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Full-Text Articles in Neuroscience and Neurobiology
Investigation Of Neural Mechanisms Of Grip Relaxation, Binal Motawar
Investigation Of Neural Mechanisms Of Grip Relaxation, Binal Motawar
Theses and Dissertations
Neural mechanisms for grip relaxation are relatively unknown and understudied, as compared to mechanisms for grip initiation. Yet, termination of motor activity is as important as initiation in daily function. This knowledge gap presents incomplete understanding of neural control of hand function and its impairment with aging and neurologic disorders. The purpose of this dissertation was to identify and examine neural mechanisms of grip relaxation in healthy young adults, with aging, and in chronic stroke survivors. A series of experiments in healthy young adults showed that the relaxation from a maximum power grip was mediated by increase in the short-interval …
Lesion Identification And The Effect Of Lesion On Motor Mapping After Stroke, Ruixi Zhou
Lesion Identification And The Effect Of Lesion On Motor Mapping After Stroke, Ruixi Zhou
McKelvey School of Engineering Theses & Dissertations
Stroke is the most common cause of long-term severe disability and the motor system that is most commonly affected in stroke. One of the mechanisms that underlies recovery of motor deficits is reorganization or remapping of functional representations around the motor cortex. This mechanism has been shown in monkeys, but results in human subjects have been variable. In this thesis, I used a database that includes longitudinal behavioral and multimodal imaging data in both stroke patients and healthy controls for two research projects. Firstly, I improved an automatic lesion segmentation method to aid in the identification of the location and …
The Effects Of Cognitive Rehabilitation For Improving Prospective Memory In Acquired Brain Injury, Emily M. Aiken
The Effects Of Cognitive Rehabilitation For Improving Prospective Memory In Acquired Brain Injury, Emily M. Aiken
Masters Theses
Acquired Brain Injury (ABI) includes any damage to the brain resulting from traumatic (e.g. motor vehicle accident) or non-traumatic (e.g. stroke) incidence, that occurs after birth and is not resulting from genetic or congenital factors. Individuals with ABI report that prospective memory (PM) deficits are the most detrimental cognitive impairment following injury, persistently and negatively impacting their ability to function properly in everyday life. PM refers to the ability to remember to carry out intended tasks in the future, including the recall of both time and event regulated intentions. Using neuropsychological assessments to produce patient deficit profiles, this study examines …
Sex Differences In Stroke Recovery: Synaptic Proteins And The Growth Inhibitory Protein Nogo A, Vincent Joseph Borkowski
Sex Differences In Stroke Recovery: Synaptic Proteins And The Growth Inhibitory Protein Nogo A, Vincent Joseph Borkowski
Dissertations
Ischemic stroke is a major world-wide health problem, resulting in death and disability especially in the older population. A sex difference exists in functional recovery post-stroke, with post-menopausal women having worse functional outcome as compared to age-matched men. Although the mechanisms underlying this sex difference are not entirely clear, it is recommended that any potential therapy for stroke recovery be tested in pre-clinical models including both male and females in order to determine the efficacy of the proposed treatment on the entire population. We have reported a novel therapy to enhance brain plasticity and improve functional recovery after stroke in …