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Full-Text Articles in Computational Neuroscience
Impact Of Brain State On Visual And Prefrontal Population Coding In Behaving Animals, Russell Milton
Impact Of Brain State On Visual And Prefrontal Population Coding In Behaving Animals, Russell Milton
Dissertations & Theses (Open Access)
Patterns of neural activity in the brain constantly shift between different processing states. Earlier studies have established that the ongoing, spontaneous activity has major repercussions regarding how the brain processes incoming sensory stimuli. However, the interaction between behavioral activity and brain states throughout the cortical hierarchy of primates has not been understood. In particular, technical considerations have greatly limited the range of physical activities in which primate neuronal activity can be recorded. We have implemented two separate strategies to overcome these limitations. First, we have advanced wireless electrophysiological methodologies that enable recording high-yield neuronal data from animals as they freely …
The Impact Of Cortical State On Neural Coding And Behavior, Charles Beaman
The Impact Of Cortical State On Neural Coding And Behavior, Charles Beaman
Dissertations & Theses (Open Access)
The brain is never truly silent – up to 80% of its energy budget is expended during ongoing activity in the absence of sensory input. Previous research has shown that sensory neurons are not exclusively influenced by external stimuli but rather reflect interactions between sensory inputs and the ongoing activity of the brain. Yet, whether fluctuations in the state of cortical networks influence sensory coding in neural circuits and the behavior of the animal are unknown. To shed light on this issue, we conducted multi-unit electrophysiology experiments in visual areas V1 and V4 of behaving monkeys. First, we studied the …