Open Access. Powered by Scholars. Published by Universities.®

Computational Neuroscience Commons

Open Access. Powered by Scholars. Published by Universities.®

Selected Works

PDF

Discipline
Keyword
Publication Year
Publication

Articles 1 - 30 of 79

Full-Text Articles in Computational Neuroscience

Microarray Gene Expression Profiles Of Fasting Induced Changes In Liver And Adipose Tissues Of Pigs Expressing The Melanocortin-4 Receptor D298n Variant, Sender Lkhagvadorj, Long Qu, Weiguo Cai, Oliver P. Coutoure, C. Richard Barb, Gary J. Hausman, Dan Nettleton, Lloyd L. Anderson, Jack C. M. Dekkers, Christopher K. Tuggle Jul 2019

Microarray Gene Expression Profiles Of Fasting Induced Changes In Liver And Adipose Tissues Of Pigs Expressing The Melanocortin-4 Receptor D298n Variant, Sender Lkhagvadorj, Long Qu, Weiguo Cai, Oliver P. Coutoure, C. Richard Barb, Gary J. Hausman, Dan Nettleton, Lloyd L. Anderson, Jack C. M. Dekkers, Christopher K. Tuggle

Dan Nettleton

Transcriptional profiling coupled with blood metabolite analyses were used to identify porcine genes and pathways that respond to a fasting treatment or to a D298N missense mutation in the melanocortin-4 receptor (MC4R) gene. Gilts (12 homozygous for D298 and 12 homozygous for N298) were either fed ad libitum or fasted for 3 days. Fasting decreased body weight, backfat, and serum urea concentration and increased serum nonesterified fatty acid. In response to fasting, 7,029 genes in fat and 1,831 genes in liver were differentially expressed (DE). MC4R genotype did not significantly affect gene expression, body weight, backfat depth, or any measured …


Mapping Molecular Datasets Back To The Brain Regions They Are Extracted From: Remembering The Native Countries Of Hypothalamic Expatriates And Refugees, Arshad M. Khan, Alice H. Grant, Anais Martinez, Gully Apc Burns, Brendan S. Thatcher, Vishwanath T. Anekonda, Benjamin W. Thompson, Zachary S. Roberts, Daniel H. Moralejo, James E. Blevins Jun 2018

Mapping Molecular Datasets Back To The Brain Regions They Are Extracted From: Remembering The Native Countries Of Hypothalamic Expatriates And Refugees, Arshad M. Khan, Alice H. Grant, Anais Martinez, Gully Apc Burns, Brendan S. Thatcher, Vishwanath T. Anekonda, Benjamin W. Thompson, Zachary S. Roberts, Daniel H. Moralejo, James E. Blevins

Arshad M. Khan, Ph.D.

This article, which includes novel unpublished data along with commentary and analysis,
focuses on approaches to link transcriptomic, proteomic, and peptidomic datasets mined from
brain tissue to the original locations within the brain that they are derived from using digital atlas
mapping techniques. We use, as an example, the transcriptomic, proteomic and peptidomic
analyses conducted in the mammalian hypothalamus. Following a brief historical overview, we
highlight studies that have mined biochemical and molecular information from the hypothalamus
and then lay out a strategy for how these data can be linked spatially to the mapped locations in a
canonical brain atlas …


Brain Function Differences In Language Processing In Children And Adults With Autism, Diane L. Williams, Vladimir L. Cherkassky, Robert A. Mason, Timothy A. Keller, Nancy J. Minshew, Marcel Adam Just Dec 2012

Brain Function Differences In Language Processing In Children And Adults With Autism, Diane L. Williams, Vladimir L. Cherkassky, Robert A. Mason, Timothy A. Keller, Nancy J. Minshew, Marcel Adam Just

Marcel Adam Just

No abstract provided.


