated Glut4-Dependent Glucose Uptake, Merritt Smith

Senior Honors Theses

Type 2 diabetes mellitus (T2D) is one of the leading causes of morbidity and mortality in the United States, with approximately 25% of healthcare expenditures directed toward its management and associated metabolic complications. In response to the urgent need for novel therapeutic strategies, recent research has focused on bioactive compounds derived from dietary sources. In light of that, we identified the plant lignan matairesinol (MA) and its gut-derived metabolite, enterolactone (ENL), as agents capable of enhancing glucose uptake in 3T3-L1 differentiated adipocytes. These results suggest that enterolactone may represent a promising dietary supplement for improving glycemic control in patients with …


A Regional Scoping Review Of School-Based Nutrition Interventions Conducted Across Nordic Countries, Basil H. Aboul-Enein, Stephen Gambescia, Nada Benajiba, Norah Eid Aljohani, Teresa Keller, Patricia J. Kelly Apr 2026

A Regional Scoping Review Of School-Based Nutrition Interventions Conducted Across Nordic Countries, Basil H. Aboul-Enein, Stephen Gambescia, Nada Benajiba, Norah Eid Aljohani, Teresa Keller, Patricia J. Kelly

College of Nursing Faculty Papers & Presentations

BACKGROUND AND AIMS: While Nordic countries have a relatively high socioeconomic status population, they are challenged by the health deficit of rising obesity and overweight among young people. The aim of this regional scoping review is to identify best practices for designing and implementing effective school nutrition programs in Nordic countries and identify gaps for further research.

METHODS: Using the PRISMA-ScR guidelines, a scoping review was conducted across nine academic databases between 1980 and May 2025.

RESULTS: Fifty-three studies met the inclusion criteria, from small pilot interventions to large national or international cohorts involving thousands of students across the five …


Beetroot Juice And Vitamin C Co-Supplementation Enhances Anaerobic Performance And Reduces Post-Exercise Glycemia In Wrestlers: A Randomized, Double-Blind, Placebo-Controlled Crossover Trial, Maedeh Nojoumi, Ali Jafari, Alireza Hosseini Kakhiki, Ali Jafarzadeh Esfehani, Hossein Rafiei, Chad Kerksick, Oluwatoyosi Owoeye, Reza Rezvani Apr 2026

Beetroot Juice And Vitamin C Co-Supplementation Enhances Anaerobic Performance And Reduces Post-Exercise Glycemia In Wrestlers: A Randomized, Double-Blind, Placebo-Controlled Crossover Trial, Maedeh Nojoumi, Ali Jafari, Alireza Hosseini Kakhiki, Ali Jafarzadeh Esfehani, Hossein Rafiei, Chad Kerksick, Oluwatoyosi Owoeye, Reza Rezvani

Faculty Scholarship

Background

Wrestling, characterized by high-intensity intermittent efforts, demands exceptional anaerobic power and recovery capacity. Nitrate-rich beetroot juice (BRJ), supplemented with vitamin C, has emerged as a potential ergogenic aid through increased nitric oxide bioavailability. However, limited data exists regarding its acute effects on anaerobic performance in combat sport athletes. This study investigated the acute effects of BRJ supplemented with vitamin C on upper- and lower-body anaerobic test performance and selected biochemical markers in collegiate wrestlers.

Methods

In a randomized, double-blind, placebo-controlled crossover trial, 28 collegiate male wrestlers (18–24 years) consumed a single 250-ml BRJ drink (8.4 mmol nitrate + 90 …


Biol 210: Nutrition (Syllabus), Sam Newberry Ph.D. Apr 2026

Biol 210: Nutrition (Syllabus), Sam Newberry Ph.D.

School of Arts & Sciences

This syllabus was developed by SUNY Geneseo Professor Sam Newberry during the spring 2026 semester.

Course Learning Objectives:

Students who are active participants and complete course requirements will be able to: 

  1. Demonstrate familiarity with nutrients, their food sources, their functions, and signs and symptoms of deficiency or excess.
  2. Demonstrate familiarity with biological, psychological, social and cultural factors that influence human diet and nutrition.
  3. Describe and explain in class discussion and on exams the relationship between diet and health, particularly for selected public health issues.
  4. Demonstrate familiarity with nutritional guidelines used in the United States, and the challenges of establishing such …


Final Project: Nutrition And Human Disease, Sam Newberry Ph.D. Apr 2026

Final Project: Nutrition And Human Disease, Sam Newberry Ph.D.

