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Full-Text Articles in Neuroscience and Neurobiology

Brain Mappings Of The Arithmetic Processing In Children And Adults., Fábio T. Rocha, Armando F. Rocha, Eduardo Massad, Renee Menezes Jan 2005

Brain Mappings Of The Arithmetic Processing In Children And Adults., Fábio T. Rocha, Armando F. Rocha, Eduardo Massad, Renee Menezes

Armando F Rocha

Despite the increasing number of experimental mapping showing that human arithmetic cognition is supported by widely spread neural circuits; the theoretical reasoning about these data remains mostly metaphorical and guided by a connectionist approach. Although neurons at distinct areas in the brain are assumed to take charge of different duties in the solution of the experimental task, the results are always discussed by hypothesizing some association between the different areas without questioning any difference of behavior at the level of the neurons at each of these areas. Here, the brain is assumed as Distributed Intelligent Processing System (DIPS) formed by …


Stress Enhancement Of Craving During Sobriety: A Risk For Relapse, Laura O'Dell Jan 2005

Stress Enhancement Of Craving During Sobriety: A Risk For Relapse, Laura O'Dell

Laura Elena O'Dell

No abstract provided.


Epipregnanolone And A Novel Synthetic Neuroactive Steroid Reduce Reduce Alcohol Self-Administration In Rats., Laura O'Dell Jan 2005

Epipregnanolone And A Novel Synthetic Neuroactive Steroid Reduce Reduce Alcohol Self-Administration In Rats., Laura O'Dell

Laura Elena O'Dell

No abstract provided.


Interaction Between The Dorsal And Ventral Pathways In Mental Rotation: An Fmri Study, Hideya Koshino, Patricia Carpenter, Timothy Keller, Marcel Just Dec 2004

Interaction Between The Dorsal And Ventral Pathways In Mental Rotation: An Fmri Study, Hideya Koshino, Patricia Carpenter, Timothy Keller, Marcel Just

Marcel Adam Just

No abstract provided.


Imagining Material Versus Geometric Properties Of Objects: An Fmri Study, Sharlene Newman, Roberta Klatzky, Susan Lederman, Marcel Just Dec 2004

Imagining Material Versus Geometric Properties Of Objects: An Fmri Study, Sharlene Newman, Roberta Klatzky, Susan Lederman, Marcel Just

Marcel Adam Just

No abstract provided.


Nonclassical, Distinct Endocytic Signals Dictate Constitutive And Pkc-Regulated Neurotransmitter Transporter Internalization, Haley Melikian Dec 2004

Nonclassical, Distinct Endocytic Signals Dictate Constitutive And Pkc-Regulated Neurotransmitter Transporter Internalization, Haley Melikian

Haley Melikian

Neurotransmitter transporters are critical for synaptic neurotransmitter inactivation. Transporter inhibitors markedly increase the duration and magnitude of synaptic transmission, underscoring the importance of transporter activity in neurotransmission. Recent studies indicate that membrane trafficking dynamically governs neuronal transporter cell-surface presentation in a protein kinase C-regulated manner, suggesting that transporter trafficking profoundly affects synaptic signaling. However, the molecular architecture coupling neurotransmitter transporters to the endocytic machinery is not defined. Here, we identify nonclassical, distinct endocytic signals in the dopamine transporter (DAT) that are necessary and sufficient to drive constitutive and protein kinase C-regulated DAT internalization. The DAT internalization signal is conserved across …


Functional Connectivity In An Fmri Working Memory Task In High-Functioning Autism, Hideya Koshino, Patricia Carpenter, Nancy Minshew, Vladimir Cherkassky, Timothy Keller, Marcel Just Dec 2004

Functional Connectivity In An Fmri Working Memory Task In High-Functioning Autism, Hideya Koshino, Patricia Carpenter, Nancy Minshew, Vladimir Cherkassky, Timothy Keller, Marcel Just

Marcel Adam Just

No abstract provided.


Single-Channel Properties Of Human Nav1.1 And Mechanism Of Channel Dysfunction In Scn1a-Associated Epilepsy, C. Vanoye, Christoph Lossin, T. H. Rhodes, Alfred L. George Dec 2004

Single-Channel Properties Of Human Nav1.1 And Mechanism Of Channel Dysfunction In Scn1a-Associated Epilepsy, C. Vanoye, Christoph Lossin, T. H. Rhodes, Alfred L. George

Christoph Lossin, Ph.D.

Mutations in genes encoding neuronal voltage-gated sodium channel subunits have been linked to inherited forms of epilepsy. The majority of mutations (>100) associated with generalized epilepsy with febrile seizures plus (GEFS+) and severe myoclonic epilepsy of infancy (SMEI) occur in SCN1A encoding the NaV1.1 neuronal sodium channel alpha-subunit. Previous studies demonstrated functional heterogeneity among mutant SCN1A channels, revealing a complex relationship between clinical and biophysical phenotypes. To further understand the mechanisms responsible for mutant SCN1A behavior, we performed a comprehensive analysis of the single-channel properties of heterologously expressed recombinant WT-SCN1A channels. Based on these data, we then determined the …


The Framing Effect And Risky Decisions: Examining Cognitive Functions With Fmri, Cleotilde Gonzalez, Jason Dana, Hideya Koshino, Marcel Adam Just Dec 2004

The Framing Effect And Risky Decisions: Examining Cognitive Functions With Fmri, Cleotilde Gonzalez, Jason Dana, Hideya Koshino, Marcel Adam Just

Marcel Adam Just

No abstract provided.