Robust Dynamic Balance Of Ap-1 Transcription Factors In A Neuronal Gene Regulatory Network., Gregory M Miller, Babatunde A Ogunnaike, James S Schwaber, Rajanikanth Vadigepalli May 2012

Robust Dynamic Balance Of Ap-1 Transcription Factors In A Neuronal Gene Regulatory Network., Gregory M Miller, Babatunde A Ogunnaike, James S Schwaber, Rajanikanth Vadigepalli

Rajanikanth Vadigepalli

BACKGROUND: The octapeptide Angiotensin II is a key hormone that acts via its receptor AT1R in the brainstem to modulate the blood pressure control circuits and thus plays a central role in the cardiac and respiratory homeostasis. This modulation occurs via activation of a complex network of signaling proteins and transcription factors, leading to changes in levels of key genes and proteins. AT1R initiated activity in the nucleus tractus solitarius (NTS), which regulates blood pressure, has been the subject of extensive molecular analysis. But the adaptive network interactions in the NTS response to AT1R, plausibly related to the development of …


Distinctive Neural Processes During Learning In Autism, Sarah Schipul, Diane Williams, Timothy Keller, Nancy Minshew, Marcel Just Dec 2011

Distinctive Neural Processes During Learning In Autism, Sarah Schipul, Diane Williams, Timothy Keller, Nancy Minshew, Marcel Just

Marcel Adam Just

No abstract provided.


Brain Activation For Language Dual-Tasking: Listening To Two People Speak At The Same Time And A Change In Network Timing, Augusto Buchweitz, Timothy Keller, Ann Meyler, Marcel Just Dec 2011

Brain Activation For Language Dual-Tasking: Listening To Two People Speak At The Same Time And A Change In Network Timing, Augusto Buchweitz, Timothy Keller, Ann Meyler, Marcel Just

Marcel Adam Just

No abstract provided.


Autism As A Neural Systems Disorder: A Theory Of Frontal-Posterior Underconnectivity, Marcel Just, Timothy Keller, Vicente Malave, Rajesh Kana, Sashank Varma Dec 2011

Autism As A Neural Systems Disorder: A Theory Of Frontal-Posterior Underconnectivity, Marcel Just, Timothy Keller, Vicente Malave, Rajesh Kana, Sashank Varma

Marcel Adam Just

No abstract provided.


An Fmri Investigation Of Analogical Mapping In Metaphor Comprehension: The Influence Of Context And Individual Cognitive Capacities On Processing Demands., Chantel Prat, Robert Mason, Marcel Just Dec 2011

An Fmri Investigation Of Analogical Mapping In Metaphor Comprehension: The Influence Of Context And Individual Cognitive Capacities On Processing Demands., Chantel Prat, Robert Mason, Marcel Just

Marcel Adam Just

No abstract provided.


Exploring Commonalities Across Participants In The Neural Representation Of Objects, Svetlana V. Shinkareva, Vicente L. Malave, Marcel Adam Just, Tom M. Mitchell Dec 2011

Exploring Commonalities Across Participants In The Neural Representation Of Objects, Svetlana V. Shinkareva, Vicente L. Malave, Marcel Adam Just, Tom M. Mitchell

Marcel Adam Just

No abstract provided.


Identifying Bilingual Semantic Neural Representations Across Languages, Augusto Buchweitz, Svetlana V. Shinkareva, Robert A. Mason, Tom M. Mitchell, Marcel Adam Just Dec 2011

Identifying Bilingual Semantic Neural Representations Across Languages, Augusto Buchweitz, Svetlana V. Shinkareva, Robert A. Mason, Tom M. Mitchell, Marcel Adam Just

Marcel Adam Just

No abstract provided.


Differentiable Cortical Networks For Inferences Concerning People’S Intentions Versus Physical Causality, Robert Mason, Marcel Just Dec 2010

Differentiable Cortical Networks For Inferences Concerning People’S Intentions Versus Physical Causality, Robert Mason, Marcel Just

Marcel Adam Just

No abstract provided.


Autonomy Of Lower-Level Perception From Global Processing In Autism: Evidence From Brain Activation And Functional Connectivity, Yanni Liu, Vladimir L. Cherkassky, Nancy J. Minshew, Marcel Adam Just Dec 2010

Autonomy Of Lower-Level Perception From Global Processing In Autism: Evidence From Brain Activation And Functional Connectivity, Yanni Liu, Vladimir L. Cherkassky, Nancy J. Minshew, Marcel Adam Just

Marcel Adam Just

No abstract provided.