School of Arts & Sciences

This assignment is made up of a series of smaller assignments that were developed by SUNY Geneseo Professor Sam Newberry during the spring 2026 semester.

Learning Objectives

  • Identify and demonstrate understanding of audience needs
  • Identify nutritional issues associated with human disease
  • Clear communication of information via an Infographic
  • Proper utilization of scholarly sources of information


Eating For Healthy Eyes: The Role Of Nutrition In Ocular Health, Brianna Stroh Apr 2026

Eating For Healthy Eyes: The Role Of Nutrition In Ocular Health, Brianna Stroh

Honors Program: Senior Projects (Public)

The central research question of this thesis asks: How does nutrition influence ocular health overall and the impact of nutrition on the development or progression of common eye diseases? Building upon existing research in optometry/ophthalmology, nutrition science, and public health, this project examines the physiological mechanisms linking diet to eye health and evaluates how specific nutrients and dietary patterns contribute to disease prevention and visual function. This thesis employs a comprehensive review of peer-reviewed literature to evaluate the relationship between nutrition and ocular disease. Key areas of focus include the role of oxidative stress in eye disease development, the protective …


Oral Multienzyme Supplementation Alters Postprandial Plasma Nutrient Concentrations After A Mixed Meal In Healthy Middle-Aged And Older Adults: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial, Max T. Deutz, Andrew T. Askow, Sean M. Garvey, David A. Alvarado, Takeshi M. Barnes, Zan Zupancic, Alexander V. Ulanov, Jared W. Willard, Hannah D. Holscher, Brett R. Loman, Nicholas A. Burd Apr 2026

Oral Multienzyme Supplementation Alters Postprandial Plasma Nutrient Concentrations After A Mixed Meal In Healthy Middle-Aged And Older Adults: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial, Max T. Deutz, Andrew T. Askow, Sean M. Garvey, David A. Alvarado, Takeshi M. Barnes, Zan Zupancic, Alexander V. Ulanov, Jared W. Willard, Hannah D. Holscher, Brett R. Loman, Nicholas A. Burd

Kinesiology & Sport Management Scholarship

Background: Age-related decline in digestive function increases malnutrition risk. Supplementing meals with digestive enzymes may improve macronutrient digestion and bioavailability in adults reaching older ages.

Objectives: To assess postprandial plasma nutrient concentrations after co-ingestion of a mixed meal and a mixture of 6 enzyme preparations (ENZ), including proteases, lipase, amylase, and glucoamylase.

Methods: Thirty middle-aged and older adults (56 ± 11 y; 18 females, 12 males) ingested chicken, peas, potatoes, and butter (435 kcal; 34 g protein, 51 g carbohydrate, 11 g fat) with either ENZ or placebo (PLA) in a randomized crossover fashion. Blood samples were collected …


Dietary Influence And Neurodegenerative Disease Risk: Insight From Alzheimer’S And Parkinson’S Disease, Madison Wirt Apr 2026

Dietary Influence And Neurodegenerative Disease Risk: Insight From Alzheimer’S And Parkinson’S Disease, Madison Wirt

Honors Projects

As populations age, neurodegenerative diseases (NDD) become significantly more prevalent and impactful on patients and families. Clinical research has suggested a correlation between diet, gut health, neuroinflammation and mitochondrial dysfunction to the onset and development of specific and severe NDDs, especially Alzheimer’s disease (AD) and Parkinson’s disease (PD). This research focuses on the relationship behind the gut-brain axis, micronutrient status and how diet influences the development of both AD and PD. Ten randomized, controlled trials were analyzed from the literature to investigate the impact of these factors on the inflammatory, metabolic and antioxidant processes. The studies focused on the use …


Weaning Drives Microbiome-Mediated Epigenetic Regulation To Shape Immune Memory In Mice, Li Yang, Robert C Peery, Shirui Zhou, Xiaomin Chen, Leah M Farmer, Fabiola Gutierrez, Stephanie Fowler, Lanjing Zhang, Julia M Salamat, Karen Riggins, Jiejun Shi, Lanlan Shen Apr 2026

