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Full-Text Articles in Nutrition

Racial–Ethnic Disparities In Prediabetes And Diabetes Among Us Adults, Carly Selleck, Jennifer R. Mcatee, Weiwen Chai Apr 2020

Racial–Ethnic Disparities In Prediabetes And Diabetes Among Us Adults, Carly Selleck, Jennifer R. Mcatee, Weiwen Chai

UCARE: Research Products

Type-2 diabetes is a chronic metabolic disease affecting more than3 4 million Americans or 10.5% of the population [1]. While almost 90% of people are not aware of their prediabetes status, around 88 million adults are considered to be prediabetic [2]. Without any prevention methods, 70% of prediabetes cases will eventually develop into diabetes[3]. While the development of type-2 diabetes is multifactorial, lifestyle factors such as diet and physical activity as well as socioeconomic (SES) factors such as poverty and education can be main contributors [4]. This study aimed to assess racial-ethnic differences in SES, lifestyle factors and prevalence of …


Use Of A Novel Whole-Body Imaging Approach To Predict Resting Metabolic Rates In Athletes, Nicole Vencil Apr 2020

Use Of A Novel Whole-Body Imaging Approach To Predict Resting Metabolic Rates In Athletes, Nicole Vencil

College of Education and Human Sciences: Dissertations, Theses, and Student Research

Prediction of energy expenditure allows for calculation of appropriate energy requirements, which is especially important for athletes. Resting metabolic rate (RMR) is the greatest contributor to total daily energy expenditure (TDEE) and is typically measured via indirect calorimetry. Indirect calorimetry is not always available, which results in the need for predictive equations. Most predictive equations have been developed with participants resembling the general population and have not been found to be appropriate for athletes, as they may incorrectly predict RMR due to the unique differences of body composition between athletes and the general population. The purpose of the present study …


Mothers’ Experience With Infant Complementary Feeding Practices: A Phenomenological Study., Tyler Martin Apr 2020

Mothers’ Experience With Infant Complementary Feeding Practices: A Phenomenological Study., Tyler Martin

Department of Nutrition and Health Sciences: Dissertations, Theses, and Student Research

Background. Complementary feeding practices include what, when, and how to feed (Birch and Doub, 2014). The gradual transition from feeding exclusively human milk, formula milk, or a combination of both to complementary foods over the first 24 months of life is necessary to ensure proper growth and development (Dewey, 2001; Pearce & Langley-Evans, 2013). While research does exist on complementary feeding, such as infant diet composition, limited research exists on exploring complementary feeding practices from first-time mothers’ experiences.

Methods. This study utilized transcendental phenomenological qualitative research methodology. A pilot tested semi-structured interview guide was used to examine demographics as …


Caloric Restriction Induces Anabolic Resistance To Resistance Exercise, Chaise Murphy, Karsten Koehler Mar 2020

Caloric Restriction Induces Anabolic Resistance To Resistance Exercise, Chaise Murphy, Karsten Koehler

Department of Nutrition and Health Sciences: Faculty Publications

Purpose Weight loss can result in the loss of muscle mass and bone mineral density. Resistance exercise is commonly prescribed to attenuate these effects. However, the anabolic endocrine response to resistance exercise during caloric restriction has not been characterized. Methods Participants underwent 3-day conditions of caloric restriction (15 kcal kg FFM−1) with post-exercise carbohydrate (CRC) and with post-exercise protein (CRP), and an energy balance control (40 kcal kg FFM−1) with post-exercise carbohydrate (CON). Serial blood draws were taken following five sets of five repetitions of the barbell back squat exercise on day 3 of each condition. …


Protective Role Of Shiitake Mushroom-Derived Exosome-Like Nanoparticles In D-Galactosamine And Lipopolysaccharide-Induced Acute Liver Injury In Mice, Baolong Liu, Yizhu Lu, Xingyi Chen, Philma Glora Muthuraj, Xingzhi Li, Mahesh Pattabiraman, Janos Zempleni, Stephen D. Kachman, Sathish Kumar Natarajan, Jiujiu Yu Feb 2020

Protective Role Of Shiitake Mushroom-Derived Exosome-Like Nanoparticles In D-Galactosamine And Lipopolysaccharide-Induced Acute Liver Injury In Mice, Baolong Liu, Yizhu Lu, Xingyi Chen, Philma Glora Muthuraj, Xingzhi Li, Mahesh Pattabiraman, Janos Zempleni, Stephen D. Kachman, Sathish Kumar Natarajan, Jiujiu Yu

