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Articles 1 - 4 of 4
Full-Text Articles in Computational Neuroscience
The Effect Of The R1648h Sodium Channel Mutation On Neuronal Excitability: A Model Study, Christopher Locandro, Robert Clewley
The Effect Of The R1648h Sodium Channel Mutation On Neuronal Excitability: A Model Study, Christopher Locandro, Robert Clewley
Georgia State Undergraduate Research Conference
No abstract provided.
Switching Bistable Leech Heart Interneurons With A Pulse Of Current From Bursting To Silence, Aaron Gomez-Lugo
Switching Bistable Leech Heart Interneurons With A Pulse Of Current From Bursting To Silence, Aaron Gomez-Lugo
Georgia State Undergraduate Research Conference
No abstract provided.
Resiliency To Bistability In The Neurons From The Pre-Bötzinger Complex, Treadwell D. Singfield Ii
Resiliency To Bistability In The Neurons From The Pre-Bötzinger Complex, Treadwell D. Singfield Ii
Georgia State Undergraduate Research Conference
No abstract provided.
Rescuing Acetylcholinesterase From Nerve Agent Inhibition: Protein Dynamics Driven Drug Discovery, Aiyana M. Emigh, Brian Bennion
Rescuing Acetylcholinesterase From Nerve Agent Inhibition: Protein Dynamics Driven Drug Discovery, Aiyana M. Emigh, Brian Bennion
STAR Program Research Presentations
Severe morbidity and mortality consequences result from irreversible inhibition of human acetylcholinesterase by organophosphates (OPs). Oxime-based reactivators are currently the only available treatments but lack efficacy in the central nervous system (CNS) where the most damage occurs. Computational docking and molecular dynamics (MD) simulations reveal complex structural barriers that may reduce oxime efficacy. These results may guide future drug designs of more effective countermeasures.