Neuroscience and Neurobiology Commons^™

Resistance Training Improves White Matter Structural Connectivity In Older Adults At-Risk For Cognitive Decline, Ryu Lien

Undergraduate Student Research Internships Conference

Diabetes is a global health concern that impacts 415 million people worldwide. Individuals who are at-risk for diabetes (characterized by high blood glucose and/or being overweight) have white matter atrophy, decreased cognitive function, and an increased risk of Alzheimer’s disease (AD). Recently, resistance training (RT) has been shown to lower white matter atrophy and white matter lesion volume. However, investigating changes in white matter tracts is complex, hence previous findings remain inconclusive. Diffusion tensor imaging (DTI) serves as a highly sensitive tool that enables visualization and characterization of white matter tracts and has the potential to combat this complexity. The …

Human Claustrum Activation During Pain, Zoravar S. Sidhu, David A. Seminowicz, Brent W. Stewart

Undergraduate Student Research Internships Conference

Chronic pain is one of the principal causes of disability in the world. Many if not all of us deal with or know of someone who deals with chronic pain. Interestingly, it appears that a mysterious part of the brain known as the claustrum has a hand in chronic pain. Although little is known about the actual function of the claustrum, it is hypothesized to synchronize cortical networks during tasks which have a cognitive load.

Recent literature has indicated that during chronic pain conditions, neural network recruitment is modified. In addition, an analysis of an existing fMRI data set determined …