Department of Nutrition and Health Sciences: Faculty Publications

Fulminant hepatic failure (FHF) is a rare, life-threatening liver disease with a poor prognosis. Administration of D-galactosamine (GalN) and lipopolysaccharide (LPS) triggers acute liver injury in mice, simulating many clinical features of FHF in humans; therefore, this disease model is often used to investigate potential therapeutic interventions to treat FHF. Recently, suppression of the nucleotide-binding domain and leucine-rich repeat related (NLR) family, pyrin domain containing 3 (NLRP3) inflammasome, was shown to alleviate the severity of GalN/LPS-induced liver damage in mice. Therefore, the goal of this study was to find dietary exosome-like nanoparticles (ELNs) with therapeutic potential in curbing FHF by …


Healthy Pregnancies And Essential Fats: Focus Group Discussions With Zambian Women On Dietary Need And Acceptability Of A Novel Rusf Containing Fish Oil Dha, Catherine Chunda-Liyoka, Mwansa Ketty Lubeya, Mercy Imakando, Sophia Kisling, Sonoor Majid, Mary Willis, Charles Wood, Chipepo Kankasa, Concetta C. Dirusso Feb 2020

Healthy Pregnancies And Essential Fats: Focus Group Discussions With Zambian Women On Dietary Need And Acceptability Of A Novel Rusf Containing Fish Oil Dha, Catherine Chunda-Liyoka, Mwansa Ketty Lubeya, Mercy Imakando, Sophia Kisling, Sonoor Majid, Mary Willis, Charles Wood, Chipepo Kankasa, Concetta C. Dirusso

Department of Nutrition and Health Sciences: Faculty Publications

Background: Nut butter-based Ready to Use Supplemental Foods (RUSF) are an effective way to add nutrients and calories to diets of malnourished and food insecure populations. The RUSF formulations have been further modified to add micronutrients including iron and folic acid needed during pregnancy and lactation. Because docosahexaenoic acid (DHA, C22:6 n-3) enhances fetal development and birth outcomes, it has been suggested that perhaps RUSF formulations for pregnancy should also include this Omega 3 fatty acid. The goal of the present study was to gain an understanding of Zambian women’s knowledge of nutritional needs in pregnancy through structured focus group …


The Effects Of Asparagus Racemosus Supplementation Plus 8 Weeks Of Resistance Training On Muscular Strength And Endurance, John Paul V. Anders, Joshua L. Keller, Cory M. Smith, Ethan C. Hill Phd, Terry J. Housh, Richard J. Schmidt, Glen O. Johnson Jan 2020

The Effects Of Asparagus Racemosus Supplementation Plus 8 Weeks Of Resistance Training On Muscular Strength And Endurance, John Paul V. Anders, Joshua L. Keller, Cory M. Smith, Ethan C. Hill Phd, Terry J. Housh, Richard J. Schmidt, Glen O. Johnson

Department of Nutrition and Health Sciences: Faculty Publications

Previous studies have demonstrated that ayurvedic ingredients exhibit ergogenic (performance enhancing) properties, however, no previous studies have examined the ergogenic potential of Asparagus racemosus. The purpose of the present study was to examine the ergogenic efficacy of supplementation with 500 mg·d−1 of A. racemosus during bench press training. Eighteen recreationally trained men (mean ± SD; age = 20.4 ± 0.5 yrs; height = 179.7 ± 1.5 cm; weight = 84.7 ± 5.7 kg) were randomly assigned either 500 mg·d−1 of A. racemosus (n = 10) or placebo (n = 8). An overlapping sample of 10 participants were used to determine …


Alpha-Linolenic Acid-Enriched Butter Promotes Fatty Acid Remodeling And Thermogenic Activation In The Brown Adipose Tissue, Mikyoung You, Rong Fan, Judy Kim, Seung-Ho Shin, Soonkyu Chung Jan 2020

Alpha-Linolenic Acid-Enriched Butter Promotes Fatty Acid Remodeling And Thermogenic Activation In The Brown Adipose Tissue, Mikyoung You, Rong Fan, Judy Kim, Seung-Ho Shin, Soonkyu Chung

Department of Nutrition and Health Sciences: Faculty Publications

Supplementation with n-3 long-chain (LC) polyunsaturated fatty acids (PUFA) is known to promote thermogenesis via the activation of brown adipose tissue (BAT). Agricultural products that are biofortified with α-linolenic acid (ALA), the precursor of n-3 LC PUFA, have been launched to the market, but their impact on BAT function is unknown. This study aimed to evaluate the effects of ALA-biofortified butter on lipid metabolism and thermogenic functions in the BAT. C57BL/6 mice were fed a high-fat diet containing ALA-biofortified butter (n3Bu, 45% calorie from fat) for ten weeks in comparison with the isocaloric high-fat diets prepared from conventional butter or …