Inter-Regional Brain Communication And Its Disturbance In Autism, Sarah E. Schipul, Timothy A. Keller, Marcel Adam Just Dec 2010

Inter-Regional Brain Communication And Its Disturbance In Autism, Sarah E. Schipul, Timothy A. Keller, Marcel Adam Just

Marcel Adam Just

No abstract provided.


Quantitative Modeling Of The Neural Representation Of Objects: How Semantic Feature Norms Can Account For Fmri Activation, Kai-Min Kevin Chang, Tom Mitchell, Marcel Adam Just Dec 2010

Quantitative Modeling Of The Neural Representation Of Objects: How Semantic Feature Norms Can Account For Fmri Activation, Kai-Min Kevin Chang, Tom Mitchell, Marcel Adam Just

Marcel Adam Just

No abstract provided.


Individual Differences In The Neural Basis Of Causal Inferencing, Chantel S. Prat, Robert A. Mason, Marcel Adam Just Dec 2010

Individual Differences In The Neural Basis Of Causal Inferencing, Chantel S. Prat, Robert A. Mason, Marcel Adam Just

Marcel Adam Just

No abstract provided.


Commonality Of Neural Representations Of Words And Pictures, Svetlana V. Shinkareva, Vincente L. Malave, Robert A. Mason, Tom M. Mitchell, Marcel Adam Just Dec 2010

Commonality Of Neural Representations Of Words And Pictures, Svetlana V. Shinkareva, Vincente L. Malave, Robert A. Mason, Tom M. Mitchell, Marcel Adam Just

Marcel Adam Just

No abstract provided.


The Neural Basis Of Deictic Shifting In Linguistic Perspective-Taking In High-Functioning Autism, Akiko Mizuno, Yanni Liu, Diane L. Williams, Timothy A. Keller, Nancy J. Minshew, Marcel Adam Just Dec 2010

The Neural Basis Of Deictic Shifting In Linguistic Perspective-Taking In High-Functioning Autism, Akiko Mizuno, Yanni Liu, Diane L. Williams, Timothy A. Keller, Nancy J. Minshew, Marcel Adam Just

Marcel Adam Just

No abstract provided.


Exploring The Neural Dynamics Underpinning Individual Differences In Sentence Comprehension, Chantel S. Prat, Marcel Adam Just Dec 2010

Exploring The Neural Dynamics Underpinning Individual Differences In Sentence Comprehension, Chantel S. Prat, Marcel Adam Just

Marcel Adam Just

No abstract provided.


Cortical Underconnectivity Coupled With Preserved Visuospatial Cognition In Autism: Evidence From An Fmri Study Of An Embedded Figures Task, Saudamini Damarla, Timothy A. Keller, Rajesh K. Kana, Vladimir L. Cherkassky, Diane L. Williams, Nancy J. Minshew, Marcel Adam Just Dec 2009

Cortical Underconnectivity Coupled With Preserved Visuospatial Cognition In Autism: Evidence From An Fmri Study Of An Embedded Figures Task, Saudamini Damarla, Timothy A. Keller, Rajesh K. Kana, Vladimir L. Cherkassky, Diane L. Williams, Nancy J. Minshew, Marcel Adam Just

Marcel Adam Just

No abstract provided.


A Neurosemantic Theory Of Concrete Noun Representation Based On The Underlying Brain Codes, Marcel Adam Just, Vladimir L. Cherkassky, Sandesh Aryal, Tom M. Mitchell Dec 2009

A Neurosemantic Theory Of Concrete Noun Representation Based On The Underlying Brain Codes, Marcel Adam Just, Vladimir L. Cherkassky, Sandesh Aryal, Tom M. Mitchell

Marcel Adam Just

No abstract provided.


Brain Activation For Reading And Listening Comprehension: An Fmri Study Of Modality Effects And Individual Differences In Language Comprehension., Augusto Buchweitz, Robert Mason, Tomitch Leda, Marcel Just Dec 2008

Brain Activation For Reading And Listening Comprehension: An Fmri Study Of Modality Effects And Individual Differences In Language Comprehension., Augusto Buchweitz, Robert Mason, Tomitch Leda, Marcel Just

Marcel Adam Just

No abstract provided.


