Open Access. Powered by Scholars. Published by Universities.®
Neuroscience and Neurobiology Commons™
Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Neuroscience and Neurobiology
Characterization Of A Putative Glycinergic Nigropallidal Pathway In The Rodent Brain, Rosalia Ortega
Characterization Of A Putative Glycinergic Nigropallidal Pathway In The Rodent Brain, Rosalia Ortega
Open Access Theses & Dissertations
Glycinergic neurotransmission is essential for the function of sensory and motor systems associated with pain transmission and rhythmic motor patterns. Yet, the way glycinergic circuits modulates motor systems via the globus pallidus external (GPe) is not clear. The cyto-architecture of glycinergic circuitry is poorly understood and most work has focused in brainstem areas. It is believed that glycinergic neurons are mainly interneurons regulating local circuits. However, it is now becoming clear that they are also projection neurons, constituting true neuronal circuits. At the glycinergic synapse, termination of neurotransmission and recycling of glycine is regulated by two transporters, glycine transporter 1 …