Dental Health Factors Among Primary School Children In Southern Regions Of Ethiopia And Zambia, Gisselle Hernandez Jan 2020

Dental Health Factors Among Primary School Children In Southern Regions Of Ethiopia And Zambia, Gisselle Hernandez

NUTR/GLST 498b: Global Research Experiences in Nutrition and Health

Purpose: Assess oral health status, and factors affecting oral health, among primary schoolchildren in southern Ethiopia and Zambia. Methods: Visual dental assessments, anthropometric measurements, and questionnaires used to collect data among 6th and 7th grade students. Results: Although stunting rates were nearly equal, decay rates were not; 17.51% of Zambian students and 47.27% of Ethiopian students had one or more decayed teeth. Ethiopian students with dental fluorosis (74.55%) had higher rates of decay than those without the condition (p < .05). There were also significant differences between Ethiopians and Zambians regarding use of dental hygiene tools: Ethiopians were more likely to use dental sticks, while Zambians employed toothbrushes for cleaning. Conclusions: Dental health and hygiene education, focused on unique socioecological settings, could improve the oral health status of Ethiopian and Zambian children.

PowerPoint file attached below


Iron-Rich Foods, Anemia, And Malaria In Primary School Children In Southern Ethiopia And Zambia, Julianne Fay Jan 2020

Iron-Rich Foods, Anemia, And Malaria In Primary School Children In Southern Ethiopia And Zambia, Julianne Fay

NUTR/GLST 498b: Global Research Experiences in Nutrition and Health

PURPOSE: To examine the relationship between iron-deficient anemia and malaria in primary school children in Southern Ethiopia and Zambia and assess the correlation between diet and health status.

METHODS: Market inventories, observations at health outposts, and interviews and anthropometric assessments of 6th and 7th grade students.

RESULTS: Both Ethiopia and Zambia had 20 iron-rich foods available in local markets. Only liver consumption was associated with malaria experience; those who consumed liver were significantly less likely to have had the disease (p

DISCUSSION: Given the high prevalence of malaria in Southern Ethiopia and Zambia, and the correlation between liver consumption and …


Nutrition And Attendance For Primary School Students In Ethiopia And Zambia, Lillie Tronnes Jan 2020

Nutrition And Attendance For Primary School Students In Ethiopia And Zambia, Lillie Tronnes

NUTR/GLST 498b: Global Research Experiences in Nutrition and Health

Introduction: Nutrition impacts attendance for primary school students in Southern Ethiopia and Zambia. Food insecurity causes school-age children to be undernourished, malnourished, and stunted. These health concerns greatly impact ability to attend and perform in school.

Methods: Between May and June of 2019 6th and 7th grade students were surveyed within 4 schools in Ethiopia and 5 schools in Zambia. Anthropometric data, health history, and nutritional habits were surveyed.

Results: 8% of Ethiopian students were stunted while 10% of Zambian students were stunted. Ethiopian students indicated school lunch was an incentive while Zambian students did not. Most …


Eastern North Carolina Head Start Teachers’ Personal And Professional Experiences With Healthy Eating And Physical Activity: A Qualitative Exploration, Virginia C. Stage, Lorelei Jones, Jocelyn Bayles, Archana V. Hegde, Dipti Dev, L. Suzanne Goodell Jan 2020

Eastern North Carolina Head Start Teachers’ Personal And Professional Experiences With Healthy Eating And Physical Activity: A Qualitative Exploration, Virginia C. Stage, Lorelei Jones, Jocelyn Bayles, Archana V. Hegde, Dipti Dev, L. Suzanne Goodell

Department of Child, Youth, and Family Studies: Faculty Publications

Objective: Explore the interrelationship between teachers’ personal and professional socio-ecological structures while examining Head Start (HS) teachers’ experiences with (1) trying to eat healthy and engage in physical activity (PA) and (2) promote healthy eating and PA in their classrooms.

Design: In-depth semi-structured interviews were collected from March through June 2017. Researchers designed the data collection and analysis methods using a phenomenological approach. All interviews were recorded using digital audio and transcribed verbatim.

Setting: Seven HS centers in two rural eastern North Carolina counties.

