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Effects Of Myosuppressin, A Peptide Neuromodulator, On Membrane Currents In The Crustacean Cardiac Ganglion, Anthony Yanez

Honors Projects

Central pattern generators are neural circuits that can independently produce rhythmic patterns of electrical activity without central or periphery inputs. They control rhythmic behaviors like breathing in humans and cardiac activity in crustaceans. Rhythmic behaviors must be flexible to respond appropriately to a changing environment; this flexibility is achieved through the action of neuromodulators. The cardiac ganglion of Homarus americanus, the American lobster, is a central pattern generator made up of four premotor neurons and five motor neurons. Membrane currents in each cell type, which can be targeted for modulation by various molecules, generate rhythmic bursts of action potentials. …