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Full-Text Articles in Neuroscience and Neurobiology
Ivermectin Activates Striatal Cholinergic Interneurons To Enhance Dopamine Release, Tyler Love, Jordan Yorgason, Hillary Wadsworth, Alicia Warnecke, Joshua Barlow, Emma Steimle, Joakim Ronström, Pacen Williams, Christopher Galbraith, Jared Baldridge, Michael Jakowec, Daryl Davies
Ivermectin Activates Striatal Cholinergic Interneurons To Enhance Dopamine Release, Tyler Love, Jordan Yorgason, Hillary Wadsworth, Alicia Warnecke, Joshua Barlow, Emma Steimle, Joakim Ronström, Pacen Williams, Christopher Galbraith, Jared Baldridge, Michael Jakowec, Daryl Davies
Library/Life Sciences Undergraduate Poster Competition 2024
• The substantia nigra compacta releases dopamine into the dorsal striatum, a brain region associated with movement and motivation
• Cholinergic interneurons in the dorsal striatum can directly cause dopamine release
• IVM is a known positive allosteric modulator of P2X4 receptors as well as nicotinic
• acetylcholine receptors
• Ivermectin is known to affect many dopamine linked behaviors, but no studies have been conducted to determine if Ivermectin is able to modulate dopamine release