Participants: Teachers (n 15) who had recently participated in a healthy eating and physical activity …


Nutritional Strategies For Nurses In A Fast Paced Occupation, Zachary Christman Jan 2020

Nutritional Strategies For Nurses In A Fast Paced Occupation, Zachary Christman

Department of Agronomy and Horticulture: Dissertations, Theses, and Student Research

The foundation of the medical system are the nurses and certified medical assistants. Their personal health condition affects how well diseases and other medical conditions are handled. This article will begin with an overview of the eating behavior of nurses. Three different interventions which have been shown effective in a fast paced workplace are presented in order to improve the health of nurses and certified medical assistants. The first intervention is organizational changes that would increase the amount of time nursing staff have to eat. The second is the use of a messenger bag delivery system to provide needed food, …


A Review Of Technologies For Malt Flour And Sourdough From Brewery Spent Grain, Zachary Christman Jan 2020

A Review Of Technologies For Malt Flour And Sourdough From Brewery Spent Grain, Zachary Christman

Department of Agronomy and Horticulture: Dissertations, Theses, and Student Research

The utilization of brewer's spent grain for the production of malt flour is the focus of this article. The reader is presented with superheated steam and extrusion as technologies to reduce mycotoxin contamination and improve shelf life. Another option is the fermentation of brewer's spent grain with a cereal grade lactic acid bacteria for the production of sourdough bread. Milling of the brewer's spent grain for the production of bread is also covered.


Association Of Home Food Availability With Prediabetes And Diabetes Among Adults In The United States, Jennifer R. Mcatee, Meng-Hua Tao, Christian King, Weiwen Chai Jan 2020

Association Of Home Food Availability With Prediabetes And Diabetes Among Adults In The United States, Jennifer R. Mcatee, Meng-Hua Tao, Christian King, Weiwen Chai

Department of Nutrition and Health Sciences: Faculty Publications

This study examined associations of home food availabilities with prediabetes and diabetes among 8929 adults (20–70 years) participating in 2007–2010 National Health and Nutrition Examination Surveys. Odds ratios (ORs) and 95% confidence intervals (95% CIs) were estimated by logistic regression. Relative to non-diabetic participants (individuals without diabetes or prediabetes), prediabetes participants were associated with lower availabilities of green vegetables (OR = 0.82; 95% CI = 0.73–0.91; p = 0.0006) and fat-free/low-fat milk (OR = 0.80, 95% CI = 0.65–0.89; p = 0.001) and higher sugary drink availability (OR = 1.24, 95% CI = 1.04–1.48; p = 0.02), adjusting for age, …


Endogenous Versus Exogenous Carbohydrate Oxidation Measured By Stable Isotopes In Pre-Pubescent Children Plus 13c Abundances In Foods Consumed Three Days Prior, Marni E. Shoemaker, Zachary M. Gillen, Brianna D. Mckay, Todd J. Leutzinger, Vikkie A. Mustad, Joel T. Cramer Jan 2020

Endogenous Versus Exogenous Carbohydrate Oxidation Measured By Stable Isotopes In Pre-Pubescent Children Plus 13c Abundances In Foods Consumed Three Days Prior, Marni E. Shoemaker, Zachary M. Gillen, Brianna D. Mckay, Todd J. Leutzinger, Vikkie A. Mustad, Joel T. Cramer

Department of Nutrition and Health Sciences: Faculty Publications

Purpose: The purposes of the present study were to (a) examine resting metabolism, substrate utilization, and endogenous versus exogenous carbohydrate (CHO) oxidation before and after 30-g rapidly-digesting carbohydrate (RDC) ingestion using indirect calorimetry and breath test analysis of stable isotope concentrations in pre-pubescent children and (b) report the 13C abundances in foods consumed for three days prior.

Methods: Nineteen children (n 1⁄4 10 boys, n 1⁄4 9 girls) at Tanner stage I or II participated (mean age ± 95% CI 1⁄4 9.84 ± 0.77 y) in this study. Food was administered to the children for three days preceding their scheduled …


Eb4cast Approach Improves Science Communication With Stakeholders In A College-Based Health Program, Melissa D. Olfert, Makenzie L. Barr, Rebecca L. Hagedorn, Rahel A. Wattick, Wenjun Zhou, Tanya M. Horacek, Anne E. Mathews, Kendra K. Kattlemann, Tandalayo Kidd, Adrienne A. White, Onikia N. Brown, Jesse Stabile Morrell, Lisa Franzen-Castle, Karla P. Shelnutt, Carol Byrd-Bredbenner, Terezie Tolar-Peterson, Geoffrey W. Greene, Sarah E. Colby Jan 2020

