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Full-Text Articles in Neuroscience and Neurobiology
Neurosteroid Replacement Therapy For Catamenial Epilepsy, Doodipala S. Reddy, Michael A. Rogawski
Neurosteroid Replacement Therapy For Catamenial Epilepsy, Doodipala S. Reddy, Michael A. Rogawski
Michael A. Rogawski
Perimenstural catamenial epilepsy, the cyclical occurrence of seizure exacerbations near the time of menstruation, affects a high proportion of women of reproductive age with drug refractory epilepsy. Enhanced seizure susceptibility in perimenstrual catamenial epilepsy is believed to be due to the withdrawal of the progesterone-derived GABA-A receptor modulating neurosteroid allopregnanolone as a result of the fall in progesterone at the time of menstruation. Studies in a rat pseudopregnancy model of catamenial epilepsy indicate that following neurosteroid withdrawal there is enhanced susceptibility to chemoconvulsant seizures. There is also a transitory increase in the frequency of spontaneous seizures in epleptic rats that …
Farm Focus - Spring 2009, Brian K. Whitlock, Matt Welborn, Maria Prado, Amy Plummer
Farm Focus - Spring 2009, Brian K. Whitlock, Matt Welborn, Maria Prado, Amy Plummer
Brian K Whitlock, PhD, DVM, DACT
No abstract provided.
Farm Focus - Fall 2009, Brian K. Whitlock, Matt Welborn, Maria Prado, Amy Plummer
Farm Focus - Fall 2009, Brian K. Whitlock, Matt Welborn, Maria Prado, Amy Plummer
Brian K Whitlock, PhD, DVM, DACT
No abstract provided.
"The Natural History Of Truth: The Neurobiology Of Belief", Neil Greenberg
"The Natural History Of Truth: The Neurobiology Of Belief", Neil Greenberg
Neil Greenberg
The pursuit of truth is woven into the fabric of every organism*. Any estimate of how best to survive and thrive in the reality in which we are immersed requires a sense of self, of the world, and of their relationship to each other. I wish to explore the idea that this pursuit has at its heart two complementary modes of reality testing utilizing separate cerebral systems which deal, respectively with the correspondence of experience with the world and the coherence of the experience with previous experiences: “is it real” and “does it fit?” At multiple levels of the nervous …