Altering Cortical Connectivity: Remediation-Induced Changes In The White Matter Of Poor Readers, Timothy Keller, Marcel Just Dec 2008

Altering Cortical Connectivity: Remediation-Induced Changes In The White Matter Of Poor Readers, Timothy Keller, Marcel Just

Marcel Adam Just

No abstract provided.


Japanese And English Sentence Reading Comprehension And Writing Systems: An Fmri Study Of First And Second Language Effects On Brain Activation, Augusto Buchweitz, Robert A. Mason, Akiko Hasegawa, Marcel Adam Just Dec 2008

Japanese And English Sentence Reading Comprehension And Writing Systems: An Fmri Study Of First And Second Language Effects On Brain Activation, Augusto Buchweitz, Robert A. Mason, Akiko Hasegawa, Marcel Adam Just

Marcel Adam Just

No abstract provided.


Atypical Frontal-Posterior Synchronization Of Theory Of Mind Regions In Autism During Mental State Attribution, Rajesh K. Kana, Timothy A. Keller, Vladimir L. Cherkassky, Nancy J. Minshew, Marcel Adam Just Dec 2008

Atypical Frontal-Posterior Synchronization Of Theory Of Mind Regions In Autism During Mental State Attribution, Rajesh K. Kana, Timothy A. Keller, Vladimir L. Cherkassky, Nancy J. Minshew, Marcel Adam Just

Marcel Adam Just

No abstract provided.


The Role Of The Theory-Of-Mind Cortical Network In The Comprehension Of Narratives, Robert Mason, Marcel Just Dec 2008

The Role Of The Theory-Of-Mind Cortical Network In The Comprehension Of Narratives, Robert Mason, Marcel Just

Marcel Adam Just

No abstract provided.


Brain Bases Of Individual Differences In Cognition, Chantel Prat, Marcel Just Dec 2007

Brain Bases Of Individual Differences In Cognition, Chantel Prat, Marcel Just

Marcel Adam Just

No abstract provided.


A Decrease In Brain Activation Associated With Driving When Listening To Someone Speak, Marcel Just, Timothy Keller, Jacquelyn Cynkar Dec 2007

A Decrease In Brain Activation Associated With Driving When Listening To Someone Speak, Marcel Just, Timothy Keller, Jacquelyn Cynkar

Marcel Adam Just

No abstract provided.


Fmri Investigation Of Working Memory For Faces In Autism: Visual Coding And Underconnectivity With Frontal Areas, Hideya Koshino, Rajesh Kana, Timothy Keller, Vladimir Cherkassky, Nancy Minshew, Marcel Just Dec 2007

Fmri Investigation Of Working Memory For Faces In Autism: Visual Coding And Underconnectivity With Frontal Areas, Hideya Koshino, Rajesh Kana, Timothy Keller, Vladimir Cherkassky, Nancy Minshew, Marcel Just

Marcel Adam Just

No abstract provided.


Using Fmri Brain Activation To Identify Cognitive States Associated With Perception Of Tools And Dwellings, Svetlana V. Shinkareva, Robert A. Mason, Vicente L. Malave, Wei Wang, Tom M. Mitchell, Marcel Adam Just Dec 2007

Using Fmri Brain Activation To Identify Cognitive States Associated With Perception Of Tools And Dwellings, Svetlana V. Shinkareva, Robert A. Mason, Vicente L. Malave, Wei Wang, Tom M. Mitchell, Marcel Adam Just

Marcel Adam Just

No abstract provided.


Modifying The Brain Activation Of Poor Readers During Sentence Comprehension With Extended Remedial Instruction: A Longitudinal Study Of Neuroplasticity, Ann Meyler, Timothy A. Keller, Vladimir L. Cherkassky, John D. E. Gabrieli, Marcel Adam Just Dec 2007

Modifying The Brain Activation Of Poor Readers During Sentence Comprehension With Extended Remedial Instruction: A Longitudinal Study Of Neuroplasticity, Ann Meyler, Timothy A. Keller, Vladimir L. Cherkassky, John D. E. Gabrieli, Marcel Adam Just

Marcel Adam Just

No abstract provided.