Eb4cast Approach Improves Science Communication With Stakeholders In A College-Based Health Program, Melissa D. Olfert, Makenzie L. Barr, Rebecca L. Hagedorn, Rahel A. Wattick, Wenjun Zhou, Tanya M. Horacek, Anne E. Mathews, Kendra K. Kattlemann, Tandalayo Kidd, Adrienne A. White, Onikia N. Brown, Jesse Stabile Morrell, Lisa Franzen-Castle, Karla P. Shelnutt, Carol Byrd-Bredbenner, Terezie Tolar-Peterson, Geoffrey W. Greene, Sarah E. Colby

Department of Nutrition and Health Sciences: Faculty Publications

Communicating scientific results with community partners is often lacking in intervention programs, thus eB4CAST was developed to facilitate impact sharing. This article investigated using the eB4CAST dissemination tool to communicate impact from a campus-based obesity prevention program. Data from Get Fruved RCT university sites collected at baseline were used to generate eB4CAST reports. Experts (n = 13) and RCT sites (n = 15) were asked to provide feedback on eB4CAST reports based on appeal, understanding, and clarity. On all Likert items, participants rated above 7 on each (out of 10). Positive responses from open-ended questions included eB4CAST reports being clear, …


R-Α-Lipoic Acid And 4-Phenylbutyric Acid Have Distinct Hypolipidemic Mechanisms In Hepatic Cells, Bo He, Régis Moreau Jan 2020

R-Α-Lipoic Acid And 4-Phenylbutyric Acid Have Distinct Hypolipidemic Mechanisms In Hepatic Cells, Bo He, Régis Moreau

Department of Nutrition and Health Sciences: Faculty Publications

The constitutive activation of the mechanistic target of rapamycin complex 1 (mTORC1) leads to the overproduction of apoB-containing triacylglycerol-rich lipoproteins in HepG2 cells. R-α-lipoic acid (LA) and 4-phenylbutyric acid (PBA) have hypolipidemic function but their mechanisms of action are not well understood. Here, we reported that LA and PBA regulate hepatocellular lipid metabolism via distinct mechanisms. The use of SQ22536, an inhibitor of adenylyl cyclase, revealed cAMP’s involvement in the upregulation of CPT1A expression by LA but not by PBA. LA decreased the secretion of proprotein convertase subtilisin/kexin type 9 (PCSK9) in the culture media of hepatic cells and increased …


Single-Arm, Non-Randomized, Time Series, Single-Subject Study Of Fecal Microbiota Transplantation In Multiple Sclerosis, Phillip A. Engen, Antonia Zaferiou, Heather Rasmussen, Ankur Ankub, Stefan J. Green, Louis F. Fogg, Christopher B. Forsyth, Shohreh Raeisi, Bruce Hamaker, Ali Keshavarzian Jan 2020

Single-Arm, Non-Randomized, Time Series, Single-Subject Study Of Fecal Microbiota Transplantation In Multiple Sclerosis, Phillip A. Engen, Antonia Zaferiou, Heather Rasmussen, Ankur Ankub, Stefan J. Green, Louis F. Fogg, Christopher B. Forsyth, Shohreh Raeisi, Bruce Hamaker, Ali Keshavarzian

Department of Nutrition and Health Sciences: Faculty Publications

Emerging evidence suggests intestinal microbiota as a central contributing factor to the pathogenesis of Relapsing-Remitting-Multiple-Sclerosis (RRMS). This novel RRMS study evaluated the impact of fecal-microbiota-transplantation (FMT) on a broad array of physiological/clinical outcomes using deep metagenome sequencing of fecal microbiome. FMT interventions were associated with increased abundances of putative beneficial stool bacteria and short-chain-fatty-acid metabolites, which were associated with increased/improved serum brain-derived-neurotrophic-factor levels and gait/walking metrics. This proof-of-concept single-subject longitudinal study provides evidence of potential importance of intestinal microbiota in the pathogenesis of MS, and scientific rationale to help design future randomized controlled trials assessing FMT in RRMS patients.


Application Of The Neuromuscular Fatigue Threshold Treadmill Test To Muscles Of The Quadriceps And Hamstrings, Clayton L. Camic, Attila J. Kovacs, Trisha A. Vandusseldorp, Ethan C. Hill Phd, Evan A. Enquist Jan 2020

Application Of The Neuromuscular Fatigue Threshold Treadmill Test To Muscles Of The Quadriceps And Hamstrings, Clayton L. Camic, Attila J. Kovacs, Trisha A. Vandusseldorp, Ethan C. Hill Phd, Evan A. Enquist

Department of Nutrition and Health Sciences: Faculty Publications

Purpose: The purposes of the present study were: (1) to determine whether the physical working capacity at the fatigue threshold (PWCFT) model that has been used for estimating the onset of neuromuscular fatigue in the vastus lateralis (VL) during incremental treadmill running could also be applied to the vastus medialis (VM), biceps femoris (BF), and semitendinosus (ST) muscles; and (2) if applicable, to compare the running velocities associated with the PWCFT among these muscles.

