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Full-Text Articles in Neuroscience and Neurobiology

Perceiving Oldness In Parietal Cortex: Fmri Characterization Of A Parietal Memory Network, Adrian Gilmore Aug 2016

Perceiving Oldness In Parietal Cortex: Fmri Characterization Of A Parietal Memory Network, Adrian Gilmore

Arts & Sciences Electronic Theses and Dissertations

The manner in which the human brain recognizes certain stimuli as novel or familiar is a matter of ongoing investigation. The overarching goal of this dissertation is to improve our understanding of how this may be accomplished. More specifically, work contained herein focuses on a recently described "parietal memory network" (PMN; Gilmore et al., 2015) that shows opposite patterns of activity when perceiving novel or familiar stimuli: deactivating in response to novelty, and activating in response to familiarity. Critically, our understanding of this network is based on explicit memory tasks, in which subjects are deliberately instructed to learn or remember …


Neural Circuitry Underlying The Intrusion Of Task-Irrelevant Threat Into Working Memory In Anxiety, Daniel Stout Aug 2016

Neural Circuitry Underlying The Intrusion Of Task-Irrelevant Threat Into Working Memory In Anxiety, Daniel Stout

Theses and Dissertations

Dispositional anxiety is an important risk factor for the development of anxiety and other psychological disorders. Symptoms commonly expressed by highly anxious individuals include intrusive memories, uncertainty, and worry — all occurring in the absence of immediate threat. This raises the possibility that anxious individuals have difficulty governing threat’s access to working memory, the mental workspace where goal-related information is actively retained for guiding on-going behavior. Using functional magnetic resonance imaging (fMRI) while 81 subjects completed a well-validated working memory task, I show that threat-related and neutral distracters unnecessarily gain access to working memory, as evidenced by increased neural activity …


The Effects Of Concurrent Cognitive Load On The Processing Of Clear And Degraded Speech, Harrison Ritz Jul 2016

The Effects Of Concurrent Cognitive Load On The Processing Of Clear And Degraded Speech, Harrison Ritz

Electronic Thesis and Dissertation Repository

A previous study has found that perceiving degraded speech requires attention, with compromised behavioral and neurological measures of speech processing for degraded speech, but not clear speech, when participants are distracted (Wild et al., 2012b). We extended these findings by examining behavioral and neural correlates of speech perception under different levels of cognitive load using multiple object tracking. We also investigated the role of attention in perceiving degraded speech that was as intelligible as clear speech, in order to separate perceptual outcomes (i.e., intelligibility) from the requisite processing demands. We found that the speech perception system is heterogeneous in its …


The Effects Of External Focus Of Attention Exercise Rehabilitation On Dual Task Walking In Parkinson's Disease, Eric N. Beck Jan 2016

The Effects Of External Focus Of Attention Exercise Rehabilitation On Dual Task Walking In Parkinson's Disease, Eric N. Beck

Theses and Dissertations (Comprehensive)

Parkinson’s disease impairs control of well-learned movements, and therefore, individuals with Parkinson’s disease are forced to walk with greater conscious control. This causes difficulties while walking and completing a secondary task simultaneously (dual tasking), in that distractions from conscious control of walking increase the risk of falls and injury. Although, attention-based exercise may be a potential avenue to decrease the demands associated with walking in Parkinson’s disease. For example, an external focus of attention (on manipulated objects) has been found to recruit the networks that are important for walking with little conscious control (automatic control networks). In contrast, an internal …