Weaning Drives Microbiome-Mediated Epigenetic Regulation To Shape Immune Memory In Mice, Li Yang, Robert C Peery, Shirui Zhou, Xiaomin Chen, Leah M Farmer, Fabiola Gutierrez, Stephanie Fowler, Lanjing Zhang, Julia M Salamat, Karen Riggins, Jiejun Shi, Lanlan Shen

Children’s Nutrition Research Center Staff Publications

During weaning, the transition to solid food diversifies the gut microbiome, triggering a programmed immune response critical for long-lasting mucosal immunity. Previous work showed that the gut microbiome mediates epigenetic development in intestinal stem cells (ISCs) during suckling, but what happens during weaning is unclear. Here, genome-wide profiling revealed that weaning-driven microbiome changes shape the DNA methylome and transcriptome of murine ISCs in an IFNγ-dependent manner. Specifically, we observe demethylation of enhancer elements essential for MHC class II genes, which results in a transcriptional memory that persists through differentiation into adulthood. IFNγ blockade, or low-dose penicillin to target Gram-positive bacteria, …


3'Utr Mapping Reveals Alternative Polyadenylation In Right Ventricular Failure, Rahul Neupane, Kartiga Natarajan, Erik E Suarez, Henry J Pownall, Kai-Lieh Huang, Eric J Wagner, Ajay Kumar Verma, Rambabu Majji, Hari Krishna Yalamanchili, Ashrith Guha, Rajarajan A Thandavarayan Mar 2026

3'Utr Mapping Reveals Alternative Polyadenylation In Right Ventricular Failure, Rahul Neupane, Kartiga Natarajan, Erik E Suarez, Henry J Pownall, Kai-Lieh Huang, Eric J Wagner, Ajay Kumar Verma, Rambabu Majji, Hari Krishna Yalamanchili, Ashrith Guha, Rajarajan A Thandavarayan

Children’s Nutrition Research Center Staff Publications

No abstract provided.


Associations Between Reported Use Of Nutritional Labels And Calorie Intake In Us Adults: Findings From Nhanes 2017–2020, Ariana M. Chao, Nancy Greene, Alexandra Paul, Paule V. Joseph Mar 2026

Associations Between Reported Use Of Nutritional Labels And Calorie Intake In Us Adults: Findings From Nhanes 2017–2020, Ariana M. Chao, Nancy Greene, Alexandra Paul, Paule V. Joseph

College of Nursing Faculty Papers & Presentations

Objective: Caloric information is commonly displayed on nutritional fact labels and food menus. Yet evidence is limited on whether label use is associated with a reduced-calorie diet. This study examined the associations between the use of caloric information on nutritional facts and menu labels and daily caloric intake. Methods: We used data from adults in the National Health and Nutrition Examination Survey (NHANES) 2017–2020 to conduct a cross-sectional study. Calorie label use on nutritional labels and menus was assessed using the Flexible Consumer Behavior Survey telephone interview. Caloric intake was evaluated using the mean of two 24-h diet recalls implemented …


Misregulated Alternative Splicing In Endometriosis: A Role For Aberrant Mrna Variants In Endometriotic Cell Growth, Venkata Naga Goutham Davuluri, Michelle Dias, Roxanna Llinas, Kamath Neha, Pooja Popli, Shannon M Hawkins, Chandrakant Tayade, Elise T Courtois, Hari Krishna Yalamanchili, Ramakrishna Kommagani Mar 2026

Misregulated Alternative Splicing In Endometriosis: A Role For Aberrant Mrna Variants In Endometriotic Cell Growth, Venkata Naga Goutham Davuluri, Michelle Dias, Roxanna Llinas, Kamath Neha, Pooja Popli, Shannon M Hawkins, Chandrakant Tayade, Elise T Courtois, Hari Krishna Yalamanchili, Ramakrishna Kommagani

Children’s Nutrition Research Center Staff Publications

Endometriosis is a chronic gynecological disorder marked by the growth of endometrial-like tissue outside the uterus, often leading to pelvic pain, inflammation, and infertility. Despite its global prevalence, diagnosis remains delayed, and effective non-surgical treatments are lacking. While recent transcriptomic studies have identified mRNA transcript changes in ectopic lesions, the contribution of alternative pre-mRNA splicing, a key posttranscriptional regulatory layer, remains largely unknown. In this study, we performed a comprehensive analysis of alternative splicing (AS) events in endometriotic lesions using transcriptomic data. We uncovered distinct alterations in alternative splicing events are associated with endometriosis, highlighting a previously underappreciated layer of …