Methods: Eleven subjects (age 21.7 ± 1.8 years) performed an incremental treadmill test to exhaustion with electromyographic signals recorded from the …


Ipsilateral And Contralateral Torque Responses To Bilateral And Unilateral Maximal, Fatiguing, Isokinetic Leg Extensions, Tyler J. Neltner, John Paul V. Anders, Joshua L. Keller, Robert W. Smith, Terry J. Housh, Richard J. Schmidt, Glen O. Johnson Jan 2020

Ipsilateral And Contralateral Torque Responses To Bilateral And Unilateral Maximal, Fatiguing, Isokinetic Leg Extensions, Tyler J. Neltner, John Paul V. Anders, Joshua L. Keller, Robert W. Smith, Terry J. Housh, Richard J. Schmidt, Glen O. Johnson

Department of Nutrition and Health Sciences: Faculty Publications

Background: Few studies have compared performance fatigability (PF) for bilateral versus unilateral isokinetic tasks. Objectives: The purpose of this study was to examine: Mode- specific testing responses to isokinetic fatigue, differences in PF between bilateral and unilateral leg extensions, and the effects of fatiguing, unilateral, dynamic leg extensions on contralateral isokinetic peak torque (PT) and maximal voluntary isometric contraction (MVIC). Methods: Eight men (mean ± SD: age= 22.5 ± 2.5 yr.) completed pre- and post-testing for PT and MVIC following 50 bilateral, unilateral right or left leg maximal, isokinetic leg extensions at 180°·s-1, on three separate days. Fatigue-induced decreases in …


Application Of The Neuromuscular Fatigue Threshold Treadmill Test To Muscles Of The Quadriceps And Hamstrings, Clayton L. Camic, Attila J. Kovacs, Trisha A. Vandusseldorp, Ethan C. Hill, Evan A. Enquist Jan 2020

Application Of The Neuromuscular Fatigue Threshold Treadmill Test To Muscles Of The Quadriceps And Hamstrings, Clayton L. Camic, Attila J. Kovacs, Trisha A. Vandusseldorp, Ethan C. Hill, Evan A. Enquist

Department of Nutrition and Health Sciences: Faculty Publications

Purpose: The purposes of the present study were: (1) to determine whether the physical working capacity at the fatigue threshold (PWCFT) model that has been used for estimating the onset of neuromuscular fatigue in the vastus lateralis (VL) during incremental treadmill running could also be applied to the vastus medialis (VM), biceps femoris (BF), and semitendinosus (ST) muscles; and (2) if applicable, to compare the running velocities associated with the PWCFT among these muscles.

Methods: Eleven subjects (age 21.7 § 1.8 years) performed an incremental treadmill test to exhaustion with electromyographic signals recorded from the VL, VM, BF, and ST. …


Urban Food Sovereignty: Urgent Need For Agroecology And Systems Thinking In A Post-Covid-19 Future, Ali Loker, Charles A. Francis Jan 2020

Urban Food Sovereignty: Urgent Need For Agroecology And Systems Thinking In A Post-Covid-19 Future, Ali Loker, Charles A. Francis

Department of Agronomy and Horticulture: Faculty Publications

The current COVID-19 pandemic has brought attention to challenges associated with our dominant industrial food system in the U.S. The general public now has more appreciation for farm workers and meatpacking employees, as well as those in grocery stores and in food transportation who are suddenly recognized as essential frontline workers. It apparently takes a crisis for us to focus clearly on the fragility of this system and the lives of people on whom we depend. In this commentary we discuss the definition of food sovereignty, how it manifests in urban areas, and how the COVID-19 pandemic can trigger viable …


Association Of Serum Γ-Tocopherol Levels With Mortality: The Multiethnic Cohort Study, Weiwen Chai, Gertraud Maskarinec, Adrian A. Franke, Kristine R. Monroeuniversity Of Southern California, Song-Yi Park, Laurence N. Kolonel, Lynne R. Wilkens, Loïc Le Marchand, Robert V. Cooney Dec 2019

Association Of Serum Γ-Tocopherol Levels With Mortality: The Multiethnic Cohort Study, Weiwen Chai, Gertraud Maskarinec, Adrian A. Franke, Kristine R. Monroeuniversity Of Southern California, Song-Yi Park, Laurence N. Kolonel, Lynne R. Wilkens, Loïc Le Marchand, Robert V. Cooney

Department of Nutrition and Health Sciences: Faculty Publications

Background/Objectives—γ-Tocopherol has unique properties that protect against nitrogen oxide-mediated cellular damage. To elucidate the potential role of γ-tocopherol in the aging process, we examined the associations of serum γ-tocopherol levels with all-cause and cause-specific mortality.

Subjects/Methods—Among participants in the biorepository subcohort of the Multiethnic Cohort Study, pre-cancer diagnostic serum γ-tocopherol levels were measured in a subset of 3904 men and 4461 women. Of these, 22.7% of men and 13.5% of women died during a mean follow- up time of 9.6±2.6 years. Hazard ratios (HRs) and 95% confidence intervals (95%CIs) for mortality associated with γ-tocopherol were estimated by Cox proportional hazards …


Dietary Depletion Of Milk Exosomes And Their Microrna Cargos Elicits A Depletion Of Mir-200a-3p And Elevated Intestinal Inflammation And Chemokine (C-X-C Motif) Ligand 9 Expression In Mdr1a−/− Mice, Di Wu, Hatem Kittana, Jiang Shu, Stephen D. Kachman, Juan Cui, Amanda E. Ramer-Tait, Janos Zempleni Oct 2019

Dietary Depletion Of Milk Exosomes And Their Microrna Cargos Elicits A Depletion Of Mir-200a-3p And Elevated Intestinal Inflammation And Chemokine (C-X-C Motif) Ligand 9 Expression In Mdr1a−/− Mice, Di Wu, Hatem Kittana, Jiang Shu, Stephen D. Kachman, Juan Cui, Amanda E. Ramer-Tait, Janos Zempleni

Department of Nutrition and Health Sciences: Faculty Publications

Background: Exosomes transfer regulatory microRNAs (miRs) from donor cells to recipient cells. Exosomes and miRs originate from both endogenous synthesis and dietary sources such as milk. miR-200a-3p is a negative regulator of the proinflammatory chemokine (C-X-C motif) ligand 9 (CXCL9). Male Mdr1a−/− mice spontaneously develop clinical signs of inflammatory bowel disease (IBD).

Objectives: We assessed whether dietary depletion of exosomes and miRs alters the severity of IBD in Mdr1a−/− mice owing to aberrant regulation of proinflammatory cytokines.

Methods: Starting at 5 wk of age, 16 male Mdr1a−/− mice were fed either milk exosome– and RNA-sufficient (ERS) or milk exosome– and …


The Development And Implementation Of “Mission Nutrition”: An After-School Nutrition Education Program For Youth Grades Kindergarten Through Fifth, Rachel Maloy Oct 2019

The Development And Implementation Of “Mission Nutrition”: An After-School Nutrition Education Program For Youth Grades Kindergarten Through Fifth, Rachel Maloy

Honors Program: Senior Projects (Public)

Childhood overweight, obesity, and food insecurity are serious problems that are especially prevalent in low-income areas. Belmont Elementary School serves many children from low-income households (classified as a Title I school with 82.6% of students receiving free or reduced-price lunch) and, thus, was a perfect setting for the birth of an original nutrition curriculum.

A six-week after-school nutrition education program called “Mission Nutrition” was developed and implemented at Belmont Elementary School over the course of three and a half years. While originally designed for third through fifth grade students, the program was adapted for kindergarten, first, and second grade students …


Breakfast Consumption Is Positively Associated With Usual Nutrient Intakes Among Food Pantry Clients Living In Rural Communities, Yibin Liu, Janet A. Tooze, Yumin Zhang, Heather J. Leidy, Regan L. Bailey, Breanne Wright, Mengran Ma, Suzanne Stluka, Dan T. Remley, Lacey A. Mccormack, Lisa Franzen-Castle, Rebecca Henne, Donna Mehrle, Heather A. Eicher-Miller Sep 2019

Breakfast Consumption Is Positively Associated With Usual Nutrient Intakes Among Food Pantry Clients Living In Rural Communities, Yibin Liu, Janet A. Tooze, Yumin Zhang, Heather J. Leidy, Regan L. Bailey, Breanne Wright, Mengran Ma, Suzanne Stluka, Dan T. Remley, Lacey A. Mccormack, Lisa Franzen-Castle, Rebecca Henne, Donna Mehrle, Heather A. Eicher-Miller

Department of Nutrition and Health Sciences: Faculty Publications

Background: Breakfast consumption has declined over the past 40 y and is inversely associated with obesity-related diet and health outcomes. The breakfast pattern of food pantry clients and its association with diet is unknown.

Objective: The objective is to investigate the association of breakfast consumption with diet quality and usual nutrient intakes among food pantry clients (n = 472) living in rural communities.

Methods: This was an observational study using cross-sectional analyses. English-speaking participants ≥18 y (or ≥19 y in Nebraska) were recruited from 24 food pantries in rural high-poverty counties in Indiana, Michigan, Missouri, Nebraska, …


Sex-Specific Relationships Among Iron Status Biomarkers, Athletic Performance, Maturity, And Dietary Intakes In Pre-Adolescent And Adolescent Athletes, Marni E. Shoemaker, Zachary M. Gillen, Brianna D. Mckay, Nicholas A. Bohannon, Sydney M. Gibson, Karsten Koehler, Joel T. Cramer Sep 2019

Sex-Specific Relationships Among Iron Status Biomarkers, Athletic Performance, Maturity, And Dietary Intakes In Pre-Adolescent And Adolescent Athletes, Marni E. Shoemaker, Zachary M. Gillen, Brianna D. Mckay, Nicholas A. Bohannon, Sydney M. Gibson, Karsten Koehler, Joel T. Cramer

Department of Nutrition and Health Sciences: Faculty Publications

Background: The purpose of this study was to examine relationships among biomarkers of iron status, athletic performance, growth and development, and dietary intakes in pre-adolescent and adolescent male and female athletes.

Methods: Two-hundred and forty-nine male (n = 179) (mean ± standard deviation for age = 12.0 ± 2.1 years, height = 156.3 ± 13.9 cm, and weight = 49.1 ± 16.5 kg) and female (n = 70) (12.0 ± 2.2 years, 152.4 ± 12.3 cm, 45.3 ± 14.5 kg) athletes volunteered for capillary blood sample, anthropometric, athletic performance, and dietary intake assessments. Outcomes included maturity offset from peak height …


Omega-3 Fatty Acid-Derived Resolvin D2 Regulates Human Placental Vascular Smooth Muscle And Extravillous Trophoblast Activities, Arzu Ulu, Prakash K. Sahoo, Ana G. Yuil-Valdes, Maheswari Mukherjee, Matthew Van Ormer, Philma Glora Muthuraj, Maranda Thompson, Ann Anderson Berry, Corrine K. Hanson, Sathish Kumar Natarajan, Tara M. Nordgren Sep 2019

Omega-3 Fatty Acid-Derived Resolvin D2 Regulates Human Placental Vascular Smooth Muscle And Extravillous Trophoblast Activities, Arzu Ulu, Prakash K. Sahoo, Ana G. Yuil-Valdes, Maheswari Mukherjee, Matthew Van Ormer, Philma Glora Muthuraj, Maranda Thompson, Ann Anderson Berry, Corrine K. Hanson, Sathish Kumar Natarajan, Tara M. Nordgren

Department of Nutrition and Health Sciences: Faculty Publications

Omega-3 fatty acids are important to pregnancy and neonatal development and health. One mechanism by which omega-3 fatty acids exert their protective effects is through serving as substrates for the generation of specialized pro-resolving lipid mediators (SPM) that potently limit and resolve inflammatory processes. We recently identified that SPM levels are increased in maternal blood at delivery as compared to umbilical cord blood, suggesting the placenta as a potential site of action for maternal SPM. To explore this hypothesis, we obtained human placental samples and stained for the SPM resolvin D2 (RvD2) receptor GPR18 via immunohistochemistry. In so doing, we …


A Multi-Year Examination Of Gardening Experience And Fruit And Vegetable Intake During College, Daniel Staub, Sarah Colby, Melissa D. Olfert, Kendra Kattelmann, Wenjun Zhou, Tanya M. Horacek, Geoffrey W. Greene, Ivana Radosavljevic, Lisa Franzen-Castle, Anne E. Matthews Sep 2019

A Multi-Year Examination Of Gardening Experience And Fruit And Vegetable Intake During College, Daniel Staub, Sarah Colby, Melissa D. Olfert, Kendra Kattelmann, Wenjun Zhou, Tanya M. Horacek, Geoffrey W. Greene, Ivana Radosavljevic, Lisa Franzen-Castle, Anne E. Matthews

Department of Nutrition and Health Sciences: Faculty Publications

Gardening has been positively associated with fruit and vegetable (FV) consumption based on short-term studies among children, but long-term data among adolescents and young adults are lacking. This investigation sought to elucidate the association between gardening experience and FV intake among college students over a two-year period. Students (N = 593) from eight universities were assessed at the end of their freshman (Y1) and sophomore (Y2) years during the springs of 2016 and 2017, respectively. At each time point, participants completed the NCI FV Screener and questions related to gardening experience and FV-related attitudes and behaviors. Students were then categorized …